最新刊期
1986年第4期
- 摘要：祖国医学很早就提出针刺“人中”有急救垂危病人复苏的作用。一些临床和实验研究证明针刺“人中”有抗休克的作用,并提出针刺抗休克可能与某些神经内分泌体液因素有关。用组组化学方法从形态学上证明,针刺“人中”可使失血性休克家兔心肌内减少脱失的儿茶酚胺萤光得到恢复使之接近正常。心钠素(Cardionatrin)是近年从人和大白鼠心房组织中分离提取的一类生物活性多肽,有人认为是新的内分泌39 adult healthy male rats were divided evenly into three groups. The rats attacked with hemorrhagic shock by bleeding via left femoral artery. Bleeding was continued till mean blood pressure of 40 mmHg was obtained. The state of hypotension was maintained for 1(1/2) hours in hemorrhagic shock group. 1/2 hour after bleeding electroacupuncture at "Renzhong" point was given for 1 hour in electroacupuncture group. The rat's hearts were excised after experiment. Peroxidase antiperoxidase immunocytochemistry method of Stenberger was used to demonstrate the atriopeptin like immu- noreactive granules in rat's atrium. The atriopeptin like immunoreactive granules in hemorrhagic shock rat's atrium were increased than that of normal and electroacupuncture group. The immunoreactivities of granules in atrial cardiocytes were marked increased by hemorrhagic shock. The density and distribution of atriope- ptin immunoreactive like granules in rat's atrium of the control showed a similar pattern to that of hemorrhagic shock animals given electroacupu- neture. It was indicated in our result that the electroacupuncture might have an anti-hemorrhagic shock effect and atriopeptin as one of the neuroend- ocrine might play a certain role in electroacupuncture anti-shock.991|0|0更新时间：2023-08-11
- 摘要：本工作旨在观察针刺人中对失血性休克动物的失血量、死亡率、死亡时间、输液量以及一系列血流动力学指标的影响,以期阐明针刺“人中”是否具有抗休克作用,并着重观察其抗休克作用的血流动力学特点,为进一步探讨针刺的调整作用提供依据。方法实验于58只猫和39只狗上进行,雌雄不拘,随机地将动物分成针刺组与对照组。猫在乙醚麻醉下、狗在硫贲妥钠静脉麻醉下手术,术后静脉三碘季胺酚麻痹骨骼肌并人工呼吸,以便在动物清醒的情况下进行观The work was carried out to observe the effect of Renzhong (philtr- um) needling on volume of blood loss, motality, dead time, amount of blood transfusion and a series of indices of hemodynamics during hemor- rhagic shock, in order to show whether acupuncture had anti-shock effect or not and what its characteristics of hemodynamics were. The experiments were performed on 58 cats and 39 dogs with conscious- nese. Renzhong needling could increase the volume of blood loss to cau- se standard hemorrhagic shock, decrease the mortality and delay the dead time and decrease the amount of blood transfusion to bring blood pressure to normal level in the animals with shock. It could also improve the re- nal and intestinal blood flow, increase the cardiac index and stroke volume and decrease the total peripheral resistance during hemorrhagic shock, so as to correct the disturbance of low cardiac output and high peripheral resistance to a certain extent. The above-mentioned results suggest that Renzhong (philtrum) needling has an anti-shock effect and the effect may relate to improvement in both circulation of the visceral organs and in cardiac function.767|0|0更新时间：2023-08-11
- 摘要：我们曾在休克动物上证明针刺人中具有抗休克效应,并认为这种效应与改善内脏器官血流量及心脏功能有关。国内先后报道刺激“人中”等灾可引起明显的加压反应,但对针刺加压反应的生理特性与本质尚缺乏系统研究。本工作对针刺加压反应进行系统的观察与研究,以期阐明其生理特性与本质。方法实验在104只猫与16只家兔上进行,雌雄不拘。猫在乙醚麻醉下手术,手术后立即停止麻醉,家兔则在局麻下进行手术。随后从静脉注射三碘季胺酚(4～6毫克/公The work was carried out to observe functional changes of the resis- tance blood vessels, the capacity blood vessels, the heart and the other autonomic effectors during the pressor reaction induced by acupuncture, in order to show its physiological characteristics. The experiments were performed on 104 cats and 16 rabbits with con- sciousness. The pressor reaction induced by acupuncture accompanied con- traction of the resistance blood vessels, increase of total peripheral re- sistance, contraction of the capacity blood vessels and reabsorption of ti- ssure so as to induce increase of blood pressure. At the same time, it accompanied augmentation of both cardiac contractility and cardiac work so as to keep cardiac output at normal level during increase of total peri- pheral resistance. The above-mentioned cardiovascular reactions were induced through sympathetic nerves. Moreover, it accompanied contraction of the nictitating membrane, dilation of the pupil, contraction of the bladder and contraction or dilation of the small intestine. Those effects were indu- ced through sympathetic nerves or parasympathetic nerves. The above-mentioned