Bioinformatics analysis of the molecular network regulation is the main content of systems biology

may reveal the complex life phenomena from interactions among molecules and will bring about a far-reaching impact on our current understanding about life activities of organism.MicroRNAs(functional RNAs)can regulate mRNA transcription through inhibition of posttranscriptional protein-coding gene expression

target degradation

etc.

and are extensively involved in various biological processes in the cells.It is generally held that the therapeutic effect of acu-moxibustion intervention involves multi-channels

multitargets

and multi-levels of both peripheral and central nervous systems of the body but has not been fully revealed

being similar with functional forms of molecular regulatory networks.Thus

it is necessary to introduce new ideas and methods for studying the underlying mechanism of acu-moxibustion therapy.The molecular regulatory networks of microRNA would provide a new way for revealing the mechanism of acu-moxibustion interventions.