Objective To observe the therapeutic effect of electroacupuncture(EA)stimulation of"Daimai"(GB 26)on metabolic syndrome in rats.Methods SD rats were randomly divided into blank control group(n=9)

model group(n=9)and EA group(n=9).The metabolic syndrome model was established by feeding the rats with high fat and sugar forage(containing 20%lard

10%cane sugar

10% defatted milk powder

2% cholest

3% yolk powder and 55% normal forage)for 12weeks.EA(2Hz/100Hz

1-2mA)was applied to bilateral"Daimai"(GB 26)for 20min

once daily for 4weeks.Fasting blood glucose(FBG)

serum triglyceride(TG)

total cholesterol(TC)

high density lipoprotein-cholesterol(HDL-C)

lower density lipoprotein-cholesterol(LDL-C)contents were detected using chemical methods

fasting serum insulin(FINS)was determined by using radioimmunoassay.Homeostasis model assessment-index of resistance(HOMA-IR

insulin resistance index=FBG×FINS/22.5)was calculated.Results Compared to the blank control group

the body weight(from the 8th week on)

abdominal circumference(from the 4th week on)

and FBG

FINS

TG

TC

LDL-C contents as well as HOMA-IR in the model group were significantly increased(P<0.05

P<0.01)

while the HDL-C content was considerably lowered after modeling(P<0.05).In comparison with the model group

the body weight on the 16th week

FBG

FINS

HOMA-IR

TG

TC and LDL-C levels were evidently down-regulated in the EA group(P<0.05

P<0.01).No significant differences were found between the model and EA groups in the abdominal circumference and HDL-C content(P>0.05).Conclusion Electroacupuncture stimulation of"Daimai"(GB 26)can reduce insulin resistance

regulate blood lipid

and lower blood glucose in metabolic syndrome rats.