最新刊期

    1982年第3期
    • 电针镇痛的耐受及其与吗啡的交叉耐受

      韩济生
      1982(3): 163-173.
      摘要:在大鼠和家兔实验中我们发现,经过连续数小时的电针刺激,电针的镇痛作用逐渐减弱而趋于消失,即对电针的镇痛作用发生耐受。电针耐受的动物吗啡的镇痛作用也减弱。反之,由于多次注射吗啡而发生吗啡耐受的动物,电针的镇痛效果也明显降低。这种双向性的交叉耐受说明电针镇痛与吗啡镇痛的机理有相似之处。对电针耐受的机理进行研究的结果表明,在电针初期,中枢5-羟色胺、内啡素和脊髓内的去甲肾上腺素大量释放,引起镇痛效果;持继数小时后这种作用逐渐发生耐受,镇痛效果减弱。与此同时,中枢神经系统中对抗镇痛的物质(脑内的去甲肾上腺素以及内原性抗阿片物质等)又大量生成。在这双重作用下,针效遂趋减弱。对电针镇痛耐受的进一步研究,有可能为提高临床针刺镇痛效果提供新的线索。  
        
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    • 头针治疗临床初步观察

      黄坤厚, 冯秀娥
      1982(3): 175-177.
      摘要:据报导,头针治疗总的有效率达91.4%,对脑源性疾病的治疗有效率达97.4%。比体针效果更好。本工作在治疗神经系统疾病的过程中,观察了头针疗法和体针治疗的临床效果,试图寻找更好的针刺治疗方法。方法对32例以脑血管病为主的神经系统疾病患者作了649次的头针治疗观察,并对7例The present work was carried out on 32 patients with nervous dise- ases, receiving head-acupuncture 649 times and on 7 patients receiving body-acupuncture as a control. The immediate effect after the first head- acupuncture and the final curative effect were used as a basis for evalua- tion. The first head-acupuncture had some instantaneous effect on brain angiopathy and myo-asthenia grave, effective rate of 44%. The effect of head-acupuncture treatment was related to some factors. In patients with brain angiopathy of young age and short course of disease, the effect was good but not better than the effect of body-acupuncture. Head-acupunc- ture combined with body-acupuncture would seem to increase the effect of treatment.  
        
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    • 成柏华, 潘翠琴, 鲍延熙, 陆惠华, 俞国瑞, 郑道声
      1982(3): 178-182.
      摘要:针刺治疗心脏病最早见诸于风湿性心脏办膜病,根据报导堪称良效、而后治于冠心病心绞痛,在国内也屡见报道亦获良效。本文为探求针刺对急性心肌梗塞的疗效,于1978~1980年对14例急性心肌梗塞针刺双侧内关穴,于针前、针后止痛疗效、左心室功能(STI)、血浆cAMP含量、心电图∑ST等项目的观察上亦获一定疗效,今分析小结如下:Fourteen coronary patients with acute myocardial infarction were trea- ted with manual acupuncture at Neiquan points bilaterally. In thirteen cases the angina pectoris was relieved or alleviated after acupuncture (One patient had had no angina pectoris). The relief or alleviation of angina pectoris is therofore 100%. Eight of the cases (80%) showed a signi- ficant decrease in plasma cAMp concentration after acupuncture, the mean value of decrease being 11.01 pmole/ml (p<0.05 in single sided limit). In 2 cases the plasma cAMp level roso, but one of these patients had car- diogenic shock and the other died. The STI in 10 of 14 cases shortened after acupuncture: in 3 cases it remained unchanged and in 1 case it in- creased. The shortened cases amounted to 71.4% and the mean interval of shortening was-0.034 (p<0.01). The value of ∑ST segment in the ECG in 5 of 6 cases was decreased after acupuncture, the percentage being 83.3% and the mean value of decrease was 5.1 mm(p<0.05). According to the data presented above, we presume that the relief of angina pectoris in acupuncture therapy at Neiquan points might be connec- ted to the release of endorphine and the decrease of cAMp in the plasma might be due to the effect of acupuncture in changing the concentration of the catecholamines. These effects of acupuncture may be useful in the prognosis of myocardial infarction. The decrease of ∑ST indicates an im- provement in myocardial ischemia, while the shortening of STIs also po- ints to the improvement on cardiac function. From these preliminary obs- ervations, it may be concluded that acupuncture at Neiguan points pro- duces a favorable effect in the treatment of acute myocardial infarction. Further studies are in progress.  
        
