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1. 广州中医药大学第一临床医学院
2. 广州中医药大学第一附属医院
3. 广州中医药大学基础医学院
纸质出版日期:2016
移动端阅览
黄超原, 卢洋, 孙术宁, 等. 热敏灸治疗腰椎间盘突出症疗效与安全性的Meta分析[J]. 针刺研究, 2016,41(3):255-264.
HUANG Chao-yuan, LU Yang, SUN Shu-ning, et al. Clinical Efficacy and Safety of Heat-sensitive Moxibustion Therapy for Lumbar Disc Herniation:A Meta-analysis[J]. Acupuncture research, 2016, 41(3): 255-264.
黄超原, 卢洋, 孙术宁, 等. 热敏灸治疗腰椎间盘突出症疗效与安全性的Meta分析[J]. 针刺研究, 2016,41(3):255-264. DOI: 10.13702/j.1000-0607.2016.03.013.
HUANG Chao-yuan, LU Yang, SUN Shu-ning, et al. Clinical Efficacy and Safety of Heat-sensitive Moxibustion Therapy for Lumbar Disc Herniation:A Meta-analysis[J]. Acupuncture research, 2016, 41(3): 255-264. DOI: 10.13702/j.1000-0607.2016.03.013.
目的:评价热敏灸治疗腰椎间盘突出症的临床疗效与安全性。方法:计算机检索PubMed、EMBase、Cochrane图书馆、中国生物医学文摘数据库、中国期刊全文数据库、中文科技期刊数据库和万方数据库
收集关于热敏灸治疗腰椎间盘突出症的随机对照试验(RCT)
对符合纳入标准的临床研究进行资料提取和质量评价后
采用RevMan 5.3统计软件进行Meta分析。结果:最终纳入20项RCT
合计1 861例患者。Meta分析结果显示:试验组的总有效率高于对照组[RR=1.13
95%CI(1.09
1.18)
P<0.001];改良日本骨关节学会(M-JOA)评分优于对照组[MD=-3.17
95%CI(-3.88
-2.47)
P<0.001];M-JOA各亚项评分差值也均优于对照组:日常生活能力前后差值[MD=1.04
95%CI(0.44
1.64)
P<0.001]
主观症状前后差值[MD=0.58
95%CI(0.23
0.92)
P=0.001]
客观症状前后差值[MD=1.12
95%CI(0.58
1.65)
P<0.001];视觉模拟评分低于对照组[MD=-1.17
95%CI(-1.78
-0.57)
P<0.001];复发率低于对照组[RR=0.54
95%CI(0.37
0.80)
P=0.002];两组均报道无不良反应事件。敏感性分析显示纳入的文献同质性较强且结果稳定
但漏斗图分析显示纳入文献可能存在发表偏倚。结论:热敏灸治疗腰椎间盘突出症具有一定的疗效
且较安全。
Objective To systematically review the effectiveness and safety of heat-sensitive moxibustion(HSM)therapy in the treatment of lumbar disc herniation(LDH).Methods Papers of randomized clinical trials(RCTs)concerning the effectiveness and safety of HSM therapy for LDH published in both Chinese and English before November 17
2015 were collected from PubMed
EMBase
Cochrane library
CNKI
CBM
WanFang Data and VIP databases according to the inclusion and exclusion criteria and by using key words of"thermal moxibustion""heat-sensitive acupoint""lumbar intervertebral disc herniation(LIDH)""lumbar disc herniation(LDH)"and "lumbago backache"
followed by screening
data extracting and methodological quality assessing.Then
the Meta-analysis was performed using RevMan 5.3software.Results Twenty RCTs were included eventually
containing a total of 1 861 cases treated by HSM therapy in the treatment of LDH patients.The Meta-analysis shows that the effectiveness and safety of HSM therapy for LDH are superior to those of other therapies
which is drawn from total effective rate of treatment group[RR=1.13
95%CI(1.09
1.18)
P<0.001]
M-JOA score[MD=-3.17
95%CI(-3.88
-2.47)
P<0.001]
M-JOA score difference of various subgroups:daily life ability effect difference [MD=1.04
95%CI(0.44
1.64)
P<0.001]
subjective effect symptoms difference[MD=0.58
95%CI(0.23
0.92)
P=0.001]
objective effect symptoms difference[MD=1.12
95%CI(0.58
1.65)
P<0.001]
VAS score [MD=-1.17
95%CI(-1.78
-0.57)
P<0.001]
the recurrence rate[RR=0.54
95%CI(0.37
0.80)
P=0.002]
and no adverse reactions mentioned in the reported results.The sensitivity analysis showed a greater homogeneity in literature and the results were stable
but funnel plot analysis showed a publication bias.Conclusion The HSM therapy is effective and safe in the treatment of LDH patients.
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