results suggest that the pressor reaction inducad by acupuncture accompanys widespread excitation of autonomic nervous system. Its physiological characteritics are similar to those of the pressor reaction induced by stimulation of the saphenous nerve. Both of them be- long to nonspecific cardiovascular reflex reactions. However, the pressor reactions induced by decreasing the pressure of carotid sinus and stimula- ting carotid chemoreceptors respectively do not accompany widespread excitation of autonomic nervous system, just accompany functional changes of the heart and certain local blood vessels. Both of them belong to spe- cific cardiovascular ref1ex reactions, which play an important role in re- gulation of cardiovascular functions.661|0|0更新时间：2023-08-11
- 摘要：失血性休克后,肝糖原大量分解形成高血糖,而交感神经及其有关神经递质——儿茶酚胺(CA)是对肝释放葡萄糖的重要因素。因此了解在失血性休克时肝的交感神经递质的变化是一个重要方面。由于对实验室常用动物肝实质内是否存在交感肾上腺素能神经还有争论,我们在针刺“人中”对失血性休克家兔肝组化的研究中,以诱发CA荧光的方法观察了家兔肝实质的肾上腺素能神经分布及其在失血性休克时的针刺效应。826|0|0更新时间：2023-08-11
- 摘要：大失血后高血糖是由于肝细胞糖原分解释放葡萄糖。我们已观察到针刺“人中”可对失血性休克家兔肝糖原有显著的影响,因为磷酸化酶是糖原分解的限速酶,以组化方法显示出磷酸化酶的活性,可进一步了解针刺“人中”对失血性休克家兔肝细胞功能的影响。材料和方法雄性家兔104只,右股动脉放血,失血量为20毫升/公斤,血压下降到50毫米汞柱以下,失血后10分钟(7例)、30分钟(13例)心电监视和血压同时都出现濒危者(19例),平均为67分钟取材。针刺104 male rabbits were used in this experiment. The groups divided and the order of physiological experiment was just the same as that in "The effect of acupuncture at "Renzhong" on hepatic glycogen of rabbits during hemorrhagic shock". Phosphorylase is a rate-limiting enzyme for glycogenolysis. The straight chain unbranched polysacchride associated with phosphorylase, stains bluc- black with iodine, distributed mainly at periportal liver cells under nor- mal condition, while the branched polysaccharide stains red brown distri- buted at perivenous zone of hepatic lobule. The phosphorylase was was activted largely in hepatic lobule and de- monstrated the glycogenolysis is taking place 10 min. after bleeding. The phosphorylase of hepatic cells disappeared and depleted gradually 30 min. After bleeding. The phosphorylase was decreased more quickly among these three hemorrhagic groups and there was a statistic significance. The phosphorylase of hepatic cells in acupunctured group was activted continually 30 min. after bleeding, it was distributed at the hepatic cell membrane bordering on sinusoids and then decreased. but a greater extent than that without acupuncture. There was a statistic singificance between the acupuncture groups and non-acupuncture groups. It is benificial to sup- ply various tissues and orgens depleted out of hemorrhage with energy from glycogenolysis.767|0|0更新时间：2023-08-11
- 摘要：很早就知道失血后血中葡萄糖显著增加是因失血后肝细胞经过糖原分解释放葡萄糖的缘故。以组化方法观察失血性休克发生后肝糖原的变化以及针刺“人中”对失血性休克动物肝糖原的影响是探讨针刺作用原理的一个环节。材料和方法雄性家兔103只,体重2.1～3公斤,分为9个组:失血性休克3个组,从右股动脉放血,血压降至50毫米汞柱以下,平均失血为20毫升/公斤,人工呼吸,并有心电监护,于失血后10、30分钟以及动物濒危时(平均67分钟)取材。针刺组也分为3个103 male rabbits were divided into nine groups. The blood pressure was fall down to below 50mm Hg after bleeding 20ml/kg, the hepatic blocks were excised in 10 and 30 min. and the animals were in imminent dangerous state (mean 67 min.). The animals of acupuncture at "Ren zhong" were divided into three groups: 30 min., mean 67 min. and 120 min. after bleeding. Normal, sham operation and CCl_4 injection were used as control. The histochemical changes of hepatic glycogen has been observed and measured quantitatively with Leitz MPV_2 compact microscope photome- ter. The liver glycogen from periportal to perivenous zone of hepatic lo- bule was decreased, disappeared and depleted gradually after hemorrhage. The hepatic glycogen was decreased more quickly among these three hemor- rhagic groups and there was a statistic significance. The hepatic glycogen in three acupunctured groups were also decreased ane disappeared, but much more better in time and quantity than that without acupuncture. The relation between these phenomena and their acupuncture effect was dis- cussed in this paper.887|0|0更新时间：2023-08-11
- 摘要：实验用JCR纯种小鼠,以5％的牛血清致小鼠过敏性休克,观察其针刺效应。 1.电针“人中、承浆”两穴,对于小鼠实验性过敏性休克具有良好的拮抗作用。 2.使用肾上腺素能受体拮抗剂分别阻断α、β受体,能够阻断电针的抗休克作用,说明针刺是通过某种途径兴奋肾上腺素受体而发挥作用的。 3.应用纳洛酮阻断内源性MLS受体或以其它方法抑制β-内啡肽的释放,则电针抗过敏性休克的作用增强。提示药物能弥补针效的不足,发挥针药协同作用是一个值得研究的途径。978|0|0更新时间：2023-08-11