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    • 针麻下施行后颅凹手术临床分析

      王宗学, 徐屏南, 王梦敏, 杨亚平, 洪江林
      1982(3): 183-185.
      摘要:一般资料本院在针麻下施行前颅凹手术、颞顶枕区手术的基础上开展了针麻下施行后颅凹手术。本文观察了60例后颇凹手术,其中男性31例,女性29例,有工人、农民、干部、学生,以农民为多。年龄最大的58岁,最小的16岁,以青壮年为多。其病种有听神经瘤、颅底凹陷症、小脑半球肿瘤、三叉神经痛、第Ⅳ脑室肿瘤等以听神经瘤为多。  
        
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    • 针麻刺激频率对甲状腺手术效果的影响

      张哲元
      1982(3): 188-191.
      摘要:目前针麻刺激频率尚无统一见解,为了比较同一组穴位不同的刺激频率对针麻效果的影响,我们于1982年3月以前对150例针麻甲状腺手木患者,均采用合谷、内关穴,分成三组,使用不同的刺激频率,在刺激强度相同的情况下,对针麻效果进行观察,结果如下。  
        
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    • 针刺复合麻醉施行阴式全子宫切除术31例总结

      张仁惠, 梁万钧
      1982(3): 192-195.
      摘要:为探索解决针麻手术“三关”问题,我们与妇产科组成了手术小分队,深入农村为子宫脱垂患者,采用针刺复合麻醉施行阴式全子宫切除术31例,其中包括2例曼氏改良术,其成功率为87.1%,现将临床应用情况小结如下。临床资料 31例中,年龄最小38岁,最大63岁,多数介于45~50岁之间,手术时间最短1小时In this paper thirty one cases of vaginal total hysterectomy under combined acupuncture anesthesia are described  
        
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    • 伤害性刺激对躯体感觉皮层单位放电的影响及电针效应

      徐维, 董文成, 陈正秋, 谢京南, 戎象棣
      1982(3): 196-204.
      摘要:大脑皮层在针刺镇痛中的作用是研究针刺镇痛原理的课题之一,以往我们曾在正常人、颅脑手术病人以及实验动物上,用大脑皮层诱发电为指标研究机体对痛刺激(或伤害性刺激)时的大脑皮层诱发电位,并观察某些镇痛药及针刺的影响。  
        
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    • 损毁大白鼠中脑中央灰质对针刺镇痛效应的影响

      李希成, 黄辰格, 刘盛田, 张长城, 潘喜娟
      1982(3): 205-208.
      摘要:电刺激大白鼠、兔、猫、猴和人体的中脑中央灰质或向中央灰质注射微量吗啡、内源性吗啡样物质,可以抑制由各种伤害性刺激作用于周围神经、皮肤、内脏或牙髓所引起的疼痛,而且这种抗痛作用能为纳洛酮部分或完全逆转。此外,中央灰质也是鸦片受体和内源性吗啡样物质产生得比较多的一个部位。由此可见,中央灰质是脑内一个重要的痛觉调制结构。然而,An apparatus of exposed type for restraining the rat in our acupunc- ture analgesia research has been used. During the experiment the rat was restrained on a wooden base having a shallow trough with two canvas- bands which passed over the posterior of the animal's shoulders and the anterior of its coxae respectively. Tail-flick and screaming in response to electrical stimulation of the tail skin of rat were taken as indices of pain. The experiments were divided into three groups:1) the unilateral elec- trolytic lesions of the midbrain central gray, 2) bilateral electrolytic les- ions of the central gray, 3) sham operation. The effects of acupuncture analgesia in the animals with unilateral and the bilateral electrolytic les- ions of the central gray were markedly reduced, while no significant change of effect was noted in the third group. It is suggested that the midbrain central gray might play an important role in the process of acupuncture analgesia.  
        
