最新刊期

    1989年第Z1期
    • 猫小脑皮层的慢痛反应

      吴杰, 陈培熹
      1989(Z1)
      摘要:本文进一步观察,选择性C类纤维传入能否到达小脑皮层引起特异的诱发电位,吗啡和纳洛酮对其影响。实验用猫,在氯醛糖麻醉和三碘季铵酚制动下进行。用1.2V强度刺激隐神经,只引起A类纤维传入时,在对侧小脑皮层出现潜伏期为11.8±3.5ms的A类诱发电位(A-CEP)。用30V强度刺激,同时引起A和C类纤维传入时,皮层出现潜伏期为10.6±3.3ms的AC类诱发电位(AC-CEP),波形类似A-CEP,两者差异无显著性。用极化电流选择性阻断A类纤维传入后,强刺激只引起C类纤维传入时,在小脑皮层出现潜伏期为134.2±18.4ms的C类诱发电位(C-CEP)。降低刺激强度于C类阈下A类阈上时,C-CEP立即消失。  
        
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    • 1989(Z1): 2-3.
      摘要:In the present investigation, we observed whether the C-fiber input insaphenous nerve could project to the cerebellar cortex and elicit a characteri-stic evoked potential and the effect of the morphine and Naloxone on thepotential.  
        
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    • 电针对小脑皮层慢痛反应的影响

      吴杰, 陈培熹
      1989(Z1)
      摘要:本文以C类神经纤维传入引起的小脑皮层平均诱发电位作为慢痛反应指标,观察电针足三里穴对其影响,以探讨小脑皮层与电针抑制慢病的关系。一、电针足三里穴对小脑C-CEP的影响实验用猫,在氯醛糖麻醉和三碘季铵酚制动下进行。以10V强度,0.2ms波宽,5Hz频率的方波电脉冲电针同侧足三里穴1分钟,C-CEP受到明显抑制,主要表现为波幅减小。以电针前C-CEP的波幅为100%,电针后1、5、10和25分钟时波幅分别为63.2±18.1%(P<0.05,n=6)、101.2±24.8%(P>0.05)、88.9±27.1%(P>0.05)和97.4±10.0%(P>0.05)。同时记录的AC-CEP波幅无明显变化。  
        
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    • 1989(Z1)
      摘要:In Ihe present investigation, the cerebellar cortical average evoked poten-tial (C-CEP) elicited by C-fiber input was regarded as an index of the responseto slow pain, the effects of EA at "zusanli" point on C-CEP were observed. 1. Effect of EA at "zusanli" point on the cerebellar C-CEP Experimeets were performed on cats under chloralose anaesthesia andimmobilized by Flaxedil. The amplitude of C-CEP was inhibited obviouslyafter EA at the strength of 10V, the duration of 0.2ms, and frequency of5Hz at the ipsilateral "zusanli" point. At 1, 5, 10 and 25 minutes after EA,the amplitude of C-CEP was 63.2±18.1% of that before EA (P<0.05, n=6), 101.2±24.8% (P>0.05), 88.9±27.1% (P>0.05) and 97.4±10.0% (P>0.05) respectively, but the amplitude of AC-CEP had no significant change.  
        
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    • 大脑皮层在针刺镇痛中的下行调节机理

      徐维, 陈正秋, 林郁
      1989(Z1)
      摘要:针刺穴位治疗痛症具有显著疗效早被临床实践证明。近年来,有关针刺镇痛机理已有所阐明,但是,大脑皮层是否参与疼痛下行调节报导并不多见。本实验室在猫上,用玻璃微电极细胞外记录丘脑髓板内核群(束旁核Pf,中央核CM,中央外侧核CL)神经元放电的方法,观察电刺激大脑皮层体感Ⅱ区(SⅡ区)或皮层局部给药对上述核团的伤害性反应及针刺效应的影响。以电脉冲刺激腓浅神经作为伤害性刺激,选用“足三里”和“环跳”二穴,结果如下:  
        
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    • 1989(Z1): 6-7.
      摘要:It has already been proved by clinical practice that some pain syndromstreated with acupuncture could be relieved. There were only a few reports onthe involvement of the cerebral cortex in descending modulation of acupunctureanalgesia(AA), although the mechanisms of AA have been elucidated to someextent recently.  
        
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    • 施婷, 徐维
      1989(Z1): 7-8.
      摘要:本文采用玻璃微电极细胞外记录神经元放电的方法,在SⅡ局部施用GABA的条件下,观察电针“环跳”、“阳陵泉”二穴对PAG神经元伤害性反应的影响。实验用猫32只,在清醒麻痹及人工呼吸的状态下记录PAG的神经元电活动,观察到单纯电针上述二穴可抑制PAG神经元的伤害性反应。在SⅡ局部施用GABA,观察了另一组PAG神经元伤害性反应在电针后的变化。结果此组15例神经元伤害性反应变化率均数在电针前后的差别无统计学意义(P>0.05)。SⅡ局部用生理盐水组的14例神经元伤害性反应在停电针后0—10分钟都受到抑制(P<0.01)。电针穴位后单纯电针组与SⅡ给生理盐水组之间无显著差别(P>0.05):SⅡ给GABA组与SⅡ给生理盐水组之间差别显著或非常显著(P<0.05或P<0.01);SⅡ给GABA组与单纯电针组之间差别也非常显著(P<0.01)。  
        
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    • 1989(Z1)
      摘要:In this study we investigated that whether the corticofugal modulation fromSH is involved in the acupuncture effects on PAG. It was carried out on 32restrained adult cats. The unit activities of PAG were recorded by glass microelectrodes. Elect-rical stimulation on the right superficial peroneal nerve was taken as thenoxious stimulation. The results showed that electroacupuncture (EA) atHuantiao (G 30) and Yanglingquan (G 34) points could inhibited the nocice-ptive responses of PAG neurons, i.e, the changes of the firing rates inducedby the noxious stimulation were lessened 0-12.5 minusts after ceasing EA(n=15, P<0.01). When a piece of filter paper damped with 0.5M GABA was  
        
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    • 王葆庆, 陈培熹
      1989(Z1)
      摘要:本文以体感皮层诱发电位(C-CEP)为指标,观察中脑导水管周围灰质(PAG)对慢痛反应的影响,为探讨慢痛的调制提供资料。实验用猫,在氯醛糖麻醉和三碘季铵酚制动下进行。用极化电流阻断A类纤维传导后,电刺激腓浅神经,引起选择性C类纤维传入。引导同侧脊髓背表面电位(C-SSP)和对侧大脑体感皮层诱发电位(C-CEP),叠加平均记录。以200ms短串电脉冲刺激PAG。  
        
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    • 1989(Z1): 9-10.
      摘要:In this artical the effect of stimulating PAG on C-CEP was observed in order to provide some data for the research of slow pain modulation. Experiments were performed on cats under choloralose anaesthesis andimmobitized by gallamine triethiodide. After blocking A-fibers input by anodalcurrent the superficial peroneal nerve was stimulated with strong electricalpulse, and the C-fiber input was elicited selectively. The evoked potentialswere recorded on the back surface of ipsilateral spinal cord (C-SSP) andcontralateral cerebral somatosensory area (C-CEP). PAG was stimulated withshort electrial pulse.  
        
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    • 大脑皮层联合区在电针抑制体感皮层慢痛反应中的作用

      冯鉴强, 陈培熹
      1989(Z1): 10-11.
      摘要:本文以隐神经C类纤维传入在体感皮层(SI)引起的诱发电位(C-CEP)作为慢痛反应的指标,观察电针“足三里”穴对C-CEP的影响及大脑皮层前外侧回联合区(ALA)在其中的作用。实验用猫,在氯醛糖和三碘季铵酚处理下进行。电针“足三里”穴对C-CEP有明显的抑制作用,包括早期和晚期抑制两个过程。(1)早期抑制,电针后立即出现,持续时间短,2分钟内C-CEP的幅值较快地恢复;(2)晚期抑制,电针后4分钟逐渐出现,10—12分钟时抑制作用最大,持续较长时间,20分钟后恢复至接近电针前水平。  
        
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    • 1989(Z1): 11-12.
      摘要:Experiments were performed on cats under the treatments of chloraloseand flexedil. The cortical evoked potentials (C-CEP) recorded in primarysomatosensory cortex(SI), which were elicited by C-fiber inputs of sapheneousnerve, were used as an index of slow pain. The effect of electro-acupuncture(EA) of "Zusanli" point on C-CEP and role of cerebral anterior laterialassociation area(ALA) in this effect were observed.  
        
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    • 刺激体感Ⅰ区对海马痛单位放电的影响以及与针效的关系

      曾玲, 卢树斌, 谢惠明, 张均明, 苏承华, 刘荫仁
      1989(Z1)
      摘要:本文探讨体感Ⅰ区(SⅠ)对海马痛单位放电的影响及与针效的关系。共用家兔53只,把玻璃微电极推进海马部位引导痛单位放电,用同心园电极刺激SⅠ区,普通电极刺激腓神经,BT-701电针麻仪电针两侧“内关”透“外关”。静脉注射镇痛剂(杜冷丁5毫克/公斤体重)。观察分析对海马痛单位放电的影响。结果如下;共引导海马放电单位246个,经监定痛兴奋单位73/246个(占21.6%),痛抑制单位20/246个(占8.13%),在自发放电的背景上分别观察各项刺激对痛放电的影响。一、痛兴奋单位:1.刺激SⅠ区或腓神经时放电频率增加,时程延长。同时刺激SⅠ区和腓神经时痛放电增加较单独刺激腓神经时明显表现了兴奋的协同作用。2.停电针后15分钟刺激SⅠ区或腓神经时,痛兴奋单位放电抑制,频率减少或暂停放电。同时刺激SⅠ区和腓神经时,放电抑制程度较单独刺激腓神经更显著。共观察8个单位电针效率达87.5%。  
        
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    • 1989(Z1): 13-14.
      摘要:The purose of thes study was to research the effect of the somatosensoryarea Ⅰ on pain unit of hippocampal and its relationship effect of acupuncture. Result: Total 246 dischage units in hippocampal were tested 73 were painexcitatory units, 26 were pain inhibitory units. 1. pain excitatory units (1) When stimulation somatosensory area Ⅰ or nerve peronaeus communisalone, the dischages frequency of pain units were increased and dischagescourse prolong. If simultaneous stimulation both the dischages frequendy andtime course were more increase than stimulation nerve peronaeus communisalone.  
        
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    • 卢树斌, 曾玲, 谢惠明, 苏承华, 高玉林, 刘荫仁
      1989(Z1)
      摘要:在53只家兔进行了实验观察用玻璃微电极在杏仁核 A。-。L。-。H-。--,范围内记录神经元单位放电,以电刺激脏神经及有齿镊夹耳壳为伤害性刺激,共观察461个杏仁核单位放电,其中痛单位216个/461(占47%),病无关单位242个/461(占52.3%),双相单位3个/461(占0.7%)。在 216个痛单位中,给予伤害性刺激引起放电数目减少或暂停的痛抑制单位 112个/216(占52%;放电数目增多的痛兴奋单位104个/216(占48%)。采用同心园电极,以短串脉冲刺激 S!前肢代表区,观察到刺激 SI区可以影响杏仁核痛单位的电活动。  
        
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    • 1989(Z1): 15-16.
      摘要:53 rabbits were used as experimental animals. Electrical activity of theneurons in areas A_(0-2) L_(3-5) and H_(2-7) of the amygdala were recorded byglaos mscroelectrode. Electrode. Electrical stimulation of the peroneal nerveand pinching the rabbit's ear were used as nociceptive stimulations, Electricaldischarges of 461 amygdala neurons were observed, among which there were216 (47%) pain sensation neurons, 242 (52.3%) neurons not related to pain,and 3 (0.7%) double phase neurons (i.e. neurone which began with excitationor inhibition followed by inhibition or excitation). Among the pain sensationneurons there were 112 (52%) pain inhibitory neurons in which nociceptivestimulation caused a decrease or even an abolishment of the electrical discha-rges, and there were 104 (48%) pain excitatory neurons in which an increasein electrical discharges were observed.  
        
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    • 曾玲, 卢树斌, 谢惠明, 张均明, 苏承华, 刘荫仁
      1989(Z1)
      摘要:实验用健康家兔55只,把玻璃微电极插入丘脑腹后外侧核(VTL)引导单位放电,用同心园电极刺激体感Ⅰ区(SⅠ区),普通电极刺激腓神经,电针两侧“内关”透“外关”穴。分别观察对放电单位的影响。实验结果如下:共引导(VPL)放电单位380个,其中仅对伤害性刺激有反应的单位127/380个(占33.4%),分为痛兴奋单位84/380个(占22.1%)和痛抑制单位43/380个(占11.3)  
        
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    • 1989(Z1): 17-18.
      摘要:Experiment were parformed on 55 rabbits. The experiment results as follows: Total 380 dischage units of ventropost-erior lateral were recorde, 127 units were found to be responsive to noxiusstimulate, among which 84 units showed excifatory effect and 43 units inhibi-tory effect. 1. The effect of electroacupuncture on pain excitatory units (1) Before electroacupuncture: Stimulated nerve peronaeus communis orstimulated SI area alone or simultaneous stimulated nerve peronaeus and SI areapain units excitatory dischhges frequence were increased and dischages coursewere prolonged. During simultaneous stimulated nerve peronacus and SI areaoccur pain units excitatory discharges increase more obvious than stimulatednerve peronaeus alone.  
        
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    • 黄忠致, 韩冠钰, 高玉林
      1989(Z1)
      摘要:为了研究Ca(2+)是否参与大脑皮层体感Ⅰ区对外周皮肤痛觉及针刺镇痛的调制作用。以伤害性刺激引起回避性操作式条件反射作为痛指标,在三只清醒、可活动的猕猴上观察了SI区皮层内注射微量氯化钙对外周皮肤痛阈和针刺镇痛的影响。其结果如下:(1)SⅠ区下肢代表区皮层内注射氯化钙的26次实验中,22次引起对侧相应皮肤感受野痛阈明显升高(P<0.01或P<0.05),一般痛阈在氯化钙皮层内注射5分钟后即开始升高,并持续升高30分钟,甚至长达1.5小时之久。(2)皮层内注射氯化钙的剂量不同,痛阈的升高明显程度也不同。三种剂量中以皮层内注射每公斤50微克皮肤痛阈升高最为显著,其次为每公斤25微  
        
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    • 1989(Z1)
      摘要:In order to study whether calcium ions in SI area take part in moduratingpain sensation of peripheral skin and acupuncture analgesia. Experiments wereperformed on 6 awake monkeys (Macaca Mulatta). Operant conditioningelicited by noxious stimulation was taken as an indicator of pain. Influenceof intracortical microinjection of CaCl_2 in SI area on pain threshold of theperipheral skin and acupuncture analgesia was observed. The results obtainedwere as follows. (I) In 35 out of 39 tests, pain threshold of the peripheral  
        
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    • 电针对环磷酸腺苷所致皮层痫样电活动的抑制作用

      娄之聪
      1989(Z1)
      摘要:家兔侧脑室注入cAMP(100μg/100μl)后,诱发皮层产生癫痫样波,此痫样发作波可被电针双侧“足三里”穴明显地抑制。 10只家兔侧脑室注入cAMP(未电针组),各皮层区间断出现高幅、高频痫样发作波,波型以棘、尖波和棘尖、棘慢波为主,呈现棘波节律的同步化放电。各波振幅较给AMP前明显增高,尤以α、β波更为显著。给cAMP 20分时发作波时范围是0.55~1.51秒,40分时0.48~1.08秒。  
        
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    • 1989(Z1): 20-21.
      摘要:In conscious rabbits, injection of cAMP (100μg in 100μl, icv) elicitedhigh-amplitude and high-frequency epileptiform seizure pattern of ECoG. The(pileptic waves were inhibited by electro-acupuncturing bilateral "Zusuanli"points. During and after the cessation of electro-acupuncture the frequency,  
        
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    • 吴钢, 姜建伟, 吴根诚, 曹小定
      1989(Z1)
      摘要:我们在兔耳钾离子透入测痛模型上观察到左旋四氢巴马汀(L-tetrahydropalmatine,L-THP)可加强电针的镇痛作用。本工作采用兔大脑皮层牙髓诱发电位(tooth pulpvoked potentials, TPEPs)为痛的指标,拟在感觉水平上进一步了解L-THP与电针镇痛的协同关系。兔大脑皮层TPEPs波形成份与痛的关系;实验在1%氯醛糖和10%尔拉坦浅麻醉下进行。电刺激牙髓在对侧大脑皮层感觉运动区引导出的TPEPs主要的成份为P_1、N_1、P_2、N_2等波形。通过改变牙髓电刺激强度,静注无镇痛作用的中枢抑制剂安定(1mg/kg)和镇痛剂杜冷丁(5mg/kg)三者对TPEPs波形成份影响作用的观察,了解到波峰潜伏期约为TPEPs 66ms的P_2波与痛的关系较大。  
        
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    • 1989(Z1): 22-23.
      摘要:Previously we found that L-tetrahydropalmatine (L-THP) could enhancethe inhibitory effect of electroacupuncture (EA) on the defense behaviourresponse to the noxious stimulation of the rabbit's ear skin by potassium ionto-phoretic dolorimetry. In this paper, the effects of L-THP and EA on evokedcortical potentials to stimulation of tooth pulp were observed to study thesynergism botween L-THP and EA analgesia at sense level.  
        
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    • 陈助华, 张彤, 陈培熹
      1989(Z1)
      摘要:研究细胞放电的痛反应及电针效应,多以非时锁反应(N-TLR)为指标,也有用时锁反应(TLR)为指标,两者反映角度不完全相同。本文用微机结合随机点理论和数字信号处理方法对伤害性刺激猫的外周神经(腓浅或内脏大神经)诱发对侧体感皮层73个细胞放电(P-ED)的时锁和非时锁反应进行定量分析,互相比较。N-TLR以放电间隔(ISI)均值函数表示,TLR以刺激和反应的标准互协方差函数(NCCVF)表示。 1.非时锁反应分析 73例P-ED中,15例的ISI均值函数显著升高,为抑制型,30例显著降低为兴奋型,28例无显著变化为无反应型。  
        
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    • 1989(Z1): 24-25.
      摘要:The non-time-lock response(N-TLR) is regarded as an index of response topain and acupuncture in most study on unit discharge at present; the timelockresponse(TLR) is regarded as an index as well, but the meanings of NTLR andTLR are somewhat different. In the present study, the N-TLR and TLE of73 unit discharges in somatosensory cortex evoked by nociceptive stimulationof peripheral nerve (superfical peroneal or splanchnic nerve) (P-ED) wereanalysed quantitatively with micro-computer using the method of stochasticpoint process for signal analysis and compared each other. N-TLR was shownby interspike interval mean function (ISIMF); TLR was shown by normalizedcrosscovariance function (NCCVF) reflecting the relationship between stimula-tion and response.  
        
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    • 电针和吗啡对痛敏单位放电的时锁和非时锁反应的影响

      陈助华, 张彤, 陈培熹
      1989(Z1)
      摘要:实验用猫,在氯醛糖浅麻和三碘季铵酚肌松下观察,用微机结合随机点理论和数字信号处理方法对伤害性刺激腓浅神经(P-ED)诱发体感皮层单位放电进行定量分析,以探讨吗啡及电针(EA)对痛敏单位放电的非时锁反应(N-TLR)和时锁反应(TLR)的影响。以放电间隔均值函数(ISIMF)反映非时锁反应。以放电与刺激的标准互协方基函数(NCCVF)分析时锁反应。 1.从ISIMF图看,伤害性刺激腓浅神经引起ISI减小反应,电针“脊中”穴8分钟后刺激神经引起ISI增大,停电针后15分钟刺激神经又引起ISI减小。注射吗啡(300mg/kg)后4分钟,刺激腓浅神经引起的ISI减小反应不明显;注射后7分钟刺激神经引起ISI增大;注射后12分钟刺激神经又引起ISI减小。  
        
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    • 1989(Z1): 26-27.
      摘要:Experiments were performed on cats under chloralose and flaxedil. Evokedunit discharges recorded in contralateral somato-sensory cortex to noxiousstimulating superficial peroneal nerve (P-ED) were analysed quantitativelywith micro-computer using the method of stochastic point process for signalanalysis in order to study the effects of electro-acupuncture(EA)and morphineon non-time-lock response(N-TLR) and time-lock response (TLR) of nociceptiveunit discharges. N-TLR was shown by interspike interval mean function(ISIMF).TLR was shown by normalized cross-covariance function (NCCVF) reflectingthe relationship between stimulation and response. The results were testedstatistically.  
        
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    • 中缝大核的痛负反馈调制机制在电针镇痛中的作用

      刘乡
      1989(Z1): 27-28.
      摘要:我们近十几年对脑内镇痛系统的主要下行抑制起源部位之一延脑中缝大核(NRM)在针刺镇痛中的作用,进行了较为系统的研究,主要结果如下: 一、实验用大鼠,细胞外记录NRM神经元放电,选择对伤害性刺激发生反应的神经元进行观察。这些神经元的自发放电频率多为0.5~20次/秒,个别在20次/秒以上或无自发放电。它们对非伤害性自然刺激(如触毛)或弱电刺激一般不发生反应,或仅有轻微的增频反应且很快适应,但对伤害性刺激(如针刺或钳夹皮肤)或强电刺激。则多发生兴奋性(增频)或抑制性(减频)反应。兴奋型神经元自发放电频率较低,而抑制型神经元的频率较高。我们还意外地发现了3例兴奋抑制转化型神经元,而且看到这种转化与其背景放电的频率有关,当自发放电频率较低时对伤害性刺激的反应为兴奋性的,而当频率升高时,则转化为抑制性反应。  
        
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    • 1989(Z1): 28-30.
      摘要:In recent years I am interested in the role of nucleus raphe magnes (NRM)in acupuncture analgesia, NRM is the one of origins of important descendinginhibitory systems inclueded in the intrinsic anatgesic systems in brain, and wegave more systematic study on the question. The primary results are asfollows: 1. Experiments were perfored on male rats, unit discharges of NRMwere recorded extracellularly with glass electrode. The neurons responed tonoxious stimulation were chosen to observe analgesia of EA. The spontaneousfiring rates of NRM neurons were about 0.5-20Hz, a few of them over 20Hzor have no any discharges. NRM neurons have not often responses to non-noxious stimulation(to brush hair) or only have a light responses and adapt-ation appeared fast. But responses of them to noxious stimulation (to clampor to prick skin) or electrostimulation (20V) were obviously displayed with  
        
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    • 刺激大鼠大脑皮层SⅡ区对中缝大核神经元活动的影响

      蒋旻春, 刘乡
      1989(Z1): 30-31.
      摘要:实验用大白鼠体重200~350克,玻璃微电极细胞外记录中缝大核(NRM)神经元放电。经埋置电极刺激双侧SⅡ,双侧“足三里”电针时间5分钟,尾尖刺激作为痛刺激。实验分电刺激SⅡ组和电针“足三里”组,两组在同一个神经元上进行,记录两次伤害性刺激后NRM神经元的反应,以其均数作为自身对照,尔后电刺激SⅡ或者电针“足三里”,观查该神经元30分钟内对伤害性刺激的反应及自发放电的变化。两组实验共观察了10个兴奋型NRM神经元。可以看到:刺激SⅡ能够不同程度地激活这些神经元,使其自发放电增高,伤害性反应减弱。经统计学处理,自发放电增高在0~  
        
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    • 1989(Z1)
      摘要:Rats (200-350g) were used in this experiment. The unit discharges of NRMneurons were extracellularly recorded with glass microelectrode. The bilateralSII was stimulated by fixed electrodes. EA of "Zusanli"was applied for 5 mi-nutes. Electrostimulation of tail was used as a noxious stimulus. The expe-riment was divided into two groups, one is stimulation of SII and another EAof "Zusanli", both were performed at the same NRM neurons. It was foundthat stimulation of SII could activate the excitatory neurons in NRM (n=10),significantly increasing their spontaneous discharges and decreasing their nocice-ptive responses in 0-20 minutes (P<0.05-0.001). Similar results were observedin the group of EA. After EA, increase of their spontaneous discharges in 0-10minutes and at 20th minute, and decrease of their nociceptive responses in 0-25minutes were statistically significant (P<0.05-0.001).  
        