- 摘要：针灸治疗消化系统疾病有很好的疗效,主要是针刺对消化道功能有良好的调整作用。我们在针刺对消化性溃疡研究中发现,针刺能调整胃的功能。针刺狗“足三里”、“脾俞”等穴可使胃的碳酸氢盐和钠的分泌明显增加,而胃酸分泌明显减少。说明针刺是治疗溃疡病有效方法之一。实验进一步证明,针刺使胃酸下降有胆硷能神经参与作用。同样针刺对胃运动功能作用也是明显的。实验证明,针刺狗“人中”穴可使胃的运动减弱并伴随5-羟色胺和胃泌素含量降低,若毁损延脑去甲肾上腺素核团则此作用减弱,提示该脑区与针刺“人中”引起胃运动抑制有关。临床上常见的胃窦运动过速病人,采用针刺治疗可能有助于症状的改善。此外,针刺还可以改变脑内胃泌素肽的释放,提示针刺对中枢神经系统脑肠肽的合成与释放有积极的调整作用。758|0|0更新时间：2023-08-11
- 摘要：针刺足三里穴对胃肠道运动功能的影响较大,表现为兴奋性效应,和兴奋或抑制性效应,即调整作用。但是否存在穴位特异性,尚值得进一步探讨。本文以胃电图和肠鸣音为针刺效应指标,采用针刺提插补泻手法,观察不同经穴的针刺效应。方法一、体表胃电图记录方法使用RM-46型四导生理记录仪描记,时间常数为2秒,高频滤波为100赫,并联22微法电容,纸速60毫米/分。采用单极引导法。体表电极用一对氯化银电极,记录电极置于受试者腹壁左乳头与脐连线中点,此The motive function of the stomach and intestine can be effected by acupuncture of point Zusanli, showing excitation or inhibition. But the problem about the specificity of acupoint effects needs to be studied and discussed. In this paper, using electrogastrogram(EGG) and the intesti nal gurgling sound as index, the acupuncture effects of different points were observed with manipulations of reinforcing and reducing. 1. EGG was recorded in 38 parients with asthenia of the spleen and stomach, in 20 cases of the reinforcing group, the amplitudes of EGG were increased dominantly and in 18 cases of the reducing group, their amplitudes were lowered. It was shown that both the reinforcing and redu- cing manipulations was able to induce different acupuncture effects 2. The intestinal gurgling sound of 256 petients with asthenia of the spleen and stomach was observed. In the reinforcing group, 86 of 105 ca- ses were decreased (81. 9%), but 19 cases were increased (18. 1%), showing the decrease is main. In the reducing group, 67 of 151 cases were increased (44. 4%), but 84 cases were decreased (55. 6%). The number of cases with increase of the intestinal gurgling sound in the reducing group were much more than the reinforcing group with statistical significance (P <0. 01). 3. EGG of 79 patients with asthenia of the spleen and stomach were observed. The average difference in the amplitude of EGG between pre- and post-acuptincture in the Zusanli group was 58. 4mV, with statistical sig- nificance. In the Yanglingquan group, the non-point group, and the con- trol group, it was 8.2, 6.5 and -5.7 respectively, with no statistical sig- nificance. The results indicated that acupuncture of Zusanli produced a remarked effect on the amplitude of EGG. 4. The intestinal gurgling sound of 54 patients with asthenia of the spleen and stomach was observed. The intestinal gurgling sound in Zusanli group were decreased mainly, the mean of frequency were decreased 34. 29%, with significant statistical differenct. While in rhe Yanglingquan group and the control group had no obvious change of the intestinal gurgling sound. It was suggested that acupuncture of Zusanli induced a remarked effect on the intestinal gurgling sound. Manipulations of the reinforcing and reducing may induce different acupuncture effect. The method of reinforcing induced the response of vasodi- lation, but the reducing method induced the response of vasoconstruction. The reinforcing method produced a increase of the intestinal movement, but the reducing method reduced its movement. In the experiment it was found that the reinforcing method increased the amplitude of EGG and de- creased the intestinal gurgling sound: but the reducing method decreased the amplitude and increased the intestinal gurgling. These results provide the selection of acupuncture manipulation for study of acupuncture regula- ting the function of the solid and hollow organ. In this study the patients were diagnosed as pepticulcer, chronic gas- tritis and chronic non-specific colitis with the gastroscopy and the sigmoi- doscopy, and the reingorcing method was used. Some one considered that the effect of Zusanli is non-specific for the intestinal movement, but most results indicated that there was a certain specificity in the effect of acupuncture of Zusanli on the movement of the stomach and the intestine. Recent years, in the study of EGG, it has been reported that Carba- chol which potentiates stomach peristalion may increase the amplitude of slow wave of the superficial EGG; But Atropin which inhibites the stomach peristaltion may decrease the amplitude of slow wave of the superficial EGG. It is suggested that the slow wave