最新刊期
1989年第4期
- 摘要：穴位乃是身体上施行针灸的特定部位,简称为“穴”。它可“通经脉,均气血,蠲邪扶正”,是“处百病,调虚实”等的刺激点。也就是用于治疗疾病和增进健康的刺激点。同时它也是人体经络脏腑之气聚集和出入于体表的地方,与经络、脏腑、气、血均有密切关系。870|0|7更新时间：2023-08-11
- 摘要：我院继临床施行各种针刺麻醉手术5600余例之后,于一九八八年又着重研究危重、老年体弱、特殊疾病手术的针刺复合麻醉。分为针刺复合硬膜外麻醉(简称针药组)和硬膜外麻醉(简称对照组)各37例进行比较,取得较满意的效果,总结如下。836|0|0更新时间：2023-08-11
- 摘要：某一内脏有病,常在躯体的一定部位有所反应。而针灸躯体穴位时,对内脏疾病有较好的疗效。因而,祖国医学认为,躯体与内脏之间,存在一种特殊的关联,即所谓“躯体与内脏相关”的学说。本实验从神经学角度出发,切断动物的内脏迷走神经向中纤维;另一组动物切断脊髓前外侧索躯体向The experiment was divided into 2 groups. In one group, the animal's nodose ganglion of vagus nerve was taken out; In another group, the animal's half spinal cord was cut off. The results showed that both somatic ascending fibers and vagus nervous fibers all projected in solitary nucleus, commissural nucleus, trigeminal spinal nucleus and in nucleus medulla oblongalae centralis,i. e, these nuclei not only related to somatic nerves, but also related to splanchnic nerves (vagus nerve), which are considered to be foundation of correlation theory of soma and viscera.838|0|0更新时间：2023-08-11
- 摘要：我们曾报道,电针内关穴可抑制内脏大神经引起的大脑皮层诱发电位和大脑皮层后乙状回的内脏痛放电。由于腹腔内脏痛信息主要由内脏大神经C类纤维传导,因此,C类纤维引起的皮层诱发电位更能准确地反映内脏痛。本文拟用内脏大神经C类纤维传入引起的皮层诱发电位(C-CEP)作为内脏痛指标,观察电针内关穴及镇痛剂对内脏痛反应的影响。740|0|0更新时间：2023-08-11
- 摘要：尾核是锥体外系中与针刺镇痛有密切关系的一个结构,刺激尾核可产生镇痛作用,损毁尾核头部可减弱针刺镇痛,电刺激“合谷”时可在尾核记录到诱发电位,刺激人脑尾核头部能缓解晚期肿瘤病人的恶痛。本室曾证实,MRF是38 rabbits were anesthetized with chloralose and urethane. As soon as the animal recovered its consciousness it was immobilized with flaxedil and artificial respiration. The electrical activities of the nociceptive neurons were recorded by glass microelectrodes (tip 1-3μm) in the ranges P7-11 R2-3 HO+ 1-6, with the aid of a stereotaxic apparatus. 116 of the nociceptive units responded to noxious stimuli which applied to the peroneal nerve with a short train of pulses. Among them, 64 units (55%)responded by an increase in frequency of the discharge to noxious stimuli (pain-excition neuron, PEN). In contrast, there were 52 units (45%), which responded to noxious stimuli quite differently, by having a decrease in the frequency of the discharge (pain-inhibition neuron, PIN). Similar results were obtaingd by the stimulation of the head of caudate nucleus with the same train of pulses: an ex-citatory effect was observed in PEN. and an inhibitory effect in PIN. However,after electroacupuncture by penetrating acupoint "Hegu" or dolantin given intra-ven ously, under the same conditions used above. We again stimulated both the head of caudate nucleus, eliciting an inhibitory effect on PEN. And a reduction of inhibition or release from it on PIN. From the results presented, it indicated that head of caudate nucleus was connected with the modultion of the nociceptive neuronal activity in M. R. F. and was related to the effect of acupuncture. The effect of atropine on the head of caudate nucleus stimulation. The in-hibitory effect of the head of caudate nucleus on the nociceptive nucleus on thenociceptive discharges was diminished or cancelled by injection of atropine (0.3-0.5mg/kg i. v.). This suggested that the cholinergic system in the caudate nucleus was also involved in the pain impulses in M. R. F.869|0|0更新时间：2023-08-11
- 摘要：祖国医学对疾病的治疗历来主张“因时制宜”,强调时间因素在治疗疾病中的重要意义,“子午流注”和“灵龟八法”等时间针法更集中体现了针刺治疗与时间的密切关系。近年来,随着现代时间生物学和时间医学的兴起和迅速发展,时间因素对针刺疗效In the present study, rats were synchronized with light from 8:00 to 20:00,then darkness. Water and food were available ad libitum. The basical levels inmedulla oblongata plus pons, hypothalamus, hippocampus midbrain, striatum andcortex, and electroacupuncture influences on them were compared at four diffe-rent times of a day (5:00, 11:00, 17:00 and 23:00). It was found that: (1) The ba-sical level of LEK in the medulla oblongata plus pons at 11:00 was the highestamong the four times; (2) The LEK content incrased by 34.8% in the hypothala-mus and decreased by 21.4% in the cortex when EA was given at 5:00; TheLEK levels in the hypothalamus and the hippocampus increaed by 65.3% andby 37.0% respectively when EA at 11:00; The LEK level in the hippocampusincreased by 50.1% when EA at 17: 00; The hippocampus decreased by 29.8%when EA at 23:00. The results show that a circadian rhythm was evidente in the LEK levelof the rat medulla oblongata plus pons, also EA at diffeaent hours produced different effects on LEK contents in rat discrete brain regions. This provides experimental evidence for acupuncture treatment selecting hours clinically. Also,the physiological circadian variation and the influence of time factor on acupun-cture effects should be considered in study of acupuncture mechanism.887|0|2更新时间：2023-08-11
