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1. 暨南大学
2. 广州中医药大学
3. 佛山市南海区第三医院
纸质出版日期:2013
移动端阅览
张毅敏, 陈爱连, 唐纯志, 等. 电针对重型颅脑损伤昏迷患者促醒作用的临床观察[J]. 针刺研究, 2013,38(2):158-162.
ZHANG Yi-Min, CHEN Ai-Lian, Tang Chun-zhi1, et al. Clinical Observation on Electroacupuncture for Arousing Consciousness of Comatose Patients with Severe Trauma Brain Injury[J]. Acupuncture research, 2013, 38(2): 158-162.
张毅敏, 陈爱连, 唐纯志, 等. 电针对重型颅脑损伤昏迷患者促醒作用的临床观察[J]. 针刺研究, 2013,38(2):158-162. DOI: 10.13702/j.1000-0607.2013.02.017.
ZHANG Yi-Min, CHEN Ai-Lian, Tang Chun-zhi1, et al. Clinical Observation on Electroacupuncture for Arousing Consciousness of Comatose Patients with Severe Trauma Brain Injury[J]. Acupuncture research, 2013, 38(2): 158-162. DOI: 10.13702/j.1000-0607.2013.02.017.
目的:观察电针对重型颅脑损伤昏迷患者的促醒作用。方法:90例重型颅脑外伤患者随机分为对照组、电针组及纳络酮组
各30例。对照组予常规西医治疗;纳络酮组在常规西医治疗基础上加静脉滴注纳络酮;电针组在常规西医治疗基础上加用电针治疗
针刺百会、水沟、风府透哑门、合谷和涌泉
疏密波
频率1Hz/50Hz
强度1~4mA。各组治疗均每天1次
共治疗14d。观察各组患者在治疗前后及治疗结束后1个月的格拉斯哥昏迷评分(GCS)变化
比较各组患者在治疗结束后1个月格拉斯哥预后分级(GOS)及清醒率。结果:各组患者治疗后的GCS评分较治疗前均明显改善(P<0.05)
且治疗结束1个月的GCS评分较治疗结束时继续提高(P<0.05)。纳络酮组及电针组在治疗结束及结束后1个月的GCS评分及GOS分级都明显优于对照组(均P<0.05)
电针组与纳络酮组之间比较差异无统计学意义(P>0.05)。治疗结束后1个月
电针组及纳络酮组清醒率均优于对照组(P<0.05)
电针组与纳络酮组之间差异无统计学意义(P>0.05)。结论:早期电针干预可提高重型颅脑损伤患者的GCS评分、GOS分级及清醒率
促进神经功能的恢复
对重型颅脑损伤昏迷患者具有促醒及改善预后的作用。
Objective To observe the arousal effect of electroacupuncture(EA) stimulation of Baihui(GV 20)
Shuigou(GV 26)
etc.on severe craniocerebral injury patients.Methods A total of 90 cases of severe craniocerebral injury were randomly allocated to routine medication
naloxone and EA groups
with 30 cases in each group.For patients of the routine medication group
mild hypothermia therapy
medicines for dehydration
hormonal therapy
vascular dilation
cerebral nutrition suppor-ting
anti-inflammation
etc.were given.For patients of the naloxone group
intravenous drip of naloxone 0.4 mg/kg in the first 3 days
0.2 mg/kg for 7 days and 0.1 mg/kg afterwards.For patients of the EA group
EA(1 Hz/50 Hz) was given for 30 min once daily.All the treatments were conducted once a day for 14 days.The Glasgow Coma Scale(GCS) and Glasgow Outcome Scale(GOS) were used for assessing the therapeutic effect.Results In comparison with pre-treatment in each one of the routine medication
naloxone and EA groups
GCS scores were all obviously increased in the 3 groups following the treatment
and one month's follow-up(P<0.05).The GCS scores of both naloxone and EA groups were significantly higher than those of the routine medication group(P<0.05).No significant difference was found between the naloxone group and EA group in GCS scores(P>0.05).According to the GOS
one month's follow-up showed that of the three 30 cases in the routine medication
naloxone and EA groups
6
12 and 14 were improved
8
10 and 10 moderate handicap
8
3 and 2 severe handicap
5
3 and 2 vegetative state
and 3
2 and 2 dead
with the arousal rates being 46.66%
73.33% and 80.00%
respectively.The therapeutic effects of both naloxone and EA groups were significantly superior to those of the routine medication group(P<0.05).Conclusion EA intervention at early stage can promote the recovery of neurological function
accelerate the consciousness from coma and improve the outcomes of patients with severe traumatic brain injury.
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