of the surperficial EGG can re- flect the function of the stomach movement to some extent. In this expe- riment it was observed that acupuncture of Zusanli produced a significant increase (P<0.05) in the slow wave of EGG. But acupuncture of Yangling- quan and non-point did not induce any change of the slow wave. Acupun- cture of Zusanli also induced a significant influence on the intestinal gurg- ling sound. But effect on it was not produced when Yanglingquan and control was stimulated. These results indicated that acupuncture of Zusanli is able to regulate the function of stomach and intestine movement, and it has a certain specificity.919|0|0更新时间：2023-08-11
- 摘要：针刺对机体胃肠道功能的调整作用已被实验研究和临床实践证实。但以往的报道,偏重于针刺即时的效应,关于针刺后效应对胃肠运动的影响了解甚少。本文运用体表胃电图、肠电图对针麻手术后胃肠运动功能进行观察,发现针刺麻醉后,这种长时间运针所产生的针刺后效应,能减轻因手术刺激,麻醉药物引起的胃肠功能紊乱,促进术后胃肠功能的恢复。现将结果分述于下: 方法 1.观察对象:66例胃大部切除术中针麻20例、硬膜外麻醉26例、硬膜外麻醉In this article, the observation on the motility function of gastro ntes- tinal tract after operation under acupuncture anesthesia (AA) was under- taken. It was discovered that after application of acupuncture for a long time, the post-acupuncture effect could alleviate the disturbance of gastro- intestinal function induced by operation and medication aud promote the post-operative gastrointestinal recovery. The results are seperately stated as follow: 1. The infuluence of acupuncture on the duration for initial release of gas from anus after operation. Usually the recovery of motility function of intestine is valualed by the duration for the initial release of gas from anus after operation. In the acupuncture group (Gr. Ⅰ), the average duration is 12 hrs., that of epidural anesthesia group (Gr. Ⅲ) 53.7hrs. The difference between the two groups is very significant (P<0.01). In the combined epidural and acupuncture anesthsia group (Gr. Ⅱ), the average duration is 47.1 hrs, 6.6hrs. earlier than Gr. Ⅲ with significant difference (P<0. 05). For investigating whether styles of operation influence the duration for the initial releasing of gas after operation, those cases With gastro- duodenostomy (Billroth Ⅰ), in which traction during operation was consi- dered to be less, were listed in Table Ⅱ. After comparison, it was clear that the average postoperative duration in Group Ⅰ was still shorter than that of Group Ⅲ (P<0. 01). The du- ration in Group Ⅱ was stiII in between the other two groups. This result suggests that acupuncture produces a predominant influence on the duration for postoperative initial release of gas, and the duration is unrelated to the style of operation. 2. The Influence of Acupuncture on Postoperative peristaltic Sound: The auscultation and sound recording of intestinal perlstalsis for 4 hrs. After operation were analyzed for the 8 groups. If 0-5 times/10 min. of peristaltic sound was taken as remarked depression, then the percentage of dapression in Gr. Ⅲ was the highest. It occupied 78% of this group. Those for Gr. Ⅱ and Gr. Ⅰ were 28. 1% respectively. The differences among the three groups were very significant (P<0. 01). The sound of intestinal peristalsis began to recover to different degrees one day after operation in the three Groups. The recovery in Gr. Ⅰ was the most prominant. While G. Ⅲ was the slowest one in the three groups. If the change of peristaltic sound in combination with the duration for post-operative initial release of gas was analyzed, It was found that the peristaltic sound were significantly depressed in the majority of the cases whose durations for post-operative initial release of gas were over 55-60 hrs. The depression of peristaltic sound was milder for those whose post- operation initial release of gas were shorter than 48 hrs. If the relation- ship between the change in peristaltic sound at the day of operation and the duration for post-operative initial release of gas in the three groups was analyzed, it was found to be negatively interrelated, i.e. if the peris- taltic sound was much depressed at the day of operation, then the du- ration for post-operative initial release of gas was longer. If depression of peristaltic sound was little at the day of operation, then the duration for post-operative initial release of gas is shorter. These results indicate that the sound of intestinal motility is intimately related to the duration for post-operative initial release of gas. Acupuncture can decrease the de- gree of depression of peristaltic sound after operation. That may be the main cause why the post-operative recovery of intestinal peristalsis is qui- cker and the duration for post-operative initial release of gas is shorter in EA+AA and AA groups. 