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    • 任可, 咼中茂, 张桂林
      1982(3): 209-215.
      摘要:在针刺作用原理研究中,人们发现针刺效应与针刺后交感神经系统机能活动的变化有较密切的关系。有的工作表明,针刺可使交感神经活动受到相对抑制;也有人报道钎刺对交感神经活动有兴奋作用。己经知道,中枢肾上腺素能机能与外周交感神经活动之间存在着复杂的关系。中枢肾上The post-ganglionic discharges from the splanchnic nerves in 48 rabbits were recorded. Arterial blood pressure was also recorded in some exper- iments. After electro-acupuncture at "Tsusanli" point the splanchnic discharges were potentiated while the inhibitory phase of costo-visceral reflex was di- minished. This showed that electro-acupuncture had an excitatory action on sympathetic activity concerned with viscera. The splanchnic discharges were potentiated after intraventricular in- jection of alpha-adrenergic antagonist phentolamine (0.5mg) or beta- adrenergic agonist isoproterenol (0.06mg). Intraventricular injection of beta-adrenergic antagonist propranolol (0.12mg) or alpha-adrenergic agonist methoxamine (1mg) induced attenuation of splanchnic discharge and the excitatory action of electroacupuncture was reduced or abolished. These results showed that the effects of electro-acupuncture on sympa- thetic activity had something to do with adrenergic receptors in central nervous system, in which the beta-adrenergic receptor presented an agon- istic effect, but alpha-adrenergic receptor exerted an antagonistic effect, on acupuncture.  
        
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    • 延脑网状巨细胞核电刺激对内脏伤害性反应的影响

      黎春元, 李俊成, 侯家玉, 李丽娜, 朱丽霞
      1982(3): 216-219.
      摘要:有关延脑内侧网状巨细胞核与痛和镇痛关系方面的报道前已提及,延脑巨细胞核不仅参与伤害性感受而且与吗啡镇痛有关,它是吗啡镇痛的高敏感区。也有人指出此核团是脑干下行性调制疼痛的重要部位之一。我们过去的工作说明此核团参与针刺抑制内脏痛的整合作用。最近我们观察到针刺诱导可改变该核团神经元的兴奋性,其中部分神经元兴奋性的变化可能与巨细胞核通过上行及卞行通路参与痛觉的调制有previous work in our laboratory showed that reticular gigantocellular nucleus of medulla oblongata was involved in integration in acupuncture analgesia. In order to study further the role of RGC in modulation of pain, we observed the effects of electrical stimulation of RGC on the noxious-evoked responses of neuronal discharge in RGC, abdominal muscle discharge and behaviour in awake, unrestrained adult cats. Of 37 neurones, the noxious-evoked response of 23 was inhibited by the RGC stimulation, and the abdominal muscle discharge and behavioural response were attenuated at the same time in 16 of them. While in ano- ther 6 of 37 neurones it was observed that the noxious-evoked response in neuronal discharge was increased by RGC stimulation, in concordance with the increase of abdominal muscle discharge and behavioural respo- nses. Our experiments showed that the RGC is not only related to noci- rception but also involved in pain modulation. It is evident that the RGC is an important nucleus with complex function in regulating system of pain and anti-pain.  
        