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    • 刺激鼠大脑皮层感觉运动区对中缝大核神经元活动的影响

      邹挺, 刘乡
      1989(Z1)
      摘要:本实验目的在于探讨SM区的痛觉调制作用是否与NRM的下行抑制有关。实验用大白鼠,体重200~350克,雌雄不拘,玻璃微电极细胞外记录NRM的单位放电。在鼠尾尖1/3处插入2支毫针进行伤害性刺激;在右顶叶SM区,部分动物同时在右额叶运动区(M区)用双极银球电极进行皮层表面刺激。结果如下: 一、在14只动物上记录了55个NRM神经元,对伤害性刺激发生兴奋型反应的29个,抑制型反应的12个,无反应的14个;对10个单位观察了单个或2~10个短串方波刺激SM和M区的效应,45个单位仅观察了刺激SM区的效应,多数单位无反应,少数有兴奋性反应,而发生抑制性反应的很少。实验中发现4个兴奋型神经元和1个抑制型神经元,SM区刺激无反应,但在停刺激后一段时间内抑制伤害性反应。  
        
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    • 1989(Z1): 32-33.
      摘要:The purpose of the work was to study whether SM was involved in the descending inhibitory effects of NRM on nociceptive response. The cxperiments were carried out on rats. Results were as follows: 1. The influence of single and short train stimulating SM or motor areal(MI) on 55 neurons of NRM were observed. Of 55 neurons, 29 units showedthe excitatory response to noxious stimulation, 12 units the inhibitory respon-se and 14 units without obvious changes. During stimulation of SM with sin-gle and short train pulse for 55 neurons or MI for 10 neurons, a few unitswere activated (10/55 or 2/10), only one unit 'were inhibited, most of themshowed no obvious changes.  
        
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    • 蒋旻春, 刘乡
      1989(Z1): 33-34.
      摘要:实验用大白鼠体重200~350克,玻璃微电极细胞外记录NRM神经元的自发放电及串脉冲尾尖刺激后的反应。电解损毁双侧SⅡ。双侧“足三里”电针,时间5分钟。实验分两组进行,一组在SⅡ完整条件下电针“足三里”,另一组则是在SⅡ毁损后电针“足三里”,实验中记录两次伤害性刺激后NRM神经元的反应,以其均数作为自身对照,尔后电针“足三里”,观察此后该神经元30分钟内伤害性反应及自发放电的变化。 SⅡ完整组观察了10个兴奋型NRM神经元,SⅡ毁损组为17个,其中有3个与SⅡ完整组为同神经元。看到在SⅡ完整组,电针“足三里”可明显增加NRM兴奋型神经元的自发放电,并使其伤害性反应减弱。统计学处理表明:自发放电的增加在0~10及20分钟有统计学意义(P<0.05~0.001)。伤害性反应减小在0~25分钟有统计学意义(P<0.01~  
        
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    • 1989(Z1)
      摘要:This work was to study effect of electroacupuncture(EA) of "Zusanli" onneurons of NRM after lesion of SII. Rats(200-350g) were used in the experiment. The unit discharges of NRMneurons were extrocellularly recorded with glass microelectrode. The excitatory neurons of NRM were chosen and divided into two groups,one of them(n=10) was control before lesion of bilateral SII and another (n=17) after lesion, three neurons of this group were also observed in the formergroup.  
        
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    • 邹挺, 刘乡
      1989(Z1)
      摘要:实验用大白鼠,体重200~350g,雌雄不拘,玻璃微电极细胞外记录NRM的单位放电。以串脉冲刺激鼠尾尖1/3处为伤害性刺激观察NRM神经元的自发放电及伤害性刺激后的反应。SM区损毁采用机械切除损毁法;电针双侧“足三里”,连续刺激5分钟。实验分三组进行,结果如下: 一、SM区损毁前记录了31个单位电针后0~25分,有激活神经元自发放电增加的倾向,经统计学处理差异不显著,而伤害性反应于针后0~30分受到明显抑制(P<0.01)。二、双侧顶叶SM后肢区损毁后4小时作电针效应观察,记录了30个单位。SM区损毁后电针对NRM神经元的激活作用增强,自发放电增加于电计后0~15分有显著差异(P<0.05),但对电针抑制伤害性反应的作用无明显影响,电针仍有明显的抑制效应(P<0.01)。  
        
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    • 1989(Z1): 35-36.
      摘要:Experiments were performed on rats, Unit discharges of NRM were reco- rded extracellularly with glass microelectrods, and their nociceptive responseswere induced by train electro-stimulation of tail. The effects of EA of bila-teral "Zusanli" points for 5 minutes were recorded, and the EA effects beforeand after lesion of SM cortices were compared. Results were as follows: 1. Before lesion of SM, the effects of EA on 31 noxious excitatory nocice-ptive units in NRM(including 2 raphe-spinal neurons) were recorded. EA hada tendency to activate the neurons and increase firing rate in 0-25 minutes,but obviously inhibited nociceptive responses of the neurons (P<0.01) in 0-30minutes.  
        
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    • 电刺激中缝大核对丘脑束旁核痛敏单位放电的影响

      李军, 李鸿勋
      1989(Z1)
      摘要:本实验在51只清醒麻痹大白鼠身上记录丘脑束旁核(Pf)痛兴奋单位(PEU)和痛抑制单位(PIU)的活动及其对刺激中缝大核(NRM)的反应,实验结果为:(1)无论脊髓背外侧索(DLF)被损毁与否,刺激NRM均可明显削弱PEU和PIU的伤害性反应;(2)刺激已被损毁的NRM无上述效应;(3)损毁9只动物的DLF和中脑中央灰质(CG)头端背侧部后,刺激NRM仍可削弱3个PEU的伤害性反应,而对4个PEU、2个PIU的伤害性反应不再起削弱作用。实验结果提示:NRM可通过脊髓以上的机制削弱Pf单位对痛传入的反应;对部分Pf单位而言,NRM完成这种效应有赖于CG头端结构的完整。  
        
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    • 1989(Z1)
      摘要:The effects of the nucleus raphe magnus (NRM) stimulation on the discha-rges of pain-sensitive units in the parafascicular nucleus (Pf) of 51 consciousand flaxedil-immobilized rats were examined. The main results were as follo-ws: (1) The nociceptive discharges evoked by peripheral noxious stimuli inpain-excitatory units of Pf (pfPEU) and paininhibitory nuits of Pf (pfPIU)were profoundly attenuated by stimulation of NRM before and after bilaterallesions of the dorsolateral funiculus (DLF) of the spinal cord; (2) Stimula-tion of the lesioned NRM had no effect on the nociceptive discharges of thepain-sensitive unite in the pf; (3) Lesions in the DLF and the rostrodorsal  
        
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    • 张守信, 刘乡, 魏北华
      1989(Z1): 37-38.
      摘要:本实验选择了对牙痛有特效的手阳明大肠经的上肢穴位“合谷”观察其对NRM神经元由牙髓和尾尖不同部位伤害性刺激所引起的镇痛作用是否相同,以分析穴位在电针镇痛中的特异性。实验用雄性大鼠,氨基甲酸乙酯麻醉,尾尖1/3处及下门齿牙髓各置一对刺激电极,用玻璃微电极细胞外记录NRM神经元的放电及分别由尾尖和牙髓刺激所引起的伤害性反应。共记录I4个NRM神经元,结果如下:  
        
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    • 1989(Z1): 38-39.
      摘要:The purpose of the study was to observe the effects of EA of 'Hegu' po-int, which was chosen for its specific effects on toothache, on the nociceptiveresponses of NRM neurons induced by stimulation of dental pulp or tail tip,to analyse the specificity of point for EA analgesia. The experiments were performed on male rats anesthetized with urethane.Unit discharges of NRM neurons were recorded extracellularly with a glassmicroelectrode and their nociceptive responses induced by stimulation throughelectrode inserted into dental pulp of inferior incisor teeth er in one thirdof tail tip respectively.  
        
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    • 范天生, 楚宪襄, 张学国, 孔天翰, 方智慧
      1989(Z1)
      摘要:脑干中缝大核是针刺镇痛的重要中枢部位之一。我们过去的工作已证明了其传入纤维的起源,为了继续探讨其传入纤维的递质性质,本实验用大白鼠17只,将微量的WGA-HRP注入中缝大核内,存活24—48小时,向侧脑室注入秋水仙素,24小时后灌注固定,冰冻切片,TMB成色,再经DAB-CoCl_2稳定,然后用PAP法分别显示5-HT神经元、P物质神经元,M-ENK神经元,L-ENK神经元,β-EP神经元及SRIF神经元。根据HRP和上述六种递质神经元的双重标记细胞在脑干内的分布,确定它们向中缝大核的递质纤维投射。结果如下:  
        
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    • 1989(Z1)
      摘要:Nucleus Raphe Magnus (NRM) is one of importent position in Acupunctureanalgesia. During the past few years the sites of origin of afferent fibersprojection to NRM were studied. In order to demonstrat some neurotransmittersin fibers projection to NRM, we utilized the combination of HRP with immuno-histochemical technique. Experiments were performed on 17 adult rats. HRPwere injected into NRM. After 24h, the animals were treated with colchicineinjected intraventricularly. The animals were perfused 24h following the co-chicine inj tion. Sections were cut on a freezing microtome add processedwith TMB-DAB-CoCl_2 method, then 5-HT, SP, M-ENK, L-ENK, β-EP andSRIF-labeled cells were demostrated with PAP method.  
        
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    • 脊髓和中缝大核区间的纤维联系

      楚宪襄, 范天生, 张学国, 孔天翰, 方智慧
      1989(Z1)
      摘要:实验用大白鼠17只,将微量WGA-HRP经微玻管直视下注入到中缝大核内,动物存活48—72小时后按HRP法经主动脉灌注取材。将脊髓分段(上颈、颈膨大、上胸、中胸、腰膨大、骶)。冰冻切片(20~40μm),TMB成色,明暗视野观察标记纤维的走行、终止和标记细胞出现的部位,确定脊髓和中缝大核区间的纤维联系。标记纤维密集排列于脊髓白质外侧索背侧部,位置表浅、范围由颈髓至骶髓逐渐减小。其终末广布于各段脊髓灰质Ⅲ、Ⅳ、Ⅴ、Ⅶ、Ⅷ、Ⅸ、Ⅹ层,以Ⅶ、Ⅷ层内最为密集。可见一些纤维呈串珠状自Ⅷ层内伸向前角细胞,形似溃变纤维之终扣。有些标记纤维自外侧索发  
        
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    • 1989(Z1): 41-42.
      摘要:Experiment were performed on 17 adult rats. WGA-HRP was injected inNucleus Raphe Magnus (NRM) with micropiped under view. The animals wereallowed to survive for 48-72h, and then fo perfuse the fixative passing theaortac. Spinal cord was blocked in seven segments: upper cervical, cervicalenlargement, upper thoracic, medial thoracic, lower thoracic, lumbar enlarge-  
        
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    • 中缝背核及电针对大鼠脊髓背角神经元伤害性反应的影响

      俞光弟, 郭试瑜, 张惠琴, 印其章
      1989(Z1): 42-43.
      摘要:本实验用电生理方法记录刺激中缝背核(DR)影响清醒制动大鼠脊髓背角伤害性单位放电。并探讨DR在痛觉调制及电针镇痛过程中的下行性抑制作用。在脊髓L_3的背角区上,记录到的结果如下: 1.当刺激坐骨神经时背角伤害性单位放电频率随刺激强度的增大而升高。在55个单位中,痛敏型细胞为24个,广动力范围型细胞为31个。  
        
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    • 1989(Z1): 43-44.
      摘要:In order to further analyse the role of descending inhibitory pathway fromdorsal rophe nucleus (DR) in pain modulation and acupuncture, the unit dis-charge of spinal dorsal horn neurons was recorded at L_3 level in immobilizedrats and the responses of dorsal horn neurons to nociceptive stimulus as wellas the influence of DR stimulation were observed with electrophysiologicalmethods combined with pharmacological analyses. The results were as follows: 1. The nociceptive unit discharge rate was increased as stimulation inten-sity of sciatic nerve. Among the 55 units, 24 were pain specific units and31 units which were wide dynamic range neurons.  
        
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    • 海马结构在痛觉调制和针刺镇痛中的反应的研究

      刘祚周, 廖维宏
      1989(Z1)
      摘要:我们研究了海马在痛觉调制或镇痛机制方面的作用。当给以伤害性刺激时动物血压的上升与海马脑电高振幅长时程的慢波节律性活动(SRA或θ节律)相伴随,具有一定的特异性,可以作为伤害性反应的指标之一。实验表明,外周躯体伤害性刺激往往引起血压升高,而牵拉内脏的外周刺激多出现血压下降,两者反应不同。向侧脑室内注入阿托品可以翻转伤害性刺激时海马SRA和血压的变化。注入毒扁豆硷则无此作用。故可以考虑,伤害性刺激时海马SRA反应和相伴随的血压变化可能与中枢胆硷能M受体的激活有关。  
        
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    • 1989(Z1): 45-46.
      摘要:It has been proved that the hippocampal formation is closely related tosome behaviour reactions (such as learning and memory), visceraI activities,and neuro-endocrine regulations. However, what roles the hippocampus mayplay in pain modulation and analgesic mechanism still need further studies.So we have done some works in this field. The blood pressure increased accompanying hippocampal EEG's slowrhythmic activity (SRA or theta rhythm) which had a higher amplitude and alonger time course. This EEG wave was specific and could be used as one ofindexes of nociceptive response. Our experiments also demonstrated that theblood pressure increase could be induced by peripheral somatic noxious stimu-  
        
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    • 廖维宏, 冯正直, 毕晓宁, 刘祚周
      1989(Z1): 46-47.
      摘要:本研究目的是观察离子微电泳5-HT及其拮抗剂二甲麦角新碱对海马伤害性感受单位的作用。实验用大鼠,在氯醛糖和乌拉坦麻醉下手术,用箭毒制动,以强串电脉冲刺激隐神经,用6管玻璃微电极和立体定向技术作细胞外记录和离子微电泳。结果如下: 1)伤害性兴奋单位(n=84)离子微电泳5-HT过程中(n=38)放电减少的24个;电  
        
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    • 1989(Z1): 47-48.
      摘要:In this study an attempt was made to observe the effects of iontophoreticapplication of 5-HT and methysergide on the nociceptive units. CA1 area ofhippocampus (HPC). Experiments were performed on 50 rats anaesthetizedwith choralose and urethane. The animals were immobilized with d-tubocura-rine. Stimulation of the sephenous nerve with a train of electric pulses wasused as a noxious stimulus. Single units were recorded extracellularly by the6-barrelled micropipett with stereotaxic techenique.  
        
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    • 电针对侧脑室注射马桑内酯所致海马单位痫样放电的观察

      高唱, 廖维宏, 杨继曾
      1989(Z1): 48-49.
      摘要:本文目的在于提供新的实验性癫痫模型,从细胞水平上观察电针对海马单位痫样放电的影响。雄性大鼠,内侧脑室注射马桑内脂30微克。同步记录注射侧海马单位放电和皮层电图。电针大椎、身柱、太冲、昆仑穴。 (1)注射后1~10分针皮层电图出现散在棘波,随后棘波频率逐渐增高,幅度增大,约在注射后40~90分钟达顶峰,顶峰期可持续60~90分钟,痫波可维持3—5小时。  
        
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    • 1989(Z1): 49-50.
      摘要:In our present study we build up a new experimental model in the rat forepilepsy and examine the effects of electroacupuncture on epileptiform hippo-campal unit activity. Experiments were carried out on conscious immobilized male rats, CoriariaLactone at a concentration of 30μg/10μl in saline was injected intracerebrove-ntricularly. Electrocorticography (ECoG) and hippocampal unit activity wererecorded simultaneously on the side of brain which received the drug injection.In some cases, the hippocampal EEG was also recorded. Acupuncture of Da-zhui, Shenzhu, Taichong and Kunlun were stumulated respectively.  
        
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    • 尾核内阿片肽及某些经典递质参与针刺镇痛

      何莲芳, 许绍芬, 陆文孝, 陆瑞良, 周光钊
      1989(Z1): 50-51.
      摘要:尾核内富于某些经典递质及阿片受体,近年来对它们在针刺镇痛中的作用积累了研究资料。在慢性实验兔中观察到电针可以增高痛阈并同时增加尾核内阿片样物质的释放;针刺镇痛作用可被尾核内微量注射钠洛酮所阻断。急性实验中观察到电针可以对尾核神经元产生很强的抑制作用,与微电泳羟戊甲吗啡的作用相似,该作用亦可被微电泳钠洛酮所阻断。免疫组  
        
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    • 1989(Z1): 51-52.
      摘要:The caudate nucleus is rich in some opioid peptides and classical transmit-ters the role of which has been studied for recent several years. In chronicrabbits, it was found that electroacupuncture (EA) could increase pain thres-hold and the release of opiate like substance from the caudate; the effect ofEA was readily reversed by naloxone microinjected into the caudate. Acuteexperiments revealed that EA, like microiontophoretic etorphine, producedstrong, naloxone reversible inhibition on some caudate neurons. Immunohisto-chemical study showed leu-enkephalin like immunoreactivity in the perikaryaand neuronal process of the rat caudate. The result was in accordance with  
        
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    • 刺激尾核对大鼠束旁核伤害性神经元的抑制作用

      严泓渠, 何莲芳
      1989(Z1)
      摘要:近年来研究证实尾核参与针刺镇痛,其作用系部分通过内阿片肽而实现。本工作观察刺激尾核对束旁核神经元伤害性反应的抑制及内阿片肽在其中的可能作用。用多管微电极离子微电泳技术记录及测试束旁核神经元活动。在所观察的289个单位中有32个对伤害性刺激(铗皮及强电震刺激尾部)有兴奋性反应,8个有抑制性反应。在伤害性兴奋型单位中,微电泳羟戊甲吗啡对自发放电影响不大,而对诱发反应有明显的抑制作用。一般在微电泳后3分钟抑制作用最强,约在15分钟后恢复。尾核刺激对伤害性兴奋型  
        
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    • 1989(Z1): 52-53.
      摘要:Recent studies have provided substantial evidence indicating the participa-tion of the caudate nucleus in acupuncture analgesia partly via endogenousopioid peptides, The present work investigated caudate stimulation produced inhibition on neciceptive response of the parafascicular nucleus and the possibleinvolvement of opioid peptides in the inhibition.  
        
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    • 胡中庭, 黄登凯, 何莲芳, 李宽孍, 王庆平
      1989(Z1): 53-54.
      摘要:本实验应用[3H]—2脱氧葡萄糖定量放射自显影技术研究了电刺激尾核头部前区镇痛时对中枢神经系统有关结构葡萄糖代谢率的影响。实验动物共分四组;对照组,痛刺激组,电刺激尾核组,尾核刺激加痛刺激组(刺激尾核镇痛组)。本实验共测定由脊髓至端脑共40个神经结构并将各组相关结构的葡萄糖代谢率进行了组内,组间t检验。本文还对刺激尾核镇痛的主要环节进行了讨论。  
        
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    • 1989(Z1): 54-55.
      摘要:Sokoloff's 2-deoxyglucose (2-DG) autoradiographic technique was used toidentify neural structures underlying analgesia pioduced by stimulating head ofcaudate nucleus. Sixteen adult albino rats were divided into four groups: 1)noxious stimulation, 2) noxious+unilateral caudate stimulation, 3) unilateralcaudate stimulation, 4) control.  
        
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    • 大鼠尾-壳核内一种特殊类型的痛反应神经元

      马和平, 李柏岩, 徐屯
      1989(Z1)
      摘要:采用常规的鉴定方法,在43只雄性Wistar大鼠的尾-壳核内共筛选了80个痛反应神经元,其中痛兴奋神经元为58个,痛抑制神经元为22个。实验发现,同是痛兴奋神经元其自发放电的频率差别较大,痛诱发放电的潜伏期相差也较为悬殊,最短的为100ms,最长的可达3200ms。  
        
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    • 1989(Z1): 55-56.
      摘要:By the method of repeated noxious stimuli to sciatic nerve we studied theelectrical activities of pain excitation neurons, that is, during the dischargesevoked by the former noxious stimulation (S_1) the latter noxious stimulation(S_2) was given in order to observe the responses to S_2. Two types of respon-ses to S_2 were found in the caudate-putamen nucleus (CPU): (1) S_2 incre-  
        
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    • 马玉羡, 谷瑞民, 孙明智
      1989(Z1)
      摘要:本工作采用细胞外记录神经元电活动的方法,对尾核和多巴胺与痛觉的关系作进一步的探讨。实验用Wistar大鼠38只,用玻璃微电极引导尾核神经元放电。以痛兴奋神经元(PEN)的痛诱发放电频率秒净增值,痛抑制神经元(PIN)的痛抑制时程为指标,观察了脑室注射多巴胺(DA)70μg/10μl对两种痛反应神经元电活动的影响。在双侧尾核共观察记录了129个痛反应神经元的电活动,其中PEN 70个,占54%;PIN59个,占46%。成对记录的为33对,PEN-PEN12对,PIN-PIN11对,PEN-PIN10对。  
        
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    • 1989(Z1)
      摘要:In this experiment, the relationships between Dopamine (DA) and painsensation were studied with the method of the neuronic dischargs induced bythe glass microelectrode in caudate nucleus of 38 rats. The resultes of thepresent experiment showed that the electric activity of PEN could selectivelybe excited by intraventricular injection of DA, while that of PIN inhibited.The same phenomenon was found in the neurons which were recorded inpairs in N. Cd., and the activities of PEN and PIN were well cooperated. Theeffects of DA could be blocked by intra-abdominal injection of droperidol.  
        
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    • 马玉羡, 谷瑞民, 孙明智
      1989(Z1): 57-58.
      摘要:本实验采用玻璃微电极细胞外记录尾核神经元放电的方法,以尾核痛兴奋神经元(PEN)和痛抑制神经元(PIN)的电活动变化为痛反应指标,观察尾核内注射DA及刺激黑质致密部对PEN和PIN电活动的影响,探讨黑质-纹体DA能系统在痛觉调制过程中的作用。实验用体重250~320克大鼠47只,在清醒麻痹、人工呼吸条件下进行实验。  
        
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    • 1989(Z1)
      摘要:The present experiment aims to verify the influence of intracaudate midro-injections of dopamine (DA) and electric stimulation of the pars compacta ofsubstantia nigra (SNC) on the evoked discharges in pain-excitation neurons(PEN) and pain-inhibition neurons (PIN) in the ipsilateral caudate nucli ofthe rat. The result showed that DA injection and SNC stimulation couldincrease the frequency of the evoked discharges in PEN and lengthen the dur-  
        
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    • 高美兰, 张均明, 刘荫仁
      1989(Z1)
      摘要:尾核是脑内重要的镇痛结构之一,它对中脑网状结构(MRF)痛敏神经元的放电是否有调制作用?为此,我们观察了伤害性刺激、电针穴位以及刺激尾核头部对MRF痛敏神经元放电的影响。本实验用38只家兔,在MRF中记录了496个自发放电的神经元其中对伤害性刺激有反应的神经元共116个。这些神经元基本分两类,即痛兴奋神经元64个,痛抑制神经元52个。痛兴奋神经元对电刺激腓神经表现为高频放电,反复刺激无适应,电针“合谷”穴位放电频率减少或者短暂消失。痛抑制神经元对电刺激腓神经表现为放电频率减少,反复刺激同样无适应,电针“合谷”穴位放电频率增加(脱抑制)。  
        
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    • 1989(Z1): 59-60.
      摘要:38 rabbits were used in this Experiment 116 of the nociceptive units responded to noxious stimuli which were applied to the peroneal ne ve with ashort train of pulses. Among them, 64 units (60%) responded by an increasein frequency of the discharge to noxious stimuli (pain-excition neuron, PEN).In contrast, there were 52 units (40%), which responded to noxious stimuliquite differently, by having a decrease in the frequency of the discharge (pain-inhibition neuron, PIN). Similar results were obtained by the stimulation of  
        
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    • 视前区儿茶酚胺神经末梢和阿片受体的关系

      朱津民, 何晓平, 李宽孍, 黄登凯, 曹小定
      1989(Z1)
      摘要:视前区富含内阿片肽、阿片受体和儿茶酚胺(CA),该区的CA主去要为去甲肾上腺素(NA)。我们曾经观察到针刺镇痛时视前区的内阿片肽对NA的释放有抑制性作用。但是其作用机理尚不明瞭。本实验以CA选择性化学性切割剂6-羟基多巴胺(6-OH DA)损毁家兔双侧蓝斑下核(A_7核团)的NA神经元以及上行CA腹侧束后,用甲醛诱发荧光组化法和阿片受体结合的放射自显影法,观察其对视前区CA末梢荧光组化和阿片受体分布和密度的影响,探讨视前区CA末梢和阿片受体的关系。  
        
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    • 1989(Z1)
      摘要:It has been reported that in the preoptic area endogenous opioid peptidescould inhibit the noradrenaline release in vivo and in vitro. In the presentstudy, receptor autoradiography on the rabbits' brain slices was used to inve-stigate the distribution of 3H-etorphine binding sites before and after thedestruction of noradrenaline neurons in n. subcoerulcns and ascending catecho-lamine (CA) axons by 6-hydroxydopamine. The results provide us with mor-phological evidence that 3H-etorphine binding sites before and after thedestruction of noradrenaline neurons in n. subcoerulcns and ascending catecho-lamine (CA) axons by 6-hydroxydopamine. The results provide us with mor-phological evidence that 3H-etorphine binding sites in the preoptic area,  
        
