最新刊期
1982年第2期
- 摘要：脑新肽是从人脑中分离得到的一个阿片样四肽,它有很强的镇痛作用,它不但存在于人脑中,也存在于兔脑中。针刺镇痛时,家兔中央灰质中脑新肽的释放增加,痛阈亦增加。针刺前中央灰质灌流中脑新肽的含量为5.8±0.4毫微摩/毫升;针刺30分钟后,灌流液中的含量为10.6±0.9毫微摩/毫升;平均增加4.8±0.6毫微摩/毫升。说明针刺镇痛与脑新肽的释放有关。针刺镇痛时,家兔脑脊液中脑新肽的含量,随着针刺时间的延长而增加,痛阈亦随着针刺时间的延长而升高。835|0|0更新时间：2023-08-11
- 摘要：祖国医学将人体视为一整体,认为经络联系着体表与内脏。有“十二经脉者,内属于脏腑,外络于肢节”的记载,这种体表与内脏相联系的观点是临床诊断的依据,也是祖国医学理论重要的组成部分,研究这种联系不仅具有十分重要的理论意义,而且也是临床实践的需要. 近年来临床不断出现这方面报道,内脏患病时,病人体表出现所谓过敏点、结节、丘疹922|86|0更新时间：2023-08-11
- 摘要：The ancient medical science of our country looks upon a human body as a monolithic whole. According to this "concept of th.e whole" the exterior(body surface)of a human body is correlated with its viscera(internal organs)through the proper channels and collaterals. There are records of such findings as the twelve channels linking with the viscera in-640|11|0更新时间：2023-08-11
- 摘要：针麻下阑尾切除术我院已积累了2,000余例临床资料,取得了一些关于如何提高针麻阑尾切除术效果的粗浅体会。1979年选择了针麻和腰麻阑尾切除术各200例对照,通过术中、术后观察随访,进一步肯定针麻阑尾切除术的效果和适应症的选择。分析如下: 资料分析针麻阑尾切除术200例中男80例,女120例,年龄最小10岁,最大78岁。急性单纯型This paper reports a comparison of the results of each 200 csaes of appendectomy under acupuncture anesthesia and lumbar anesthesia respec- tively. We have performed appendectomy in more than 2000 cases under acupuncture anesthesia, from which we selected 200 cases to compare with the same number of cases with similar clinical picture and severity of disease. Observation on the operative procedure and follow-up examiniation further proved that acupuncture anesthesia gave satisfactory results for appendectomy. Excellent results were obtained in 83.5% of cases, successful results in 95.5%, comparable to that in 96.5% cases under lumbar anesthesia. The incidence of adverse reactions such as nausea, vomiting, lowering of blood pressure, bradycardia and contraction of abdominal viscera was significantly lower in acupuncture anesthesia group than in lumbar anesthesia group. But in completeness in the control of pain with acupuncture anesthesia is a problem. In order to overcome this unpleasant situation, in addition to the proper selection of acupuncture points and appropriate manipulation of needles, we used 1-2 ml 2% lidocaine locally, which often lessen ed the pain satisfactorily. This indicates that the use of acupuncture in combi nation with drug is a good method which will enhance the effective ness of anesthesia on one hand and lessen the incidence of adverse reaction thus making the operation more safe on the other. Complications were less and milder, and recovery was faster in patients of acupuncture anesthesia group than in the lumbar anesthesia group. The patients in the former group usually did not need fluid infusion and dolantin in infusion after operation. From the above data we considr that acupuncture has an analgesic property and is able to enhance the immunity of human body resulting in a recovery of its normal function. The combination of acupuncture and drug is a good anesthetic mathod for appendectomy.594|0|0更新时间：2023-08-11
- 摘要：近年来有的学者提出针药复合针刺麻醉,也就是针麻与药麻相结合的一种麻醉方法.因而研究针麻、药麻各对机体功能活动的影响,就成为一个主要课题了。因此,我们在临床中分别观察了针麻、药麻(连续硬膜外麻醉)术中患者的心率、血压变化情况,并作了分析. 方法对象为70例腹部手术患者,其中40例针麻为一组,30例药麻为另一组,两组均系Thirty cases of abdominal operation under acupuncture anesthesia and 40 cases of abdominal operation under cpidural anesthesia the changes in the blood pressure and the heart rate in the course of operation were determined and analysed. 1. The heart rate and the. blood pressure of the patients in abdominal operation under acupuncture anesthesia showed a tendency to increase. whileincision of the abdomen, exploration and operation on viscera were being performed, the blood pressure and the heart rate showed statistically significant increase as compared with that before acupuncture anesthesia (P<0.01). The heart rate and the blood pressure of the patients in abdominal operation under drug anesthesia showed a tendency to decrease. Particularly while exploration and operation on viscera were being performed, the blood pressure and the heart rate showed statistically significant decrease(P<0.0l). These results indicated that effects of acupuncture anesthesia and drug anesthesia on the blood pressure and the heart rate are completely contrary to each other. 