- 摘要：本实验室以往工作曾观察到,电解毁损大鼠一侧皮层体感区后,可削弱电针提高甩尾阈的作用。该结果提示,大脑皮层对脊髓水平痛反应有下行调节作用。但有工作报导,横断脊髓的大鼠,电针后甩尾阈同完整鼠相比,电针效应虽下降并达到统计学意义,但电针仍可使脊髓鼠的甩尾阈提高,只In this paper the effects of electroacupuncture on nociceptive responses were investigated after electrolytic lesion of unilateral somatosensory cortex on diffe-rent days. It was found that the tail flick latencies (TFL) e1icited by radiantheat was not obviously changed by EA (n=10, P>0.05) on the same day andthe next day after the somatosensosy cortex was injured, but the enhancementof TFL by EA was of statistical significance on the 7th day (n=9, p<0.05).These results indicate that the effect of EA analgesia was attenuated after lesionof the somatosensory cortex unilaterally. However, it could be recovered after aperiod of time. It is suggested that the somatosensory cortex is involved in thedescending modulation of nociceptive responses at the spinal level, although it maynot be the essential structure.854|0|0更新时间：2023-08-11
- 摘要：临床针麻手术有配合使用氯胺酮提高其效果,但也有持相反的意见。在我们以往的一些工作中主要是观察大鼠在清醒状态下的行为反应,因此一些必要的手术是在氯胺酮麻醉下完成的。由于氯胺酮的作用时间较短,动物可很快恢复,便于进行实验,但是否会影响到针刺镇痛作用的研究,这是个值得考虑的问题。有报导氯胺酮有拮抗There were different opinions about whether ketamine has an antagonisticeffect on electroacupuncture (EA) analgesia. The aim of this paper was to inve-stigate the effect of ketamine on EA. The rats were divided into three groups: 4mg/kg, 20mg/kg of ketamine in doses, and normal saline groups. Ketamine was injected peritoneally in dosage of 4mg/kg and 20mg/kg respectively. Tail flick latency (TFL) and vocalization threshold (VT) were taken as the indices of pain responses. Changqiang andYaoshu acupoints were selected for electroacupuncture. It was observed that the analgesia effects of EA were attenuated after in-jection of ketamine either in 4mg/kg group or 20mg/kg group. The results indicate that 4mg/kg or 20mg/kg ketamine in doses has anantagonistic effect on EA analgesia, suggesting that attention should be paid to the dosage when ketamine is used for EA analgesia.812|0|0更新时间：2023-08-11
- 摘要：休克是临床上常见的危重症,涉及医学各个学科。对于其发病机理的认识,长期以来也是学说不一,其中“细胞代谢障碍”的学说日益受到重视。多方面的研究表明,细胞在缺血缺氧时出现的能量代谢紊乱是细胞活力减低、坏死和最终各系统及脏器功能衰竭的恶性起步点。一些学者甚至提出“休克实际上是体内各器官细胞的急性The energy crisis has been considered to act a important role during shockrecent years. We all know the liver can supply for energy substrate when bodyis in an emergency condition. According to the theory of Traditional ChineseMedicine, Renzhong acupoint is a very important acu point to treat "Jue Zheng"(including shock). We divided 36 male rabbits into three groups randomly,they were normal, acupuncture and nonacupuncture. The normal control wasanesthetized only with sodium pentobarbital (35mg/kg). The acupuncture and non-acupuncture groups were operated under conscious with method of improvingwiggers(1950). After bleeding 20ml/kg, these animals were in shock. Then theacupuncture group was applied with acupuncture at "Renzhong" and the nonacup-uncture group was not during hemorrhagic shock. The samples of liver were ex-cised and stained using enzyme histochemical method. All of them were deter-mined with MPV-2 and Univar-SMSP. Two dehydrogenases (LDH and SDH) in hepatocytes were observed in this work. The results showed that the enzyme'sactivity in nonacupuncture both LDH and SDH were the weakest among threegroups (P<0.01 and P<0.05) But in acupuncture group, they were stronger than nonacupuncture group and near normal control. These suggest that acupun-cture at "Renzhong" acupoint can increase activity of LDH and SDH during hemorrhagic shock. It is useful to resistance shock in a certain degree.932|0|1更新时间：2023-08-11