3. The Influence of Acupuncture on Postoperative EIG: From the analysis of slow waves of EIG on body surfaces of the ca- ses in the three groups, it can be seen that the change in EIG is also in accord with that of intestinal peristaltic sound. The degree of depression in EIG is milder in Gr. Ⅰ and Gr. Ⅱ, and the duration for depression is shorter. The degree of depression in EIG is stronger in Gr. Ⅲ, and the duration of depression is longer. From picture 1 and 2, it is clear that the depression of EIG for those under AA is mider, and activity of their EIG is recovered partially after operation. The amplitude of EIG increases evidently 5 hrs. after operation. The EIG is evidently depressed in those under EA. EIG did not recovery to normal 5 hrs. after operation. It is also found that the amplitude of EIG waves increses evidently after the inducing period of acupuncture, so the influence of adjuvant drug atropine is less. While the influence of atropine in EA is quite remauked. In continuous observation of postoperative EIG, it is discovered that in those who have earlier recovery of EIG, durations for postoperative initial release of gas are also shorter. Otherwise the durations are longer. The above mentioned results indicate that the influence of acupuncture on EIG probably is the main factor that promotes the changes in intes- tinal sound or motility and duration for postoperative initial release of gas. 4. The Influence of Acupuncture on Postoperative EGG: In conti- nuous monitoring of postoperative EGG on boby surface of patients with pneumonectomy, it is found that the frequency of EGG after operation under AA has no obvious change(P<0.05). While that under drug anesthe- sia has an evident decrease. There is no recovery even 4 hrs. after ope- ration. In comparison with preoperative EGG, the differeence is very sig- nificant (P<0. 01). The result indicates that drug anesthesia possesses an inhibitory effect on postoperative EGG. While in AA, there is no such inhibition (Table Ⅲ).901|0|0更新时间：2023-08-11
- 摘要：近年来,已有大量工作探讨中医中药在临床治疗中“扶正固本”的本质与免疫系统的关系。针灸对机体免疫功能的调整作用也有过一些研究,在细胞免疫方面以往多从对非特异性的细胞防护作用的影响进行观察,如白细胞,巨噬细胞的吞噬机能在针刺前后的变化,近年来,针灸对具有免疫活性的T,B淋巴细胞免疫功能的影响已有一些报道。一些研究表明,针灸疗法能促进或调整患病机体的免疫功能,增强机体抗病能力,说明针灸疗法在治疗医学中起到了积极的作The aim of this study was to observe effects of EA on cellular im- mune function in normal man further analyse the significance of acupunc- ture therapy in preventive medicine. The observations were carried out in health subjects divided into three groups: the first EA group, 18 cases, both "Zusanli" and "Yanglingquan" acupoints stimulated by EA; The second EA group, 8 cases, "Zusanli" and "Fenglong" acupoints were stimulated by EA; control group, 9 cases were not stimulated by EA. The two EA groups received EA for 15 min- utes, once every other day, totalled 3 times. It was taken as the limit of strength of EA that the subjects felt local sense of numbness and fullness or conductible needling sensation. The percentages of T lymphocytes from peripheral blood of the sub- jects which ANAE reaction was belong to spot granular pattern and the change of activity of esterase within this kind of T cell were examined. The results were as follows: T lymphocytes with spot granular pattern were significantly increased after EA; the first EA group, p<0. 001; the second EA group, p<0. 01; but control group, p>0. 4. There were significant differences between EA groups and control group, p<0. 01; but there was no significant differen- ce between the two EA groups, p>0. 05. The esterase activity of T lymphocytes significantly increased in the two EA groups, p<0. 05, But had no significant change in control group. It was indicated that the T lymphocyte which ANAE reaction was spot granular pattern belonged to helped immune cell to bring immune function into play. So these results suggested that the function of physical immune active cell was increased by EA and could play an active role in increasing physical resistance.869|0|0更新时间：2023-08-11
