Objective To observe the effect of electroacupuncture(EA)of different acupoints on blood pressure(BP)

plasma angiotensin(Ang)Ⅱ

aldosterone(ALD)and atrial natriuretic peptide(ANP)of SHR

so as to observe the relative specificity of effects of acupoints.Methods A total of 60 SHR were randomly divided into model

Quchi(LI 11)

Zusanli(ST 36)

Shenmen(HT 7)

Jianyu(LI 15)and non-acupoint groups

with 10 cases in each.Other 10 Wistar rats were composed of normal group.EA(2 Hz

2 mA)was applied to LI 11

ST 36

HT 7

LI 15 and non-acupoint for 30 min

followed by measuring BP with BP-6 system.Plasma AngⅡ

ALD and ANP contents were assayed by radioimmunoassay.Results Compared with control group and pre-treatment

both systolic pressure(SP)and diastolic pressure(DP)of Quchi(LI 11)

Zusanli(ST 36)and Shenmen(HT 7)groups lowered significantly(P<0.05).No significant differences were found in the SP and DP of Jianyu(LI 15)and non-acupoint groups(P>0.05).After EA

the SP of Quchi(LI 11)and Shenmen(HT 7)groups were significantly lower than that of Jianyu(LI 15)and non-acupoint groups(P<0.05);and the DP of Quchi(LI 11)

Zusanli(ST 36)and Shenmen(HT 7)groups were markedly lower than that of Jianyu(LI 15)and non-acupoint groups(P<0.05).Compared with normal group

the contents of plasma AngⅡ and ANP of model group decreased significantly

and plasma ALD level of model group increased remarkably(P<0.05).Compared with model group

plasma AngⅡ levels in Quchi(LI 11)

Zusanli(ST 36)and Shenmen(HT 7)groups and ALD in Zusanli(ST 36)and Shenmen(HT 7)groups lowered significantly(P<0.05)

and plasma ANP content in Shenmen(HT 7)group increased obviously(P<0.05).Conclusion EA of LI 11

HT 7 and ST 36 can effectively lowered both DP and SP in SHR

which may be closely related to its effects in regulating the contents of AngⅡ

ALD and ANP.