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1. 河南中医药大学康复医学院
2. 河南中医药大学第一附属医院康复中心
纸质出版日期:2022
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李冰, 张朝霞, 冯晓东, 等. 眼针对不完全性脊髓损伤患者体感诱发电位及运动诱发电位的影响[J]. 针刺研究, 2022,47(4):329-335.
LI Bing, ZHANG Zhao-xia, FENG Xiao-dong, et al. Effects of eye acupuncture on motor evoked potential and somatosensory evoked potential in patients with incomplete spinal cord injury based on neuroelectrophysiological technology[J]. Acupuncture research, 2022, 47(4): 329-335.
李冰, 张朝霞, 冯晓东, 等. 眼针对不完全性脊髓损伤患者体感诱发电位及运动诱发电位的影响[J]. 针刺研究, 2022,47(4):329-335. DOI: 10.13702/j.1000-0607.20210196.
LI Bing, ZHANG Zhao-xia, FENG Xiao-dong, et al. Effects of eye acupuncture on motor evoked potential and somatosensory evoked potential in patients with incomplete spinal cord injury based on neuroelectrophysiological technology[J]. Acupuncture research, 2022, 47(4): 329-335. DOI: 10.13702/j.1000-0607.20210196.
目的:观察眼针对不完全性脊髓损伤(SCI)患者体感诱发电位(SEP)、运动诱发电位(MEP)的影响,评价其临床疗效。方法:根据随机数字表法将90例不完全性SCI患者随机分为运动治疗组、眼针组、联合治疗组,每组30例。运动治疗组给予常规运动治疗和作业治疗,30 min/次;眼针组取双侧上焦区、下焦区、肝区和肾区进行眼针治疗,20 min/次;联合治疗组给予运动治疗组和眼针治疗组相同的治疗方法。3组治疗均为1次/d
7 d为1个疗程,共治疗4个疗程。按照美国脊髓损伤协会分级标准评定各组患者脊髓损伤分级、临床疗效及运动功能、感觉功能,用改良的Barthel指数(MBI)评分评价其日常生活活动能力,用ViKing Quest型肌电诱发电位仪测定其SEP和MEP潜伏期。结果:运动治疗组总有效率为56.7%(17/30)
眼针组总有效率为66.7%(20/30)
联合治疗组总有效率为90.0%(27/30)
联合治疗组总有效率高于运动治疗组和眼针组(P<0.05)。与本组治疗前比较,治疗后3组患者的运动功能、轻触觉和针刺觉评分均升高(P<0.05)
运动治疗组和联合治疗组MBI评分升高(P<0.05)
3组患者SEP的N11、N20、N23、P38和MEP的皮质手区、C7棘突旁(Csp)、皮质腿区、腰(L)4—L5棘突旁(Lsp)潜伏期均缩短(P<0.05)。治疗后与运动治疗组比较,眼针组运动功能评分升高(P<0.05)
MBI评分降低(P<0.05)
MEP的皮质手区、Csp、皮质腿区、Lsp潜伏期均缩短(P<0.05)。治疗后与运动治疗组、眼针组比较,联合治疗组运动功能、轻触觉、针刺觉及MBI评分均升高(P<0.05)
SEP的N11、N20、N23、P38及MEP的皮质手区、Csp、皮质腿区、Lsp潜伏期均缩短(P<0.05)。结论:眼针联合运动治疗可明显提高不完全性SCI患者脊髓和大脑皮层运动和感觉神经传导的兴奋性,可有效促进患者运动和感觉功能恢复,提高日常生活活动能力。
Objective To observe the effects of eye acupuncture on motor evoked potential(MEP) and somatosensory evoked potential(SEP) in the patients with incomplete spinal cord injury so as to evaluate its clinical efficacy. Methods According to the random number table
90 patients were divided into exercise therapy group
eye acupuncture group and eye acupuncture combined exercise therapy group(combined treatment group)
30 cases in each. In the exercise therapy group
patients were treated with the routine exercise and occupational therapy. Patients of the eye acupuncture group were treated with eye acupuncture at upper jiao region
lower jiao region
liver region and kidney region bilaterally. Patients of the combined treatment group were given the routine exercise and occupational therapy combined with eye acupuncture. All the treatments were conducted once daily
7 days as one treatment course for 4 treatment courses. Before treatment and 4 weeks after treatment
the motor function
light touch sensation and pinprick sensation
injury grade and clinical efficacy were assessed separately
using the criteria developed by the American Spinal Injury Association. The modified Barthel index(MBI) was adopted to evaluate the activities of daily livings. By monitoring SEP and MEP
the neurophysiological conditions were assessed for spinal cord injury. Results The total effective rate was 56.7%(17/30)
66.7%(20/30) and 90.0%(27/30) in the exercise therapy group
the eye acupuncture group and the combined treatment group
respectively. The total effective rate in the combined treatment group was higher than those in the other two groups(P<0.05). Compared with those before treatment
the scores of motor function
light tough sensation and pinprick sensation were all increased after treatment in three groups(P<0.05)
MBI score was increased in both the exercise therapy group and the combined treatment group(P<0.05)
and the latency of SEP(N11
N20
N23
P38) and the Cortical(hand region)
Csp
Cortical(leg region) and Lsp of MEP were all shortened in the three groups separately(P<0.05). After treatment
compared with the exercise therapy group
the score of motor function was increased(P<0.05)
MBI score decreased(P<0.05) and MEP latency shortened(P<0.05) in the eye acupuncture group. After treatment
compared with the exercise therapy group and the eye acupuncture group
the scores of motor function
light touch sensation and pinprick sensation
as well as MBI score were all increased(P<0.05)
and the latency of SEP(N11
N20
N23
P38) and MEP shortened(P<0.05) in the combined treatment group. Conclusion In treatment of incomplete spinal cord injury
eye acupuncture combined with exercise therapy can significantly increase the excitability of sensory and motor nerve conduction in the spinal cord and cerebral cortex of patients
effectively promote the recovery of patients' motor and sensory function and improve the activities of daily living.
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