For more than half a century

the modern bioresearch in acupuncture has made remarkable advancements

proving scientific basis underlying the traditional

intuitive treatment

as well as leading to some new discoveries with the potential to enhance the effectiveness of acupuncture as we know it. Meanwhile

the clinical researches have started to shift its paradigm from traditional individual observation to modern evidence-based medicine. However

there is little interaction between basic and clinic researches

which are like two separate worlds

not benefiting each other. Also the education and training of acupuncture are still traditional style

little combining with modern studies. To bridging the large gap

we need translational science involving in. In this article

with a critical reviews of the limitations of the traditional methods of acupuncture

the challenges faced by clinic practices and placebo-control studies

and the advantages and disadvantages of basic research

we propose a methodological paradigm of the translational research

Translational Acupuncture Research Spectrum

that meets the current situation of acupuncture researches

hoping to give insights into this field and to promote modern acupuncture to move towards a new stage.