Objective To determine the graded-disease-spectrum of the nervous system of acu-moxibustion treatment based on its clinical efficacy.Methods We carried out a cross-sectional academic sample investigation on the graded-disease-spectrum of acu-moxibustion by collecting and analyzing data from the self-administered questionnaires which were completed by professional persons who have high-ranking professional titles(associate chief physicians and chief physicians) and are majoring in acupuncture and moxibustion.Then

the collected experts' opinions were analyzed by fuzzy comprehensive estimation technique and statistical processing.Results A total of 58 medical conditions involving 4 grades and 126 subtypes were included and analyzed.The Grade Ⅰ contains 14 subtypes as Bell's palsy(in the acute stage and convalescence stage)

primary sciatic neuralgia

migraine(mild type and moderate type)

etc.which can be relieved by using acu-moxibustion therapy only.The Grade Ⅱ contains 53 subtypes

such as transient cerebral ischemic attack

acute cerebrovascular disease(in the convalescence stage and sequelae stage)

chronic Bell's palsy(sequelae)

Hunt's facial palsy

etc.which can be relieved by using acu-moxibustion as the main therapy.The Grade Ⅲ contains 22 subtypes

such as acute stage of ischemic cerebrovascular disease(with coma and without coma)

acute stage of hemorrhagic ischemic cerebrovascular disease(with coma and without coma)

etc.which may be relieved to a certain degree by using acu-moxibustion as the supplementary or main therapy.The Grade Ⅳ contains 37 subtypes

such as Wohlfart-Kugelberg-Welander disease

myasthenia gravis(type Ⅲand type Ⅳ)

myasthenia gravis of medicinal herbs resource

chorea major

etc.whose clinical effects are not known if treated with acu-moxibustion.Conclusion Acu-moxibustion therapy has apparent advantages in the treatment of different clinical conditions of the nervous system.