Effect of Moxibustion Combined with Immunomodulator on Expression of c-erbB-2 mRNA[J]. Acupuncture research, 2000, (1): 43-45. DOI: 10.13702/j.1000-0607.2000.01.010.
进而降低基因表达水平有关Molecular biological mechanism of the action of moxibustion combined with immunomodulator was investigated
using the mice which were subcutaneously transplanted with H 22 (Haptoma) cell line as a solid carcinoma model. The result showed that c erbB 2 mRNA expression level was obviously reduced in tumor tissue in moxibustion group and group moxibustion and immunomodulator combination(group M+IM)
as compared with tumor control group. The result implied that inhibition of tumor cell proliferation by moxibustion and immunomodulator combination was related to the reduction of c erbB 2 mRNA through decreasing rates of c erbB 2 gene transcription.