In this paper

we have studied the effect of medicinal vesiculation on the hematopoietic function and its mechanism in mice treated by Cyclophosphamide (CTX). The results show that CTX can cause serious bone marrow inhibition of mouse

decrease significantly the number of karyocyte of bone marrow and WBC and the production ability of GM-CSF by abdominal cavity macrophage. Medicinal vesiculation or moxibustion of wheat grain form on "Dazhui"

"Shenshu" and "Zusanli" has significant effect on bone marrow inhibition caused by chemotherapy. It can promote bone marrow cell proliferation

increase the number of karyocyte of bone marrow and WBC significantly. It can also strengthen abdominal cavity macrophage cell to produce GM-CSF. Furthermore

we discussed the nerve-endocrine-immune machanism of the effect of medicinal vesiculation.