Long-lasting hypertension results in ventricular remodeling characteristic of myocardial hypertrophy including myocyte hypertrophy and myocardial fibrosis
apathological process failed to be blocked by the current biomedical means and could eventually lead to heart failure.It has been shown that acupuncture can excite the parasympathetic nerve to counter the overtonic activity of sympathetic nerve
elicit antihypertensive effect and produce cardioprotection via the regulation of calcium signaling-related proteins in myocytes
suggesting its potential role in the management of these disorders.In this paper
the authors review relevant studies and propose
with respect to the autonomic nerve
endocrine system
cytokines and intracellular calcium signaling pathways
several novel ideas concerning the treatment of hypertensive myocardial hypertrophy and cardiac malfunction by acupuncture.