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1. 首都医科大学附属北京儿童医院中医科
2. 河北省唐山市妇幼保健院中医科
3. 首都医科大学附属北京中医医院治未病中心
纸质出版日期:2020
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尤圣杰, 孙映雪, 郭菲宇, 等. 针刺联合西药治疗儿童脾胃湿热型腹型过敏性紫癜的临床疗效及安全性评价[J]. 针刺研究, 2020,45(8):671-675.
YOU Sheng-jie, SUN Ying-xue, GUO Fei-yu, et al. Clinical efficacy and safety of acupuncture combined with western medicine in treatment of children with abdominal Henoch-Schonlein purpura with spleen-stomach damp-heat syndrome[J]. Acupuncture research, 2020, 45(8): 671-675.
尤圣杰, 孙映雪, 郭菲宇, 等. 针刺联合西药治疗儿童脾胃湿热型腹型过敏性紫癜的临床疗效及安全性评价[J]. 针刺研究, 2020,45(8):671-675. DOI: 10.13702/j.1000-0607.190649.
YOU Sheng-jie, SUN Ying-xue, GUO Fei-yu, et al. Clinical efficacy and safety of acupuncture combined with western medicine in treatment of children with abdominal Henoch-Schonlein purpura with spleen-stomach damp-heat syndrome[J]. Acupuncture research, 2020, 45(8): 671-675. DOI: 10.13702/j.1000-0607.190649.
目的:观察针刺联合西药治疗儿童腹型过敏性紫癜脾胃湿热证的临床疗效。方法:将60例腹型过敏性紫癜脾胃湿热证患儿随机分为对照组30例和治疗组30例。对照组给予氢化泼尼松2 mg·kg
(-1)
·d(-1)·d
(-1)
;治疗组在对照组的基础上联合针刺天枢、内关、足三里、中脘、气海、三阴交
留针15 min
每日1次。两组均治疗7 d。治疗前后对腹痛、便血、呕血、纳呆、腹胀、皮肤紫癜、大便潜血及腹部B超进行评分
观察两组患儿腹痛消失时间
判定临床疗效。结果:治疗组总有效率为96.7%(29/30)
对照组为80.0%(24/30)
治疗组高于对照组(P
<
0.05)。两组治疗后腹痛、便血、呕血、纳呆、腹胀、皮肤紫癜、大便潜血及肠壁肿胀评分及总积分均较本组治疗前降低(P
<
0.05)
且治疗后治疗组腹痛、纳呆、腹胀、肠壁肿胀评分及总积分均低于对照组(P
<
0.05)。治疗组腹痛消失时间早于对照组(P
<
0.05)。结论:针刺联合西药治疗腹型过敏性紫癜脾胃湿热证临床疗效优于单纯西药治疗
可明显改善临床症状、体征
缩短腹痛消失时间。Objective To investigate the clinical effect of acupuncture combined with western medicine in the treatment of children with abdominal Henoch-Schonlein purpura with spleen-stomach damp-heat syndrome. Methods A total of 60 children with abdominal Henoch-Schonlein purpura with spleen-stomach damp-heat syndrome were randomly divided into treatment group and control group
with 30 patients in each group. The patients in the control group were given Hydroprednisone 2 mg·kg(-1);治疗组在对照组的基础上联合针刺天枢、内关、足三里、中脘、气海、三阴交
留针15 min
每日1次。两组均治疗7 d。治疗前后对腹痛、便血、呕血、纳呆、腹胀、皮肤紫癜、大便潜血及腹部B超进行评分
观察两组患儿腹痛消失时间
判定临床疗效。结果:治疗组总有效率为96.7%(29/30)
对照组为80.0%(24/30)
治疗组高于对照组(P
<
0.05)。两组治疗后腹痛、便血、呕血、纳呆、腹胀、皮肤紫癜、大便潜血及肠壁肿胀评分及总积分均较本组治疗前降低(P
<
0.05)
且治疗后治疗组腹痛、纳呆、腹胀、肠壁肿胀评分及总积分均低于对照组(P
<
0.05)。治疗组腹痛消失时间早于对照组(P
<
0.05)。结论:针刺联合西药治疗腹型过敏性紫癜脾胃湿热证临床疗效优于单纯西药治疗
可明显改善临床症状、体征
缩短腹痛消失时间。
Objective To investigate the clinical effect of acupuncture combined with western medicine in the treatment of children with abdominal Henoch-Schonlein purpura with spleen-stomach damp-heat syndrome. Methods A total of 60 children with abdominal Henoch-Schonlein purpura with spleen-stomach damp-heat syndrome were randomly divided into treatment group and control group
with 30 patients in each group. The patients in the control group were given Hydroprednisone 2 mg·kg
(-1)
·d(-1)·d
(-1)
and in addition to the treatment in the control group
those in the treatment group were given acupuncture at Tianshu(ST25)
Neiguan(PC6)
Zusanli(ST36)
Zhongwan(CV12)
Qihai(CV6)
and Sanyinjiao(SP6) once a day
with a needle retaining time of 15 minutes. Both groups were treated for 7 days. The scores of abdominal pain
hematochezia
hematemesis
vomiting
poor appetite
abdominal distension
purpura
occult blood in stool
and abdominal ultrasound were determined before and after treatment
and the time to the disappearance of abdominal pain was observed. Clinical outcome was evaluated. Results The treatment group had a significantly higher effective rate than the control group [96.7%(29/30) vs 80.0%(24/30)
P
<
0.05]. Both groups had significant reductions in the scores of abdominal pain
hematochezia
hematemesis
poor appetite
abdominal distension
purpura
occult blood and abdominal ultrasound and the total score after treatment(P
<
0.05)
and compared with the control group after treatment
the treatment group had significantly lower scores of abdominal pain
poor appetite
abdominal distension
and abdominal ultrasound and total score(P
<
0.05). The treatment group had a significantly shorter time to disappea-rance of abdominal pain than the control group(P
<
0.05). Conclusion Acupuncture combined with western medicine has a better clinical effect than western medicine alone in the treatment of abdominal Henoch-Schonlein purpura with spleen-stomach damp-heat syndrome and can significantly improve clinical symptoms and signs and shorten the time to disappearance of abdominal pain.
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