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    • 针刺镇痛时视前区β-内啡肽和去甲肾上腺素释放的变化

      朱津民, 何晓平, 曹小定
      1989(Z1): 61-62.
      摘要:已有文献报道视前区内阿片肽活动有加强针刺镇痛作用。我们以前的工作表明视前区NA的活动不利于针刺镇痛。本实验取同时收集的家兔视前区灌流液,分别采用放射免疫法和高效液相色谱法测定其中β-内啡肽样免疫活性物质(β-EPIS)和NA及其代谢产物MHPG含量的变化,并分析在针刺镇痛过程中的两者的关系。  
        
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    • 1989(Z1)
      摘要:Push-pull perfusion technique was used to collect the perfusate from therabbit's preoptic area before and after 10 rain of acupuncture, β-endorphinlike immunoreactive substances(β-EPIS) and noradrenaline as well as 3-methoxy-4-hydroxyphenylglycol (MHPG), a noradrenaline metaboliste, of the perfusatewere detected by RIA and HPLC-ECD. It was found that acupuncture could  
        
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    • 视前区去甲肾上腺素和多巴胺在针刺镇痛中的作用

      朱津民, 曹小定
      1989(Z1)
      摘要:我们以前曾观察到,视前区注入6-OH-DA选择性损毁儿茶酚胺神经末梢可以加强针刺镇痛作用,提示视前区儿茶酚胺可能参与针刺镇痛作用。本实验采用高效液相色谱法测定针刺镇痛时视前区活流液中去甲肾上腺素(NA)、多巴胺(DA)和代谢产物含量的变化,并分析NA参与针刺镇痛的可能受体机制。一、针刺镇痛时视前区灌流液中NA、MHPG和DA含量的变化。针刺10分钟后,家兔痛阈明显升高,此时视前区灌流液中的NA和MHPG含量明显减少,DA的含量虽有上升趋势但统计学处理无显著变化。二、视前区注入NA和DA对针刺镇痛的影响。  
        
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    • 1989(Z1): 63-64.
      摘要:Previous work has shown that activation of catccholamine in the preopticarea is to the disadvantage of acupuncture analgesia. In this work microinje- otion and pushpull perfusion as well as HPLC-ECD were used to observe theeffect of noradrenaline and dopamine in this area on acupuncture analgesia,The results indicated that microinjection of noradrcnaline (0. 5μg/unilateral)into the preoptic area could attenuate acupuncture analgesia, while dopamine  
        
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    • 朱津民, 李宽孍, 曹小定
      1989(Z1)
      摘要:视前区是脑内与针刺镇痛有关的结构之一。视前区含有丰富的儿茶酚胺(CA)神经末梢。本实验用6-羟基多巴胺(6-OH-DA)的化学性损毁术和甲醛诱发荧光组化法观察家兔视前区注入6-OH-DA(8μg/双侧)选择性损毁该区CA神经末梢后,对针刺镇痛的影响。荧光组化法显示注药后视前区CA末梢明显减少,而注射配药液的动物视前区CA末梢未见明显变化。  
        
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    • 1989(Z1)
      摘要:The effect of microinjection of 6-hydroxydopamine into the preoptiearea was studied to observe the effect of catecholamine depletion in the preo-ptic area on acupuncture analgesia. It was shown that the analgsie effect ofacupuncture was significantly enhanced in the 6-hydroxydopamine group onthe second and fourth day after injection as compared with those before inje-  
        
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    • 下丘脑内侧视前区在电针影响蓝斑核神经元放电中的作用

      朱笛霓, 赵建础
      1989(Z1): 65-66.
      摘要:本实验以蓝斑(LC)神经元放电为指标,观察刺激内侧视前区(MPO)对LC神经元放电的影响,及与电针的关系。结果如下: 1.在42个LC神经元中,29个(69.0%)被电针激活,5个(11.9%)被电针抑制,8个无反应。 2.在42个LC神经元中,16个(38.1%)神经元被刺激MPO激活,它们主要分布于背侧LC及蓝班下核,22个神经元被刺激MPO所抑制(52.4%),它们主要位于路侧LC,4个神经不产生反应。  
        
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    • 1989(Z1): 66-67.
      摘要:The purpose of this paper is to study the effect of stimulation of medialpreoptic area (MPO) on the discharge of coeruleus (LC) cells and its relationwith EA. The main results are as follows: 1. In 42 LC neurons analysed, 29 (69. 0%) were excited by EA, 5(11. 9%)inhibited and 8(19. 1%) unaffected. 2. Of these, 16(38. 1%) were excited by stimulation of MPO, locateddorsal LC and subcoeruleus; 22 (52. 4%) inhibited located ventral LC mainly, 4unaffected.  
        
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    • 印其章
      1989(Z1)
      摘要:已知下丘脑弓状核(ARC)的β-内啡肽能(β-END)系统中缝背核(DR)的5-羟色胺能(5-HT)系统和蓝斑(LC)的去甲肾上腺素能(NE)系统在各种镇痛中起着重要作用。形态学资料也表明,在这三个核团之间存在着相互的神经支配。本研究室近10年来,以大鼠为实验动物,主要应用行为测痛的方法和电生理学技术,结合采用神经生化、荧光组化、免疫组化和神经药理学等手段,着重研究这三个核团在针刺“人中”、“承浆”、或“足三里”、“三阴交”镇痛中的作用以及它们之间的相互关系。实验结果发现,电刺激ARC、DR和LC这三个核团均能使针刺镇痛效应增强;相反,电解损毁和化学损毁这三个核团均能使针刺镇痛效应减弱。针刺均能激活这三个核团中的大多数神经元,并能抑制其伤害性反应。  
        
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    • 1989(Z1): 68-69.
      摘要:It has been demonstrated that the following three neuronal systems playan important role in different kinds of analgesia, i. e., β-endorphinergic(B-END) system in hypothalamic arcuate nucleus (ARC), serotonergic (5-HT)system in dorsal raphe nucleus (DR) and noradrenergic(NE) system in locuseoeruleus (LC). Morphological studies have revealed that there are reciprocalnervous innervations among these three nuclei. In the last decade, the role and theinterrelationship of ARC, DR and LC in acupuncture analgesia (AA) (Acu-points: "Renzhong" and "Chenjiang" or "Zusanli" and "Sanyinjiao") werestudied on rats in our laboratory, mainly with behavioral pain test andelectrophysiological technique combined with neurochemieal, fluorescent histo-chemical, immunocytochemieal and neurophrmaeological methods.  
        
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    • 于龙川, 韩济生
      1989(Z1)
      摘要:本室以往的工作表明,从中脑导水管周围灰质(PAG)有一条上行镇痛神经通路到达伏核,在伏核内5-羟色胺和甲啡肽参与镇痛信息的传递。本工作在家兔脑内埋植慢性套管,采用脑内微量注射抗体的方法研究下丘脑弓状核(ARH)及β-内啡肽(β-EP)是否参与上述镇痛神经通路。研究结果如下: 1.在家兔PAG内微量注射吗啡10微克可产生明显的镇痛作用,该作用可被伏核内微量注射β-EPIgG1.10或20微克所削弱,并有量效关系。 2.损毁家兔的ARH一周以后,在伏核内注射β-EP IgG10微克则不能明显削弱PAG内注射吗啡所产生的镇痛作用。  
        
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    • 1989(Z1): 69-70.
      摘要:It was found that the analgesic effect of morphine administered to peri- aqueductal grcy(PAG) of the rabbit was significantly attenuated by β-EP IgGinjected into the nucleus accumbens. This antagonistic effect was totallyabolished by lesioning of the ARH. However, lesioning of ARH showed nosignificant influence on the analgesia produced by intra-PAG-administeredmorphine, nor did it abolish the reversal of morphine analgesia by naloxoneadministered to nucleus accumbens.  
        
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    • 不同频率电脉冲刺激大鼠下丘脑外侧区对痛阈的影响

      李淑捷, 孙文颖, 陈水村
      1989(Z1)
      摘要:本实验用热辐射器给鼠尾热伤害性刺激,以甩尾反应的潜伏期作为痛阈,观察不同频率的下丘脑外侧区(LHA)刺激对甩尾反应阀值的影响,借以探讨LHA刺激镇痛效应的适宜刺激频率,并观察腹腔注射赛庾啶对LHA镇痛效应的影响。用4、10、70Hz三种不同频率刺激LHA,停止刺激即刻大鼠痛阈分别提高35.1%、61.2%及58.3%,这种差别与三种频率作用的先后顺序无关,可见4Hz的镇痛效应最差。但就痛阈升高的持续时间比较,在停止刺激LHA5分钟时,痛阈提高百分率分别为15.1%、32%及14.4%,停止刺激10分钟时痛阈提高百分率分别为8.7%、21.1%及3.5%,可见以10Hz的后效应最长,以上提示中频10Hz频率的刺激是LHA核团刺激镇痛的适宜频率。  
        
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    • 1989(Z1)
      摘要:Pain threshold of rat was determined by the latent period of tail flickelicited by radient heat. On electrical stimulation of the lateral area ofhypothalamus(LHA) with 4 Hz, 10Hz and 70Hz stimuli, the pain thresholdraised 35. 1%, 61. 3% and 58. 3% respectively. The duration of raised painthreshold was longest after 10Hz stimuli (+32% and +21. 2%, 5 and 10 minafter ceassation of stimulation). The analgesic action of LHA stimulationwas deaereased markedly after ip cyproheptadine.  
        
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    • 潘建粹, 金国章
      1989(Z1)
      摘要:1,HVM微注NE(3μg/3μl)能产生强而持久的针刺镇痛效应,并以腹内侧核为最强,NE的增强效应主要通过α_1受体与β受体无关。2,HVM微注DA的协同作用不及NE强而持久,5-HT则无协同作用。表明具有递质的专一性。3,HVM微注NE增强电针镇痛作川与脑内阿片系统有关,其作用途径是通过AR阿片肽神经元和PAG腹侧部的阿片受体而发挥作用的,当MSG损毁AR的阿片神经元后,有关内源性阿片肽含量下降;这些脑区的阿片功能破坏,故在HVM微注NE的增强电针镇痛效应亦因此消失。  
        
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    • 1989(Z1)
      摘要:1. The microinjection of NE into the ventromedial area of hypothala-taus had a much stronger potentiatioa effect on AA which Tasted for 24hours. It was mediated by α-adrenoreceptor, this potentiating effedt is morespecific in the ventromedial area of hypothalamus than in other neighboringnuclsui, 2. When the DA was microinjected into the ventromedial area ofhypothalamus, the potentiating effect was slight and lasted shorter in compa-risn with the NE. The 5-HT in the hypothalamus was not possible to pariti-  
        
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    • 缰核与GABA、乙酰胆硷

      吴建群, 王绍
      1989(Z1): 72-73.
      摘要:缰核作为边缘前脑联接脑干的驿站,在痛觉的整合过程中起重要作用。针刺条件下缰核是在边缘前脑诸结构的强力抑制下降低它的活动水平,使痛阈升高产生针刺镇痛的效应。我室以往的工作证明,电刺激隔区能强力抑制缰核神经元的自发放电活动。隔区是缰核传入纤维的主要来源。什么是隔区对缰核的投射纤维的抑制性递质本实验作了一些初步的探索。用同心圆电极刺激隔区,用多管微电极记录对刺激隔区呈抑制性反应的神经元自发放电并对其微电泳GABA、Bicuculline、和ACh。GABA可完全抑制缰核神经元的白发放电,  
        
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    • 1989(Z1)
      摘要:The habenular nucleus is a relay in the descending pathway from the fore-brain limbic system to the brainstem. It's activity is inhibited by the influ-ences from the related structures of limbic forebrain which is activited byacupuncture. Then, the analgesic effect is produced. What is the neurotran-smitter mediated the relation between them, the experiment is carried out toanswer this question. The unit spontaneous firings from habenular nucleusare recorded with the central tube of multielectrode (3—5 Barrels). Duringthe interval of firing rate decreased by electrical stimulation of septal area,  
        
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    • 脚内核经缰核的镇痛作用

      张唯, 王绍
      1989(Z1): 73-74.
      摘要:本实验应用核团内微量注射L-谷氨酸、利多卡因、Bicuculline、GABA,用辐射热甩尾法测定大鼠痛阈以及记录单位放电的方法探讨了脚内核经缰核的痛觉调制作用。并讨论了这一作用的可能机制。双侧脚内核分别微量注射25nmol、50nmol、400nmol L-谷氨酸0.5μl兴奋脚内核,无论其浓度高低均引起动物病阈升高,注射剂量与痛阈升高之间有明显的剂量效应关系。缰核内注射2%利多卡因0.5μl可大部分阻断脚内核注射L-谷氨酸引起的动物痛阈升高作  
        
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    • 1989(Z1): 74-75.
      摘要:The aim of this experiment was to clarify if the entopeduncular nucleuscan modulate the pain threshold through habenular nucleus mediated the actionbetween nuclei entopeduncular and habenular. L-glutamic acid (excitatory acid thai can excite the neuron body ratherthan passed fibers), bicuculline (a GABA receptor antagonist), lidocaine andGABA were injected into entopeduncular and habenular nuclei respectivelythrough the implanted cannula. Pain threshold was measured by the latencyof avoidance response (tail-flick) elicited by radiant heat applied to the tailskin of animals before and after intracerebral injection. In some cases single-unit activity in the habenular nucleus was recorded when the entopeduncularnucleus was electrically stimulated.  
        
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    • 红核的镇痛作用和对电针镇痛的影响

      刘敏芝, 刘先国, 刘佰运
      1989(Z1)
      摘要:长期以来人们认为红核的主要机能是调节躯体运动和肌紧张,但近来有工作指出它与感觉调制有关。本工作的目的是探讨红核的镇痛作用及其与电针镇痛的关系。以大鼠甩尾反射作痛阈的指标,观察了红核对痛觉的调制作用,单独向大鼠双侧红核注射中枢兴奋剂L—谷氨酸(0.2M;每侧0.5μl,2分钟注完)可使甩尾反射痛阈明显升高,单独用利多卡因阻断中缝大核(NRM)对痛阈无明显影响。若用利多卡因阻断NRM,同时向红核注入与前同量的L—谷氨酸,则升高痛阈的作用明显减弱。说明红核兴奋时有镇痛作用,在其对痛觉的下行抑制通路中NRM起重要作用。  
        
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    • 1989(Z1): 76-77.
      摘要:In general, it is believed that the red nucleus (RN) was related in controlof somatic movement and muscle tonus. Recently there have been few reportson its modulation of sensory function. The present study manifests the ana-lgesic effect of RN and the relationship between RN and acupuncture analgesia. The pain modulation function of RN was researched with tail flick reflexof rats as the standard of the pain threshold. The pain threshold of tailflick reflex was raised significantly by bilateral microinjection of L-glutamate  
        
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    • 陈正秋, 阎亚生, 王柯慧, 徐维, 施婷
      1989(Z1)
      摘要:本文借助于神经干复合动作电位、镇痛药氯胺酮、吗啡,以及辣椒素等,对不同强度电刺激腓浅神经引起的猫的中央中核(CM)神经元的反应进行了分析,并观察了电针效应。 1.对65例神经元(增频反应55例,减频反应10例)通过动作电位观察了不同刺激强度的效应。 65例神经元可分为两大类:一类是对Aδ纤维的兴奋即起反应的低阈值神经元(增频反应32例,减频反应3例);另一类是仅对C纤维兴奋才起反应的高阈值神经元(增频反应23例,减频反应7例)。  
        
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    • 1989(Z1): 78-79.
      摘要:Neuronal responses in the nucleus centrum medianum (CM) to electricalstimulation of the contralateral superficial peroneal nerve with various inten-sities were extracellularly recorded and analyzed by means of monitoringcompound action potentials, intravenous injection of ketarnine or morphine,topical application of capsaicin at the nerve proximal to the site stimulated toclarify what responses were actually nociceptive.  
        
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    • 大鼠丘脑束旁核痛抑制—兴奋神经元及其电活动的特征

      李柏岩, 马和平, 徐屯
      1989(Z1)
      摘要:在丘脑束旁核发生增频反应神经元诱发放电的基础上再次或反复刺激的方法发现,部分神经元表现为先抑制后兴奋,所以我们将这类神经元称为痛抑制一兴奋神经元(PI-EN)。本实验共观察了39个PI-EN,主要目的是为了证实PI-EN的存在,并观察其电活动的特征。束旁核PI-EN对单个刺激表现为增频反应,反应出现前有942.00±304.50ms(n=24)的无放电期,在PI-EN诱发放电的基础上再次或反复刺激时,其诱发放电被中断,出现短暂的抑制相(抑制性反应)持续时间恒定,抑制性反应后再次放电的频率增加,持续时间延长。我们认为在单个刺激出现增频反应之前也有抑制性反应存在。  
        
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    • 1989(Z1): 79-80.
      摘要:The present studies indicated.that the pain-discharges of some of neuronsshowed responses of increasing frequency were stopped temporarily for a period of time by noxious stimulation administrated again and repeatedly basedon the pain-discharges, and then the discharges appeared onee more. Thesepart of neurons were named pain inhibition-excitation neurons (PI-EN). Thepurporse of this experiment was to prove the existenee of PI-EN in Pf andobserved the charaeteristies of eleetriel activities of PI-EN, 42 PI-EN in Pfwere recorded.  
        
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    • 李玉荣, 杨玉芝, 孙明智
      1989(Z1): 80-81.
      摘要:实验用Wistar大鼠36只。在清醒、麻痹、人工呼吸条件下,以玻璃微电极引导丘脑束旁核痛兴奋神经元(PEN)和痛抑制神经元(PIN)的放电,观察脑室注射GABA对PEN诱发放电频率、潜伏期和PIN诱发抑制时程的影响,探讨外源性GABA对痛觉的调制作用。结果如下: 一、脑室注射GABA 1毫克可明显地抑制PEN的诱发放电(18/24)。使PEN放电的潜  
        
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    • 1989(Z1)
      摘要:The influence of intraventricular injection of GABA on electrical activi-ties of PEN ann PIN in nucleus parafascicularis of the thalamus of rats wasstudied. The results showed that GABA could significantly inhibit the elect-rical discharges of PEN and increase the electrical discharges of PIN. So itwas believed that intraventricularly injected GAGA could antagonize or partlyantagonize the excitatory action of noxious stimuli and might thus produceanalgesia.  
        
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    • 孙明智, 范平, 张季叶, 徐伯阳, 徐屯
      1989(Z1): 81-82.
      摘要:本工作用玻璃微电极细胞记录丘脑束旁核痛敏神经元电活动的方法,观察了脑室注射乙酰胆碱对丘脑束旁核痛兴奋和痛抑制神经元电活动的影响及阿托品对乙酰胆碱作用的阻断效应,并将乙酰胆碱的作用与吗啡对痛敏神经元电活动的影响进行了比较。 1.脑室注射乙酰胆碱能显著地抑制病兴奋神经元的诱发痛放电,使痛放电的潜伏期延长,持续时程缩短,频率下降。 2.脑室注射乙酰胆碱能部分或全部解除痛抑制神经元对伤害性刺激的反应,使完全抑制时程明显缩短。个别痛抑制神经元,脑室注射乙酰胆碱后,完全抑制时程延长。 3.在成对记录的痛敏神经元,脑室注射乙酰胆碱后,两个痛敏神经元的电活动同时发生变化,两个痛兴奋神经元的痛放电同时被抑制,两个痛抑制神经元的诱发痛抑制性反应同时被解除或一个痛兴奋神经元的痛放电被抑制,另一个痛抑制神经元的诱发抑制性反应被解除。  
        
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    • 1989(Z1): 82-83.
      摘要:The effects of intravcntricularly injected acetylcholine (ACh) on the ele-ctric activities of the pain-excitation neurons (PEN) and pain-inhibitionneurons (PIN) in nucleus parafascicularis (Pf) of thalamus were observed in67 rats. The effects of ACh were compared with that of morphine. The  
        
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    • 杨玉芝, 李玉荣, 孙明智
      1989(Z1)
      摘要:实验用Wistar大鼠42只,观察脊髓蛛网膜下腔注射GABA250μg/10μl或脑室注射GABA200μg/20μl对丘脑束旁核痛兴奋神经元(PEN)和痛抑制神经元(PIN)电活动的影响,探讨中枢不同部位外源性GABA对痛觉的调制作用。一、脊髓蛛网膜下腔注射GABA对大多数(38/44)PEN放电有明显的兴奋作用,表现为诱发放电频率增加、潜伏期缩短。诱发放电频率增加百分率以注射后4min最明显。与注射前和人工脑脊液对照组相比差异显著。二、脊髓蛛网膜下腔注射GABA可使48个PIN中36个的放电频率减少、抑制时程延长,注射后4min抑制时程延长明显。与注射前及人工脑脊液对照组相比差异非常显著(P<0.001)。  
        
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    • 1989(Z1)
      摘要:The electric activities of pain excitation neurons (PEN) and pain inhibi-tion neurons (PIN) in nucleus parafascicularis (N. Pf) of thalamus in 42 ratswere recored with microelectrodes by GABA intrathecally (i. th) injected andcompared with GABA intraventrieularly (i. c. v) injected. The results showed: that i. th injection of GABA (250/μg/5μl), the freque-ncy of the evoked discharges of PEN was increased and the latency shortened.The frequency of the evoked discharges of PIN was decreased and the inhibitoryduration prolonged. Whereas by i. c. v injection of GABA (200μg/20μ1), thefrequency of the evoked discharges of PEN was decreased and the latency  
        
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    • 佟振清, 陈水村
      1989(Z1): 84-85.
      摘要:本文主要观察刺激尾核Cd对丘脑束旁核躯体—内脏会聚(Pfsv)神经元放电的影响。实验用雄性大鼠27只,一同心圆刺激电极插入(Cd)在束旁核(Pf)用玻璃微电极引导单位放电。以引起C类纤维兴奋的短串脉冲刺激腓浅神经模拟躯体痛,刺激内脏大神经模拟内脏病。然后根据伤害性放电特点,在Pf探查对刺激腓浅神经和内脏大神经均出现伤害性放电反应的神经元,确定为Pfsy神经元。  
        
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    • 1989(Z1)
      摘要:The effects stimulation of caudate nucleus (Cd) of rats on nociceptivedischarges of somato-visceral converge neurons of the parafascicular nucleusof thalamus (PfSV) were studied, 1. When stimulation of Cd, the mean rate of nociceptive discharges of19 PfSV neurons was reduced by 7. 61+0. 85Hz(P<0. 01) and the duration offiring was shortened by 1. 38+0. 40sec. (P<0. 01) compared with that ofcontrol.  
        
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    • 中脑导水管周围灰质在电针镇痛和痛觉调制中的作用

      张长城, 李希成
      1989(Z1)
      摘要:我们对中脑导水管周围灰质(PAG)在针刺镇痛和痛觉调制中的作用进行了系列的研究,结果如下: 一、59只大鼠中发现给躯体和内脏大神经以伤害性刺激后,均可使80%的PAG单位放电发生增频反应。此外,躯体不同部位的伤害性信息和电针信息可使同一PAG单位发生增频反应,提示这种不同性质的信息可会聚到同一个PAG单位上,电针刺激“背俞,和“足三里”穴后,由电针刺激鼠尾或内脏大神经所引起的PAG伤害性单位放电活动,大多数均受到抑制。表明,PAG参与针刺镇痛的实现,它既可抑制躯体痛,又可抑制内脏痛。 PAG单侧和双侧损毁组的电针镇痛效应显著降低(P<0.01);而对照组的针效则无明显改变(P>0.05)。说明PAG在针刺镇痛过程中起重要作用。  
        
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    • 1989(Z1): 87-88.
      摘要:The role of PAG in the acupuncture analgesia 1. After noxious stimulation of splanchnic nerve or tail, the majority ofunits responded with increased frequency, some of units showed decreased fre-quency and the remainder had no response to both of noxious stimulation. Itseems to imply that PAG is one of the brain structures which receive somati-co-visceral pain impulses.  
        
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    • 延髓某些神经结构对脊髓神经元伤害性传递的下行调制

      杜焕基, 周诗逸
      1989(Z1): 88-89.
      摘要:脊髓伤害性信号的传递受来自延髓结构的下行调制。本研究比较了脊髓背角和第X层神经元的伤害性反应,分别观察了延髓中缝大核(NRM)和孤束核(NTS)对它们的抑制作用,并初步分析了NTS抑制效应的传出途径及其可能的神经递质。主要实验结果如下。 (1)许多第X层神经元(n=53)同背角深层神经元(n=37)一样,能被外周神经高强度刺激(≥30V)和感受野的伤害性机械或辐射热刺激以及腓肠肌动脉内注射缓激肽(20μg)所激活。静脉内注射Fentanyl(10μg)可以阻断上述伤害性反应。 (2)电刺激NRM对77.8(n=18)第X层神经元的伤害性反应产生象背角神经元一样的明显抑制效应。  
        
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    • 1989(Z1): 89-90.
      摘要:It is well known that the transmission of nociceptive signals at the spinalcord is modulated by the descending inputs from a number of medullary nuclei.In the present study, comparison of inhibitory actions of the nucleus raphemagnus (NRM) and the nucleus tractus solitarius (NTS) on the nociceptive ne-uronal responses in the spinal cord has been made, and the effective pathwayand possible neurotransmitters involved in the inhibitory effect produced byNTS stimulation has also been investigated.  
        
