The meridians and Zangfu-organs(viscera)are two major systems in the basic theory of traditional Chinese medicine(TCM).They were primarily emerged together in simple form possibly in the Han Dynasty shown by the unearthed silk manuscripts of Changsha Mawangdui Han Tomb

and became a systematic theory in classical book "Neijing"(The Yellow Emperor's Internal Classic).After classification of the meridians' disease manifestations described in book "Ling Shu-Jing Mai"(Miraculous Pivot:Meridians)we found that more than half of the manifestations appear along the running course of meridians.The symptoms and signs of disorders of the meridians correlated with viscera which have the same name in western medicine account for approximately 10%

and the rest pathologic manifestations correlated with the viscera in terms of TCM are approximately 30%.Current researches about meridian and viscera mainly focus on viscera

particularly on the stomach and heart.The researches on meridians and viscera that use real-time effects of acupuncture as indicators have a complicated relationship with the nerve segments

which presented as that"multiple meridians control one viscus"and the specificity of meridian.Our chronic experiment about blocking the meridians suggested an association between meridian and pathologic manifestations of viscera.Physical index measurement and mathematical analysis can verify certain patterns of meridian-physical appearances

which would be a direction for future meridian research.The stabilities of visceral functions rely on negative feedback regulation

which are probably realized by way of somatic and visceral afferent and efferent nerves and volume transmission of the tissue fluid channels of meridians.Therefore

signals of acupuncture stimulation of the distant acupoints might be transmitted to the central nervous system through neurohumor relay

open of the "negative feedback channels of meridians"

achieving a bidirectional regulation

and at the same time

producing aphenomenon of"sensation propagated along the meridian"during signal transmission.