- 摘要：一般认为机体对疾病的抵抗力与机体的免疫功能状态有一定的关系,患病机体常常表现出免疫功能的异常。补体是正常人血清中非特异性体液免疫因素,一方面参与机体的防御机能,可促使特异性机体发挥作用,另一方面在免疫损伤中也发挥重要作用,血清补体水平的变化也可反映机体防御机能的状态或者某些免疫病理过程的存在。我们曾观察到电针穴位有增强正常人细胞免疫功能的作用。本工作试图通过电针对正常人血清某些补体成份影响的观察,进一步分析The aim of this study was to observe the effects of EA on some co- mponents of complement system in normal man, and further analyse the significance of acupuncture in preventive medicine. Normal volunteers were divided into two groups. (1)EA group: two ac- upoints "Zusanli" and "Yanglingquan" or "Fenglong" were stimulated by EA. (2)Control group: no stimulation of EA. The EA group was given EA for 15 miuutes, once every other day, totalled 3 times. It was taken as the limit of strength of EA that the subject got the local numbness and fullness sensation or conpuctible needling sensation. The two groups of the subjects were tested for serum comblement 3(C3), complement 4(C4) and properdin B factor (PFB) contents. Then the effects of EA and the relation of age with the effect of EA were analysed. The resnlts were as follows: The content C3 was no significant change after EA (n=20), p>0.3. But in two cases of them C3 content was remarked lower than normal level which was recovered to the normal lerel after EA. The content of C4 significantly increased after EA (n=20), p=0. 05. The content of PFB also significantly increased in EA group (n=25), p<0. 05, But had no signi- ficant change in control group. The effects of EA in youth group(8 or 7 cases, age 20-27) were more obvious than in elder group (8 or 7 cases, age 41-53). The increased per- centages of C3, C4, PFB after EA were as follows: In youth group: C3, 2. 98 %; C4, 15. 40%; PFB, 30. 85%. In elder group: C3, 1.49 %; C4, 5.339 %; PFB 10.31 %. The results indicated that some components of complement system in normal man could be significantly increased by EA. It was suggested that these unspecialized immune substances were increased by acupuncture to improve the immune function and increase the effect of physical preven- ting diseases. And it seemed that the acupuncture effects in youth were more remarked than in eider,791|0|0更新时间：2023-08-11
- 摘要：肥大细胞为神经激素细胞,其颗粒中含有多种生物活性物质,在针刺中将起着重要的作用。本实验采用形态学方法,观察“足三里”穴区肥大细胞的分布和当针刺时肥大细胞的变化,为揭示肥大细胞在针刺过程中起何种作用提供形态为基础。方法本实验采用正常健康雄性大白鼠17只。平均体重为380克。观察两侧“足三里”穴共计34个穴区。实验分为两组:(1)对照组:采用正常大鼠,在1％戊巴比妥钠轻度麻醉下,为了保持穴区皮肤组织不受移动和牵拉,经断头后,取下两侧后肢,固定24小In revealing the function of mast cell for providing morphological bases under acupuucture, seventeen normal male rate were used. Totally 34 areas of both "Zusanli" points were observed, acupunctured with manupu- lation. Normal rats under slight ansthesia with 1% sodium barbiturate for keeping the point area of the skin not to be moved and pilled. Both legs cut out were after decapitation and fixed in Schaffer's solution for 24hr, then both sides of "Zusanli" areas were excised, and fixed once again and whole skin spreading specimens and wax section preparations were made. The slight ansthesia was applied to the acupunctured group as well as the control. The both side of "Zusanli" were punctured with needles keeping in the depth of the muscle layer, twirling slightly for 5 minutes, then the preparations were made that as of the control, then stained with toluidine blue. The results were observed as follows: 1. Normal distribution of mast cells in point "Zusanli", area: There were round, oval, long and irregular formed mast cells aggregated or single distributed in skin and subcutaneous tissues of the whole skin spreading specimens. Some of them were arranged along the small blood vessels in lines, especially along the subcutaneous longitudinal and transversal bra- nches and multiple branches from the superficical to deep. There were dispersed and aggregated immature and matured mast cells around the hair follicles and outer membranes of small vessels and fat cells and in the connective tissues. After continual sectional observation, The mast cells in muscle tissue were accompanid with the small blood vessels and their bran- ches passed through perimysium into connective tissues of muscle bundle and distributed dispersively or around the small blood vessels. It demon- strated that the mast cells in muscle were accmpanied with vessels. 