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    • 针刺镇痛的脊髓节段性抑制

      朱丽霞, 方宗仁, 黎春元, 于琴, 吉长福
      1989(Z1): 90-91.
      摘要:本工作系统研究了针刺与镇痛中脊髓节段性抑制机制。在脊鼠观察到电针次髎一环跳穴可提高甩尾阈(169.2±21.2%)、电针双环跳穴可抑制(背角神经元)腓肠神经刺激诱发的背角神经死伤害性反应(抑制了42.4±6.6%)、电针阳陵泉穴可抑制背角神经元踝关节刺激诱发的伤害性反应(抑制38.9±5.9%)以及电针内关、少海等穴可抑制脊猫(背角神经元)胸交感链刺激诱发的背角神经元伤害性反应(抑制62.9±5.10%及52.2±10.6%),镇痛效应均有显著意义,证明了针刺镇痛中脊髓节段性抑制的客观存在。  
        
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    • 1989(Z1): 91-92.
      摘要:A series of experiments were carried out on the spinal rats (including therats with the spinal cord hemi-transected dorsally) for investigating the spinalmechanism of acupuncture analgesia. The results are as follows: 1. In various spinal animals, needling certain acupoints may obtain signi-ficant analgesic effects. One or seven days after transection, the acupuncture-induced analgesic effect expressed with the tail flick latency was 39. 0% or62. 3% of that obtained in the intact rats. It suggests that the spinal segme-ntal inhibition migkt play an important role in AA.  
        
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    • 辣椒素对电针镇痛效应的影响

      方宗仁, 于琴, 李艳华
      1989(Z1): 92-93.
      摘要:针刺镇痛的研究中外周神经中那一类纤维参与针刺镇痛效应一直是个争论性问题。我们利用辣椒素镇痛效应一直是个争论性问题。我们利用辣椒素阻断外周神经中C纤维传入的效应来进一步分析这个问题。在大鼠用微电极记录脊髓背角细胞对电刺激腓肠神经所引起的放电。(3个脉冲串刺  
        
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    • 1989(Z1)
      摘要:It is argumentation that which fiber of periphral nerve is related to acu-puncture analgesia. The issue was studied by capsaicin to block the transmi-ssion of C-fiber of periphral nerve. The discharges of dorsal horn neurons to electrical stimulation of suralnerve were recorded by microelectrode in rats. The late discharges of dorsalhorn neurons was as a noxious response to strong stimulation (a train of 3 pu-lses, 25v intensity, 1ms duration.). Contralateral "Zusali" and "Sanyinjiao"points were stimulated electrically. The rats were anaesthetized with urethane(1. 2g/kg. i. p.) and immobilized with gellamine i. p.. The trachea was cannula-ted, artificial respiration was carried out.  
        
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    • 向脊髓下行性投射的细胞起源

      周敬修, 黄登凯, 李宽孍, 田启, 陆世铎, 笪翠娣, 卢毓青
      1989(Z1)
      摘要:针刺的上行性途径,通过新、旧脊丘索向上,研究得比较清楚,但下行抑制,到达脊髓是那些结构,对针刺发挥作用的机理来说至为重要。本研究以大鼠为材料,用戊巴比妥钠作腹腔内麻醉,在脊髓定向仪上进行颈、腰腹脊髓的辣根过氧化物酶溶液注射,存活1.5-2天后,连续切片进行四甲基联苯胺反应,提取脑和颈1—2段脊髓,观察其下行投射的细胞起源,部分切片还进行中性红复染,其结果如下: 1.颈、腰部脊髓HRP注射后可在束旁核,导水管周围灰质,脑干网状结构,中缝核、上丘深层、红核、三叉神经脊束核、脊髓背角和颈核等见到标记神经元,这些与疼痛及镇痛有关结构的下行投射,可能与疼痛及其调制有关。  
        
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    • 1989(Z1): 94-95.
      摘要:Anatomical and physiological studies on acupuncture analgesia indicatedthat the ascending pathway were passing through the new and old spinothala- mic route clearly, Yet what structures for the descenatng inhibition down tothe spinal cord are important for the mechanism of the acupuncture therapyneeds to be clarified. In the present work we studied the afferent fiber connections of the cervi-cal and lumbosacral segment of the spinal cord with horseradish peroxidase(HRP) injection in the rat. the results were as follows:  
        
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    • 夏勇, 潘卫星
      1989(Z1): 95-96.
      摘要:设正常对照、激光、电针三组。受试者平均年龄24岁,健康。采用同体对照。使用Neuropack-Ⅱ诱发电位仪记录痛刺激(每秒一次的电脉冲)右腕引起的对侧皮层体感区(C_3’)的正中神经体感诱发电位(SEP)激光照射或电针刺激施于左侧内关穴30分钟。结果除记录到同以往报导相同的N_(20)、P_(25)、N_(35)、P_(45)、N_(80)等成份外,还记录到N_(80)(潜伏时81.51±10.58ms)。有趣的是N_(80)在激光或电针中明显增高,均有非常显著的统计学意义(P<0.001)。10分钟和20分钟的记录已恢复,刺激前相比无显著差异(P>0.05);激光(电针)后10分钟与20分钟两次记录相比,无显著差异(P>0.1)。而对照组N80的变化无统计学意义(P>0.05)。  
        
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    • 1989(Z1): 96-97.
      摘要:This experimental study was carried out on 3 groups: normal subjeetLaser at point of left "Neiguan" and electro-acupunetue at point of left "Neiguan". SEPS were recorded in 85 healthy volunteers. The average age is 24 yearsold. The cases were compared with the same individual. SFPS were recorded by using evoked responses recorder "Neuropaek Ⅱ".SEPS evoked by stimulation of the median nerve at the right wrist and reco-rded it on left hemispheres. The acting of laser or electro-acupuncture wereapplied to point of left "Neiguan" about 30 minutes. The result of this expe-riment not ouly consisted of these different components of N20, P 25, N 35,P 45, N 60, but also consisted of this component of N 80 (mean latency 81. 51±  
        
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    • 针刺与交感神经对外周痛感受器的调制

      胡三觉, 陈敏, 朱军, 姜树军
      1989(Z1): 97-98.
      摘要:我们自1982年发现电针刺激“足三里”激活中把对外周痛感受器的传出抑制以来,采用单纤维分离记录技术,在感受器水平对这一传出作用的规律,途径与感受器类型进行了系统的研究,得到下述主要结果与结论: 1.刺激下丘脑外侧区可通过肾上腺—交感神经系统抑制外周伤害性传入冲动,刺激脑干中缝核等部位无此效应,表明下丘脑外侧区是交感神经传出抑制的中枢起源部位之一。 2.刺激坐骨神经中枢端可激活中枢对As—机械压痛感受器的传出抑制作用,切断交感神经几乎完全取消这一传出作用,证明其主要传出途径是交感神经。  
        
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    • 1989(Z1): 98-100.
      摘要:Since the centrifugal inhibitory effect of acupuncture on nociceptors wasfound in 1982, we have systematically studied the regularity of this action andits pathways using dissected technique of nerve fine bundles at nociceptor level.The main results and conclusions are as follons: 1. Electrical stimulation of the lateral hypothelamic area could inhibitthe peripheral noxious afferents through the adrenal gland-sympathetic system,indicating that the lateral hypothalamic area is one of the centres originatingthe centrifugal inhibitory effect on nociceptors.  
        
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    • 交感神经易化多觉型伤害性感受器的持续放电

      胡三觉, 朱军
      1989(Z1)
      摘要:采用神经纤维细束分离技术,分离大鼠尾神经的C类纤维,记录皮肤感受野注射复合致痛剂引起的多觉型伤害性感受器的持续放电(慢性痛放电)。刺激支配感受野的交感神经可使这种单位持续放电数量显著增多,部分单位为先易化后抑制。这种交感神经效应时程较长,可以反复激发。局部动脉注射去甲肾上腺素也引起类似效应,结果证实交感冲经能够易化多党型伤害性感受器的持续放电。提示处于持续放电状态的多觉型伤害性感受器对交感神经提出活动的敏感性,可能是交感神经触发与加剧烧灼痛的一个重要原因。进一步推论,采用适当的手法与参数,通过针刺减弱交感神经的传出活动,可能有助于缓解慢性持续痛。  
        
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    • 1989(Z1)
      摘要:Injection of a compound algogenic substance into receptive field of the skininduced sustaihed discharges of polymodal nociceptors in rats. The sustaineddischarges were obviously increased by stimulation of the sympathetic nerveinnervating the receptive field. Initial facilitation was followed by the inhibi-tion of discharges in partial units. The sympathetic effeet can be activatedrepeatedly and lasted for a prolonged time. Injection of noreprephrine (5μg/  
        
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    • 交感神经对多元型伤害性感受器的调制作用

      朱军, 胡三觉, 范谨之
      1989(Z1)
      摘要:本论文采用引导单纤维传入放电的电生理学方法和热烫甩尾测痛的行为实验模型,分别以鼠尾皮肤多党型伤害性感受器(PMN)传入放电和热烫甩尾潜伏期(TFL)为指标,在感受器水平对交感神经调制外周痛觉感受的作用过程进行了探讨。在电生理实验中、观察到刺激大鼠腰骶部交感5min,可使压力刺激诱发的PMA传入放电先增加后减少,腹腔注入外周交感神经阻断剂6—OHDA,上述交感神经刺激效应消失。结果表明,交感神经对诱发的皮肤PMN传入放电具有先易化后抑制作用。尾动脉注入去甲肾上腺素(NE)产生与交感神经刺激类似的效应;酚妥拉明可部分阻断这种效应。提示,交感神经对PMN的调制作用,可能  
        
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    • 1989(Z1): 101-102.
      摘要:Single fiber rcording technique and tail flick test of rat were used in thepresent study. The unit discharges evoked by mechanical stimuli and tail flicklatency responsed to noxious heat stimuli as indices of the activity of polymodalnociceptor were examined during and after sympathetic stimulation. Stimula-tion of the peripheral end of the lumbosaeral sympathetic trunk increased thedischarges of polymodal nociceptors at first and then inhibited markedly. Thedepression of the unit discharges lasted for more than ten min. Injection of  
        
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    • 陶之理, 许光全, 李瑞午
      1989(Z1)
      摘要:为了探讨“四自”穴治疗机理,我们用辣根过氧化物酶法(HRP法),追踪其穴区传入神经元的分布及联系。实验用大白鼠34只。在“四白”穴区注入10—20%的HRP20微升。存活24—48小时,用2%多聚甲醛及l.25%戊二醛磷酸盐缓冲液进行心脏灌流。动物死后将双侧三叉半月神经节、双侧交感颈上神经节、脑干等取出存放于30%蔗糖液内,冰冻切片后进行成色反应,观察三叉半月神经节、脑干及颈上神经节内的标记细胞及纤维。  
        
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    • 1989(Z1)
      摘要:In order to probe into the mechanism of Si-bai point for treatment abovediseases. we adopted the HRP method tracing the distribution and connectionsof the Si-Bai point. Application of 10-20% HRP 20 μl solution was injected into the Sibai po-int, 34 albumen rats were used. After a survival time of 24-48 hours, theanimals were sacrificial and their hearts were perfused with 2% paraformalde-hyde solution in 0. 1M phosphate acid buffer PH 7. 4, the semi-lunar ganglionof trigeminal nerve and upper cervical ganglion of sympathetic nerve, brainstem were cut and lay up in the 30% sucrose solution in freezer over night,and freezing section 40μm, obseryed the labeled cells in the semi-lunar ganglion,upper cervical sympathetic ganglion and brain stem.  
        
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    • 针刺镇痛在中枢神经系统的作用-2-脱氧葡萄糖方法的研究

      黄登凯, Peter J.Hand, 刘占鳌, 张殿明
      1989(Z1)
      摘要:应用[(14)C]-脱氧葡萄糖(2-DG)定量方法研究针刺时的中枢作用,清醒大白鼠16只,分为5组:(1)痛刺激组3例,(2)痛刺激+单侧针刺“足三里”、“上巨虚”穴5例;(3)单侧针刺组3例;(4)痛刺激+针刺+纳洛酮4例;(5)对照组2例。所有实验动物均按Sokoloff的方法处理,实验结果如下:痛刺激后在许多局部脑区的葡萄糖代谢率(LCMRG)有明显升高,如脊髓背角,中央导水管周围灰质腹侧份,楔状核、尾状枝头部背侧份、皮质第Ⅱ体感区。(2)痛刺激加针刺后,在上述脑区的葡萄糖代谢率明显下降,但在重体后叶其  
        
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    • 1989(Z1): 104-105.
      摘要:The quantitative[(14)C] deoxyglucose (2DG) method was employed to studythe central efffects of acupuncture. Sixteen unanesthetized, restrained ratswere injected with 2-DG and received either (1) intermittent noxious thermal  
        
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    • 王庆平, 黄登凯, 李宽孍
      1989(Z1): 105-106.
      摘要:本文采用定量2-脱氧葡萄糖(2-DG)方法研究辐射热痛刺激和双侧“足三里”、“三阴交”穴位刺激对中枢神经系统各结构的葡萄糖代谢率的影响。结果如下: 1.电针使甩尾反射痛阈升高。 2.对照组、痛刺激组所观察的结构在左右两侧的葡萄糖代谢率之间均无显著差异。电针组的脊髓腰膨大部右侧背角的糖代谢率比左侧高(35.8%),左侧的丘脑腹后核、躯体感觉  
        
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    • 1989(Z1): 106-107.
      摘要:The quantitative 2-deoxyglucose (2-DG) method are used to study the effe-cts of radiate heat stimulation and electroacupuncture (EA) stimulation at bi-lateral points of Zusanli" and "Sanyinjiao" on the local cerebrcal metabolicrate of glucose (LCMRG). The results were as follows: 1. The pain threshold of tail flick reflex was elevated after EA. 2. No significant difference was found between the two sides of all thestructures observed in the control and pain groups. In the EA group, theLCMRG of the right dorsal horn of the spinal cord in the lumbar enlargementwas higher (35. 8%) than that of the left (operational side) one, and the  
        
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    • 电针、手捻针对正中隆突及视上核细胞化学成份的影响

      葛子, 王志英, 贾林
      1989(Z1)
      摘要:本实验重点研究了电针、手捻针对下丘脑一垂体系统影响,为针灸治疗广泛应用提供理论基础。本实验选用了健康、成年、雄性大白鼠246只。随机分成电针组、手捻针组及对照等三组。两种针刺30分钟后,分别测定痛阈,其痛阈值比对照组显著增高。两种针刺组正中隆突内毛细血管壁的葡萄糖6磷酸酶(G6 Pace)及碱性磷酸酶(ALPace)反应都要比对照组有显著增强。其毛细血管网丛的分布及密度都要比对照组致密,范围大。  
        
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    • 1989(Z1): 107-108.
      摘要:The effects of original and clectroacupuncture (OA, EA) upon hypothalamo pituitarysystem was made for providing the theoratical basis in further wideapplication of acupuncture treatment. 246 healthy, adult and male rats were selected in this experiments. Itwas divided into OA, EA and control at random. The painthreshold were me-asured 30 minutes after both kinds of acupuncture, they were elevated signifi-cantly than that of the control.  
        
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    • 宋朝佑, 刘文彦, 杨俊, 林葆诚, 朱鹤年
      1989(Z1)
      摘要:本工作以钾离子透入法引起大鼠甩尾反应的电流强度(mA)为痛反应指标,观察了侧脑室注射催产素(OT)及抗催产素血清(AOTS)对大鼠基础痛阈和电针镇痛效应的影响。侧脑室注射50ngOT后60min内,大鼠基础痛阈比注药前增加20.0±3.7~37.6±5.9%(M±SE),与注射生理盐水组的基础痛阈相比,有非常明显的增高(P<0.01~0.001)。侧脑室注射OT后60min电针期内,痛阈增加138.7±14.8~233.7±9.7%,注射生理盐水电针组痛阈值增加80.5±21.8~91.2±19.6%,这两组相比有显著差异(P<0.05~0.01)。OT增强电针镇痛  
        
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    • 1989(Z1)
      摘要:The effect of intraventricular injection (ICV) of oxytocin (OT) and anti-OT serum (AoTs) on the basal pain threshold and electro-acupuncture analge-sia in rats was investigated in this study. Using the potassium iontophoresistail-flick for measuring pain. The increase of 20. 0-37. 6% in the basal painthreshold was observed within 60 mia after OT injection (50 ng), and it wasmuch more effective than that of the saline injection (P<0. 01 or 0. 001). Theincrease of 138. 7-233. 7% was produced by electro-acupuncture (EA) within 60rain after 50 ng OT administration (P<0. 05 or 0. 01 compared with saline EA).  
        
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    • 林葆诚, 杨俊, 宋朝佑, 刘文彦, 王成海, 朱鹤年
      1989(Z1): 109-110.
      摘要:已有报道,精氨酸加压素(AVP)可以提高动物的基础痛阈。本实验以钾离子透入—甩尾反应为痛指标,观察了大鼠脑室注射AVP及其抗血清对电针足三里的镇痛效应的影响,并采用放射免疫分析法测了电针时脑内AVP含量的变化,探讨AVP在电针镇痛中所起的作用。 1.大鼠侧脑室注射AVP后60min内,基础痛阈提高30~70%,与对照组相比差异显著(P<0.05或0.01)。注射AVP后立即电针,在电针60min内痛阈升高80~350%,对照组痛阈升高50~150%,两组有显著差异(P<0.05或0.01)。  
        
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    • 1989(Z1): 110-111.
      摘要:It was reported that arginine-vasopressin (AVP) could enhance the basalpain threshold and acupuncture analgesia. In this experiment, taking potassiumionotophoresis tail-flick for measuring pain, the effects of intraventricularinjection (ICV) of AVP and anti-AVP serum(AVPS) on the electro-acupuncture(EA) analgesia were observed, and the content of AVP in brain was measuredby radioimmunoassay (RIA).  
        
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    • 杨俊, 宋朝佑, 林葆城, 王成海, 刘文彦
      1989(Z1): 111-112.
      摘要:本工作采用损毁、刺激PVH,结合行为测痛(钾离子透入一甩尾区应)及AVP和OT的放射免疫测定(RIA),初步探讨PVH参与痛觉调制和电针镇痛的机制。 1.电解损毁SD大鼠双侧PVH后24小时,基础痛阈显著降低电针两侧足三里的镇痛效应也明显减弱。电针停止后镇痛持续时也缩短。 2.用电刺激SD大鼠右侧PVH,基础痛阈较对照组明显升高,电针足三里的镇痛效应增强。刺激PVH的强度与电针镇痛效应之间有明显的量效关系。以1μl谷氨酸钠在10min内缓慢注入PVH,注射后15min,动物的基础痛阈升高,电针镇痛效应也明显增强,两者均有明显的量效关系。  
        
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    • 1989(Z1)
      摘要:The present experiment attempts to searching the mechanism that PVHeffects on EA analgesia by using of lesioning, simulation of PVH, radioimmu-noassay of neuropeptides combining with the potassium iontophoresis tail-flickfor measuring pain. 1. Lesions of PVH could reduce the basal pain threshold, depress EAanalgesia and make the analgesia maintaining time shorter. 2. Electrical stimulation of PVH could elevate basal pain threshold andEA analgesia more intensive. These effects were dose-related. Similar toelectrical stimulation, injection of 1μl L-sodium glutamite into PVH could alsoelavate the basal pain thrhseold, supress the effect of electro-acupuncture andthese results had a relationship between dose and effect.  
        
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    • 宋朝佑, 刘文彦, 林葆城, 杨俊, 朱鹤年
      1989(Z1)
      摘要:为探讨OT和AVP增强电针镇痛与脑内阿片肽镇痛系统之间的关系,本工作观察了大鼠侧脑室注射抗β-内啡肽血清(AEPS)和抗强啡肽血清(ADYNS)对OT和AVP增强电针镇痛效应的影响。本实验中电针的穴位是双侧“足三里”,电针频率为18Hz。以钾离子透入—甩尾反应为痛指标。  
        
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    • 1989(Z1): 114-115.
      摘要:In order to clarify the relationship between the analgesic effect of oxyto-cin(OT) and arginine-vasopressin (AYP) and that of opiate peptides, weundertook to study the effect ef ICV of anti-β-endorphin serum(AEPS) andanti-dynorphin serum(ADYNS) on EA analgesia by OT and AVP. The point"Zusanli" was stimulated by electro-acapuncture, the frequency was 18Hz, thepain threshold was measured by potassium iontophoresis tail-flick.  
        
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    • 杨俊, 宋朝佑, 王成海, 林葆城
      1989(Z1)
      摘要:文献报道精氨酸加压素(AVP)难于通过血脑屏障,但无论经外周还是中枢给予AVP均可发挥镇痛作用。本工作通过脑室和静脉注射放射性碘标记的AVP((125)I-AVP),观察(125)I-AVP),观察(125)I-AVP在体内的分布及电针对其分布的影响。 (125)I-AVP在体内的分布及电针对其分布的影响。 (125)I-AVP用氯胺T法标记。过量抗体试验结合率为92.5%。雄性SD大鼠分为静脉注射对照组(IV-C组),静脉注射电针组(IV-EA组)、脑室注射对照组(ICV-C组)和脑室注射电针组(ICV-EA组)。动物经脑室注射(125)I-AVP用氯胺T法标记。过量抗体试验结合率为92.5%。雄性SD大鼠分为静脉注射对照组(IV-C组),静脉注射电针组(IV-EA组)、脑室注射对照组(ICV-C组)和脑室注射电针组(ICV-EA组)。动物经脑室注射(125)I-AVP100000cpm(6μl)或尾静脉注射100000cpm(1ml),对照组在注射后20min断头取血、肾脏、垂体、脊髓和脑区等标本,分别测定其放射性(cpm),电针组在注射后立即电针两侧足三里,20mm后断头,取标本测定放射性。  
        
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    • 1989(Z1)
      摘要:This experment attempts to measure the content of (125)I-labeled AVP indifferent tissures and to study the effect of electro-acupuncture (EA) on thedistribution of labeled AVP in rats. AVP was labeled with (125)I-labeled AVP indifferent tissures and to study the effect of electro-acupuncture (EA) on thedistribution of labeled AVP in rats. AVP was labeled with (125)I using the choramine T method. Male SD ratswere divided into IV-Control (Ⅳ-C), Ⅳ-EA, ICV-control (ICV-C) and ICV-EA groups. (125)I using the choramine T method. Male SD ratswere divided into IV-Control (Ⅳ-C), Ⅳ-EA, ICV-control (ICV-C) and ICV-EA groups. (125)I-AVP 100000cpm was injected into the lateral ventricule orthe tail vein. 20min. after injection, the rats were decapitated and the conce-ntration of AVP in blood, kindey and different regions of brain tissure weremeasured. EA of 20 mtn was used in the IV-EA and ICV-EA after injection.  
        
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    • 安定加强小鼠的肾上腺皮质激素镇痛作用

      黎海蒂, 张问德
      1989(Z1)
      摘要:本实验腹腔注射安定等多种影响γ-氨基丁酸(GABA)受体和代谢的药物,采用痛阀测定和荧光分光光度法测定小鼠脑区5-HT含量的方法,观察安定在小鼠ACTH镇痛中的作用及其作用机理。实验结果如下:(1)腹腔注射安定(8mg/kg),能显著加强ACTH镇痛作用(P<0.001),这种加强作用至少可维持90分钟;(2)把GABA受体阻断剂印防己毒素(6mg/kg),注入小鼠腹腔,可显著剥弱ACTH镇痛作用(P<0.001),并且印防己毒素可翻转安定加  
        
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    • 1989(Z1): 117-118.
      摘要:In the present study we injected diazepam, r-aminobutyric acid (GABA)receptor antagonist——picrotoxin and GABA synthesis inhibitor——isoniazid into the intraperitoneal (ip). Mice painful threshold and serotonin (5-HT)content in mice brain were measured by spectrofluorometric assay, the effectof diazepam on ACTH analgesia was obstraeted. The possible mechanisms ofdiazepam effect were studied.  
        
