Myocardial cell apoptosis is very common in the clinic

and is caused by myocardial ischemia reperfusion injury(MIRI).There are different degrees of cell apoptosis in MIRI.However

initiation of the signal transduction mechanism of myocardial cell apoptosis is unclear.The present research confirmed that acupuncture and moxibustion are effective interventions for cell apoptosis in MIRI through three approaches:the death receptor pathway

mitochondrial pathway and endoplasmic reticulum pathway.In this paper

the authors summarize the mechanism characteristics of acupuncture and moxibustion in MIRI cell apoptosis

and discuss the signal transduction pathways involved in the effects of acupuncture and moxibustion in MIRI cell apoptosis

in order to provide new ideas and evidence for the clinical application of acupuncture and moxibustion to prevent cell apoptosis in MIRI.