- 摘要：临床上针刺治疗冠心病,在病人的心尖搏动图观察到:针刺可以降低舒张期终末压,并可改善心肌顺应性。在动物实验性心肌缺血性损伤中观察到针刺具有增加左室内压——压力变化上升速率(P-dp/dt),并使心肌纤维收缩成份缩短速度(VCE)等参数明显加快,表明针刺可以增强心肌收缩力,改善心肌纤维收缩成份。为了探讨心In order to explore the effect of electroacupuncture on myocardial contracti-bility in the ischemic area, a medical Silicon tube with Saturated Copper Sulf-ate was used as length gauge and set at 5mm below the ligated marginalis andparalleled with blood vessel. The signals of the length and the pumping functionwere transmitted into the polygraph and the signals of the left intraventricularpressure (LVP) and the segment length (L) were conveyed into the oscilloscopeto display the LVP-L vector loop. Electroacupuncture was applied bilaterally on Neiguan points with electricalimpulses of strength 5 volts. The arterie coronaria was ligated for 20 min andthen loosened. electro-acupuncture was performed and lasted 20 min. Imbedd-ed the needle for 30 min, then ligated at the original position and never loose-ned again; 15 min later, the electroacupuncture was performed for the secondtime, lasting 20 min, then the needle was with drawn and observed for 15min. The Epicardial ECG was used as the standard to judge the degree of themyocardial ischemic injury. A comparison was made between the parametersdetermined 15 min after ligation and all the procedures after electroacupunture.There were 15 dogs in the electroacupuncture group and 15 in the control group. 1. The mean amplitute of segment length of the myocardium was 23mmbefore ligation. 15 min after ligation, it slightly decreased in the electroacupu-ncture gronp while slightly increased in the control group. There was no obviousdifference in the duration of the amplitute between the two groups. The twoparameters determined before ligation and 15 min later, were not statisticallysignificant between the two groups (P>0.1). 2, In the electroacupuncture group, the amplitute of the myocardial segment length determined 15 min after ligation was 22.65±11.03mm. There was nostatistical difference between the two gorups (P>0.1). It was slightly decreasedin the electroacupuncture group during imbedding the needle after performing electroacupuncture, and slightly increased in the three procedures after the second ligation. Comparing it with that determined 15 min after ligation, there was no difference (P>0.1). In the control group, although the ligation was loosened 20 min after ligation, the amplitute declined gradually. It changed from positive to negtive. It was -43.87±17.87mm after withdraw of the needle, which correspo-nded to those of the procedures of performing electroacupuncture, imbedding needle, the second ligation, the second electroacupuncture and the procedure after withdrawing the needle. There was statistical difference compared with that determined 15min after ligation (P<0.05). In the electroacupuncture group,there was no great change in the amplitute of the myocardial sogment length,while in the control group, it declined gradually. There was statistical difference between the two groups (P<0.05). But there was no statistical difference in the duration of the amplitute between the two groups. 3. Opposite waveform of the myocardial segment length appeared at 4 dogsfor each group after ligation, taking 26.67% respectively. After withdrawing theneedle, 7 dogs in the control group showed opposite waveform, taking 46.67%, while in the electroacupuncture group, the porcentage was 26.67%. The wave of one dog in the electroacupuncture group sometimes changed from opposite to positive, and sometimes from positive to opposite. 4. Observation of LVP-L vector loop: The rhombic figure of the LVP-L vector loop changed its original clockwise direction to counterclockwise direction after ligation, and the typical ischemic figure "8" appeared, which corresponded to the opposite waveform of the myo-cardial segment length appeared after ligation and indicated that the myocardium in the ischemic area become soft and opposite activity. The LVP-L vector loop for which the opposite waveform did not appear showd the figure that the length increased mainly and the width secondarily. The results described above demonstrates that electroacupuncture may improve and protect the myocardium of ischemic area, increase its tension, strengthen its contractibility, inhibit or reduce the myocardial protrusion in the ischemic area during systole, which is beneficial to the improvement of the pumping function of the heart.1139|0|0更新时间：2023-08-11