2. We found that in operation under acupuncture anesthesia, the more the heart rate an.d the blood pressure of patients increase, the more the effects decrease. In operation under drug anesthesia the case is reversed. 3. Through discussion we believe that the combination of acupuncture anesthesia with drug anesthesia might produce interferential and resistant effects to each other.682|0|0更新时间：2023-08-11
- 摘要：针麻胃大部切除术在我院已做过1.185例,但是这一麻醉方法还不能适应所有胃手术的需要.因为它还存在镇痛不全、内脏牵拉反应,肌松不满意等问题。所以胃切除术使用针麻,对病例还得经过一定的挑选。比较理想条件是病人痛阈高,耐针力好,意志较坚强,体形消瘦,胃体较大,病灶较单纯,中医辨证上属阳虚型等.然而临床上理想病例是不多的,这样胃切除术针麻效果就受到一定的限制.In this report, there are altogether 97 cases of gastrectomy including the combined anesthesia group, 25 cases, acupuncture anesthesia group, 36 cases; epidural anesthesia group, 36 cases Comparison of the three groups during operation. 1. Comparison of the dosage of lignocaine used in the combined anesthesia with that in the epidural anesthesia. The average dose of lignocaine administered in the combined anesthesia was 204.3mg. while that in the epidural anesthesia was 514. 2mg. the difference being statistically significant. Comparison of the dosage of lignocaine administered in a certain unit of time (in minutes) between the two. In the former the dose was 1.15mg/min, while in the latter 2.79mg/min,The differnce is also statistically significant. 2. Blood pressure and pulse rate were the objective data of physiological and pathological response to an operation. The preoperative B.P. and pulse rate were taken as the standard values. Range of decrease in these values from the beginning of operation to 1.5 hrs after operation was taken for comparison. We discovered that in comparison of the three groups there are statistically significant difference of decrease in diastolic pressure and systolic pressure. In comparison between acupuncture anesthesia and the combined anesthesia,there were no statistical significance. While in comparison of acupuncture and the combined anesthesia with epidural anesthesia respectively, the differences are statistically very significant: 3. Comparison of postoperative elctromyogram of the combined anesthesia with that of acupuncture anesthesia and epidural anesthesia. The postoperative electromyogram of the rectus muscle is the objective index of incisional pain. We observed and recorded the myoelectricity continuously for three hours after operation ( the average accumulated voltage of myoelectricity). Statistically the difference of the three was not very significant. However we divided the durational records into two equal parts(i. e. 1. 5hrs. each). After analysis, we found that the voltage of myoelectricity in acupuncture anesthesia was obviously minimized in the latter 1.5 hrs. in comparison with the fprmer 1,5 hrs, The fact was also true for the combined925|0|0更新时间：2023-08-11
- 摘要：舒乐安定(Surazepine)是一种新型的安定剂,属于苯骈二氮杂(艹卓)类(benzodiazepine)的衍生物,具有较强的镇静、安眠抗惊,抗焦虑作用。在国外作为手术前夜的睡眠药应用于临床,取得了较好的效果。在国内由北京医学院药学系和湖北制药厂试制成功,由湖北药厂提供使用。