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    • 猫皮层体感区内脏大神经代表区细胞内电位的记录

      滕国玺, 王雪峰, 刘素珍, 刘钊, 马晓玲
      1989(Z1)
      摘要:本实验共观察8只猫,15个皮层内脏神经相关神经元和9个胶质细胞。神经元静息电位为40~60my,有自发放电并于刺激内脏大神经时出现动作电位。刺激内脏大神经强度弱时可导出EPSP,随刺激增强出现单个或多个峰电位,其后尚跟随IPSP。静脉注射杜冷丁后,峰电位消失,只存有EPSP。刺激丘脑腹后外侧核,从代表区细胞可导出顺胞体电位,刺激对侧S_1区时,可于细胞导出逆胞体动作电位。  
        
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    • 1989(Z1)
      摘要:Experiments were carriad out on 8 cats. Using conventional intracellulartechniques, intracellular potentials of the cells located in representation ofthe greater splanchnic nerce (SPN) were recorded. The results obtained showed that resting potentials (RP) and action potent-ials (AP) of the cells were 40—60mV and 20—45mV(overshoot of the AP)respectively. RP of the gila were a bit higher than the neurons, namely 60—80mV. AP was'nt able to induce in the glia.  
        
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    • 张瑞德, 蔡奎, 那杰, 马晓玲, 刘淑珍, 王欢, 滕国玺
      1989(Z1)
      摘要:本文以强电流刺激猫内脏大神经传入纤维引起的丘脑后核单位放电为内脏痛的指标,观察电刺激中脑导水管周围灰质(PAG)对内脏痛的影响。在20只猫实验中的丘脑后核区,共观察了58个反应单位,其中除了6个反应单位的内脏大神经诱发单位放电不受PAG影响外。其余52个反应单位都受到抑制。在受到抑制的反应单位中,46个反应单位放电的波幅立即恢复,可达刺激前的波幅水平。明显的抑制效应发生在PAG刺激停止后30~150毫秒期间。有4个单位诱发放电出现两个成分的反应。抑制作用可分为即时抑制和长时程两种类型。静脉注射纳洛酮(1.0mg/kg)对PAG的二种抑制均有桔抗作用。其作用大约在注药后3~5分钟开始,25~27分达到高峰,43分钟拮抗作用逐渐消失。  
        
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    • 1989(Z1): 120-121.
      摘要:The effects of stimulating PAG on the nociceptive neuron discharges of POnucleus evoked by stimulating the splanchnie nerve in cat were studied. Twokinds of inhibitory action were observed. One is called early phase or promptinhibition phase which occurs promptly within 30ms to 150ms after stimulationof PAG. The other is called slow-phase or sustained inhibition which occurs  
        
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    • 电刺激黑质对猫丘脑后核群内脏大神经诱发放电的影响

      时利德, 张战, 蔡奎, 沙磊, 王欢, 马晓玲, 滕国玺
      1989(Z1): 121-122.
      摘要:本工作通过观察电刺激黑质对内脏大神经伤害性刺激丘脑后核群(PO)产生的诱发放电之影响,探讨了黑质在调节内脏痛方面的可能作用。实验用成年猫14只,不拘性别,术后在制动人工呼吸下观察。在14只猫的FO核区共找到内脏伤害性感受单位42个。其中41个单位为一簇诱发放电,潜伏时为69.3±23.6ms,另一个为两簇诱发放电,潜伏时分别20ms和210ms。当以电刺激黑质为条件刺激。电刺激内脏大神经为检验刺激进行观察时发现,42个单位中有23个单位(占52.5%)在电刺激黑质后的15~150ms,最长达845ms时间内,内脏大神经伤害性刺激在PO核产生的诱发放电消失,此为即时完全抑制单位。有17个单位(占42.5%)在刺激黑质后,内脏大神经PO诱发放电消失应持续1~6分钟,此为长时程具有后作用的抑制单  
        
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    • 1989(Z1)
      摘要:The experiments were carried out in 14 cats. The unit discharges evokedba strong electrical stimulation of the great splanchnic afferent nerve fiberswere recorded at 42 units of the posterior nucleus group of the thalamus (PO).A short train of electrical stimulation of the substantia nigra (SN) couldinhibit the evoked discharges by splanchnic afferents at 40 units of PO. TheSN-induced inhibitory effects presented patterns: "instant inhibition", whichappeared as soon as stimulation of SN ended and lasted less than 450ms or845ms, and "long time lasting inhibition", which appeared as soon as stimula-tion of SN ended and lasted for 1--17 minutes. Moreover, evoked discharges  
        
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    • 陈永跃, 黄仲荪
      1989(Z1)
      摘要:作者用胃窦部电活动的两种波形,束状波和慢波作为胃运动功能指标观察了电针对胃运动的影响。1)在清醒家兔电针双“足三里”穴对胃电两种波形的影响都取决于电针前胃电的活动水平,即电针对活跃的胃电表现抑制作用,对低水平的胃电表现兴奋作用,而对适中的胃电则没有影响。电针“脊中”穴对胃电没有影响。2)用恒定强度电针双“足三里”穴对肌  
        
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    • 1989(Z1): 123-124.
      摘要:The present paper used two kinds of antral electril activity: burst of spikesand slow wave, as indicator of antrsl mechanical contraction studied the effectof electro-acupuncture Zusanli point on the movement function of stomach inrabbit. (1) In conscious rabbit, electro-acupuncture "Zusanli" point coulddecrease both the frequency of the burst activity and the amplitude of slowwave as in their higher level, and increase them when they are in lower level,  
        
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    • 刺激兔孤束核诱发胃电活动变化及针刺效应观察

      张能, 陈永跃, 陆杰, 黄仲荪
      1989(Z1)
      摘要:在27只麻醉制动的兔身上观察记录了电刺激孤束核区诱发胃电活动为变化和电针效应。实验结果表明:电刺激孤束核可诱发胃窦平滑肌电活动发生明显变化,以兴奋为主,并有一定后效应。切断双侧颈迷走神经或注射阿托品后,诱发电位增强反应消失,提示胆碱能纤维参与了这种兴奋性效应。刺激孤束核区时引起胃电抑制的途径比较复杂,在切断双侧颈  
        
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    • 1989(Z1): 124-125.
      摘要:In 27 curarized conscious rabbits with artificial positive ventilation, theauthors studied the effects of electric stimulation of Nucleus Tractus Solitarius(NTS) area on the antral electrical activity of stomach and the effect ofelectro-acupuncture of "Zusanli" points. Electrical stimulation of NTS areacould induce significant change in anlral electric activity, mainly excitatoryand with certain after-effect. The induced excitatory electric activity disa-ppeared both by the section of bilateral vagus nerves or atropinization of the  
        
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    • 黄仲荪, 刘念森, 钟声, 张能, 陆杰
      1989(Z1)
      摘要:实验在164只家兔身上进行。目的在于了解腹部迷走神经(AVN)的冲动如何从外周传向延髓;在延髓内投射分布的特征;由AVN诱发的内脏一躯体肌反射(VSR)的性质以及针刺对它的影响。 1)、用单一方波电(30v,0.5ms)的刺激VAN胃支,在颈部迷走神经干上可引导到两组综合动作电位:传速为10.4—24.4m/s的快波和0.9——1.7m/s的慢波,后者较为稳定。 2)、用金属粗电极(尖端直径为50μ左右)可在延髓内引导到一个由AVN诱发的长潜伏期(19.2±222.2ms,X±SD,下同)的M形电位,时程较长,约100ms左右。反映了AVN的冲动主要由细的纤维传导并在延髓发生多实触联系。  
        
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    • 1989(Z1): 126-127.
      摘要:The study was carried out on 164 healthy rabbits using electroneurophysi-ology and neuroanatowy methodology. The purpose of the study was to inve-stigate that how inputs from abdominal vagus nerve projecte to medullaoblongata, the electrophysiologieal characteristics of the projection of abdominalvagal inputs, the characteristics of VSR induced by stimulation of abdominalvagus nerve and the influence of acupuncture on VSR.  
        
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    • 穴位针感感受器及其传入纤维类别

      候宗濂
      1989(Z1): 127-128.
      摘要:Blix1882年在皮肤上发现温点冷点,作为躯体感觉生理学的先驱记入史册,而我国早在纪元前几百年就发现了穴位这一针感点,是对现代生理学的一大贡献! 穴位处为针感感受器,我们经过多方面的研究工作确定它主要是深部感受器,因穴位所处环境不同存在着不同的深部感受器。肌肉丰富处以肌梭为主,肌腱接头处以腱器官为中心周围多肌梭,肌腱或其附近多环层小体,关节囊处以慢适应感受器较多,头皮,任脉、督脉多为游离神经末梢。  
        
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    • 1989(Z1): 128-131.
      摘要:An acupuncture point is a point of needling sensation. In 1882, Blix disco-vered warm and cold spots in the human skin. For this discovery, he wasregarded as the pioneer of somatosensory physiology in the modieal literature.However, as early as hundreds of years before Christ, the sensory points ofacupuncture had already been described in the literature of Chinese traditionalmedicine, which was an important contribution to the modern physiology.  
        
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    • 肌梭作为针感感受器可能性的进一步探讨

      樊小力, 刘广斌, 黄洛秀, 许敏
      1989(Z1)
      摘要:肌肉丰厚处体针穴位的针感感受器主要是肌梭。针刺如何能使肌梭发生兴奋?在针刺条件下肌梭传入放电的波形特征如何?我们用分离单一肌梭的方法进行了研究。实验用蟾蜍为对象。用空气隔绝法记录肌梭传入神经的电信号,进行功率谱分析,实验结果如下: 共分离单一肌梭38个,其长度平均为4.31±0.35mm,赤道部直径平均为109.82±4.7μ,而2寸针灸针其针杆部直径为484.21±1.97μ,针尖部直径为19.4±2.71(n=20)。实验中连续观察2分钟内肌梭的传入放电变化。见到针刺前肌梭自发放电频率为1.94±0.39个/秒,  
        
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    • 1989(Z1): 131-132.
      摘要:How could the spindle be activaled by acupuncture? How about the chara- cteristic of the wave shape of spindle afferents during acupuncture? To counterthese questions we have made some research with isoteted single spindle. Toadwas the subject in our experiment.  
        
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    • 王克模
      1989(Z1)
      摘要:我们自1981年开始采用钨丝微电极法以针感及其伴随的传入单位放电为指标对人体正中神经、尺和胫神经支配的穴位的所在部位、穴位的大小进行了测量。对穴位感受器和针感传入纤维类别进行了研究。本工作还应用了BASIC语言编制的FFT程序分析了手针时单位放电平均功率谱,首次分析了手针感和传入纤维类别间的关系。结果表明: 1.除手部穴位外,体针穴位主要位于皮下深层。正中神经支配的穴位在皮下0.9—2.4cm处。尺神经支配穴位多在皮下0.9—1.5cm范围内。胫神经支配穴位多在皮下1.5—2.5cm处。位于皮内浅层穴位的大小多为0.5×0.5×0.3cm3。位于深部正中神经支配穴位大小为1—2(长)×0.5—1.5(宽)×0.3—0.8cm3。位于深部正中神经支配穴位大小为1—2(长)×0.5—1.5(宽)×0.3—0.8cm3。尺神经支配穴位平均大小为1.8×1.4×0.66cm3。尺神经支配穴位平均大小为1.8×1.4×0.66cm3。腔神经支配穴位平均为1.76×0.7×0.87cm3。腔神经支配穴位平均为1.76×0.7×0.87cm3。  
        
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    • 1989(Z1): 133-134.
      摘要:The microelectrodes were made of tungsten wire with a diameter of 196μm.After the tips of microelectrodes were etched and insulated by FS-46. The uninsulated part of the tip was less that 40μm in length; the tip diameter was1--4μm and its impedance tested ranged from 100KΩ. to 500 KΩ. The tip ofreference electrode was little bigger than that of recording electrode, and itsuncoated tip length was 1--2mm.  
        
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    • 针刺镇痛传八纤维的研究

      唐敬师, 袁斌
      1989(Z1)
      摘要:本文总结了我们研究室自一九七九年以来关于针刺镇痛传入纤维的一系列研究工作。一、以伤害性电刺激腓神经近端诱发家兔反射性下颌运动为痛反应,在该神经远端以连续电脉冲刺激模拟穴位电针(频率5次/秒),用逐渐增加电针强度的方法,观察了不同类型神经纤维的镇痛作用。结果表明电针时兴奋的纤维越细镇痛作用越强,即兴奋ⅠⅡ类的作用小于兴奋Ⅰ、Ⅱ、Ⅲ类者,后者又小于兴奋Ⅰ、Ⅱ、Ⅲ、Ⅳ类者。二、在兴奋四类纤维产生明显镇痛作用的基础上,用奴佛卡因选择性阻滞细纤维(Ⅲ、Ⅳ类)的传导后,镇痛作用显著减弱,持续时间也缩短,表明粗细纤维同时兴奋时镇痛作用的显著增强是细纤维兴奋的结果,而不是兴奋了更多粗纤维的结果。  
        
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    • 1989(Z1): 135-137.
      摘要:This paper is a summary of a series of researches carried out in this laboratory since 1979 on the afferent fibers responsible for the acupunctureanalgcsia. 1. The analgesic effects produced by activation of different groups ofafferent fibers during electro-acupuncture were observed in the rabbit. Thejaw-opening reflex induced by noxious electric stimulation to the proximalperoneal nerve was used as a pain response. The distal portion of the samenerve was stimulated electrically with repeated pulses (5Hz) to simulate electro-acupuncture of the points. The results indicated that the smaller the fibers  
        
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    • 张晓泉, 江赛男, 牛汉璋
      1989(Z1): 137-138.
      摘要:本实验对腓肠神经和腓肠肌神经传入排放于脊髓背角的会聚情况及电针肌神经对皮神经诱发的会聚神经元C反应的影响进行了观察。实验在清醒麻痹的大白鼠进行,在脊髓腰膨大处记录腓肠神经诱发的背角神经元,用单一方波分别刺激腓肠神经和腓肠肌神经,对找到的133个腰段脊髓背角神经元进行分析,其中124个细胞可同时被腓肠神经和腓肠肌神经电刺激激活,称之为躯体-躯体会聚神经元。根据神经元对皮神经粗(A类)和/或细(C类)纤维和肌神经粗(A类)和/或细(C类)纤维的传入反应,可以进一步分为五个类型:①A-A型,②A-AC型,③AC-A型,④AC-AC型和⑤C-C  
        
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    • 1989(Z1): 138-139.
      摘要:The purpose of our experiments is to show the convergent patterns ofinputs from skin and muscle onto the dorsal horn ceils of rat and the effectsof stimulating musclar nerve onto the responses of WDR (wide dynamic range)ncurones.  
        
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    • C纤维传入对电针镇痛并非必需,而对DNIC则是必需的

      包红, 周正锋, 于英心, 韩济生
      1989(Z1): 139-140.
      摘要:电针镇痛究竟通过何种纤维传入,至今仍存在争议,范少光等提示C纤维不是电针镇痛的主要传入纤维。本工作用电生理方法在雄性大鼠(300—450g体重)上进一步深入分析。 1.脊髓背角广动力(WDR)神经元对伤害性电刺激(3倍C纤维阈值)发生两串反应,吗啡对其长潜伏期放电有抑制作用,该作用可被纳络酮反转;而对其短潜伏期放电无明显影响。 2.电针一侧“足三里”和“三阴交“,WOR神经元的长潜伏期反应明显下降,为电针前的42.8±5.1%(n=17)。  
        
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    • 1989(Z1): 140-141.
      摘要:A lot of work had been done to explore the mechanism of acupuncture anal-gesia (AA), but there have been some important questions to be dclarified. Forcxample, what kind of afferent fiber plays an important role in AA? In orderto solve this question, we applied capsaicin topically on sciatic nerve and usedthe techniques of extracellular recording and nerve trunk recording.  
        
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    • 王晓民, 周仲福, 韩济生
      1989(Z1)
      摘要:本工作以2.0~2.6公斤的雄性家兔为实验对象,以甩头或甩尾反应的潜伏期ERL作为观测指标,观察了电针“足三里,和“昆仑”镇痛的适宜频率和纳洛酮对不同频率电针镇痛的阻断作用。结果表明,不论头部或尾部测痛都是2~15Hz的镇痛作用最强,其次为15Hz≥2Hz>30Hz>60Hz≥100Hz。将各频率组的头部电针有效率与尾部电针有效率分别进行x2检验,发现两者之间的差异无统计学意义。将头部和尾部的电针有效率平均起来更清楚地表明2-15Hz的电针镇痛效果最好,60Hz(和/或100Hz)的最差。60Hz组与2~15Hz组相比,  
        
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    • 1989(Z1)
      摘要:Male rabbits of 2. 0-2. 6kg were used. Nociception was assessed by measuringthe latency of the escape response (ERL) elicited by strong radiant heat focu-sed on the skin of the nostrils or on the tail. Electroacupuncture (EA) wasapplied via needles inserted into the, acupoint "Zusanli" and "Quenlun". A 50%increase in ERL at the end of 10 rain EA stimulation was considered as positiveresponse in EA analgesia. The effectivenese of EA analgesia was determinedusing EA of different frequencies, ranging from 2, 2--15, 15, 30, up to 60 and100Hz, with the intensify of EA being fixed at 2 volts (2. 24±0. 11 mA).  
        
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    • 孙少丽, 韩济生
      1989(Z1)
      摘要:以往的工作表明,给大鼠低频或高频电针在脊髓中分别释放出脑啡肽或强啡肽,产生镇痛效果。本工作用交叉耐受方法对此进行实验。结果表明:(1)给大鼠2Hz电针6小时,镇痛作用逐渐降低导致耐受后,100Hz电针仍有明显的镇痛作用;100Hz电针耐受后,2Hz电针仍然有效。说明低频和高频电针镇痛相互之间无交叉耐受。(2)100Hz电针耐受后,K  
        
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    • 1989(Z1)
      摘要:The effects of different frequency electroacupuncture (EA) tolerance onthe analgesia of delta and kappa agonists were studied on rats. The presentresults show: (1) There was no cross tolerance between 2Hz and 100Hz EA.In 2Hz EA tolerant animals the analgesic effect of 100Hz EA still existed andvice versa. (2) In 100Hz EA tolerance rats the analgesia of introthecal (ith)dynorphin A (1-13), a kappa agonist, reduced significantly while that of ith[D-pen2, D-pen2, D-pen5] enkephalin (DPDPE), a delta agonist, remained unchanged.  
        
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    • 高而威, 王克威, 韩济生
      1989(Z1)
      摘要:我们以往的工作表明,脑内血管紧张素Ⅱ(AⅡ)作为一种抗阿片物质参与吗啡耐受和电针耐受的形成。本工作探讨在此过程中脑内血管紧张素(Ang)基因表达是否加速。采用酚抽提法取大鼠脑组织总RNA,使用人工合成的Ang cDNA探针进行打点杂交。放射自显影结果表明,多次皮下注射吗啡或连续数小时电针的大鼠脑Ang mRNA含量明显升高。在IBAS  
        
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    • 1989(Z1): 144-145.
      摘要:Previous findings in our laboratory suggest that angiotensin Ⅱ (AⅡ) in thebrain is a powerful antagonist to the analgesic effect elicited by morphine andelectroacupuncture (EA) and plays an important role in the development ofEA and morphine-toterance. While the content of AⅡ-ir in the brain increaseddramatically in the rats subjected to repeated administration of EA or morphine,it was interesting to see whether the expression of angiotensinogen gene wasalso accelerated to cope with the increase in release. The samples of total RNAextracted from the brains of the rats were blotted to the Gene Screen membraneand hybridized with the synthetic (32)P end-labeled oligonucleotide DNA probe,  
        
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    • 王晓民, 韩济生
      1989(Z1)
      摘要:本工作以2.0—2.6公斤的雄性家兔为实验对象,在一侧后肢相当于“足三里”和“昆仑”穴的部位进针,用辐射热照射家兔鼻唇部皮肤引起甩头的潜伏期(ERL,S)作为伤害性反应的指标。将血管紧张素Ⅱ(AⅡ)或AⅡ的抗血清注入中脑导水管周围灰质(PAG)或伏核内,观察AⅡ在电针镇痛和电针耐受中的作用。结果表明:PAG注射AⅡ0.1μg可明显对抗电针(2-15H_2,2 V,20min)的镇痛效应(P<0.01,ANOVA,n=14),而伏核内注射等量  
        
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    • 1989(Z1): 145-146.
      摘要:Male rabbits of 2. 0-2. 6kg was used. Nociception was assessed by measur- ing the latency of the escape response (ERL) elicited by strong radiant heatfocused on the skin of the nostrils. Eleetroacupuncture (EA) stimulation wasapplied via acupuncture needles inserted into the acupoint Zusanli and Qunlun,located near the knee joint and ankle joint respectively. The analgesic effectof EA (2-15Hz, 2V, 20min) could be blocked by injecting angiotensin Ⅱ (AⅡ)  
        
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    • 大鼠脑内血管紧张素Ⅱ参与电针耐受的证据

      王克威, 韩济生
      1989(Z1)
      摘要:采用辐射热甩尾测痛法,将血管紧张素Ⅱ(AⅡ)抗体或AⅡ受体拮抗剂Saralasin注入大鼠侧脑室以去除脑内AⅡ的作用,观察其对电针耐受动态过程的影响。同时,放免测定了电针耐受大鼠脑脊液(CSF)中AⅡ的含量变化。实验在大鼠双后肢相当于“足三里”和“三阴交”部位给予6轮电针(每轮为电针30分钟,休息30分钟)或6小时持续电针,电针刺激的频率2-15Hz,,幅度3伏。结果表明,侧脑室注射AⅡ抗体(IgG)20μg或Saralasin20μg可明显推迟连续6轮电针造成的电针耐受(P<0.05,ANOVA)。给大鼠连续5轮电针造成耐  
        
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    • 1989(Z1)
      摘要:The purpose of this study was to examine the involvement of brain angio-tensin Ⅱ (AⅡ) in the development of tolerance to electroacupuncture (EA)analgesia in rats. Antibodies against AⅡ (AⅡ IgG), or saralasin (antagonistof AⅡ) were administered intracercbroventricularly (icv) to prevent the endo-genously released AⅡ fram activating AⅡ receptors, and the dynamic courseof the development of electroacupuncture tolerance was monitored. EA tolerancewas induced by 6 successive sessions of EA stimulation (2-15Hz, 3v, 30min,  
        
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    • 曹威, 周仲福, 韩济生
      1989(Z1): 147-148.
      摘要:CCK-8是目前所知作用最强的一种抗网片肽。我们曾经报告,只要向大鼠脑室注射 1-4ng的CCK-8即可显著对抗吗啡镇痛和电针镇痛。为探讨CCK-8的中枢抗阿片作用部位及种属特异性,我们将CCK-8注入家兔PAG,观察其对吗啡镇痛和电针镇痛的影响。  
        
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    • 1989(Z1): 148-149.
      摘要:We have reported that intracerebroventricular (i. c. v.) injection of 1-4 ngof CCK-8 to the rat produced a remarkable antagonistic effect on morphineanalgesia. In order to study the species specificity and the site of action.CCK-8 was microadministered to the PAG of the rabbit, and its influence onmorphine analgesia and electroacupuncture analgesia was observed.  
        