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    • 刘惠慈, 陈起亮, 高爱莉, 殷伟平, 李金华
      1982(3): 220-223.
      摘要:前列腺素(PG)在人体各组织广泛存在,具有许多生理功能,各种哺乳类动物的脑内均含有合成PG的酶体系。大家都知道PG在外周有致痛作用。对中枢神经系统有镇静和镇痛效应。给猴、猫、大白鼠皮下注射PGE动物表现有镇静和镇痛效应。临床资料也表明针麻效果好的病人在血浆中PGE升高。在针刺镇痛过程中脑内环-磷酸腺苷(cAMP)含量变化只见个别有报道。本实验观察唇针镇痛过程中顶It is well known that the neurotransmitter systems in brain play an important role in acupuncture analgesia, and that the release and me- tabolism of neurotransmitters have an intimate relation with cerebral prostaglandins (PG) and cAMP. In the present investigation the changes in PG and cAMP concentrations in parietal cortex during lip-acupuncture analgesia were observed. The pain threshold of rat measured by K+ iontophoresis-tail flick test in experimental group was increased more than 300% after lip-acupunc- ture for 30 minutes, i.e. the lip-acupuncture had a significant analgesic effect. At this time, the PGE concentration in parietal cortex measure by radioimmunoassay was 117.0±7.1pg/mg. It was significantly higher than that in control group (87.5±7.0pg/mg) (P<0.05), while no signi- ficant changes in PGF concentration were observed. The cAMP concen- tration measured by competitive protein binding analysis was 1.65±0.13 pmo1/mg in parietal cortex after lip-acupuncture. It was also significant- ly higher than that of control group (1.02±0.08 pmol/mg) (P<0.01). Experimental results indicate that PGE and cAMP concentrations in parietal cortex were significantly increased after lip-acupunctare. Accor- ding to the previous results in our laboratory it is suggested that the re- lease and turnover of neurotransmitters, especiolly 5-HT, might play cer- tain role in the increase of PGE and cAMP levels in parietal cortex af- ter lip-acupuncture.  
        
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    • 狗胃粘膜中APUD细胞与针麻效果的关系

      于一, 周舒, 郭艳茹
      1982(3): 224-228.
      摘要:5-羟色胺(以下简称5-HT)是体内重要的生物胺类,分别由中枢神经系统的许多神经元及消化道粘膜的嗜银细胞产生,其作用极为广泛,在脑内被视为神经介质之一,在外周对胃肠活动,血管通透性及血液凝固起着重要作用,并被视为致痛物质。针刺可以抑制人胃粘膜嗜银细胞释放5-HT,改变病人血中游离5-HT的含量以及抑制血小板释放5-HT。为进一步了解针刺对致Specimens of gastric mucosa removed from 10 dogs subjected to subtotal gastrectomy (8 under acupuncture anesthesia and 2 under drug anesthesia) were observed under electronmicroscope. 6 types of APUD cells in the gas- tric mucosa were found. The immature endocrine cells showed no correla- tion with the effectiveness of acupuncture anesthesia, whereas the propor- tions of EC cells and ECL cells were correlated with the effectiveness of acupuncture anesthesia. There were more EC cells and less ECL cells in cases of grade I, but it was the opposite in cases of grade Ⅲ. The ECL cells might be considered as the liberation type of EC cells. From this, we consider that the primary effect of acupuncture anesthe- sia lies in inhibiting the 5-HT liberation of APUD cells in gastric mucosa, but the differentiation and the maturation processes of such cells might not be influenced greatly.  
        
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    • 针刺诱发感传对冠心病心绞痛病人的心脏收缩间期的影响