我们于1981年1月将本剂作为针麻木前用药应用于临床,以期提高针麻效果,并进行了脑电观察和测痛试验,以观察其镇静作用及其对皮肤痛阈Surazepine,one of the benzodiazepines,is a new weak sedative providing effects of sadationsleep, anticonvulsion and anxiolytic action. It was used as premedication under careful observation during acupuncture anesthesia and tried in normal persons. The presence of wave and 25-28 times/second waves in EEG was noticed after administration of this drug. The effect varies with the dosage and individual. It can strengthen analgesic effect of acupuncture anesthesia especially together with Fentanyl. Surazepine was used in one hundred and forty patients as premedication with 2mg, 3mg, or 4mg one hour preoperatively with satisfactory effect in 85%. The side effect are nausea, vomiting and weakness ( 10.7%) but all were not severe and disappeared spontaneously. For sedation 3mg seems better. Surazepine can reduce nervousness and fear. Patient's BP and pulse rate were stable and analgesic effect of acupuncture anesthesia was improved. It is a good drug for premedication under acupuncture anesthesia.748|0|0更新时间：2023-08-11
- 摘要：据报道,头针疗法对于神经系统疾病的疗效很突出,并在脑电图的研究中发现头针“对皮层功能的调节作用和病理状态的恢复作用”。作者还口头报道有“头针波”的发现。在医疗实践中,我们也观察到头针治疗的某些疗效。本工作首先试图验证上述脑电图研究报道的可靠性,以便进一步深入研究。825|0|0更新时间：2023-08-11
- 摘要：我们过去的工作曾揭示:电针镇痛时,小鼠脑内某些核团的突触后膜有明显的增厚现象。由于化学突触的后膜是神经递质受体所在部位,这种显著的增厚现象引起了我们的重视。为了进一步验证其厚度变化的规律性,我们再一次测定了针刺镇痛所引起的丘脑束旁核,中脑中缝背核和中脑中央灰质等部位突触后膜(包括突触后电子致密物质,并一律测量最宽处)的厚度变化。实验动物仍为正常健康的成年小白鼠,雌雄兼The present article reports the results on the evident increase of thickness of the postsynaptic membrane in some nuclei of the mice brain during acupuncture analgesia. The investigated regions of the mice brain are thalamus parafascicularis nucleus, mid-brain dorsal raphe and mid-brain grey matter. The thickness of the postsynaptic membrane in these regions was measured on the electron micrograph by the micrometer of the light microscope. The obtained data show that the differences between acupuncture analgesia group and control group are marked, the former being larger than the latter. It is suggested that the changes in synaptic ultrastructure during the acupuncture analgesia are regarded as a reflection of the unity between structure and function in the central nervous system. Because the postsynaptic membrane is the site of the neurotransmitter's receptors in action, it is possible that the mechanism of synaptic chemical transmission is morphologically reflected in the significant thickening of postsynaptic membrane in some brain regions which take part in the process of acupuncture analgesia.860|0|0更新时间：2023-08-11
- 摘要：多巴胺(DA)是重要的单胺类神经递质,脑内DA能神经系统与许多方面的脑机能状态密切相关,如情绪、精神病及锥体外运动等等。已有的实验资料证明针刺可激发脑内DA能系统,使DA及其代谢产物高香草酸在脑内含量明显升高。但脑内DA能系统机能对针刺镇痛的影响如何,有着不同的看法。无关、对抗和协同三种意见都有。本实验利用DA受体激动剂阿扑吗啡(Apomorphine)和DA受体拮抗剂The present paper deals with the effects which were induced by injection into lateral ventricle with apomorphine, agonist of DA-receptor or haloperidol, antagonist of DA-receptor during electrical acupuncture analgesia in mice. The results show that the effects of electrical acupuncture analgesia will increase approximately twice after apomorphine is injected. The effects of electrical acupuncture analgesia were almost abolished by haloperidol. It suggests that the dopaminergic system participated in and enhanced the effects of electrical acupuncture analgesia. Based on the previous experiments and the present one, we think that there is a synergic effect between the brain dopaminergic system and the electrical acupuncture analgesia. In addition, we assume that DA path of mesencephalonlimbic system might play an important role in the electrical acupuncture analgesia.1027|0|0更新时间：2023-08-11
- 摘要：许多工作证明,作为第二信使的环核苷酸可能参与了痛觉的调节机制。我们曾经观察了电针镇痛时大鼠全脑及各脑区环-磷酸腺苷(cAMP)环-磷酸鸟苷(cGMP)含量的变化。发现电针镇痛时端脑cAMP含量下降,而脑干部位cGMP明显升高,这些变化可被阿片受体阻断剂纳洛酮所翻转。