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    • 王峻峰, 任民峰, 韩济生
      1989(Z1)
      摘要:本文重点观察了阿片拮抗剂纳洛酮阻断上述阿片类物质镇痛作用所需的剂量。 1)将大鼠分为四组:生理盐水组、纳洛酮0.02、0.1和0.5mg/kg组。开始各组均脊髓蛛网膜下腔(ith)注射强啡肽2.5nmol、吗啡7.5nmol混合溶液,10分钟后测得四组的甩尾反应潜伏期(TFL)变化在94±19~109±22%之间。然后各组分别皮下注射盐水10ul、纳络酮0.02、0.1和0.5mg/kg,连续观察50分钟。结果表明,随着纳洛酮剂量增加,阿片镇痛作用逐渐减弱,呈明显的量效关系、三个纳洛酮组与生理盐水组相比均有极显著性(P<0.01)。  
        
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    • 1989(Z1): 150-151.
      摘要:The present study deals primarily with the antagonistic effect of Naloxone(NX) against mutual potentiation of morphine (Mor), mek-enkephalin (MEK)and dyno phin (Dyn) in their analgesic effects. (1) The rats were divided into 4 groups, ie. NS, NX 0. 02, 0. 1 and 0. 5mg/kggroups. A mixture of Dyn 2. 5noml and Mot 7. 5noml was injected in thebeginning via intrathecal cannulae into each rat. Percentage incrcase in TFLin all 4 groups was between 94±19% and 109±20% 10rain later. After thateach grcup was injected subcutaneously NS, NX 0.02, 0.1 and 0.5mg/kg respe-ctively and was observed continuously for 50min. The results suggest that the  
        
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    • 朱丽霞, 黎春元, 方宗仁, 史清瑶, 吉长福
      1989(Z1)
      摘要:本文系统研究了5-HT下行抑制在针刺镇痛中的作用,及其与内阿片肽及P物质的可能关系。一、本实验采用毁损5-HT能神经元胞体密集的中缝大核(NRM)、腹腔注射对氯苯丙氨酸抑制5-HT合成及用5.7-双羟色胺化学毁损5-HT末梢,以及鞘内注射或微电泳导入二甲麦角新碱阻断5-HT受体等手段,从各个环节减弱脑内5-HT的作用,都可减弱针刺镇痛效应,说明5-HT下行抑制在针刺镇痛中具有重要作用。  
        
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    • 1989(Z1): 152-153.
      摘要:In this paper a series of experiments on the role of serotoninergic desce-nding inhibition in AA and its potential relation to opiate-like substance (OLS)and substance P (SP) were performed. 1. We have found that the analgesic effect of acupuncture could be signi-ficantly attenuated by lesion of nucleus raphe magnus (NRM), intraperitonealinjection of para-chlorophenylalanine (PCPA), infracisternal injection of5, 7-dihydroxytryptamine (5, 7-DHT) and intrathecal or iontophoretic administra-tion of Methysergide (MSG). AII these results suggest that serotoninergic desce-  
        
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    • 电针镇痛对大鼠脑和脊髓中P物质含量水平的影响

      崔仁麟, 马春红, 周宇瑛
      1989(Z1)
      摘要:本实验研究电针镇痛作用下,脑和脊髓P物质的量的变化。对实验组大鼠进行电针并对下丘脑、脑干和脊髓的P物质进行放射免疫测定。对照组不给电针,其它处理与对照组相同。对痛阈提高组大鼠与对照组进行比较,电针组比对照组下丘脑的P物质明显降低,而脑干和腰髓部位升高。此实验表明脑干和脊髓P物质与针刺镇痛的下行性抑制亦能有联系。并对其机制作了初步讨论。  
        
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    • 1989(Z1): 153-154.
      摘要:This experiment is to investigate the electro-acupuncture analgesia on thefluctuations of substance P in brain and spinal cord. The electro-acupuncturewas given to the experimental rats and the quantity of the substance P (SP)in the hypothalamus, the brain stem and the lumber spinal cord was determinedby the radioimmunoassay. The control group was not given the electoacupunctureand the other treatments were the same as the experimental animals. Whilepain threshold increased (PTI) rats with the control were compared; the SP inthe hypothalamus of the PTI rats decreased singnificantly, however the SP in  
        
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    • 陆卓珊, 董晓彤, 张庭钧, 曹蔚鸿, 邓颖
      1989(Z1)
      摘要:我们用福氏佐剂诱发的关节炎大鼠作为病理模型,观察艾灸对患关节的压病闽,局部皮肤温度,足容积,以及坐骨神经内的和腰髓内的P一物质和亮一脑啡肽的影响,试图探索文灸治疗关节的作用机理。疗效:治疗组和对照组大鼠的局部皮肤温度、足容积(肿胀程度),两个指标的恢复情况,两组之间没有差别。治疗组在第二疗程后,与治疗前的病阈比较即有显著的憎高(P<0.01),第三疗程后,痛阐基本恢复正常。而对照组在第三疗程后,痛闹才有明显的增加(P<0.05)。表明大鼠佐剂关节炎虽有自愈的能力,但艾灸治疗有促进关节病缓解的作用,效果是明显的。  
        
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    • 1989(Z1): 154-155.
      摘要:In order to study the mechanism of moxibustion-treating arthralgia, we have observed, using the rat suffering from Freuad adjuvant arthritis as a pa-thological model, the effect of moxibustion on the pressure pain threshold, localskin temperature and foot volume of affected extremities, the levels of substa-nce P(SP) and leu-enkephalin (LEK) in the sciatic nerve and lumbar spinalcord.  
        
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    • 大鼠脑内P物质在针刺镇痛中的作用及其与脑啡肽的关系

      邓颖, 曹蔚鸿, 陆卓珊
      1989(Z1)
      摘要:实验观察了大鼠脑室注射SP拮抗剂[D-Arg1,D-Phe1,D-Phe5,D-Trp5,D-Trp(7·9),Leu(7·9),Leu(11)]-SP(简称DADPDTL)对电针镇痛效应的影响;电针刺激后大鼠脑内SP含量的变化以及脑室或腹腔注射纳洛酮后对电针引起的SP含量变化是否有影响。脑室注射20ul生理盐水电针后,痛阈升高46±10%(P<0.01),而注入DADPDTL后电针,痛阈比基础痛阈下降了21±5%(P<0.05),与电针组比较有明显差异(P<0.001)。表明DADPDTL能对抗电针镇痛效果。  
        
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    • 1989(Z1): 156-157.
      摘要:We have observed the influence of substance P-antagonist, (D-Arg1, D-Phe1, D-Phe5, D-Trp5, D-Trp(7,9), Leu(7,9), Leu(11))-SP (DADPDTL) injected intracerebroventricularly(icv) on EAA, the change of the level of SP in the brain regions of the ratduring EAA and if electroacupuncture (EA) stimulation could change the levelof SP in the brain, the naloxone (NX) is whether or not to affect the changeinduced by EA.  
        
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    • 针刺镇痛与血浆亮啡肽、皮质醇含量及中医辨证的关系

      刘忠英, 何莲芳, 吕燕燕, 王妙珍
      1989(Z1)
      摘要:本文报导在针刺治疗慢性疼痛的病例中进行的观察。病例分为阳虚与非阳虚二组。针效用划表法表示。血浆亮啡肽样免疫活性物质(LEKLIS)与皮质醇用放射免疫法测定。结果表明:1.针刺镇痛效果与血浆LEKLIS水平的变化相关(n=48,r=0.403,P<0.01)。2.阳虚病例多数针效好,血浆LEKLIS含量增加(n=22,P<0.01);非阳虚组针效较差,血浆LEKLIS含量降低(n=26,P<0.05)。二组针效有显著差异(x2=21.97,P<0.01)。3.二组病例的血浆皮质醇在针刺前后均无明显改变。  
        
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    • 1989(Z1)
      摘要:An investigation was undertaken on chronic pain patients treated with acu-puncture and differentiated into two groups, one with yang deficiency and theother without yang deficiency. The efficacy of acupuncture therapy was eva-luated by the visual analogue scale. The contents of plasma leu-enkephalinlike immunoreactive substance (LEKLIS) and plasma cortisol were measured byradioimmunoassay. It was found that the therapeutic effect of acupuncture wasassociated with changes of plasma LEKLIS before and after acupuncture. Mostpatients with yang deficiency manifested good effect and their plasma LEKLIS  
        
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    • 四氢大麻酚镇痛及加强电针镇痛的实验研究

      黄显奋, 严泓渠, 姜建伟, 刘忠英, 何晓平
      1989(Z1)
      摘要:本工作拟观察四氢大麻酚(Δ9-THC)与针刺联合应用的镇痛作用,能否既减少前者的用量,避免剧烈的降低血压等付反应,又可以加强镇痛,延长镇痛时间,并对四氢大麻酚加强电针镇痛的机制,作初步的探讨。选用2~2.5kg左右的家兔,用钾离子透入法测痛,以引起头部或前肢防御性运动反应时的最小电流强度值(mA)作为痛阈。电针取前肢一侧合谷穴,用上海G-6805电针仪输出,频率为每秒2~4次,强度以引起足趾微动而动物保持安静为度。测定痛阔的同时收集脑脊液和血液样本测定亮啡肽样免疫活性物制(LEK-LIS)的含量变化。  
        
      997
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    • 1989(Z1): 159-160.
      摘要:The present work investigated the analgesic effect of Δ9-tetrahydrocanna-binol (Δ9-THC) combined with electroacupucture (EA) and analysed the possiblemechanism of this effect.The experiment was performed on conscicus rabbits. Pain threshold wasdetermined by potassium iontophoretic dolorimetry. Electroacupuncture wasapplied at unilateral "Hegu" and "Waiguan" points. Δ9-THC (0, 1mg/kg, iv)  
        
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    • 静脉注射左旋四氢巴马汀及其同类物加强家兔电针镇痛

      吴钢, 姜建伟, 吴根诚, 曹小定
      1989(Z1): 160-161.
      摘要:左旋四氢巴马汀(L-tetrahydyropalmatine,L-THP)又称颅通定(rotundine)是临床常用的一种非麻醉性镇痛药,具有镇痛、镇静、肌松和抗心律失常等多种药理功能。本工作在家兔身上试将L-THP与电针联合应用,观察L-THP对电针镇痛的影响,比较其同类物四氢檗碱(tetrahydroberberine,THB)和左旋千金藤立定(L-Stepholidine,L-SPD)对电针镇痛的作用。旨在为临床寻找合理的针麻增效药提供实验资料。采用兔耳钾离子透入测痛法测定兔皮肤痛阈。电针一侧兔前肢的“合谷”和“外关”穴,频率3~4Hz,强度以引起足趾微动为度,持续30min。  
        
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    • 1989(Z1): 161-162.
      摘要:L-Tetrahydropalmatine (L-THP) is a non-narcotic analgesic which possessesmanifold pharmacologic effects such as analgesia, tranquitizing, antiarrhythmiaand so on. Tetrahydroberberine (THB) and L-stephotidine (L-SPD) are two ana-logues of L-THP which have been used in ctinics. In present paper, the effectsof L-THP, THB or L-SPD on electroacupuncture (EA) analgesia were observedand compared in rabbits so as to provide the laboratory information about see-king certain synergists of acupuncture anethesia.  
        
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    • 吴钢, 姜建伟, 吴根诚, 曹小定
      1989(Z1): 162-163.
      摘要:多巴胺(dopamine,DA)D_2受体的一个重要的,也是有别与DA受体的功能是调节DA的释放和代谢过程,而D_1受体与腺苷酸环化酶有密切的关系,影响着cAMP的形成。为了解D_2和D_1受体在左旋四氢巴马汀(L-tetrahydropalmatine,L-THP)加强电针镇痛中的作用,采用高效液相一电化学检测法和放射免疫分析法,结合兔耳钾离子透入测痛,分别观察了L-THP在加强电针镇痛时免脑脊液中DA及其代谢产物DOPAC和HVA以及cAMP含量的变化。  
        
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    • 1989(Z1): 163-164.
      摘要:To date it is generally accepted that D2 receptor regulates the release andmetabolism of dopamine (DA) in negative feed-back way, and D1 receptor iscoupled to adenylate cyclase in a stimulatory way, To study the roles of D2and D1 subtype DA receptors in the potentiation of electroacupuncture (EA)analgesia by 1-tetrahydropalmatine (1-THP), the changes of contents of DA,DOPAC, HVA as well as cAMP in CSF were observed when analgesic effectof EA was potentiated by 1-THP.  
        
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    • 吴钢, 姜建伟, 吴根诚, 曹小定
      1989(Z1): 164-165.
      摘要:我们以前的工作表明左旋四氢巴马汀(L-tetrahydropalmatine,L-THP)与电针在镇痛上存在着协同作用。已知L-THP具有中枢多巴胺(dopaming、DA)受体的阻断功能。本工作在兔耳钾离子透入测痛模型上,于双侧侧脑室微量注射DA受体广谱激动剂DA和APO(epomorphine,去水吗啡)以及D_2受体选择性激动剂LY171555,观察中枢DA受体激动后,L-THP和电针镇痛作用的变化情况,了解中枢DA受体在L-THP与电针镇痛协同中的可能作用。  
        
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    • 1989(Z1)
      摘要:Our former work showed that there was a synergism of analgesia between1-tetrahydropalmatine (1-THP) and electroacupuncture (EA). Recently, it hasbeen verified that 1-THP is a new chemical type of central dopamine (DA) re-ceptor antagonist. To study the role of central dopaminergic system in thesynergism between 1-THP and EA analgesia, the effects of icv DA agonists on1-THP-induced analgesia and EA analgesia were investigated by using the po-tassium iontophoretic dolorimetry in rabbits.  
        
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    • 安定及其拮抗剂对电针镇痛的影响

      吴刚, 张菁, 崔毓桂, 姜建伟, 吴根诚, 曹小定
      1989(Z1)
      摘要:安定常被临床用于针刺麻醉术前和复合用药,但安定究竟是有利于还是不利于针刺镇痛,人们的看法不同。本实验在家兔耳部钾离子测痛模型上,观察不同剂量的安定及其特异性的拮抗剂RO15,1788(简写为RO)对针刺镇痛的影响。 1.小剂量安定对电针镇痛的影响静脉注射安定0.25mm/kg(n=16),60分钟内痛阈无明显改变。电针时给予该剂量的安定时,电针10分钟和20分钟时痛阈变化值为-0.01±0.04mA和0.08±0.06mA(X±SE,n=16),与电针加生理盐水组(0.4±0.16mA和0.54±0.14mA,n=16)相比明显偏低(P<0.05和P<0.01),表明电针镇痛被减弱。  
        
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    • 1989(Z1): 167-168.
      摘要:Diazepam was often used as an adjuvant drug prior to and during acupun-cture anethesia in clinics; however, there was a divergence of opinion uponthe effect of diazepam on acupuncture analgesia. The present study was toinvestgate the effects of various doses of diazepam as well as RO 15, 1788(RO),a selective benzodiazepine receptor antagonist, on electroacupuncture (EA)analgesia by using potassium iontophoretic dolorimetry in rabbits.  
        
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    • 5.7-双羟色胺对大鼠电针镇痛与中枢P物质含量的影响

      崔仁麟, 马春红, 赵飞跃, 田宇瑛, 蔡虹, 朱丽霞
      1989(Z1)
      摘要:一组大鼠脑池注入5.7-双羟色胺(5.7-DHT)100微克/20微升,9天后进行电针(30分)镇痛实验。另一组同样处理不给电针。第三组脑池注入溶剂与第一组同时电针。三个组在如上处理后均取脑干,腰髓进行P物质(SP)测定。结果溶剂组电针镇痛个体出现率(62.5%)与痛阈升高(131.2%)均与正常大鼠无异。5.7-DHT脑池注入的大鼠其电针作用被翻转(痛阈降低18%)此组脑干与腰髓SP含量均低于其它二组。此实验表明,正常情况下电针激活5-HT能下行性抑制,减少SP在脑干以下的传递性释放。5.7-DHT处理降低或消除此下行抑制,加速脑干和脊髓SP的传递性释放,同时翻转电针镇痛作用。  
        
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    • 1989(Z1): 168-169.
      摘要:The 5,7-dihydroxytryptamine (5,7-DHT, 100μg/20μl) was injected intoMagna Cisterna of the first group (5,7-DHT plus EA group) of rats, and the  
        
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    • 苏树伊, 郭淑琪, 卢运洋, 韩冠钰
      1989(Z1): 169-170.
      摘要:二羟基苯丝氨酸(DOPS)是去甲肾上腺素(NE)的直接前体,注入脑内后可使NE含量升高而不影响多巴胺(DA)含量,本工作应用DOPS研究中枢NE在针刺镇痛中的作用,并用5种受体阻断剂和激动剂在受体水平进行初步分析。 1.脑内注射(icv)不同剂量的DOPS1小时后脑内NE含量而增加针效随剂量而降低。 2.icv DOPS 200μg后1小时和2小时,脑内NE含量显著增加针效显著减弱,注射后5小时,NE含量回降,针效回升,接近对照水平。  
        
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    • 1989(Z1): 170-171.
      摘要:DOPS, the direct precursor of norepinephrine(NE), was used in this studyto (valuate the role played by NE of the brain in acupuncture analgesia.1. At the doses of 25, 50, 100, 200μg, one hour after applied by ivt,DOPS increased EN contents of brain and decreased the analgesic effect of EA.2. One and 2 hours after the ivt 200μg of DOPS, the analgesic effect ofEA was lowered with a respective increase in NE content. Five hours afterthe DOPS injection, the NE content came down and the analgesic effect of EAwent up, approaching the original levels.  
        
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    • r-氨基丁酸与针刺镇痛

      唐毓环, 潘玉贞, 刘国君, 王绍
      1989(Z1): 171-172.
      摘要:本室以往的一系列实验表明,丘脑上部的缰核不仅与痛觉和针刺镇痛密切相关,而且它是作为由边缘前脑至脑干以至脊髓的下行通路的各个神经结构之间的机能联系已经分别阐明,而且其中某些环节所涉及的神经递质也已清楚。已有文献报道,中枢神经系统中广泛存在的抑制性递质r-氨基丁酸(GABA)是参与边缘前脑抑制缰核活动的神经递质之一,但在针刺镇痛过程中,有关缰核中GABA含量变化的研究尚未见报道。本工作的目的在于了解针刺镇痛与缰核内GABA含量的关系。  
        
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    • GABA AND ACUPUNCTURE ANALGESIAGABA AND ACUPUNCTURE ANALGESIA

      1989(Z1)
      摘要:Abstract From a series of experiments Being done by these departments itis identifyed that halenula is not only closely concerned in the pain sensationand acupuncture analgesia, but also is the axis of the descending inhibitorypathway, from the limbic forebrain to the brain stem, which takes part in theaction of the antinociceptive information, including the acupuncture analgesia.In general, the activity of habenular nucleus is inhibited by the signals comingfrom the structures of limbic forebrain. What is the neurotransmitter mediated  
        
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    • 中枢乙酰胆硷在针刺镇痛中的作用

      艾民康, 关新民, 王才源, 茹立强
      1989(Z1): 172-173.
      摘要:十余年来针刺镇痛原理研究室以多学科密切配合,亦即应用临床与基础,形态与机能以及静态测定与动态分析相结合的方法,从不同角度对乙酰胆碱在针刺镇痛中的作用进行探讨,研究证明: 1.针刺能够提高机体的抗痛能力: 实验先后用不同型号的针麻仪,取不同的“穴位”,用不同的电针条件,通过不同的测痛方法(如辐射热、电、机械刺激以引起诉痛、嘶叫、甩尾、痛敏神经元放电等为痛指标)。均证明针刺有镇痛作用,能提高人和实验动物的抗痛能力。  
        
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    • 1989(Z1): 173-176.
      摘要:Acctylcholine (ACh) is the neuro transmitter which carliest emerges no matter in development of species or in evolution of individual. In some lower animalwhole sensory afferent nerve is cholinedergic, in advanced animals part ofnociceptive sensory neuroanatomic pathways is corresponding to ascending reti-cular exciting system. So it is possible that ACh is considered as one of impo-rtant neurotransmitters relating to acupuncture analgesia.  
        
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    • 外周ACh在针刺镇痛中的作用

      关新民, 艾民康, 王才源, 茹立强
      1989(Z1): 176-177.
      摘要:中枢ACh参与针刺镇痛已被证明。为了探明外周ACh是否参与针刺镇痛和针刺信息的传入,我们进行了一些实验性研究。结果发现: (一)组织化学观察发现:“穴位”处真皮内神经网,特别是皮下游离神经末梢和小动脉周围神经及神经小支呈AChE阳性反应,已知支配汗腺的神经和运动终板处也呈酶阳性反应。电针镇痛时上述结构的酶活性均增强。  
        
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    • 1989(Z1): 177-179.
      摘要:It has been demonstrated that central Acetylcholine (ACh) plays a role inacupuncture analgesia. In order to study whether peripheral ACh involves inacupuncture analgesia and input of acupuncture information, some experimentswere performed. The results were as follows:1. Observation of histochemistry showed that at acupoints the nerve net-works in the corium, especially the free nerve endings and the nerves aroundarterioles as well as small branchs of nerves in subcutaneous tissue, were AChE  
        
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    • 电针对脊髓背角内ACh代谢的影响

      施静, 艾民康, 关新民
      1989(Z1): 179-180.
      摘要:脊髓背角是感觉传入的重要中继站,为了探明脊髓背角内ACh在针刺镇痛中的作用,本文将从代谢的角度以动态变化的观点就针刺镇痛时ACh含量,和ACh合成酶及降解酶的活性等三个环节上进行综合研究。实验用SD纯种成年健康大白鼠72只随机分成两大组,每组中又分电针组和对照组,第一大组,测ACh含量和ACh的合成酶——胆碱乙酰化酶(ChAC),第二大组测ACh的降解酶——胆碱酯酶(ChE)。若将电针诱导10、20、30分钟时痛阈进行相关分析发现镇痛效应与电针强度呈直线正相关。(相关系数r=0.959P<0.05)  
        
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    • 1989(Z1): 180-181.
      摘要:Dorsal horn of spinal cord is an important relay of primary afferent. Inorder to investigate the effect of ACh in spinal cord on electroacupunctureanalgesia, the ACh contant,ChAC and AChE activity were measured. 72 rats wereused in this experiment and separated into two groups, A and B. Eachgroup was subdivided into electroacupuncture group and control group. TheACh content and ChAC activity in dorsal horn of animal group A; andAChE activity in those of group B were investigated. After electroacupun-cture induction for 10, 20, 30 minutes, it was found that the effectiveness ofacupuncture analgesia direct relation to intensity of electroacupuncture(relative  
        
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    • 张育文, 张娜娜, 钱晖, 刘晓春, 关新民
      1989(Z1): 181-182.
      摘要:本文将以生化的方法研究电针和切断后根后脊神经节和脊髓后角内AChE活性的变化,旨在探讨外周乙酰胆碱(ACh)与针感一级传入的关系;结果表明: 一、脊神经节内含有ACh。二、皮下注射新斯的明可使脊神经节内ACh含量升高皮下注射新斯的明125μg/kg,30分钟后,大鼠的痛阈未见明显变化,但脊神经节内的ACh含量却明显升高,与未给药的对照组相比,差异非常显著(P<0.001),表明,当用胆碱酯酶抑制剂抑制外周胆碱酯酶时,  
        
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    • 1989(Z1): 182-183.
      摘要:The present exneriment war carried out for the observations on changes ofACh content and AChE activity in spinal ganglia after dorsal rhiztomy andelectroacupuncture by means of physiological and biochemical methods andaimed at investigations into relationship between peripheral and acupunctureinformation transmitted through primary afferent. The results indicate:1. It was proved that ACh exists in spinal ganglia.The average value of ACh content measured bioassaily is 0.424±0.109ngper mg of humid tissue. The data is normal distribution.  
        
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    • 熊进军, 李和, 刘胜洪, 王庆堂
      1989(Z1): 183-184.
      摘要:He—Ne激光照射(简称光针)大鼠“足三里”穴位后,痛阈明显升高(P<0.001)。用PAP法观察了光针作用后大鼠腰段脊髓后角P物质(SP)和脑啡肽(ENK)免疫样反应产物的强度变化,并进行了定性和定量(相对光密度)分析。实验组与对照组相比,SP-LI产物明显增强(0.005  
        
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    • 1989(Z1)
      摘要:48 Wistar rats(190--250g) were used in this study.The pain threshold was very signifiantly hghier after lesar stimulation(LSA) than before LSA (P<0.001). Subslamce P like immunorcaction(SP-LI)was significantly enhanced (P<0.001) and enkephalin (ENK-LI) markedlydiminished (P<0.002) in the rat spinal cord of laser group than control group.Under transmissional electron microscope, the special dendroaxonic synapsewere found, the dendrite containi clusters of vesicles in a relatively lucentcytoplasm, but lacks a clearly defines ribosomes or endoplasmic reticulum. Thedouble labeling showed, we believe, direct contact between the ENK-LI contai-ning presynaptic dendrite and the SP-LI containing axonal terminal.  
        
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    • 涂宗苹, 张自东, 朱梓香
      1989(Z1)
      摘要:本文观察隔内TRH受体在镇痛和电针(EA)镇痛中的作用。58只S.D大鼠于双侧隔区埋置导管供微量注射,注射速度1微升/2分钟。EA用2~15赫、2伏电脉冲刺激双侧“足三里”、“三阴交”穴10分钟。用辐射热-甩尾法测痛,每5分测一次,共测50分钟。结果如下: 1.单侧隔内注入TRH(n=12),其痛阈均比对照组(n=12)明显增加(P<0.001~P<0.05)、100%并持续40分钟。 2.预先注入纳洛酮(NAL),3分钟后于同部位注入TRH(n=11),痛阈仍显著增加,与NAL加生理盐水(N.S)组(n=11)相应时间的痛阈比较,差异均有显著性;而NAL加TRH与单纯TRH组相比均无统计学意义。  
        
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    • 1989(Z1): 185-186.
      摘要:This article was to study how TRH receptors in the septal nuclei work inthe analgesic effect and EA analgesia.58 S.D rats were implanted with stainless steel guide tubes into the bilat- eral septal nuclei to provide microinjection, injecting speed 1μl/ 2min. "Zusanli"and "Sanyinjiao" were stimulated bilaterally for ten min, EA parameters were2--15Hz, 2v electric pulses. Using radiant heat teil flick method at 5minintervals for 50min, pain threshold (tail flick latency, TFL) was measured asnociceptive index. The results were as follows:  
        
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    • 张自东, 涂宗苹, 朱梓香
      1989(Z1)
      摘要:本实验试图探索TRH抗针刺镇痛(EA)作用是否与脑内cAMP有关。 42只体重180~250克S.D雌性大鼠,分为正常(n=8)、EA(n=8)、脑室注射(icv)生理盐水(N.S、n=5)、icv TRH(10μg/20μl)(n=5)、icv N.S.加EA(n=8)及icv TRH加EA(n=8)共六组。EA均刺激双侧“足三里”和“三阴交”用辐射热甩尾法测痛。所有动物于EA或注药后30分钟断头取脑,分离脑区,用放射免疫方法测定垂体、隔区、尾核、下丘脑和丘脑五个脑区的cAMP含量。其结果是:  
        
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    • 1989(Z1): 187-188.
      摘要:It has been shown that analgesic effect caused by EA is related to many neurotransmitters or cAMP in the brain. The aim of this study was to investi-gate whether the analgesic effect of EA antagonized by i.c.v. TRH was relatedto cerebral cAMP.42 female albino rats weighing 180--250g were used in the experiments.They were divided into six groups at random. Bilateral "Zusanli" and "San-yinjiao" of all rats received EA were stimulated. After stimulation with onestrength for 10min, it was stopped and pain threshold (PT) was determinedimmediately by radiant heat-induced tail-flick method. All rats were killed bydecapitation and their brain were quickly removed at 30 min after EA or i.c.v.  
        