2. Acupuncture group. The single particle was released in the sub- cutaneous tissues around small vessels, muscle bundle and connective tis- sues within muscular fibres, in sections of the preparations, above resulte indicated that acupuncture could elicit the release and lysis of particles in the mast cells around the point. Mast cell is a kind of neurohormoral cell, containing 5-HT, histami- ne, hydrolase and other biological active substances. Acupuncture could clicit the release of these particles and in which histamimine could enha- nce the vaso-permeabilities, the plasma protain could oozed out from the vasa, which activates the phagocytosis of phagocytes to phagositize the damaged tissues by acupuncture. Owing to the acupuncture elicites the damage of acupoints points. We consider that the phagocytosis of the phagocytes might purify the necro- tic tissues of acupoints points. So that the physiologic equilibrium of acupoints oints is remained.956|1|0更新时间：2023-08-11
- 摘要：用针灸治疗缺乳在针灸经典著作中早有记载,针灸疗法简便易行,疗效明显,在我国流传甚广。然而关于其作用机理几乎未有研究。本文以灵敏的放射免疫测定法证明,电针授乳期大鼠“膻中”穴可使催乳素分泌亢进,针刺“足三里”穴则效果较弱,用特异的神经毒损毁中枢5-羟色胺或去甲肾上腺素能神经终末后,针刺的上述效应即被取消。本文对所获结果的意义进行了讨论。713|0|0更新时间：2023-08-11
- 摘要：临床实践表明,针灸对多种慢性、耗损性疾病有不同程度疗效,为探索其机理,本实验做了如下动物实验观察。 1.大鼠每日腹腔注射氢化可的松3毫克/公斤,连续9天,造成动物机体耗损,动物呈现一系列肾上腺皮质机能减退状态:毛松,少动,弓背,肾上腺萎缩(重量明显减轻),血浆糖皮质激素含量明显降低等。对这种耗损动物给以电针治疗(双“肾俞”穴,电针频率15次/秒,强度以动物耐受为度,间日电针一次,每次15分钟)经9次电针后,大鼠肾上腺湿重,血浆糖皮质激素含量都显著高于模型对照组。这一结果提示,针刺可以促进萎缩肾上腺修复,改善其分泌活动。 2.由上述实验结果表明,在动物血浆糖皮质激素处于低水平时,针刺对肾上腺皮质分泌活动具有激活作用,而当动物体内保持较高和平的列源性糖皮质激素时,针刺的作用又如何呢;对中枢五羟色胺系统是否参与垂体-肾上腺系统的调节的有关报道不鲜,那么中枢五羟色胺系统是否参与针刺的调正作用,本实验就如上问题做了初步探索。大鼠一次腹腔注射大剂量长较外源性糖皮质激素地塞米松(6.8毫克/公斤体重)4小时后,动物血浆皮质酮含量显著降低,表明肾上腺皮质分泌活动处于反馈性抑制状态。对这种地塞米松动物电针15分钟(方法同实验1)后,动物血浆皮质酮水平显著升高,它表明针刺可以显著对抗外源性激素对肾上腺皮质系统的反馈性抑制。在本实验中还观察到,注射地塞米松后,大鼠间脑5-HT,5-HIAA含量明显降低,地塞米松对5-HT的合成、代谢具有抑制作用。地塞米松动物电针15分钟后,其间脑5-HT,5-HTIAA水平明显高于地塞米松对照组,但仍显著低于盐水加电针组,针刺对地塞米松动物中枢5-HT系统功能活动具有激活作用,但激活程度与血糖皮质激素水平有关,中枢5-HT系统可能参与针刺对垂体-肾上腺皮质系统的调整作用。779|0|0更新时间：2023-08-11
- 摘要：大量的人群普查和实验研究表明,高脂血症是导致动脉粥样硬化性心脑血管病的危险因素之一。世界卫生组织亦认为它是冠心病的易患因素,已将高胆固醇血症列为冠心病的诊断条件之一。动脉粥样硬化性心脑血管病是中、老年人的常见病、多发病,近年来其患病率及死亡率均有逐年增加的趋势。故设法降低高血脂对防治动脉粥样硬化性心脑血管病具有重要意义。目前,国内外均将其作为防治与研究的重点。鉴于对现有降血脂药物的疗效尚有争论,且易产生多种副This paper reports that hyperlipemia can be treated by acupuncture of Zusnli points. Zusanli points on both sides were needled on alternate days. After the needling sensation was felt, the needle was manipula- ted with even movements at 5 minute intervals and retained for 20 minu- tes. A daily session for 20 successive days constitued a therapeutic coures. After treatment the, the level of cholesterol(35 cases), triglyceride (10 cases) and β-lipoprotein(12 cases) in serum were maikedly reduced. The average levels of cholesterol, triglyceride and β-lipoprotein were reduced by 33.48mg %, 33.50mg % and 189.58mg % respectively. The effect of acu- puncture in reducing the serum lipids was better than the western medi- cine-Astromide and had no side effect. Also it could improve the physi- cal strength and sleep in the patients. But the mechanism of its efficacy remains unknown,939|0|0更新时间：2023-08-11
- 摘要：针灸治病的调整功能是多方面的,对免疫机能的调整是其中的一个方面,为了探讨针灸调整功能,本文从免疫学实验指标的变化,进行一些分析,现将所做细胞免疫和体液免疫两部分工作,整理报道如下: 一、针灸对细胞免疫的调整功能 1.淋巴细胞转化率测定:采用TC“199”液加PHA培养,收集细胞悬浮液,涂片染色,镜检计数,计算每个样品200个淋巴细胞,求出淋巴细胞转化率(％)。为了With long-term clinical practices and repeated experimental studies at hand in these Chinese special medical line, acupuncture and moxibus- tion could be in themselves giving rise to enhancing and strenghthening the functional capacity in immunal systen and adjusting immunicational functioning to a normal level, the treatment of acupuncture and moxibus- tion could fastly and evidently increase the lymphocytic transformation rate (p<0.001) within 6 to 8 hours of short duration, no matter what it is occurred in the aspects of either inflammatery or noninflammatory disea- ses, but some other stimulations and irritabilitics such as stabbing or so- me small scale operations in treatment could not whow any in effects at all. Acupuncture and moxibustion could also increase the high significan- ce level (p<0.001) so as to lower the the