- 摘要：艾灸具有“温阳通络,扶正强壮”的功效,是一种兼有多种治疗和保健作用的医疗方法,自古以来就广泛流传于民间,并在历代医书上都有记载。随着人类对疾病认识的不断深入,艾灸在临床上的应用也越来越广泛,涉及内、外、妇、儿、皮肤和五官等多个学科,疗效逐步提高。近年来,有人试验用艾灸治疗甲亢和糖尿病患者,取得了一定The effects of moxibustion at "Zusanli" acupoint on serum endocrine hormo-nes of male Wistar rats were studied by measured serum values of TSH, T_3,T_4, FSH, LH, testosterone and insulin with radioimmunoassay, 40 male ratswere randomly divided into two groups, experiment group and control group, 20rats each group. In the experiment group, the animals were given a moxibustionat "Zusanli" acupoints of both sides of rats 8:00--9:00 am, 10min/side per dayfor 7 days. The control group was given notaing. All of both groups werekilled and got serum at same time. The results indicate that the moxibustioncan increase significantly serum value of insulin (p<0.01) and decrease promine-ntly serum value of T_4 (p<0.01), but no marked difference was found in FSH,LH, testosterone, TSH and T_3. It is suggest that the raise of insulin may haverelations with the effects of the moxibustion on neuro-endocrine system andimproving microcirculation of pancreas gland, and that the drop of T_4 may becaused by the moxibustion to inhibite the function of thyroid glane.947|0|1更新时间：2023-08-11
- 摘要：本实验室曾经报告针刺“膻中”穴可使授乳期大鼠及非泌乳鼠血浆催乳素水平明显升高。已知腺垂体催乳素的分泌受下丘脑释放的神经肽以及若干中枢递质的调控,对针刺引起催乳素分泌增加的效应中可能的中枢机制,特别是与某些神经递质间的关系尚未见有研究报告。本文应用中枢递质激动剂,拮抗剂,生物合成抑制剂等,着重观察了儿茶酚胺及r-氨基丁酸递质系统在针效中的可能作用,发现:电针致非泌乳鼠催乳素分泌增加的中枢机制可能与电针刺激拮抗了下丘脑多巴胺系统活性有密切关系;去甲肾上腺素系统在针效中未见有明显作用;r-氨基丁酸递质有可能参与针刺效应,但还需进一步研究。该针刺效应与其它中枢递质(如5-羟色胺,内源性鸦片类物质,组织胺)的关系,目前正在研究之中。869|0|0更新时间：2023-08-11
- 摘要：业已证明:P物质(SP)系初级伤害性传入纤维末梢所释放,与皮肤痛觉的传导有关,参与痛觉调制。曾有报导指出:人穴位区皮肤的肥大细胞明显多于非六区,并见人、小鼠穴区皮肤内肥大细胞与神经轴突形成联接,且肥大细胞中含SP颗粒,针刺后肥大细胞脱颗粒。那么,经六皮Numerous reports indicated that sucstance p (SP) was a neurotransmitterinvolved in nociception, it also had analgesic effects in the most part of the central nervous system of all mammals, including man. The numbers of mast cell inhuman's some acupoint tissue were much higner than the non-acupoint tissue, therewas connection beuween the nerves and mast cells which contained SP particles.Therefore, it is worth studying the change of the concentration of SP in the skinand plasma of rats during the process of acupuncture analgesia. 55 rats were divided into 8 groups; (1) Control group; (2) Heat stimulationgroup; (3) Electro-acupuncture group; (4) Morphine group; (5) Naloxone (NX)group; (6) NX plus electro-acupuncture group; (7) Non-acupoint electro-acupu-ncture group; (8) Normal saline solution group. The concentration of SP in the"channel"、"acupoint" skin and plasma of rats were determined by radioimmunoa-ssay (RIA). The results show that after acupuncture, the tail-flick thresholdis increased, the concentration of SP in the skin and plasma is decreased signifi-cantly and the effect of electro-acupuncture is abolished by naloxone (i. p). Therdsults suggest that SP is a transmitter relating to skin nociception and involves the process of pain regulation. Electro-acupuncture can inhibit SP release fromthe skin and the plasma of rats. There is a functional interaction between SPand endorphin in the effects of electro-acupuncture. That is the SP decrased indu-ced by electro-acupuncture may depend upon the function of opiate receptors,965|0|0更新时间：2023-08-11
- 摘要：脊神经节是体躯一级感觉神经元胞体集积区,是研究一级感觉传入神经化学性质的一个重要部位。我室曾用组织化学的方法发现脊神经节内含有乙酰胆碱酯酶(AchE),本文将以生化的方法研究电针和切断后根后脊神经节内Ach含量及脊神经节和脊髓后角内AchE活性的变化,旨在探讨外周乙酰胆碱(Ach)与针感一级传入的关系。1059|0|2更新时间：2023-08-11
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