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1. 黑龙江中医药大学附属第二医院针灸科二病房
2. 黑龙江中医药大学针灸推拿学院
纸质出版日期:2015
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孙远征, 宋晶. 针刺配合立普妥治疗脾虚食滞型原发性高脂血症疗效观察[J]. 针刺研究, 2015,40(1):61-64.
SUN Yuan-zheng, SONG Jing. Clinical Trials for Treatment of Primary Hyperlipidemia by Using Acupuncture in Combination with Lipitor[J]. Acupuncture research, 2015, 40(1): 61-64.
孙远征, 宋晶. 针刺配合立普妥治疗脾虚食滞型原发性高脂血症疗效观察[J]. 针刺研究, 2015,40(1):61-64. DOI: 10.13702/j.1000-0607.2015.01.012.
SUN Yuan-zheng, SONG Jing. Clinical Trials for Treatment of Primary Hyperlipidemia by Using Acupuncture in Combination with Lipitor[J]. Acupuncture research, 2015, 40(1): 61-64. DOI: 10.13702/j.1000-0607.2015.01.012.
目的:评价针刺配合立普妥治疗脾虚食滞型原发性高脂血症的临床疗效。方法:将60例脾虚食滞型原发性高脂血症患者随机分为针药组30例和西药组30例。针药组取百会、中脘及双侧足三里、三阴交、阴陵泉、丰隆穴
每日治疗2次
每次40min
并配合口服立普妥20mg
每日1次
共治疗6周。西药组仅口服立普妥。观察患者治疗前后血清中甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)含量并评定疗效。结果:两组治疗后血清中TC、TG较治疗前均明显改善(P<0.05)
针药组血清LDL-C、HDL-C较治疗前明显改善(P<0.05)
针药组治疗后血清中TC、TG、LDLC、HDL-C较西药组治疗后明显改善(P<0.05)。针药组的总有效率为93.3%(28/30)
明显高于西药组的73.3%(22/30
P<0.05)。结论:针刺配合立普妥治疗原发性高脂血症有一定疗效
优于单纯口服西药立普妥。
Objective To observe the clinical effect of acupuncture therapy combined with Lipitor in the treatment of primary hyperlipidemia(spleen deficiency and food stagnation type).Methods Sixty primary hyperlipidemia patients(spleen deficiency and food stagnation type)were equally randomized into medication group and acupuncture plus medication group.Patients of both groups were treated by oral administration of Lipitor(20mg/tablet
one tablet per day)for 6weeks.Manual acupuncture stimulation was applied to Baihui(GV 20)
Zhongwan(CV 12)
and bilateral Zusanli(ST 36)
Sanyinjiao(SP 6)
Yinlingquan(SP 9)and Fenglong(ST 40)for 40 min
twice daily for 6weeks except the weekends.Serum total cholesterol(TC)
triglyceride(TG)
high density lipoprotein-cholesterol(HDL-C)
low density lipoprotein-cholesterol(LDL-C)were detected by using a full-automatic biochemistry analyzer before and after the treatment.The therapeutic effect was assessed according to the standards described in"Guide Principles for Clinical Researches of New Chinese Herbal Drugs".Results After the treatment
the levels of serum TC
TG of the two groups were significantly decreased in comparison with pre-treatment in the same one group(P<0.05)
and the therapeutic effect of the acupuncture+medication group was significantly superior to that of simple medication group in lowering serum TC
TG and LDL-C levels and heightening HDL-C levels(P<0.05).Of the two 30 cases in the medication and acupuncture+medication groups
2(6.7%)and 7(23.3%)were basically controlled in their blood-lipid levels
10(33.3%)and 15(50.0%)had a marked improvement
10(33.3%)and 6(20.0%)were improved
and 8(26.7%)and 2(6.7%)were invalid
with the effective rates being 73.3% and 93.3%
respectively.Conclusion Acupuncture combined with administration of Lipitor is effective in improving primary hyperlipidemia in patients
which is superior to administration of simple Lipitor.
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