      孟竞璧, 刘瑞庭, 须惠仁, 赵长信, 荆尔滨
      1982(3): 229-234.
      摘要:针刺对冠心病心绞痛病人已有明确的疗效,并能改善左心功能状态,为了进一步探讨针刺感传气至病所与疗效有否关系,我们采用心电图、心音图,颈动脉搏波图和心尖搏动图(ACG)同步记录,分析心脏收缩间期,了解针刺感传的敏感度不同和无感传对冠心病人的疗效有否差异,现将观察结果报道如下:The purpose of this study was to approach the relation between the PSC induced by acupuncture and the therapeutic effect of angina pectoris of coronary heart disease. The non-invasive methods, such as ECG, PCG, ACG and carotid pulsilogram were recorded synchronously to analyse the cardiac diastolic and systolic intervals. Patients were selected according to the criteria of diagnosis at the National Conference for Coronary Heart Disease held in 1974, and 123 cases, 68 male and 55 female, aged 33 to 75 years, with typical clinical symptoms and recent different changes of the ST-T wave in electrocar- diograms were studied. The patients were divided into three groups, one group (48 cases) indicated the acupuncture sensation being at the location of a point: in another group (43 cases) acupuncture sensation was propagated along the pericardium channel over the elbow joint, and in the 3rd group (32 cases) it was propagated to the chest over the shoulder reaching the affected area. Neiguan was needled bilaterally. In the same way, three records were made before acupuncture, re- taining for 15 min and immediately after withdrawal of needles during the period of observation. Acupuncture could slow down the heart rate markedly in 123 patients suffering from angina pectoris, significantly prolong QA, MS and SF, and definitely shorten PEP and decrease PEP/LVET, indicating that acupuncture may improve the function of the left ventricle of the pa- tient. ICT was significantly shortened, LVET prolonged, and LVET/ICT increased, indicating that the force of myocardial contraction was stron- ger after acupuncture. The decrease in A wave per cent in ACG indica- tes that the left ventricular end-diastolic pressure was decreased by acupuncture. The difference of the main parameters between these groups showed no statistical significance. This experiment demonstrated that the main parameters of the car- diac systolic interval of the patients with angina pectoris were improved and some good results obtained. However, there was no statistical signi- ficance among these groups, ie, PSC induced by acupuncture was not re- lated to the therapeutic effect.  
        
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    • 心包经循经感传前后心阻抗图的变化

      盛玲玲, 杨红英, 铁双玉
      1982(3): 235-237.
      摘要:我们在过去心包经循经感传时对心率影响工作的基础上进一步探讨心包经循经感传心阻抗图的变化,在感传过程中心率变化时心输出量、心脏指数等心功能指标有何影响。方法对象:皆为7~12岁经胸透、心电、听诊检查、心肺正常之儿童,男23例、女28例共51例分二组。 1.心包经有感传组:20例 2.心包经无感传组:31例步骤:有感传儿童静卧10~20分钟后用Eifty-one normal children ranging from 7-12 years old were studied. Among them propagated sensation (PS) was observed in 20 cases and no PS in 31 cases. When the left pericardium channel PS travels to the precardiac region. electrocardiogram, dz/dt max. impedance cardiogram and phonocar- diogram were recorded and the following obsevations were made Heart rate (HR) Stroke volume(SV) Cardiac index(CI) Cardiac output(CO) Shortening of the preejecton period(PEP) Left ventricular ejection time(LVET) PEP/LVET Q-Z dz/dt max. Heather index (HI) When the pericardium channel PS reached the precardium, HR, CO, CI, were all increased with statistical significance. In the group without PS, the HR alone was changed. According to the above results, it may be con- sidered that the pericardium channel is closely related to the heart. When pericardiun channel PS exists not only HR but also the cardiac function (CO, CI) increases. For the group without PS, no statistical significance was found in any of the indices.  
        
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    • 截肢前后隐性循经感传线低阻抗性的研究(初步报导

      祝总骧, 徐万鹏, 谢君国, 黄时富, 徐瑞民
      1982(3): 238-239.
      摘要:以前工作已经证明绝大多数人沿着古典的经脉循行线,都有对机械,对电刺激产生局限性很强的感觉,称为隐性循经感传线(LPSC)。这是一种普遍的,生理的经络现象。生物物理方面,这条线具有较邻近皮肤电阻为低,电位为高,以及能发出较高亢音调的特性。这些事实支持我们在六年前提出的关于这条LPSC线On 5 cases of cancer in orthopaedic ward, the low impedance charac- teristics of the lines of latent propagated sensation along channel of limbs were determined before and after amputation. After operation, it was found that the low impedance nature of the lines of latent propaga- ted sensation along channel still exist on the excited limbs as before.  
        
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    • 1982(3): 186-187.
      摘要:Sixty cases (male 31, female 29) of posterior cranial fossa operationunder acupuncture anesthesia were summarized. These cases included:acoustic neuroma: cerebello-pontine angle tumor; invagination of cranialbase; resection of trigeminal nerve root by post route; tumor of IV ven-tricle; neura1gia of glossopharyngeal nerve and so on.  
        
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