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    • 活体伏安法研究大鼠下丘脑去甲肾上腺素浓度与针刺关系

      潘建粹, 夏冰, 邓家祺
      1989(Z1)
      摘要:本实验应用脑内活体动态测定NE含量的碳丝微电极先进技术,进一步研究电针过程中HVM内NE的动态变化。本实验应用200-250g wistar大鼠,大鼠用定位仪固定后,将碳丝微电极插入大鼠的HVM及其附近部位,观察电针前、后NE含量的动态变化。一、在下丘脑腹内侧核及其邻近脑区可记录到LSV,共有三个峰出现,分为峰Ⅰ(vitc)Ⅱ(NE)、Ⅲ(代谢产物)。实验时峰值每隔5’测定一次,待峰值稳定后,测定6—7次,取其均值为电针前峰值,然后用G6805电针治疗仪的疏密波在双侧“环跳”穴进行电针诱导,其强度由0.5格开始,每5’增加0.5格,增加到1.5格后继续诱导15’,取其峰值的均数为电针后峰值。  
        
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    • 1989(Z1): 189-190.
      摘要:The present work is to determine the concentration of norepinephrine (NE) in rat hypothalamus by linear sweep voltammetry (LSV) using the ultramicrocarbon fiber electrode for study of acupuncture analgesia mechanism.Experiments were performed on 220--250g wistar albino rats. After therat was put on the operation table inserting the fiber electrod into the HVMand other neighbouring nuclei of the rat's brain, then we determined directlythe concentration of NE, in order to observe the change of norepinephrineconcentration before and after electroacupuncture. Vivo is determined every 5minutes for keeping the fiber electrode stablize.  
        
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    • 电针对实验性心绞痛时心泵功能的影响

      吴培林, 孟竞璧, 付卫星, 宋利明
      1989(Z1): 190-191.
      摘要:本实验采用犬35只,经戊巴比妥钠腹腔麻醉,人工呼吸,开胸暴露心脏,行颈动脉—蠕动泵供血给冠脉前降支,造成心肌缺血15分钟时电针双侧内关穴,由北航57—6型针麻仪供给疏密波(1-20Hz),强度为负载5伏,电针20分钟,停电留针30分钟,第二次电针20分,  
        
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    • 1989(Z1): 191-192.
      摘要:This experiment was performed on 35 dogs anesthetized with pentobarbitalsodiom in abdominal cavity. These dogs were intabated and maintained respi-ration. The heart was exposed through a left lateral throacotomy, throughperistatic pump, blood in carotis was transported to left anterior descendingcoronary (LAD), experimental myocardial ischemia modal was set up epicardiumelcctrocardiogram of 12 points left ventricular pressure(LVP) and mean arterialpressure (MAP) were recerded with 8-channel polygraph. Cardiac output wastecorded with MF-27 electromegnetic blood flowmeter. The experimental  
        
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    • 面针镇痛及其作用机制探讨

      唐仲良, 张瑞生, 吴震荣, 张时宜, 李丽卿
      1989(Z1)
      摘要:一、当人体某一部分发生病变时,往往会在相应的区域或穴位处出现压痛点,电阻降低或伴有形态和色泽变化。根据这些反应,可以对躯体或内脏疾病的定位起辅助诊断作用。应用电阻测定仪,对121个病人合计242病例进行面部腧穴低电阻的测定工作,结果表明:符合率为60.3%(即低电阻反应与息者的主诉和临床诊断相一致的)。在面部24个腧穴中,出现反应点的有17个穴位。二、结合面针的临床实践,应用家犬进行面针镇痛的模拟实验,以探讨面针的作用途径。  
        
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    • 1989(Z1): 193-194.
      摘要:I. While the pathological changes occurred at the certain part of the bodysurface, there were tender points, low-resistance points and colour changes on relative area of body surface. According to these responses, we could diagnosethe pathological changes of soma and internal organs. The present work wasto measure the low-resistance points of face by an instrument of electrical resi-stance in 121 patients with a total number of 242 cases. Responses appearedmainly in 17 out of 24 face-points, but there were no responses on "guli","shou", "gu", "xi" and "qi". The physiological responses occurred occasionallyin other face-acupoints, such as "zigong", "pangguang", "pi", "dan" "zu" and"wei".  
        
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    • 关于深刺“阳关”穴镇痛作用的实验研究

      梁勋厂, 张静, 张娜娜, 关新民
      1989(Z1): 194-195.
      摘要:对深刺督脉一“阳关”穴的镇痛作用及安全度进行了一些动物研究,希望能对临床工作提供一些有用的实验参考资料。实验用成年SD纯种大白鼠166只,雌雄不拘,随机分组,测痛用WQ—9E测痛仪,将刺激电极刺入大白鼠尾中部皮下,无关电极置于脚掌,用方波脉冲刺激电流引起动物嘶叫时的毫安(mA)数表示痛阈。进针取穴方法:取相当于腰4—5椎脊突间隙垂直刺入至椎体后退针少许时针可垂直自立。  
        
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    • 1989(Z1): 195-196.
      摘要:166 SD rats weighing from 150 to 250g, used in this experiment were ran-domly divided into groups. Electroacupuncture needles were connected to aDM-A acupuncture instrument of fixed quantities. By using a WQ-9E dolorime-ter, St electrode was inserted into the subcutis of the middle of a rat's tailand non-electrode into the sole of a rat. The PT at the moment of rat's sere-aming was measured as milliaperes with interruptive increasing impulse current.  
        
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    • 几种针灸疗法的镇痛作用及其与5-HT相关性的比较研究

      马自佳
      1989(Z1)
      摘要:本实验采用兽医学上常用的百会穴,用钾离子透入测痛,在大鼠身上进行了电针,手捻针,微波针,6毫瓦He-Ne激光针和15毫瓦He—Ne激光针镇痛效应的研究,证实上述八种针灸疗法都能产生明显的镇痛作用,其中以电针的作用最好,依次为微波针,手捻针,6毫瓦He—Ne激光针,15毫瓦He—Ne激光针。并且不同针刺产生镇痛的后效应不尽相同,不同针刺,尤其是激光针刺存在一个最佳刺激量问题,在临床上适用针刺镇痛时应对针刺方法和刺激量所选择。  
        
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    • 1989(Z1): 196-197.
      摘要:For the purpose of further studies the analgestic effects of different kinds of acupuncture, the experiment have been done by using varied acupuncturestimulating "Baihui" acupoint of rats. The results showed that the acupuncturesof varied kinds may produce analgestic effects, but the effects are differentamong these kinds of acupuncture. The electro-acupuncture has the best effect,  
        
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    • 激光穴位照射对动物痛阈的影响及有关机理的研究

      于船, 张克家, 陆钢, 王清兰
      1989(Z1)
      摘要:激光技术引用于兽医针灸的研究,尚属一个新的领域。我们于1977年底至1985年6月间,利用了近8年的时间,对新西兰家兔和比利时杂交兔(463只)、杂种狗(51只)、内江杂猪(15只)、内蒙古细毛羊(73只)、内蒙古白山羊(68只)和美国SD品种大白鼠(50只)共720只,不同科属动物,根据实验要求分成若干组,进行激光穴位照射的痛阈测定。测痛方法系采用钾离子透入法,用WQ—9D型痛阈测量仪测痛。每个数据取测痛三次的平均值。穴位选用山根、抢风、百会、后三里、寸子和交巢穴等,按传统方法和电子穴位测定仪定位。He—Ne激光功率密度为28.3mW/cm2(2mW)、84.gmW/cm2(2mW)、84.gmW/cm2(6mW)、283mW/cm2(6mW)、283mW/cm2(20mW),除大白鼠照射10分钟外,其余动物均为15分钟。CO_2激光功率密度为639.6W/  
        
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    • 1989(Z1)
      摘要:In order to investigate the changes of the animal pain threshold and theaction of endorphin, serotonin, etc. in the process of irradiating animal acu-points with laser, from 1977--1985, the animals of different kinds--50 rats, 51dogs, 462 rabbits, 15 pigs, 68 goats and 73 sheep were divided in many experi-mental groups and control groups. The experimental groups were irradiatedwith laser in different acupoints (Shangen, Qiangfeng, Baihui, Housanli,Cunziand Jiaochao), or first irradiated and then injected some drugs (D-phenylala-nine, D-leucine etc.), or irradiated and, at the same time, injected some drugs  
        
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    • 针刺激活脑内镇痛机能系统而实现针刺镇痛

      曹小定
      1989(Z1): 199-200.
      摘要:自1964年底以来,我们坚持基础与临床结合,进行神经生理、神经药理、神经形态和神经生化等多学科综合研究,结果表明针刺穴位的传入冲动沿着痛、温觉传导途径(脊髓腹外侧索)上行到脑,激活了脑内镇痛机能系统,引起边缘系统的某些结构及以内阿片肽为主的递质系统的积极活动,通过激活下行抑制系统而实现针刺镇痛。主要内容如下:  
        
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    • 1989(Z1): 200-202.
      摘要:Ever since 1964, we have carried out experimental and clinical researchesto study the mechanism of acupuncture analgesia(AA) using multidisciplinarytechniques of neurophysiology, neuropharmacology, neuromorphology and neuro-biochemistry. It was found that afferent impulses arising from the acupuncturepoints travel along the neuropathway of the pain and temperature sensation(ventrolateral funiculi) of the spinal cord, reach the brain and activate thepain modulating system including some brain areas of limbic system to bringabout neurobumoral interaction among endogenous opioid peptides and differentneurotransmitters to activate the descending inhibitory system thus resulting inanalgesia. The main results are as follows.  
        
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    • 略论针麻临床研究的思路与方法

      王翘楚
      1989(Z1): 203-204.
      摘要:针刺麻醉临床研究成功,是近一百年来中国传统医药的一大突破。由于针麻研究成果的应用和推广,不仅推动了针灸医学的发展,而且为现代医学关于“痛”的研究开辟了新的途径。然而,针麻究竟怎样研究成功?从科学技术史和思维方法上究竟有些什么可供我们以启示和借鉴,是一个值得探讨的问题。  
        
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    • 1989(Z1): 204-206.
      摘要:The success of the clinical study of acupuncture anesthesia is a breackthro-ugh of traditional Chinese medicine in recent century. Owing to the applicationand popularization of the achievement of acupuncture anesthesia, the acupun-cture as a subject was developed, and a new way to the study of pain wasalso explored. How the research of acupuncture anesthesia can be succeededand what we can learn from the scientific and technologic history and thinkingmethod is a problem should be probed furtherly.  
        
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    • 针药结合在垂体瘤摘除术中的应用

      王梦敏, 马君志, 宋进生
      1989(Z1)
      摘要:1980年至1985年在针药复合麻醉下施术69例,男性39例,女性30例。最大年龄62岁,最小年龄19岁。右额叶U形切口,或额部冠状切口。手术时间最长240分钟,最短73分钟。取穴与刺激方法: 第一组:颧髎、耳垂、率谷透含厌,下关。第二组:颧髎、赞竹透鱼腰、合谷,外关。第三组;颧髎,赞竹透鱼腰,金门,太冲。  
        
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    • 1989(Z1)
      摘要:Clinical DataOperations were performed on 69 patients under acupuncture anesthesiacombining with drugs from 1980 to 1985, among them, males 39, females 30.The oldest patient was 62 years old, the youngest 19, most cases were middleaged.The "U" shape incision on righ frontal part, or coronary shape incision onfrontal part was used. Duration of operations: The longest was 240 minutes,the shortest 73 minutes.  
        
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    • 针麻在颌面外科手术中的应用——附65例报告

      铁朝云, 杨美芬
      1989(Z1)
      摘要:本文总结应用针刺麻醉于部分面颌外科手术,收到较为满意的临床效果。根据中医经络腧穴理论结合手术的不同部位和要求,我们确定了以下选穴原则:一、上颌区手术主要选择下肢穴位;二、下颌区手术主要选择上肢穴位;三、选用具有明显镇痛作用具有较强整体调节作用的穴位,实践中逐渐筛选出以下七个主六,上颌区选用合谷、丰隆、太冲、公孙,除合谷外,各穴均在下肢膝下,符合中医“上病下取”的治疗原则。根据经络走向,丰隆、太冲、公孙所属经脉均分布于上颌区,亦即此三穴与上颌区有着密切联系。下颌区选用合谷、内关透外关、后溪,此四穴所属经脉分布于下颌区,故诸穴配伍对下颌区有较强的通经活络,镇痛作用。不论上颌区或下颌区手术,选用合谷均有良好效果。  
        
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    • 1989(Z1): 208-209.
      摘要:We applied acupuncture anesthesia to 65 maxillofacial surgeries during 1979to 1988. This method was proven satisfactouy by our clinical studyGeneral data of 65 cases, 42 were male and 23 female. Our patients' ageranged from 17 to 78 years, The duration of operations were from 30 to 660 minutes.Points selection. If disorder located mainly in maxillary area the pointsof "Heku", "Fenglong", "Taichong" and "Gongsun" were selected. When lesionwas determined in madioular avea, the points of "Heku","NeiGuan", "WaiGuan",and "Houxi" were employed. When operative field would involved both sidesof face, bilateral points were selected accordingly.  
        
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    • 针刺镇痛的临床观察

      王宗学
      1989(Z1): 209-210.
      摘要:一、用针刺麻醉的方法治疗疼痛性疾病 1.三叉神经痛:取穴:第Ⅰ支痛攒竹透鱼腰;第Ⅱ支痛巨髎透四白;第Ⅲ支痛下关,地仓透颏孔,第Ⅰ、Ⅱ、Ⅲ支疼均配合谷、外关。进针有针感后加电脉冲刺激,用连续波频率20赫兹留针30—60分钟。50例中疼痛消失者21例,显效者8例,减轻14例,无效7例,有效率86%。  
        
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    • 1989(Z1): 210-211.
      摘要:I. TREATING PAINFUL DISEASES WITH ACUPUNCTURE ANESTHESIA1) Trigeminal NeuralgiaZanzhu through Yuyao is used for the pain of the first branch; for the secondbranch pain, use Juliao through Sibai; for the third, Xiaguan, Dicang throughthe Jaw hole. Hegu and Waiguan can be uued coordinately for pains of thethree branches. Inserting needles, when patients get the sensation induced byacupuncture, adding electric pulse stimulation with continuous wave of 20 Hz,retaining needles for 30--60 minutes. Among 50 cases. the paia disappearedfor 21 cases; 8 cases obtained excellent result; 14 cases were relieved; noeffect for 7 cases. effective rate: 86%.  
        
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    • 2046例耳鼻喉科手术针麻临床总结

      周继福
      1989(Z1)
      摘要:我们于1970~1988年开展针刺麻醉,共作14种手术2064例,针麻效果优良1862例,优良率达90.2%。手术采取循经取穴方法,获得满意效果。在穴位上进针得气后,将电脉冲刺激仪(G—6805治疗仪)之输出接头分别连接于左右手穴位上之银针,诱导30~60分钟。刺激参数随手术不同而异。针麻剂量与麻醉效果有密切关系。针麻效果,据本组统计,诱导时间在30~60分钟的针麻效果(特别是肌肉松驰)与镇痛作用较30分钟以内为优。  
        
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    • 1989(Z1): 212-213.
      摘要:For 18 years(1970--1988), 2046 cases of 25 kinds of ENT operations underacupuncture anesthesia have been done in our hospital. 90.2% of them havegot fine results and satisfying efficacy.The acupuncture points have got from and along the Meridian of humanbody.  
        
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    • 针刺麻醉下气管代喉术

      黄鹤年
      1989(Z1)
      摘要:本所近年来将针刺麻醉下全喉截除术的经验,应用于气管代喉术共五例,获得成功。气管代喉术主要应用于较晚期的喉癌,需作全喉截除术的患者,于切除喉体后保留会厌软骨,游离颈段气管,将其提到舌骨水平,使会厌与喉咽瘘口的粘膜缝合,重建斩喉,以代替已截除的喉,可获得术后发音的效果。  
        
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    • 1989(Z1): 213-214.
      摘要:5 cases of reconstruction of larynx under acupunture anesthesia are reported, In dealing with total laryngectomy on patients sufferred from rather advancedlaryngeal carcinoma, the laryngologists have been confronted with a problemof method in reconstructing a larynx in order to restore the funcion of phonation.The author has used the epiglottis which was sutured to the cervical tracheaand laryngopharyngeal mucosa to form a neolarynx.  
        
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    • 三种刺激方法在623例针麻甲状腺手术中的应用

      张仁惠
      1989(Z1): 214-215.
      摘要:在统一观察项目与评级标准下,本文将623例甲状腺手术随机应用于电针、电极板、手法捻针等三种刺激方法,比较了三组之间镇痛效果,并同时对不同穴位与不同手术方式进行了探讨。 623例中,男性186例;女性437例;年龄13岁~76岁;病种:甲状腺瘤387例,甲状腺囊肿64例、结节性甲状腺肿99例、甲状腺机能亢进61例、甲状腺癌12例。  
        
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    • 1989(Z1): 215-216.
      摘要:In 623 cases of thyroid operation under acupuncture anesthesia three kindsof stimulation, electroacupuncture, plate-electrode and hand-manipulated method,were randomly applied. The analgesic effect was compared among the threemethods. And, a inquiry was made into the effect among different selectionsof points and among different operative patterns. In all cases the uniformobserving items and criteria were used.  
        
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    • 针麻甲状腺手术辅助药物作用的临床观察

      李丽卿, 蒋录云, 朱美丽, 陈德尊, 储维忠
      1989(Z1): 216-217.
      摘要:本文观察了单纯性甲状腺瘤切除术80例,其中男16例,女64例,单侧腺瘤73例、双侧腺瘤7例。分为两组;加用辅助药物组45例、不用辅助药物组35例,分别施行针麻手术。两组病员一般情况基本相同,针麻方法:取双侧合谷、间使;面针:首面透心、甲麻穴。辅助用药组于术前20分钟肌注杜冷丁50mg或安定10mg,诱导时间为20~30分钟。按全国统一标准进行评级:分为优、良、差、失败四级。  
        
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    • 1989(Z1): 217-218.
      摘要:In this paper, 80 cases were observed on whom simple thyroid resection wasperformed. Of them, 16 were male cases and 64 female cases. 73 casues suff-ered on unilateral side and 7 on bilateral sides. They were divided into twogroups: 45 cases in one group with adjuvant and 35 cases in another withoutadjuvant. Each case was operated under acupuncture anesthesia. The generalconditions of both groups are basically the same. Acupuncture anesthesia wasmade on bilateral Hegu(LI4) and Jianshi(P5), by way of joined puncture fromface points Shoumian to Xinqu and on Jiama. Either 50mg of dolantin or 10  
        
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    • 音乐电针麻醉用于甲状腺手术40例观察

      刘守智, 葛长义, 东治广
      1989(Z1)
      摘要:我院从1987年10月以来,对40例甲状腺手术采用音乐电针麻醉,效果满意,其成功率100%Ⅰ、Ⅱ级率95%。本组病例中甲状腺机能亢进9例,结节性甲状腺肿7例,甲状腺腺瘤24例。其中男性2例,女性38例,年龄最小28岁,最大66岁,以30~50岁居多。术式均采用甲状腺(单侧或双侧)大部切除术。  
        
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    • 1989(Z1): 219-220.
      摘要:Our hospital, since October 1987, has achieved satisfied results in 40 casesof thyroid operation under musical electro acupuncture anaesthesia. Of allthese perations, the successive-rate reaches as highly as 100% and excellent andgood rate was 95%. It is now summarized as follows:  
        
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    • 吴月凤, 章强, 张怀珍, 刘秀吟
      1989(Z1)
      摘要:一例甲亢合并心房纤颤的患者在针麻下做了甲状腺双侧次全切除。现将病历介绍如下:患者高秀云女50岁住院号147524。1987年9月住院、诊断:双侧弥漫性毒性甲状腺肿伴有甲状腺机能亢进,合并心房纤颤。经治疗、症状好转,心电图仍示心房纤颤,心功能Ⅱ-Ⅲ级。于1987年11月10日针麻下行甲亢手术。术前30分钟肌注杜冷丁50毫克,针麻选穴:双耳神门、交感。连续电脉冲刺激,频率3600~5000次/分,电流强度以病人最大耐受为限。辅助用药:芬太尼0.05毫克加氟哌啶醇2.5毫克,静脉共用2次间隔65分钟;  
        
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    • 1989(Z1): 221-222.
      摘要:Bilateral subtotal thyroidectomy under acupuncture anaesthesia has beensuccessfully performed on one patient with artrial febrillation-complicatedhyperthyroid in our department. A 50 years old female (Gao Xiuyun, No.147524) was admitted in September, 1987. The diagnostic result showed a di-ffuse toxic qoiter with hyperthyroid, complidated by artrial fribrillation. Afterreceiving certain period of treatment, she felt better then before. However,electrocardiogram still indicated artrial fribrillation, the cardiac function testalso revealed a grade of Ⅱ or Ⅲ. She thus underwent the bilateral subtotalthyroidectomy under acupuncture anaesthesia on November 10, 1987. First,  
        
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    • 针刺复合麻醉行颈椎手术100例分析

      张德琛, 张淑平, 王志国, 夏舒萌, 于卫江
      1989(Z1)
      摘要:我院用针刺麻醉加颈浅神经封闭行颈椎前入路手术100例。其中男75例,女25例,年龄最小15岁,最大69岁。手术包括颈椎骨折半脱位,颈椎间盘等手术,并取髂骨植骨。手术时间最短80分钟,最长310分钟,平均156分钟。辅助用药分为两组;一组是针麻加局麻和芬太尼,另一组是针麻加0.125%布比卡因和芬太尼。从两组效果来看针麻加0.125%布比卡因封闭效果好而且辅助用药少,全身反应轻。穴位选择为双侧合谷、内关、电压为0.3~0.5mv,刺激频率为120~180次/分,针麻仪为G6805型,诱导时间15~30分钟。颈浅神经封闭用药配制:0.75%布比卡因5毫升加0.9%氯化钠盐水25毫升使成为0.125%的浓度分别注入双侧颈浅神经各15毫升。  
        
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    • 1989(Z1): 223-224.
      摘要:100 case-operations on cervical vertebrae were done by means of acupunctureanaesthesia combined with cervicalis plexus block or with local anaesthesia inclu-ding the operation of cervical vertebra broken subluxation, tuberculosis of ce-vicales, intervetebrates as well as ilium orafting/multiplication. The minimumoperating time was 80 min., the maximum 310 min. The mean time was 156 min.Among them the male patients were 75 cases, female 25, and the youngest was15 year old, the oldest 69.  
        
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    • 合并心血管疾患的颈椎后路针麻手术50例临床观察

      赵秀珍, 胡淑兰, 王素琳, 蒋建渝, 王宽
      1989(Z1)
      摘要:我院自1978年以来,开展了针麻下行颈椎后路手术。其中有50例合并心血管疾患病人,也在针刺麻醉下顺利完成手术,并取得了满意的效果,Ⅰ、Ⅱ级率达80%以上,现小结分析如下。颈椎后路手术多采用俯卧位,且出血量较多,增加了麻醉循环和呼吸管理的困难。本组50例病人年龄为19岁~77岁。合并有高血压及心血管疾病。采用针刺麻醉行颈椎后路手  
        
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    • 1989(Z1): 224-225.
      摘要:We have acupuncture anesthesia for operations of cervical spine dy poste- rlor approach sine 1978. There were 50 cases with cardiovascular disease.The effects were well with 80% of first and second degree.Operations of cervical spine by posterior approach are done in prone po-sition. This position affects respiratory and circulatory system. And this kindof operations bleed more so it is disadvantageous to respiration and circulationcontrol. The patients are unconsciousness under general anesthesia, thereforethey can not point out their spinal cord or nerves root be injured or not duringthe surgery.  
        
