Relationship between the Change of Temperature and the Contents of CGRP and AⅡ in the Tissues along the Meridian in Rabbits[J]. Acupuncture research, 2002, (2): 149-151.
Relationship between the Change of Temperature and the Contents of CGRP and AⅡ in the Tissues along the Meridian in Rabbits[J]. Acupuncture research, 2002, (2): 149-151.DOI:
循经组织温度变化可能与外周组织CGRP功能活动有关Objective: To observe the correlation between temperature changes and CGRP and AⅡ contents in the tissues along the meridians in the rabbit. Methods: Domestic rabbits were used in the present study. After removing the hair On the bilateral hind-limbs
the local body surface temperature was detected before and after moxibustion of "Housanli" (for 15 min) using a infra-red thermography. The local skin
subcutaneous connective tissues and muscles where higher temperature band appeared along the meridian were taken for determining the contents of CGRP (calcitonin gene related peptide) and AⅡ (angiotensin Ⅱ) with radioimmunoassay. Results: The results showed that the content of CGRP in the higher temperature area tissues (14.9±9.11 pg/mg) was apparently higher than that (4.37±4.53 pg/mg)in the lower temperature area tissues (P<0.001); while no significant difference was found between higher and lower temperature area tissues in AⅡ contents (8.97±5.39 pg/mg vs 9.48±6.53 pg/mg
P>0.05). Conclusion: The results suggest that moxibustion induced increase of body surface temperature along the meridian is probably related to the release of CGRP in the peripheral tissue.