反复电针时,电针镇痛作用会逐渐下降发生Groups of rats were decapitated after 30 min electroacupuncture (EA) on bilateral Zusanli-Sanyinjiao points. The analgesic effect of EA was expressed by the percent change of the tail flick latency, and the brain cAMP and cGMP content measured by protein binding and radio-immunoassay respectively. EA stimulation for 30 min (one session) caused a significant increase in tail flick latency. In the meantime there was a significant decrease of cAMP content (-23%, p<0.05) in telencephalon, as well as a decrease of cGMP in diencephalon(-25%, p<0.05) and an increase of cGMP(+43%, p<0.05)in lower brain stem. Repeated EA stimulation for 6 sessions, with 30 min 'intervening between successive sessions, resulted in a gradual decrease and final disappearance of its analgesic effect, which was termed "EA tolerance". Cyclic nucleotides measurement revealed that in EA tolerant rat the cAMP content of the telencephalon remained in a low level as was in EA analgesic rats. However, the characteristic changes in cGMP content found in EA analgesic rats were no longer existing in EA tolerant rat. The most impressive increase in cGMP content in the lower brain stem was completely abolished. That the inability to raise cGMP content in lower brain stem may be partially responsible for the development of EA tolerance was supported by the fact that the effect of EA analgesia could be partially restored by intracerebroventricular injection of 100μg of cGMP, a dose which by itself was not analgesic. The results indicate that an insufficient supply of cGMP during repeated or prolonged EA stimulation may constitute one of the mechanisms for the diminution of the analgesic effect during EA tolerance.958|0|0更新时间：2023-08-11
- 摘要：为了研究电针镇痛过程中脑内乙酰胆碱(ACh)代谢的动态变化规律,本文将用更新率的研究方法,从电针镇痛过程中脑内ACh含量的变化,电针对脑内ACh合成率的影响和电针对ACh利用率的影响等三个方面作一探讨。一、电针镇痛过程中脑内ACh含量的变化In order to further evaluate the role of central cholinergic nerves in acupuncture analgesia, the effect of acupuncture on the content and turnover rate of central ACh in rats was examined in the present study. The pain threshold after 30 minutes' electroacupuncture in rats (14) (0.110 mA) is significantly higher than that in the control rats (14) (0.044mA ) (P<0.01); and the ACh content in brain of the electroacupuncture group is also obviously elevated, i.e. in caudate nucleus, 2.022 to 2.455 r/g (P<0.05), and hypothalamus, 1.572 to 1.927r/g.Hemicholine and eserine were used as tools to block the synthesis and the degradation of ACh respectively for the purpose of the assessment of the utilizing and synthesizing rate of ACh. It was found that during acupuncture analgesia the utilization rate of ACh was significantly accelerated in brain of rats(103); in caudate nucleus the rate increased in electroacupuncture group twice in the control, and in hypothalamus, it is also nearly doubled. In addition, the rate of synthesis was also in high speed ( rats 63). Present studies of turn over rate indicated that in central nervous system the elevation of ACh content by electroacupuncture results from the new kinetics balance between the increased rates of ACh utilization and synthesis. In combination with reports available on this subject it may be suggested that the increase of utilization rate present an evidence that ACh may play an important role in electroacupuncture analgesia.962|0|0更新时间：2023-08-11
- 摘要：我们在以往工作中观察到针刺体表穴位的传入信息及内脏伤害信息均投射到延脑内侧网状巨细胞核,并发生会聚,两种信号相互作用的结果,多数情况下表现为伤害性反应受到压抑。实验结果表明延脑网状巨细胞核参与针刺抑制內脏痛过程中的整合作用。为了进一步了解针刺诱导对该核团神经元机能状态的影响,及其与针刺镇痛的关In order to determine the effect of acupuncture on the neuronal excitability in RGC and its relation to acupuncture analgesia, a Ichronic microelectrode method was used to study the change of neuronal discharge by acupuncture in RGC. In 48 out of 52 neurones,the change of spontaneous firing rate induced by acupuncture was significant. The change of firing rate manifested mainly in three patterns; 1). a decrease in firing rate (by 50-90%), 19 neurones; 2 ). an increase in firng rate ( up to 500%), 10 neurones; 3 ) an increase followed by a decrease in firing rate about 3 minutes later, 10 neurones. Most of the above neurones accept not only visceral nociceptive signals but also acupuncture signals. It might be considered as the neurological foundation of integration in acupuncture analgesia. It is supposed that the decrease of the neuronal excitability is helpful to depress the transmission of nociceptive information to higher centre. Most neurones with the increase of spontaneous firing rate were located in ventral part of RGC. It is inferred that RGC may take part not only in integration but also in modulation in acupuncture analgesia.930|0|0更新时间：2023-08-11
