In this paper the clinical efficacies of HANS combined with PCB and HANS alone applicated for anesthesia in thyroid operation were observed in 80 cases. They were divided into two groups

group A (40 cases)

using HANS and PCB; group B(40 cases)

using HANS alone. Results: ①The satisfactory rate of anesthesia of group A was 93%

while group B was 75 %

the difference was significant(P < 0. 05 ). ②The changes of patients' HR

MAP

SpO_2 at 15 minutes before and after operation: In group A

HR

SpO_2 decreased after operation

which were more lower than that of preparation (P < 0. 01 ). MAP was also decreased significantly(p<0. 05). In group B

HR increased somewhat

but the difference was not marked(p >0. 05). MAP decreased

the difference was significant (P< 0. 05). SpoO_a2 decreased was significant (P < 0. 01 ). In group A

HR

MAP and SpO_2 decreased significantly after operation as compared with those in group B(P < 0. 01 ).