Objective: To observe clinical therapeutic effect of acupoint injection of compound Methylthioninum Chloride(CMC) for treating post-herpetic neuralgia(PHN).Methods: Eighty PHN patients were divided into treatment group(n=40)and control(acupuncture) group(n=40)with random number table method.For patients in treatment group

CMC injection((10 mL)) composed of 0.5% Bupivacaine Hydrochloride((3 mL))

Triamcinolone injection((15 mg))

VitB_(12)(1 mg)

VitB_6 injection((100 mg))

CMC((0.02 mg)) and normal saline((3 mL)) was injected into back-shu-points on the first lateral line of the Bladder Meridian and its upper and lower back-shu-points according to the location of herpes zoster

2-(3 mL/point)

followed by injecting oxygen((10 mL)) into the same point slowly

once every week

3 times altogether.For patients of control group

the same back-shu points were used and punctured with filiform needles

combined with acupuncture of Zhigou(TE 6)

Yanglingquan(GB 34)

etc.

once daily

continuously for 3 weeks.Results: Self-comparison showed that after the treatment 6-point-behavoral rating scale(BRS-6) scores of two groups both decreased significantly(P<0.001)

and the BRS-6 score of treatment group was significantly lower than that of control group(P<0.01).Of the 40 cases in treatment and control groups

32(80%) and 3(7.5%) cases were cured

6(15.0%) and 7(17.5%) markedly effective

1(2.5%) and 19(47.5%) effective

1(2.5%) and 11(27.5%) failed

with the total effective rates being 97.5% and 72.5% respectively.The therapeutic effect of treatment group was significantly superior to that of control group(P<0.001).Conclusion: The therapeutic effect of point-injection of compound Methylthioninum Chloride is significantly better than that of acupuncture therapy in the treatment of PHN patients.