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1. 广州中医药大学针灸推拿学院
2. 广州中医药大学针灸推拿学院,广州,510405
3. ,广州,510405
纸质出版日期:2006
移动端阅览
许云祥, 张家维. 电针对糖尿病性认知功能障碍患者学习记忆的影响[J]. 针刺研究, 2006,(4):232-234.
XU Yun-xiang, ZHANG Jia-wei. Influence of Electroacupuncture on Learning and Memory Ability in Diabetic Cognitive Dysfunction Patients[J]. Acupuncture research, 2006, (4): 232-234.
目的:观察电针对糖尿病性认知功能障碍患者学习记忆的改善作用
并与尼莫通作对照。方法:将45例符合诊断标准的患者随机分为电针组25例
对照组20例。电针组取四神聪、百会、风池、本神、内关为主穴
电针为疏密波
频率14
2
6次/min
强度326次/min
强度3
5
mA
每次治疗30 min
每日1次
连续5 d后休息2 d
共6周。对照组口服尼莫通
每次30 mg
每日3次
连续治疗6周。对两组治疗前后进行长谷川痴呆修改量表评分及韦氏记忆量表(WMS)评定。结果:两组疗效的差异具有显著性意义
电针组疗效优于对照组;治疗前两组WMS(总记忆商)无显著差异
P
>
0.05
治疗后电针组WMS评分明显上升
P
<
0.05
而对照组虽然也有上升
但不显著
P
>
0.05。电针组治疗后WMS在顺数、联想、触摸方面有显著上升
P
<
0.05;而对照组WMS在累加、触摸方面有显著上升
P
<
0.05;其余各项两组均表现为治疗前后差异不显著
P
>
0.05。结论:电针能改善糖尿病性认知功能障碍患者的认知功能和学习记忆能力。
Objective: To observe the effect of electroacupuncture(EA) on the learning and memory ability in diabetic cognitive dysfunction patients.Methods: Forty-five cases of diabetic mellitus(DM) patients with cognitive dysfunction were randomly divided into EA group(n=25) and medication group(n=20).For patients of EA group
main acupoints as Sishenchong(EX-HN 1)
Baihui(GV 20)
bilateral Fengchi(GB 20)
Benshen(GB 13) and Neiguan(PC 6) were punctured with filiform needles and stimulated electrically by setting the stimulating parameters being dense-sparse waves
frequency of 14-26 pulses/min
strength of 3-(5 mA) and duration of (30 min).The treatment was conducted once daily
5 times a week and continuously for 6 weeks.Patients of medication group were ordered to take Nimotop((30 mg)/time)
3 times everyday and continuously for 6 weeks.Modified Hastgawa Dementia Scale(HDS) and Wilson's Memory Scale(WMS) were used to evaluate the patients' cognitive function
memory ability and general conditions before and after the treatment.Results: After the treatment
according to HDS
of the 20 and 25 cases in medication and EA groups
1(5%) and 4(16%) experienced marked improvement
5(25%) and 15(60%) had moderate improvement
10(50%)and 5(20%) had mild improvement
and 4(20%) and 1(4%) had no improvement
with the total effective rates being 80% and 96% respectively.Rank test showed that the therapeutic effect of EA group was significantly superior to that of medication group(P<0.05) in improving patients' cognitive function.Self-comparison indicated that WMS of both groups increased significantly after the treatment(P<0.001
0.05)
including adding test of long-term memory and touching test of short-term memory in medication group
counting-down test of long-term memory
association test and touching test of short-term memory in EA group;and the effects of EA were apparently superior to those of medication in raising WMS(MQ)
counting-down test and association test(P<0.05
0.01).Conclusion: The therapeutic effect of EA is significantly superior to that of Nimotop in improving DM patients' cognitive function
learning and memory ability.
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