Objective To observe the therapeutic effect of acupuncture in the treatment of patients with knee osteoarthritis(KOA)in the early stage.Methods A total of 60 KOA patients were randomized into medication group and acupuncture combined with medication(acupuncture)group(n=30 in each group).Patients of the medication group were treated by external application of Diclofenac Diethylamine Emulgel around the affected joint

3 times a day for 2 successive weeks and reasonable exercising training.Patients of the acupuncture group received routine medication and reasonable exercising training and acupuncture of Ashi-points

Zusanli(ST36)

Yanglingquan(GB34)

Yinlingquan(SP9)

Neixiyan(EX-LE4)and Dubi(ST35)at affected side with filiform needles which were manipulated with uniform reinforcing-reducing method for a while

followed by retaining the needles for 30 min.The treatment was conducted once every other day for 2 weeks.The pain degree was assessed by using visual analog scale(VAS)and the Western Ontario McMaster Universities Osteoarthritis Index(WOMAC)scale(0-240 points)was used to evaluate the severity of KOA

and the"Diagnosis of Syndromes of Traditional Chinese Medicine"was used to assess the therapeutic effect after the treatment.Results After the treatment

the VAS and WOMAC scores of both medication and acupuncture groups were significantly and respectively decreased in comparison with their own pre-treatment(P<0.05)

and the scores of the two indexes of the acupuncture group were evidently lower than those of the medication group(P<0.05).Of the two 30 cases in the medication and acupuncture groups

5(16.67%)and 6(20.00%)were cured

17(56.67%)and 19(63.33%)experienced marked improvement

6(20.00%)and 4(13.33%)were effective

2(6.67%)and 1(3.33%)were ineffective

with the effective rate of cure plus marked effectiveness being 73.33% and 83.33%

respectively.No significant difference was found between the two groups in the therapeutic effect(P>0.05).Conclusion Acupuncture combined with medication has a better therapeutic effect in the treatment of KOA in the early stage than that of the simple medication.