Objective To evaluate the efficacy and safety of moxibustion at Baihui(CV20) combined with acupuncture in treatment of cervical vertigo. Methods From the databases

such as CNKI

VIP

WanFang

CBM

PubMed

Cochrane Library and Embase

the studies of randomized controlled trials(RCTs) on moxibustion at CV20 combined with acupuncture for cervical vertigo were searched from inception to September 15

(th)

2021. The Cochrane risk of bias assessment tool was utilized to evaluate the quality of the included literature. Using RevMan5.3

Stata12.0 and TSA0.9.5.0 10 Beta software

the Meta-analysis and trial sequential analysis(TSA) were performed. Results Seventeen RCTs with 1 232 patients were included. Meta-analysis showed that in the trial group(moxibustion at CV20 combined with acupuncture)

the total effective rate(RR=1.17

95%CI[1.12

1.22]

P

<

0.000 1)

the curative and remarkably-effective rate(RR=1.28

95%CI[1.20

1.36]

P

<

0.000 1) and the score of cervical vertigo(WMD=2.88

95%CI[1.87

3.89]

P

<

0.000 1) were all better when compared with the control group(simple acupuncture or electroacupuncture group). The results of trial sequential analysis indicated that for the cumulative Z-score of each RCT

the Z-curve crossed the conventional test boundary and TSA boundary

which further confirmed the clinical efficacy of moxibustion at CV20 combined with acupuncture on cervical vertigo. Conclusion The clinical efficacy of moxibustion at CV20 combined with acupuncture is determined in treatment of cervical vertigo.