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1. 广州中医药大学第一附属医院眼科
2. 广州中医药大学第一临床医学院
3. 广东省干部疗养院
4. 广州中医药大学第一附属医院针推康复中心
纸质出版日期:2021
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刘红, 滕月, 俞晓艺, 等. 岭南火针联合0.1%玻璃酸钠滴眼液治疗干眼症的随机对照研究[J]. 针刺研究, 2021,46(10):863-868.
LIU Hong, TENG Yue, YU Xiao-yi, et al. Lingnan fire needling combined with 0.1% sodium hyaluronate eye drops in the treatment of xerophthalmia: a randomized controlled trial[J]. Acupuncture research, 2021, 46(10): 863-868.
刘红, 滕月, 俞晓艺, 等. 岭南火针联合0.1%玻璃酸钠滴眼液治疗干眼症的随机对照研究[J]. 针刺研究, 2021,46(10):863-868. DOI: 10.13702/j.1000-0607.200960.
LIU Hong, TENG Yue, YU Xiao-yi, et al. Lingnan fire needling combined with 0.1% sodium hyaluronate eye drops in the treatment of xerophthalmia: a randomized controlled trial[J]. Acupuncture research, 2021, 46(10): 863-868. DOI: 10.13702/j.1000-0607.200960.
目的:评价岭南火针联合人工泪液治疗干眼症的临床疗效。方法:将86例干眼症患者随机分为治疗组和对照组
每组43例。对照组双眼滴用0.1%玻璃酸钠滴眼液
双眼每次各1滴
每日3次
连续治疗4周。治疗组在对照组基础上给予岭南火针治疗
取双侧少泽、内承泣、泪小点旁
每周治疗1次
连续治疗4周。治疗前后评价临床疗效及视力、眼压、眼部症状评分、眼表疾病指数(OSDI)评分、眼表荧光染色(FL)评分、泪膜破裂时间(BUT)、泪液分泌量(SchimerⅠ)的变化
以及使用Keratograph眼表综合分析仪评价治疗前后泪河高度、眼红指数的变化。结果:与本组治疗前比较
两组治疗后双眼眼部症状评分、OSDI评分、FL评分、眼红指数均降低(P<0.05)
BUT均升高(P<0.05);治疗组泪河高度较治疗前升高(P<0.05)。治疗后与对照组比较
治疗组双眼眼部症状评分、OSDI评分、眼红指数均降低(P<0.05)
BUT、泪河高度均升高(P<0.05)。对照组有效率为76.74%(66/86)
治疗组有效率为84.88%(73/86)
治疗组临床疗效高于对照组(P<0.05)。结论:岭南火针联合0.1%玻璃酸钠滴眼液可有效治疗干眼症
在改善干眼症状评分、OSDI评分、BUT、泪河高度、眼红指数等方面优于单纯玻璃酸钠滴眼液。
Objective To observe the effect of Lingnan fire needling combined with artificial tears in the treatment of xerophthalmia. Methods A total of 86 xerophthalmia patients were equally and randomly divided into treatment group and control group. The patients of both groups were received treatment with 0.1% sodium hyaluronate eye drops in their eyes 3 times a day
one drop in each eye. In addition
the patients of treatment group also treated by Lingnan fire needling on bilateral Shaoze(SI1)
Neichengqi and beside lacrimal puncta once a week. The treatment was conducted for 4 consecutive weeks. Before and after 4 weeks of treatment
the clinical efficacy
visual acuity
intraocular pressure
ocular symptom score
OSDI score
fluorescence staining(FL) score
schemer I
tear menisci height
tear film break-up time(BUT) and eye redness index were recorded and evaluated. Results After the treatment
self-comparison showed that the symptom score
OSDI score
FL score and eye redness index were significantly decreased(P<0.05)
and BUT was notably increased in both groups(P<0.05) in comparison with their own pre-treatment. The tear menisci height in the treatment group was higher than that before the treatment(P<0.05). Comparison between the two groups showed that the symptom score
OSDI score and eye redness index were obviously lower in the treatment group than in the control group(P<0.05)
whereas the BUT and tear menisci height were evidently higher(P<0.05). The total effective rate of the treatment group was 84.88%(73/86)
better than 76.74%(66/86) of the control group(P<0.05). Conclusion Lingnan fire needling combined with 0.1% sodium hyaluronate eye drops is more effective than simple sodium hyaluronate eye drops for xerophthalmia patients
with significant curative effect and no adverse reactions.
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