absolute value of lymhocyte and the E-rosette forming rate as well as the positive staining rate of lymphocyte esterase when it was indicated in the case of dysentery pati- ents and animal models (for example, Macaca mulatta and domestic do- gs). Besides these, acupuncture and moxibution could also reduce the Ni- troblue Tetrazolium Neutrophil Phagocytic index which had ever been in- crcasing sometime significatly and will approach the approximately nor- mal value, and meanwhile, they could be raised to a much higher signi- ficance level (p<0.05) on the side of bacterial phagocytism activity. As in the case of dysentery and othe inflammatory diseases, by frea- ting with the aid of acupuncture and moxibustion, we could increase the contents of serum IgG, IgA and IgM. In contrast, these would show a decreasing tendency if we treat these dysentery patients by using Gen- tamycin. And all the more, acupuncture and moxibustion would have the ability of raising the level of serum C_3, sometimes they are not only able to strengthen significantly the bactericidal power of plasma, but al- so they could be encouraged to find out the earlier formation of serum and stool antibody in the dysentery model as it was shown in Macaca mulatta four days ahead of routine schedule under titration, the serum antibody in acupuncture group was twofold as high as in that of control group, so that we can see that the functions in the reinforcement of bo- dily resistance as well as in the elimination of pathogens by treatment of acupuncture and moxibustion accomplished through the fulfilment of the immuno-competence in our experiment.726|0|0更新时间：2023-08-11
- 摘要：针灸治病的调整功能,已引起国内外学者的关注。为了探讨针灸对机体内在物质含量变化的调整功能,本文对针灸治疗的不同疾病患者血清蛋白比例的调整功能;对全血胆硷酯酶活性的调节作用;对血清无机盐类含量变化的调整功能等三方面,采用生化实验方法分别进行了分析,现将结果(限于篇数,实验方法从略)报道如下: 一、针灸治疗对血清蛋白比例调整功能的两种电泳行为分析: 在同一时期治疗的24例患者(包括炎症6例、神经痛10例及瘫痪8例),在针灸治疗前、治疗中期和治疗结束的三个阶We have examined the activity of cholinesterase before and after acu- puncture and moxibustion treatment in the experiment. it has been shown in our results that to the patients having painful feeling, the activity would be significantly lower than that of the normal person's value (p< 0.05). At the stage after the treatment for an hour, then one third of patients with pain syndrome would have released, the activity will obvious- ly be back to the normal value. In this way we might think that the ace- tylcholine would have been raised to a higher level because of the rea- son that the vigor (in chinese, we call it "Qi") would be gathered so much at the concentrated point that it might be in a position to explainit, on the one hand, and on the other hand, acupuncture and moxibustion could strengh the activity of cholinesterase and accomplish the function of regulating "xu"(deficiency) and "shi"(excess). The CTM theory has been confirmed by the author that the pharmacolo- gical quality of salts would show some functions in the way of harmoni- zing "Zang and Fu" (in chinese, the two terms means viscera altogether), "making health to human being", "weeding through the old to bring forth the new" and rectifying usefulness to renew the vigor (in chinese, it is pronounced as "Qi"), and so on and usually referred to as the essential substance derived from water and grain which can be used to maintain the activity of life's vigor and metabolism). With the examination of mineral salts in the modern medical science, we know that this is an important index in iudging the electrolytic balan- ce. It was discovered in our results that the salt material would be rai- sed from the lower level to something higher in the treatment of acupun- cture and moxibustion and vice versa, that is to say, the significance le- vel (p<0.05) would show that the values of these three elements, K, Na and P will increase and in the meantime, another two elements, Cl and Ca will in turn, drop down synchronously. These changing regularity shown above are consistant with the requirements of physiological balan- ce, thus demonstrating that acupuncture and moxibustion should possess an evident function of regulation so as to make the content of cineral salts with corresponding changes.703|0|0更新时间：2023-08-11
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