The regulative effect of acu-moxibustion on functional activities of the body involves a complex network.Acupoints

the sensors and amplifiers of acupuncture and moxibustion stimulation signals

play an important role in triggering the coo-perative performance of the complex network system.The authors of the present paper make a comprehensive discussion about the interrelationship of the nervous structure

mast cells

calcium ion

relevant chemical substances(SP

histamine

5-HT

ATP

endogenous opioid peptides

etc.)

different key nodal joints of the regulative networks for acu-moxibustion intervention

trying to interpret the underlying mechanism of acu-moxibustion as a whole.