Indirect Moxibustion on Hypoxic Tumor Cells and Immunological Function of Tumor Undergoing Radiotherapy[J]. Acupuncture research, 2000, (1): 46-50. DOI: 10.13702/j.1000-0607.2000.01.011.
隔药饼灸对乏氧肿瘤细胞及肿瘤放疗免疫系统的影响
摘要
采用隔药饼灸结合1 37CSγ射线放疗对实体瘤 (HAC)小鼠进行研究
不同时间肿瘤体积及瘤重抑制率表明
艾灸能增强对乏氧肿瘤细胞的杀伤作用。小鼠荷瘤后NK、LAK、IL 6活性及IL 2含量均明显降低
放疗后除NK活性外
均进一步降低
经艾灸治疗可以明显提高NK、LAK及IL 6活性和IL 2含量
其中LAK活性达到正常水平。提示隔药饼灸可促进肿瘤放疗后免疫系统损伤的恢复This article studies the effect of indirect moxibustion on HAC tumor bearing mice treated with radiotherapy. The results of hypoxic tumor regeneration after irradiation showed that combination of the indirect moxibustion and radiotherapy had the coordinating efficiency of antitumor effect. The NK activity
LAK activity
IL 2 content and IL 6 activity of tumor bearing mice were all significantly depressed. All the above parameters were further depressed after irradiation except for NK activity. Indirect moxibustion could promote all the parameters in different degrees
and LAK activity reached the normal level. The results showed that indirect moxibustion's influence on IL 6 activity and IL 2 content can promote NK activity