Guinea-pig model of allergic asthma was established by OVA. Animals were divided randomly into three groups which were normal
model and acupuncture group respectively. The results showed that: (1) The levels of TNF-α and ET in model group were higher than those of normal group. (2) The levels of TNF-α and ET inacupuncture group were markedly lower than those of model group. All the results suggested that acupuncture could inhibit the synthesis and secretion of TNF-αand ET
block the release of inflammatory mediator
abate inflammatory reaction in airway and remit spasm of trachea smooth muscle.