- 摘要：以往我们曾在胃大部切除术病人术前、术中记录了病人指(趾)血管容积脉搏波幅的变化.在动物实验中记录了电刺激内脏大神经时腹肌肌电反应,证明了这两项生理指标对探讨內脏疼痛反应的规律和评定临床腹部手术的针麻效果上具有一定价值.本文利用胃牵拉反应的动物模型记录了腹肌The responses of the stomach traction involving the augmentation of the abdominal EMG, the increase of the efferent bursts of the recurrent laryngeal nerve and the diminution in amplitude of the volume pulse wave of the ear were partly inhibited by acupuncture. From the observation it is suggested that the impulses arising from the stomach traction are conveyed not only in the great splanchnic and vagus nerves, but also by way of the abdominal somatic nerves, which innervate the parietal peritoneum. The pulling response was more prominent from par pylorica than other portions of the stomach. It could be decreased obviously when the stomach was tracted outside of the abdominal cavity or the parietal peritoneum anaesthetized locally with procaine. It is therefore concluded that diminishing the stimulation on the parietal peritoneum as less as possible is very important for a good acupuncture anaesthesia in abdominal surgery.666|0|0更新时间：2023-08-11
- 摘要：近年来,国內许多单位通过临床治疗和对大量人群的调查,对循经感传现象进行了广泛的观察和研究,肯定了循经感传现象的客观存在。但它的本质目前还不清楚,存在着不同的看法。曾经有人观察列,有个别感传显著的受试者,当电针机的音响与针刺穴位引起的循经感传结合数次之后,单独给以电针The objective of this study is to observe the possibility of elaborating a conditioned reflex on the basis of propagated sensation along channels (PSC).Eleven subjects with marked PSC were observed. A rhythmic sound was used as neutral stimulus which was reinforced by PSC arisen from stimulating Hegu or Waiguan. The results of total 40 experiments revealed that the conditioned reflex could not be established under the circumstances. Galvanic skin response (GSR) was recorded simultaneously in 4 cases among them. The feature of GSR also showed that conditioned reflex had never been established yet. In a special case, EMG from preauricular region was used as a responsive indication of PSC. Therefore, the results of the experiments could be evaluated by EMG records objectively. However, no sign of formation of conditioned reflex appeared. The facts mentioned above suggest that the conditioned reflex could scarcely be established on the basis of PSC.699|0|0更新时间：2023-08-11
- 摘要：以前工作表明,无论正常人和患者,几乎人人都可被查出与我国古典经脉循行线相符合的信息传导轨迹,称为隐性循经感传线(LPSC)。LPSC的一个重要的特征是它具有高度的定位性。根据这一特征,我们已经查出这条线的全程都有较其两侧皮肤阻抗为低的特性。本文应用二种皮肤电位测试仪,测定了大肠经的LPSC线上和线内外皮肤电位的差别。1356|0|0更新时间：2023-08-11
- 摘要：狗在深麻下,经膀胱输尿管孔插入和敏感的光电染料扩散装置相连的导管,并与八道记录仪相连,用以准确测量尿排出量,同时测量血压、中心静脉压和心率.静脉注射10mg速尿引起持续性多尿,针刺涌泉穴可抑制对侧的多尿,此效应又为针刺肾俞穴和给酚妥拉明(a-阻断剂)所阻断。在涌泉穴注射95%酒精和石碳酸也产生类似针刺该穴的作用。针刺第772|24|0更新时间：2023-08-11
- 摘要：针刺治疗86例高脂血症,男41,女45,年龄31～72岁,其中69例为原发性高脂血症,17例继发于糖尿病.针刺治疗前,病人食用营养和代谢病中心为高脂血症病人推荐的特殊饮食至少一年,针刺治疗前对每个病人检查血总脂,胆固醇和甘油三酸酯,所用穴位为:脾—胰4和6(SP4和6),肝8(L1V8),血管区_(12)(CV—12)单用针刺激时同时扎以上穴位824|60|0更新时间：2023-08-11
- 摘要：头针配合马丹阳天星十二二穴治疗15例中风和40例多发性脑脊髓硬化引起的瘫痪,效果较单用天星十二穴好,且开始恢复快。球后视神经炎、膀胱控制困难,阵发性无力、阳萎等各种慢性神经性疾病,也都迅速获得改善,有时甚至在头几次治疗即见效。857|49|0更新时间：2023-08-11
- 摘要：将人乳房晕皮肤和蛙抱雌疣(Clasping pad of frog)置入4%甲醛—1%氯化钙液中冷固定24小时,冰冻切片50微米,用Wachstin-Meisel介绍的三磷酸腺苷酶组织化学方法染色,相邻切片以GrosBielachwsky氏银法作为对比染色。发现这些区域富于“固有丛”,在三磷酸腺苜酶组化法处理后,着色很深,而非“固有丛”的其他结构染色淡.如经733|19|0更新时间：2023-08-11
- 摘要：针刺治疗18例皮肤,骨骼、肌肉、呼吸和心血管系统等全身性疾病经过各种治疗而无效的病人,疾病包括慢性酒精中毒、扰郁症、灼痛,慢性口腔唇部泡疹,带状泡疹、头皮湿疹、慢性颈关节炎,髋关节炎、网球肘、慢性气管炎,鼻息肉、高血压、心律不齐伴有皮下水肿等。在不同疾病中所用穴位和针刺的时间不同.治疗效果为优、良和好转.701|39|0更新时间：2023-08-11
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