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浙江中医药大学附属湖州中医院
纸质出版日期:2020
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张磊, 王娅玲, 傅瑞阳, 等. 隔姜灸预防肺癌化疗后恶心呕吐的随机对照研究[J]. 针刺研究, 2020,45(7):574-577.
ZHANG Lei, WANG Ya-ling, FU Rui-yang, et al. Ginger-partitioned moxibustion in the prevention of nausea and vomiting induced by chemotherapy in lung cancer:a randomized controlled trial[J]. Acupuncture research, 2020, 45(7): 574-577.
张磊, 王娅玲, 傅瑞阳, 等. 隔姜灸预防肺癌化疗后恶心呕吐的随机对照研究[J]. 针刺研究, 2020,45(7):574-577. DOI: 10.13702/j.1000-0607.190568.
ZHANG Lei, WANG Ya-ling, FU Rui-yang, et al. Ginger-partitioned moxibustion in the prevention of nausea and vomiting induced by chemotherapy in lung cancer:a randomized controlled trial[J]. Acupuncture research, 2020, 45(7): 574-577. DOI: 10.13702/j.1000-0607.190568.
目的:观察隔姜灸对肺癌化疗后胃肠道反应、生活质量、血小板及白细胞计数的影响。方法:将肺癌化疗患者随机分成对照组30例和观察组30例。对照组于化疗前1 h予欧必亭5 mg静脉缓慢注射;观察组在对照组的基础上于化疗后2 h取双侧足三里、内关、天枢及神阙行隔姜灸治疗
每次20 min。两种治疗均每天1次
共治疗3 d。观察两组患者化疗前2 d、化疗后24 h、化疗后7 d的消化道反应评级、生活质量评分
检测血小板及白细胞计数
观察两组的疗效和不良反应。结果:观察组化疗后24 h、7 d的消化道反应程度的有效率高于对照组(P<0.05);对照组和观察组化疗后24 h生活质量评分、白细胞、血小板计数均低于治疗前(P<0.05);化疗后7 d观察组的生活质量评分、白细胞、血小板计数高于对照组(P<0.05)
对照组的生活质量评分、白细胞、血小板计数均低于治疗前(P<0.05)。结论:隔姜灸预防肺癌化疗后恶心呕吐的临床疗效确切
操作简单
安全性高
无明显不良反应
患者依从性高。
Objective To observe the effect of ginger-partitioned moxibustion intervention on gastrointestinal reaction
the quality of life
the counts of blood platelet(PLT) and white blood cells(WBC) after chemotherapy in lung cancer patients. Methods The lung cancer patients treated with chemotherapy were randomized into observation group(30 cases) and control group(30 cases). In the control group
the intravenous injection with Tropisetron(5 mg) was given 1 h before chemotherapy. In the observation group
in addition to the same treatment as the control group
2 hours after chemotherapy
ginger-partitioned moxibustion was applied to bilateral Zusanli(ST36)
bilateral Neiguan(PC6) and bilateral Tianshu(ST25) for 20 min each time. The treatments were conducted once daily for 3 days. Separately
2 days before chemotherapy
24 h and 7 days after chemotherapy
the gastrointestinal reaction score and the score of the quality of life
the PLT and WBC counts were observed in the two groups. Results The effective rate of the gastrointestinal reaction degree in the observation group were higher than those in the control group 24 h and 7 days after chemotherapy(P<0.05). Twenty-four hours after chemotherapy
the score of the quality of life
the PLT and WBC counts were lower as compared with those before the treatment in both groups respectively(P<0.05). Seven days after chemotherapy
the score of the quality of life
the PLT and WBC counts in the observation group were higher than those in the control group(P<0.05). Conclusion The ginger-partitioned moxibustion achieves the definite clinical effect of the prevention of nausea and vomiting induced by chemotherapy in lung cancer. This therapy is simple in operation
high in safety
absent in obvious adverse reactions and high in patient's compliance.
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