Objective: To observe the effect of electroacupuncture(EA) of "Shenmen"(HT 7) and "Zhizheng"(SI 7) on cardiac function and electrical activities of the cardiac sympathetic nerve in acute myocardial ischemia rabbits.Methods: Forty livid-blue rabbits were randomly divided into normal control

model

"Shenmen"(HT 7) and "Zhizheng"(SI 7) groups with 10 cases in each group.Acute myocardial ischemia(AMI) model was established by intravenous injection of pituitrin(3 U/kg).Changes of heart rate(HR)

maximum rising rate(+dp/dt max) and maximum descending rate(-dp/dt max) of the left ventricular systolic pressure(LVSP)

and discharges of cardiac sympathetic nerve(superior cardiac branch) were recorded.EA(2 Hz

5 V) was applied to bilateral "Shenmen"(HT 7) and "Zhizheng"(SI 7) for 30 min.Results: After AMI

HR

LVSP

+dp/dt max and firing frequency of cardiac sympathetic nerve decreased significantly(P<0.01)

and-dp/dt max increased obviously in model group(P<0.01).Compared with model group

HR

+dp/dt max and cardiac sympathetic discharge of HT7 and SI7 groups increased significantly 10 min and 20 min after EA(P<0.05

0.01)

and-dp/dt max of the later 2 groups reduced evidently 20 min after EA(P<0.05

0.01).No significant differences were found between HT7 and control groups in HR

LVSP and the firing frequency of cardiac nerve 20 min and 30 min after EA

and between SI7 and control groups in the firing frequency of cardiac nerve 30 min after EA(P>0.05).The effects of group HT7 were significantly better than those of SI7(P<0.05).Conclusion: EA of both HT7 and SI7 can obviously improve cardiac function and electrical activity of cardiac sympathetic nerve in AMI

and the effects of HT7 are markedly better than those of SI7.