摘要:针刺麻醉下胃部分切除术,多年来临床实践证实,确有术中安全性大,术后并发症少及恢复快等优点,也存在镇痛不全等特点,除有个体差异因素外,对针刺麻醉方法及手术操作技术尚需进一步探讨和改进,以适应其麻醉的特殊规律。自1976年7月~1982年6月间采用全层外翻连锁缝合法胃部分切除术治疗溃疡病及其良性并发症共529例,其中针刺麻醉132例,取得满意效果。本方法对组织损伤轻、刺激小,便于推广。无手术死亡率,未见与手术有关的远、近期并发症。现就手术方For the past few years, 529 cases (132 cases with acupuncture anesthe- sia) of subtotal gastrectomy with whole stratum everting chain suture plus seromuscular laver interrupted embeding had been performed achieved good results.No patient died of surgical operation. Neither early nor late compli- cation directly associated with operations were observed. Among them, 230 cases were followed up for 1-5 years. Observation of animal experiment demonstrated that using this surgical operative technique, the healing and repairing process of gastic anastomosis in rabbitss were in accordance with the general healing process of stomach wall.
摘要:在人和动物的单侧迷路被破坏后会出现眼球震颤和躯体偏斜等前庭平衡紊乱的症状,但经过一段时间后,这种前庭平衡的紊乱能得到部分的代偿,深入研究这种前庭代偿过程,将有助于阐明人类内耳迷路疾病的机制。目前已经知道,前庭代偿过程和中枢神经系统各个部分以及外周感受器的传入冲动有密切的联系,阻断躯体感觉感受器的传入冲动能减慢前庭代偿过程,电针刺激也能引起躯体感觉感受器的兴奋,但电针能否影响前庭代偿过程的工作尚未见报道,为此,我们对破坏单侧迷路后的30只豚鼠The experiments in guina pigs were carried out to observe the effect of electroacupuncture on the compensation of vestibular durine unilateral lesion of labyrinth. It was shown that the vibration of eyeball were improved and deflection of head were insignificant with electroacupuncture.
摘要:脑内多巴胺能神经元的细胞体主要分布在黑质致密部,由此发出黑质纹体束进入同侧尾核、壳核和杏仁核。尾核内多巴胺(DA)浓度增高时,可能有对抗电针镇痛的作用。本文向黑质内微量注射DA,观察当黑质DA能神经元本身的胞体和树突受到高浓度DA的作用时,对电针镇痛作用的影响。方法实验动物为白色家兔,体重2公斤左右,雌雄不拘。实验前,在氨基甲酸乙酯(0.75克/公斤)轻麻下,按Sawyer氏图谱,向两侧黑质埋植不锈钢管(P_5、H_(-5)、L、R_4)。套The dopaminergic neurons in the brain are mainly distributed in the pars compacta of the substantia nigra and send up the nigrostriatal bundle to ipsilateral caudate, putamen and amygdalae nucleus. The increase of concentration of dopamine in the caudate appears to have an electroacupun- cture analgesic effect. In the present study we injected dopamine (7.5μg/μl) 2 μl into the bilateral substantia nigra through the chronic implanted stainless steel cannulae in order to observe the effect of dopamine in the substantia nigra on the electroacupuncture analgesia. The pain threshold was determined by the latency of withdrawal of head when the radiant heat was applied on the nose tip of rabbits. The results showed that injection of dopamine into bilateral substantia nigra increased the pain threshold and the analgesic effect by electroacu- puncture in "Zu San Ii" Was also increased. The dopamine in the substan- tia nigra might play a negative feedback inhibition effect on the cell bodies and dentrities of the dopaminergic neurons, and therefore the dopamin discharge from their axon terminals was reduced.
摘要:神经系统的中枢部分和外周部分是统一整体中不可分割的两个部分。虽然由于血脑屏障的存在,限制了某些化学物质的直接交流,以至中枢神经递质存在着相对独立性,对于保证中枢物质环境的相对稳定具有一定意义,但它们中间还是存在着某种有机的联系。对大多数物质来说,这种屏障都是相对的、部分的,而不是绝对的。即使在脑的不同区域,这种“屏障”的程度也各不相同。大量的实验资料表明,神经递质的代谢过程和生理作用与整个机体的生理功能和行为之间有着密切关系。例如不同的神经递质系统均在一定程度上参与痛与镇痛。中枢和外周的同名递质,是否在统一By fluorescence spectrophotometry we observed the changes of 5-hydr- oxytamine (5-HT), 5-hydroxyindolacetic acid (5-HIAA), norepinephrine (NE), tryptophan (Trp) and tyrosine (Tyr) in cerebrospinal fluid (CSF) and blood in nine patients After acupuncture the amount of 5-HT system in CSF and in blood of nine cases had contradiction between central nerve and peripheral nerve. The 5-HT/NE in central nerve was higher than that in blood.
