Effect of Acupuncture on Cholinergic Central Nervous System in Rat of Alzheimer Disease[J]. Acupuncture research, 2000, (3): 175-178. DOI: 10.13702/j.1000-0607.2000.03.003.
To explore the effect of acupuncture on cholinergic central nervous system in rat of Alzheimer disease as well as the way how to create the effect. Methods: Divided rats into three groups of the normal group
AD group and the acupuncture group. Observed respectively the behavior alteration of rats before and after acupuncture
and observed the change of senile plaques (SPs) and neurofibrillary tangles (NFT) in cerebral cortex and hippocampus by special staining for SPs. Results: The rats of acupuncture group were found the behavior had better improvement and the SPs number was decreased
but NFT hadn't evidently changed. Conclusion: Acupuncture can improve rat's function of cholinergic central nervous system.