Objective To observe the effect of warming needling therapy on gastrointestinal reaction after hyperthermic intraperitoneal chemotherapy(HIPEC) in patients of spleen and stomach deficiency syndrome after colon cancer surgery. Methods A total of 120 cases of HIPEC were randomized into observation group and control group

60 cases in each. The patients of the two groups all received HIPEC. In the observation group

1 h before HIPEC

warming needling technique was applied to Zusanli(ST36)

Sanyinjiao(SP6) and Yinlingquan(SP9) and the even-needing technique of acupuncture was applied to Neiguan(PC6) for 30 min

and then the intravenous injection with Ondansetron was given 30 min before HIPEC. In the control group

The intravenous injection with Ondansetron was given 30 min before HIPEC. In the two groups

the changes in nausea

vomiting

abdominal distention

diarrhea

total bilirubin(TB)

alanine aminotransferase(ALT)

alkaline phosphatase(ALP) and KPS score

as well as the average hospitalization length of stay were observed. Results The total effective rates in the treatment of nausea

vomiting

abdominal distention and diarrhea were 91.67%(55/60)

93.33%(56/60)

80.00%(48/60) and 88.33%(53/60) in the observation group and were 78.33%(47/60)

78.33%(47/60)

63.33%(38/60) and 70.00%(42/60) in the control group respectively

and the total effective rate in the treatment of gastrointestinal reaction of HIPEC in the observation group was obviously higher than that in the control group(P<0.05). The KPS score and curative effect in the observation group was obviously higher than those of the control group(P<0.05)

and the average hospitalization length of stay in the observation group was obviously reduced as compared with the control group(P<0.05). There were no significant differences in serum TB

ALT and ALP contents between the two groups after treatment(P>0.05). Conclusion The warming needling technique of acupuncture and moxibustion alleviates the gastrointestinal reaction

improves KPS score and reduces the hospitalization length of stay in HIPEC patients after the surgery of colon cancer and differentiated as the spleen and stomach deficiency in traditional Chinese medicine.