Objective To explore the effect of transcutaneous electrical acupoint stimulation(TEAS) combined with auricular acupressure on serum sexual hormone level

and the ovarian

follicular and uterine development in the girls with precocious puberty. Methods Sixty girls with precocious puberty were randomly divided into a control group(30 cases

2 cases dropped off) and a treatment group(30 cases

3 cases dropped off). In both the control group and the treatment group

the healthy life-style intervention was provided for 12 weeks. Besides

in the treatment group

TEAS was delivered for 20 minutes each time

twice a week; and bilateral auricular acupressure was combined. The duration of treatment was 12 weeks. The levels of serum luteinizing hormone(LH)

follicle stimulating hormone(FSH) and estradiol(E_2)

as well as ovarian volume

maximum follicular diameter and uterine volume before and after treatment were detected

and the safety was evaluated separately. Results Compared with before treatment

the contents of serum LH and FSH were increased(P<0.05)

and the ovarian volume and the maximum follicle diameter were increased(P<0.05) in the control group after treatment; the contents of serum FSH and E_2 were decresed(P<0.05)

and the maximum follicular diameter was reduced significantly(P<0.05) in the treatment group after treatment. Compared with the control group

the contents of serum LH

FSH and E_2 were decreased(P<0.05)

while the ovarian volume and the maximum follicle diameter were decreased(P<0.05) in the treatment group after treatment. Conclusion TEAS combined with auricular acupressure can effectively decrease the level of sex hormone

improve the ovarian and uterine development and retard the gonadal development. Such combined therapy is of high safety and conductive to regulating the development for the girls with precocious puberty.