摘要:针刺“人中”穴具有升高血压的作用已被大量临床和实验工作证明。近年来对于中枢介质参与血压调节也逐渐引起更多的注意。为了探讨针刺升高血压的中枢机制,乃采用不同药物作侧脑室内注射,观察对电针升压作用的影响。方法采用220~280克大鼠,性别不拘,以每公斤1.2克的乌拉坦皮下注射,在麻醉下做颈动脉插管和双侧颅骨钻孔(距前囱2毫米,距中缝线2毫米)备测量血压和侧脑室注射用。使用SJ—41型多导生理记录仪描记血压和心率。首先描记基础血压和心率,It is well known that the blood pressure may be increased by electro-acu- puncture on certain point, but the relationship between central neurotran- smitter and the pressor effect of acupuncture has been rarely studied. In this article the roles played by the central cholinergic activity in the pressor response of electroacupuncture(EA) are reported. The pressor effect of EA on "Renzhong" point was demonstrated in anesthetized rats. This pressor effect was reenforced by ICV injection of 2.5~5μg neostigmine but depressed by previous ICV administration of HC-3 and atropine. Either naloxone or pentolamine injection exerts some inhibi- tory effect on the pressor response of EA. Therefore the pressor effect of EA is intimately related with central cholinergic activity, Both opiate re- ceptor and α-adrenergic receptor are also invovved in the pressor response of EA. The reenforcing effect of neostigmine on pressor response of EA can be antagonized by naloxone but not by pentolamine. This result suggests that some functional linkage exists between the central vasomotor control of cholinergic system and the opiate like substance of the brain
摘要:许多临床资料表明按摩、针灸等中医治疗方法与运动系统有关,按摩疗法的手法之一——推荡法又名推动法适于治疗外伤肿痛等病。针刺治疗痛症过程中,运动患部或广泛的伸展运动可提高疗效针形电极插入肌肉时或在运动终板区微小的移动后,可见有关的电发放;实验研究证实针刺得气与肌电话活动有关;穴位里以肌梭感受器为主;中医认为穴位多在“分肉间”、“两筋间”。这些资料表明,推动法按摩(被动性运动)可治疗肿瘤;运动可提高针刺治疗癌症的疗效;而针刺本身Thc prescent experiments were performed on 50 healthy subjects(22 males, 28 females, ranging in age from 20 to 57 years). The threshold of pain was measured on the back of the hand by spring painmeter. The subject exercised his ipsilateral wrist 2 to 4 times per second. The exercise resulted in definite inhibitory effects on the threshold of pain. The effect was sta- tistically significant(P<0.01). These results seem to indicate that moving thoracic limb can inhibit the sense of pain. The moving factor is a partial scientific foundation of the massage therapy and the acupuncture treatment for pain.
摘要:针刺治疗癌症过程中,运动患部或作广泛的伸展运动可提高镇痛疗效;针刺镇痛使用电针时可见明显的肢体抽动或局部肌颤,这些临床资料都表明针刺镇痛与运动系统有关。一些实验资料表明:针感来自深部组织,主要为肌肉;针感感受器以肌梭为主;针刺得气与肌电活动有关;针形电极插入肌肉时或在运动终板区微小的移动时;,可见到有关的电发放。以上资料提示,针刺时运动系统被兴奋,它可能是参与中枢镇痛的组成部分。我们已在In some previous studies we verified that the factor of moving plays a role in acupuncture analgesia. This study further examines the effect of wrist exercises on event-related potential and subjective pain report. Methods: The present expriments were performed on 20 normal adult subjects and patients with intact sensation. Painful stimuli were applied to a middle nerve of one side forelimb and the cerebral evoked potentials we- re recorded contralaterly and subjective pain reports were recorded. The subject exercised his contralateral wrist 2 to 4 times per second. The execise can produce significant analgesic rating. The effects was statistically significant (P<0.01). The amplitudes of the cerebral evoked potentials with latency 160-260ms component with close relation to pain si- gnificantly decreased. It was statistically significant (P<0.05). These results seem to indicate that moving wrist can inhibit the painful sense and factor of moving plays a role in analgesia. It is a partial physi- ological foundation of acupuncture analgesia.