WANG Hua, DENG Li-xia, WU Xu-ping, et al. Effect of Electroacupuncture of "Neiguan"(PC 6) on Heart Rate and Plasma Catecholamine Contents in Ventricular Tachycardia Rats[J]. Acupuncture research, 2009, 34(3): 180-182.
WANG Hua, DENG Li-xia, WU Xu-ping, et al. Effect of Electroacupuncture of "Neiguan"(PC 6) on Heart Rate and Plasma Catecholamine Contents in Ventricular Tachycardia Rats[J]. Acupuncture research, 2009, 34(3): 180-182.DOI:
Objective To observe the effect of electroacupuncture(EA) of "Neiguan"(PC 6) on heart rate(HR) and plasma catecholamine(CA) levels in ventricular tachycardia(VT) rats.Methods A total of 50 SD rats were randomly divided into normal control
sham-operation(sham)
model
EA-PC 6 and EA-LU 7 groups
with 10 cases in each.VT model was established by intravenous injection of cesium chloride(CsCl) via femoral vein.Electrocardiogram(ECG) was recorded.EA(2 Hz/15 Hz
1 mA) was separately applied to bilateral "Neiguan"(PC 6) and "Lieque"(LU 7) for 5 minutes
followed by collecting blood samples for detecting plasma norepinephrine(NE) and epinephrine(E) levels with fluorometric method.Results In comparison with normal control group
plasma NE and E contents in model group increased apparently(P<0.01).Compared with model group
HR and plasma NE and E contents of EA-PC 6 group reduced significantly(P<0.01)
while those of EA-LU 7 had no apparent change(P>0.05).Conclusion EA of "Neiguan"(PC 6) can downregulate heart rate and plasma CA level in VT rats
which may contribute to its effect in relieving tachycardia.