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    • 手法针麻肺切除术的临床体会

      陈德尊
      1989(Z1): 225-226.
      摘要:本文作者开展针麻肺切除术的临床研究已近30年,在不断地实践和提高积累了一定的体会。着重指出应用手法针麻、循经取穴的方法,针麻效果为较佳,并显示出采用手法和循经取穴针麻的优越性。在手法针麻中根据“针入贵速,既入徐进”的要求,提出针刺进针操作时应一捻一播迅速透入皮肤,待针透入皮肤后,皮下略停片刻,然后按不同刺法的要求进至一定的深度,但均必须首先使之得气,如未得气,应作催气的方法,以求得气。本文认为针刺的“得气”产生,每因被针的人与操作者的不同,所表现的反应现象也是多种多样,所以在针麻中针灸医生的固定与否,将影响病人的“得气状态”的好坏。因为“得气状态”的好坏,与针麻的效果有密切的关系。  
        
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    • 1989(Z1): 226-227.
      摘要:The author summarized the experience of lobectomy with acupuncture ane-sthesia for the past thirty years. The effects would be better if the acupu-nture followed the rule of acupointing through the meridians. The importanceof the way of manipulating the needling was stressed, it is worth to make quickinsertion and then forward slowly. the manipulation should be accomplished bytwist and thrust, a short hold-on after the initial needling, then further the  
        
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    • 针麻肺切除手术期间肺阻抗通气的变化

      张敏
      1989(Z1)
      摘要:应用肺阻抗通气图对6例针麻肺切除手术患者按手术前,针刺诱导(或针药诱导)切皮、切肌、开胸、处理肺组织、关胸、缝肌、缝皮等9个手术步骤进行观察记录胸腔液体指数(TFI)。每分钟呼吸(R)变动阻抗(ΔZ)、肺容积变量(ΔV)等指标。从直接测得的指标来看,本组针麻诱导后与诱导前相比除每分钟呼吸频率有显著差异(t=3.26、P<0.05)其余均无显著差异(P>0.05)。而用异氟醚吸入全麻病员与麻醉前相比,TFI有明显变化(P∧  
        
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    • 1989(Z1): 227-228.
      摘要:Six cases of lung resection under acupuncture anesthesia were taken moni-torined during the following procedures: Pre-operation, insert needles, indu-ction, incision of skin and muscles, open-chest, mangement of lung tissue,close chest, sutures of muscles and skin.  
        
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    • 针麻肺切除术时脑电图监测及技术特点

      李德芳
      1989(Z1)
      摘要:我院自1984年以来,以针刺麻醉施行肺叶切除术时用脑电图进行监测探索其脑功能的变化过程,在此期间我们用药物麻醉的病例也监测了脑电图以此作为对照。监测对象:脑电监测32例,其中针麻20例,药麻12例,年龄15~70岁,以40岁肺癌患者占多数,男24例,女8例,手术以肺叶切除为主。  
        
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    • 1989(Z1): 228-230.
      摘要:Since 1984, in our hospital, we use the EEG monitoring in lung lobectomy with acupuncture anesthesia in order to explore the functional alteration of thebrain. Patients with anesthetic anesthesia are also monitered with EEG forcontrol.Total number of patients for EEG monitoring was 32, among them patientswith acupuncture anesthesia 20 and with anesthetic anesthesia 12, the age of thepatients ranged from 15-70 years old, were 24 males and 8 females. Majorityin this series (32 cases) are 40 years old and suffered from carcinoma of lung.Most of the operations are lung lobectomy.  
        
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    • 针麻肺切除术57例失败病例的分析

      刘圣灵, 裘德懋
      1989(Z1)
      摘要:本院自1960年6月至1987年3月共施行针麻肺切除术1250例,其中有57例针麻手术未成功,失败率为4.56%,现将57例失败原因分析如下: 诱导时就不愿做针麻有3例;切皮、切肌时疼痛剧烈有11例;开胸后四肢乱动不配合4例;处理肺门血管:纵膈扑动利害或咳嗽剧烈妨碍手术进行19例;处理肺门血管破裂而引起的手术意外改全麻者10例;癌症转移、术中需做冰冻切片,手术难度大2例;气管内有痰、清醒插管有困难1例;超量用药7例。  
        
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    • 1989(Z1): 230-231.
      摘要:In this article 1250 cases of acupuncture anaesthesia for pulmoctomy in ourhospital since June 1960 to March 1987 were analysed, among them 57 caseswere failured, the rate of failure 4.56%, the causes of failured as following:3 cases unwilling for acupuncture anaesthesia during introduction period, 11 caseshad severe pains at the procedure of cutting skin and muscle layers, 4 casescan't cooserated because of four limbs acting in disorder after open chest cavity,19 cases hinder the operation going further because of mediastinum flutter heavy  
        
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    • 手法针麻肺切除不用药不插管病人11例术后随访

      周红
      1989(Z1)
      摘要:本文分析本院自1961~1983年期间139例手法针麻肺切除术用药不插管病人中11例且符合下列三个条件;(1)呼吸<35次/分,(2)血压、脉搏的变化较诱导前基数分别:收缩压<30mmHg,脉搏<30次/分,(3)仅有微痛者的病例通过随访分析如下:  
        
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    • 1989(Z1): 231-232.
      摘要:139 cases of don't using adjunct drug with hand manual acupuncture anest- hesis for lobectomy since 1961-1983 in our hospital were analysed, among them11 cases (1964-1966) don't using adjunct drug and bronchi intubate during ope-ration, all of these cases (a) the breathe<35times/Min. (b) the change of bloodpressure and pulse compared before acupuncture introduce the systolic pressure<30mmHG, pulse<30times/Min. (c) only have slight pain, were given follo-wing-visit and analysed in this article.  
        
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    • 保持最佳得气和药物提高针效在针麻胃手术中的应用

      陈永荣, 陈沛, 陆鹤玲, 陈德尊, 李丽卿, 蒋录云
      1989(Z1): 232-233.
      摘要:我们认为提高针麻成功率的途径是:一、辨证施治辨证施针,这不仅可以掌握针麻适应症,更重要的是可以针对不同情况,采取不同手法获得和保持最佳得气,提高针刺效应。同时术中运用气功样浑而慢的腹式呼吸,使针麻胃切除术成功率提高。二、采用与针麻效应有明确协同作用的芬太尼、氟哌啶为术中辅助用药,弥补针刺效应之不足,用量极小避免药物付作用。  
        
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    • 1989(Z1): 233-235.
      摘要:We believe that there are two approches to the rise of success rate ofacupuncture anesthesia: 1. we must offer diagnosis and treatment and selectdifferent acupoints based on an overall analysis of symptoms and signs. Thiswill enable us not only to know well indications of acupuncture anesthesia, butto apply different needling manipulations in line with different conditions, soas to keep optimal needling sensation and improve acupuncture effect. At thesame time, deep and slow abdominal breath used in qigong practice was taken,  
        
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    • 针麻切脾术103例临床观察

      胡丽梅
      1989(Z1)
      摘要:笔者参加了103例晚期血吸虫病肝硬化门脉高压患者在针麻下行脾切除术的临床研究,疗效满意,成功率:94.2%、优良率:75.7%,现总结如下: 103例中,男性73例,女性30例,年龄最大66岁,最小17岁,本组除一例脾肿大Ⅰ级外,其余均在Ⅱ级以上,其中5例上消化道出血内科保守治疗无效行急症手术。35例有不同程度粘连,51例术前轻度腹水,2例中度腹水,21例合并各种不同程度夹杂症。针麻效果按一九七五年全国统一针麻评级标准,Ⅰ级38例,Ⅱ级40例,Ⅲ级19例,Ⅳ级(失败)6例。三组取穴的总成功率94.2%,优良率:75.7%。  
        
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    • 1989(Z1): 235-236.
      摘要:This article deals with the clinical research on splenecotomy performedunder acupuncture anesthesia in 103 cases of portal hypertension in the late stage of schistosomial hepatocirrhosis.The successful rate was 94.20%, excellent rate was 75.70%; and among 103cases, 73 were male, 30 female, of the age from 17 to 66 years old; the dura-tion of the operations was generally two hours, the shortest was one hour andthe longest five hours; all the cases had quick recovery after the operations,neither complications nor any case of death were odserved.  
        
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    • 幼儿针麻腹股沟斜疝手术临床应用

      张哲元, 周德华, 李建中, 李应义, 朱嘉环
      1989(Z1)
      摘要:应用针麻行幼儿斜疝手术23例,年龄为1~7岁,按针麻穴位处方不同分为两组,①针麻Ⅰ组12例,取六:三阴交、内麻点、切口旁针,术前药为东茛菪硷0.01mg/kg。②针麻Ⅱ组11例,取穴:足三里、神门透交感、切口旁针、术前药为氯丙嗪、异丙嗪各1.5mg/kg及东莨菪硷0.01mg/kg。选择7例局麻作为对照组,术前药同针麻Ⅱ组。均在基础麻醉下进行手术。针麻Ⅰ组2例、Ⅱ组4例、局麻组2例按Shoudice’s法修补加强腹股沟管后壁,其余均行高位结扎术。针麻效果按三级评定法,幼儿评级指标与成人不尽相同,在基础麻醉下,肢体扭动和挣脱反应是疼痛的明显标志,轻痛时患儿肢体移动,有时哭闹,而无皱眉等动作,明显疼痛时,肢体挣脱固定带,身体扭动,影响手术进行,术中允许使用0.5%普鲁卡因3~5ml,超过5ml为失败。本文针麻成功率为95.6%;局麻组以0.5%普鲁卡因25ml以下为Ⅰ级,超过者为Ⅱ级,Ⅰ级占71.4%。  
        
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    • 1989(Z1)
      摘要:This series includes 23 cases of inguinal hernia operated under acupunctureanesthesia. The success rate came up to 95.6%. The points prescribed weredivided into two groups: the first group was Sanyinjiao, internal anesthesiapoint, Wushu penetrating towards Weidao, Daju penetrating towards Qugu;The second group was Zusanli, Shenmen penetrating towards Sympathy, Wushupenetrating towards Weidao, Daju penetrating towards Qugu; 7 cases under localanesthesia were contrast group. The B. P., P. R., E. C. G., respiratory pattern  
        
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    • 针麻疝修补术21例临床观察

      李丽卿, 陈德尊, 蒋录云, 陈宣桃, 陈永荣, 陈沛
      1989(Z1): 238-239.
      摘要:为了提高针麻疝修补术的成功率及优良率,按照全国针麻疝修补术的临床研究协作组的拟定方法,结合我们历年来的针麻疝修补术的临床经验,我们重点注意;辨证施针,采用远近配穴法和定期改变电针波型:辨证用药,把握着小剂量芬太尼、氟哌啶辅助用药的时机。结合外科手术操作的改进,在针麻临床中观察了21例疝修补手术,其中男20例,女1例。年龄范围:14岁以下2例,15—50岁7例,51—79岁12例。手术的成功率提高到90.4%,优良率提高到71.4%。  
        
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    • 1989(Z1): 239-240.
      摘要:In order to raise the successful rate and good rate of herniorrhaphy underacupuncture anesthesia, we put stress on the application of following principlesaccording to the method worked out by the National Collaborating Group ofClinical Research of Herniorrhaphy under Acupuncture Anesthesia and by combi-ning our own clinical experience obtained in performing herniorrhaphy underacupuncture anesthesia over a number of years: use of needles based on diffe-rentiation of symptoms and signs and use of medication based on differentiationof symptoms and signs. In the former, a combination of distal and local acu-points is selected and wave form of electroacupuncture is changed regularly; in  
        
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    • 针麻腹式全子宫切除术临床规律研究

      屈晓馨
      1989(Z1)
      摘要:自1978年以来,由西安、湖南、重庆、北京、上海五个地区七个单位组成的宫切协作组共完成了1267例。进行了穴位优选,筛选出头针…中焦透下焦,体针…改良次髎穴和五枢透维道,组成穴位处方,经过验证,优良率为80.47%。用HRP法进行了穴位与内脏相关形态学研究,提示本组穴位处方对子宫切除手术具有相对特异性。在研究影响针麻效果的基础上,总结了术前予测方法,提示了植物神经相对稳定和肾阳虚患者针麻效果较好,为病例选择提供了科学依据,探索合适的刺激参数,改进手术操作,制定了针麻下施行腹式全子  
        
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    • 1989(Z1): 240-241.
      摘要:Since 1978 the Hysterectomy Collaboration Group consisted of seven unitsin Xi'an, Hunan, Chongqing, Beijing, Shanghai had completed 1267 cases in total. After preferential selection of acupuncture points used, cephalic needli-ng-Zhongjiao through Xiajiao and somatic acupuncture points modified ciliao andwushu through weidao are screened in the constitution of a point-recipe, whichhas been canfirmed in practice that the rate of excellence has reached 80.47%.Morphological examination with HRP method of correlation between acupancturepoints and viscera has suggested points in this recipe are relatively specific forhysterectomy. Based on studies of factors influencing acupuncturing effects  
        
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    • 从中医理论探讨针麻下腹式全子宫切除术病机见解

      郑玉英
      1989(Z1): 241-242.
      摘要:作者从针麻下腹式全子宫切除术261例中根据病人术中反应,脉舌变化,来探讨体内脏腑气机活动。针麻下腹式全子宫切除术病机分析,是以中医整体观念为指导,手术虽在局部进行,但全过程是金刃所伤,伤津夺液,损气耗血,气机紊乱的过程。反映出正、邪两方面相争。稳妥过渡三个阶段,是针麻成败的关键。  
        
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    • 1989(Z1)
      摘要:The author has discussed the activities of Zangfu (viscera) and functionof essential energy on reactions in 261 abdominal pan-hysterectomized casesduring operation and their variations in pulse and tongue as well.In analysing methanism of abdominal pan-hysterectomy under acupunctureanesthesia, it is essential to be guided with the concept of whole in ChineseTraditional Medicine. Although the operation is done locally, during the oper-ative course it consists of scalpel trauma, loss of body fluid, injury of essentialenergy and blood, disturbance of functional activities of essential energy. It  
        
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    • 唇电针麻醉应用于妇产科手术1268例

      李荣基
      1989(Z1)
      摘要:我院自1976年至1987年共采用唇针电麻应用于妇产科手术1,268例。其手术种类八种、优良率98%。本组最小18岁、最大46岁、手术种类有输卵管结扎、卵巢瘤切除,腹膜内剖腹产,腹膜外部腹产、子宫卒中、子宫破裂行子宫全切除,子宫破裂行子宫修补,宫外孕行单侧输卵管切除,恶性葡萄胎行子宫全切除。手术时间最短18分钟、最长3小时30分钟。  
        
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    • 1989(Z1)
      摘要:The kinds of operation: tubal ligation, oophorectomy, cesarean sectioninside the peritoneum, cesarean section outside the peritoneum, uterus apoplexy,metrorrhexis using hysterectomy left cervix, metrorrhexis recovering the uterus,entra-uterine gestation using one-side hysterosalpingectomy, malignant hydatidi-form mold using whole hysterectomy, 98 percent of the patients get well.  
        
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    • 耳针加光针麻醉在腹腔镜技术上的应用

      徐正仪, 胡象莲, 樊祥松, 钟惠芳
      1989(Z1)
      摘要:本文介绍一种耳针加光针的麻醉方法,使腹腔镜技术能更安全有效地应用于临床。耳针与光针的方法及取穴依据:1988年4月1日至7月15日本院在耳针与光针麻醉下进行腹腔镜操作。耳针采用神门透子宫、脑点透肺,组成一对刺激电极。电针诱导15分钟。在术前再用氨氖激光照射脊中六30分钟。将本组34例与同期之局麻34例,静脉麻醉24例,硬膜外麻醉24例共82例作对照。  
        
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    • 1989(Z1): 244-245.
      摘要:The beneficial effects of auricular-plus laser-acupuncture anesthetic methodto yield better security and more effective results when applied to laparoscopyin clinics were introduced in this article.The method of auricular-plus laser-acupuncture and the selection of theacupuncture points were judged as follows: From April 1 to July 15, 1988,laparoscopy was manipulated under the auricular-and laser-acupuncture anesthe-sia in our institute. In auricular acupuncture, one pair of stimulating electrode  
        
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    • 针麻三刃钉内固定术的临床观察

      李丽卿, 朱美丽, 蒋录云
      1989(Z1): 245-246.
      摘要:针麻施行三刃钉内固定术的临床研究表明,采用神经干穴位和同神经节段取穴比其它取穴的效果较好,能使针麻的优良率有明显提高。为了探索针麻三刃钉内固定术选用神经根加体针或耳针、面针选穴的针麻效果是否优于单纯神经根选穴针麻效果进行临床观察。本组观察了针麻下施行三刃钉内固定术224例,其中单纯神经根选穴组113例;男40例、女73例。神经根选穴加体计或耳针、面针穴组111例;男37例、女74例。两组病例随机分组,手术  
        
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    • 1989(Z1): 246-247.
      摘要:The clinical study of internal immobilization of three-flanged nail underacupuncture anesthesia has shown that the effects obtained by selecting acupo-ints controlled by the corresponding nerve trunk and neural segment are betterthan those obtained by selecting other acupoints, leading to a marked rise ofexcellent rate of acupuncture anesthesia. In order to investigate whether theeffects of acupuncture anesthesia yielded by selecting acupoints dominated bythe corresponding nerve trunk together with body points and ear or face pointsare superior to those. yielded by only selecting acupoints dominated by thecorresponding nerve trunk, a clinical observation has been made. In this paper,  
        
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    • 王梦敏, 马君志
      1989(Z1): 247-248.
      摘要:息者男性24岁,以右上肢外伤后四年,活动障碍收住院。入院查血压120/70毫米汞柱,心率70次/分,心电图报告窦性心动过缓53次/分。胸透未见异常,血尿常规检查正常。拟择期第五次手术,作右臂丛神经探查及代肱二头肌紧缩术。由于对各种麻醉药,术前药、抗生素、皮试均过敏。会诊认为是多元性迟发型过敏。过敏原不详。故拟针麻下施术,不用术前药和辅助药及抗生素等,不输液。选穴:极泉、扶突(患侧)二穴,用北航57—6电脉冲仪,连续波,频率1200次/分。诱导一小时,强度逐渐加大。  
        
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    • 1989(Z1): 248-249.
      摘要:A 24-year-old male patient whose right upper extremity had been injuredfour years before was hospitalized because of diskinesia. Routine preoperativeexaminations were all normal. Now, a right brachial plexus nerve exploratoryand replaced biceps brachii constructive operation was prepared to performafter the later fourth operation.  
        
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    • 针麻效果综合预报的研究

      王友良, 王立民
      1989(Z1)
      摘要:为进一步提高与推广应用针刺麻醉,探讨其适应症和临床规律性,1985年11月~1986年7月我们应用多项指标对针麻效果术前预报开展临床研究。资料来源:1978年10月~1978年12月底完成的562例(资料不全者除外)临床资料。病种为:颅脑(前开颅)手术、斜视矫正术,肺切除术、胃大部切除术、子宫切除术、阑尾切除术、四肢骨科手术。应用各种手术切口的基础痛阈、基础耐痛阈、基础触觉阈、基础两点分辨阈、内关穴触觉阈,外关穴两点分辨阈,以及上列各指标针刺穴位15分钟后的变化值,还应用脉率、脉搏容积波的静卧值及针刺15分钟后变化值,同时记录某些心理因素指标及年龄、性别等。全部研究过程中预报与临床工作采用双盲法。预报均使用同型仪器,相同参数及操作。  
        
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    • 1989(Z1): 250-251.
      摘要:In order to popularize the acupuncture anesthesia and go further into theindication for acupuncture anesthesia and clinical regularity from November in1985 to July in 1986, 562 opperations of 7 kinds were performed under acupun-cture anesthesia by computer. The types of the operation were: craniotomy,strabomy, lung resection, subtotal gastrectomy, hysterectomy, Appendectomy,and the operation on the extremeties. The following parameters were selected:pain threshold and pain tolerance threshold, threshold of two-point discrimina-tion and threshold of tactile sensation, finger plethysmograin, heart rate andthe change of the above parameters 15 minutes after needling. And were recordedsex, age, psychological indices. The clinical condition under which the investi-gation was carried out was basically stable.  
        
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    • 针刺麻醉独特的针刺后效应

      杨蓁, 李传琪, 叶(王厉)君, 项立敏
      1989(Z1)
      摘要:本文观察130例针麻和药物麻醉术后切口痛反应(切口旁肌电图、血压、脉率等变化)和胃肠功能(排气时间、肠鸣音、肠电图、胃电图等变化),发现针麻时,连续运针所产生的针刺后效应,能参与术后镇痛,有效地降低术后疼痛反应。并可减轻因手术或药物引起的胃肠功能紊乱,促进术后胃肠运动的恢复。此乃针麻不同于药物麻醉的独特之处,现简述如下:  
        
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    • 1989(Z1): 252-253.
      摘要:In this report 130 cases of postoperative indices were investigated whichoperated with acupuncture anesthesia(AA) and drug anesthesia, also includedreaction of postoperative incisional pain (the changes in EMG of rectus mu-scle B. P and pluse rate) and the function of G-I tract (the change in EIG,EGG, peristaltic sound of intestine and duration for initial breaking of windthrough anus). The post-acupuncture efficacy resulted fuom continuous appli-cation of acupuncture must have been interposing in the course of the posto-perative analgesia effect. It can alleviate postoperative pain and the disturbanceof G-I function caused by operation or medication, thus promote post-operativerecovery of G-I tract.  
        
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    • 针麻术中证的研究和应用

      罗庆道
      1989(Z1): 253-254.
      摘要:本文总结了针麻效果不好的50例患者,发现术中表现和反应出来的症状、脉象、象舌等都有一定的规律性,由于这些规律性的症状、脉象和舌象发生在手术之中,所以称为“术中证”。一、术中证辨证分型 1.心气虚症候和心血虚症候导致——心神不安。 2.脾气不升与胃气不降,脾胃功能失调导致——胃气上逆。 3.经络受阻,气血不通导致——气滞血瘀。  
        
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    • 1989(Z1): 254-255.
      摘要:The results of animal experiment show that the effects of acupunctureanaesthesia are excellent in 75% cholecystectomy and 80% subtotal gastrectomy.This paper studied 50 patients whose acupuncture anaesthesia effects werebad. The results show that their symptoms signs pulse conditions and picturesof the tongue during operation are regular.Ⅰ. The classification of symptoms during opeation 1. The syndrome of deficiency of heart-energy and heart-blood--irritabi-lity.  
        
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    • 顽固性头痛的针灸辨证治疗

      陈大中, 沈荣宝
      1989(Z1): 255-256.
      摘要:各类顽固性头痛,经年累月奔波于中西医药,结果疗效不显。我们认为如能做到符合针灸三大要领,对某些所谓“疑难杂症”,往往能起沉疴于陈艾微针。本人临症五十余年,对针灸治疗各种头痛,虽不敢说能针到病除,但累积了些菲薄经验。自知年事已高,虚度八十有零,愿在小沈同志的协助之下,把几十年针治头痛的资料整理如下: 例一,肝郁头痛:巅顶剧痛如裂,痛不欲生。取穴:行间针(-)、命门灸(-)、劳宫针(-)、公孙针(-),一次愈。例二,血虚头痛:偏左头痛九年多取穴:三阴交针(+)。足三里针(+)、内关针(+)、左风池、悬卢针(+-)针治五次全愈。  
        
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    • 1989(Z1)
      摘要:Being a complication of many other diseases, headache is not an indepen-dent disorder. Brought about by their main illnesses which might be totallyover due to suitable remedies, many cases of headache may become eternalregret. The sufferers, year in year out, shuttle back and forth betweenwestern medicine and the traditional Chinese medicine with very little efficacy.Cherishing a trace of hope, they resort to acupuncture treatment. We hold  
        
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    • 针刺配合穴位注射治疗痛症

      张勤
      1989(Z1)
      摘要:本文阐述了在临床实践中,采用针刺配合穴位注射治疗十种痛证,取得了较好的疗效。治疗十种痛证取穴:1.头痛,取百会、大椎和阳陵泉。2.颈痛,取风池、增生和大椎。3.背痛,取募穴、内关和气海。4.腰痛,取肾俞、腰阳关和秩边。5.胸痛,取背俞穴、外关、支沟和绝骨。6.腹痛,取背俞穴、足三里和条口。7.肩痛,取风池、肩髃和肩贞。8.膝痛,取血海、阳陵泉和合阳。9.肘痛,取曲池和阿氏穴。10.指、趾痛,取合谷、后溪、绝骨和照海。除上述穴位外,需参照临床症状辨证加减。针刺手法以虚补实泻、平补平泻为治则。穴  
        
      793
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    • 1989(Z1): 257-258.
      摘要:The treatment of 10 kinds of painful syndromes with acupuncture and pointinjection in clinics are introduced in this artical.Prescriptions for:1. Head-ache: Baihui, Dazhui and Yanglingquan2. Neck pain: Fengchi, Zengshen and Dazhui3. Back pain: Mu points, Neiguan and Qihai4. Lombago: Shenshu, Yaoyangguan and Zhibian  
        
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    • 大椎穴镇痛疗效观察

      吴家淑
      1989(Z1)
      摘要:笔者多年来采用大椎穴刺络拨罐,治疗头痛、牙痛、咽喉肿痛,目赤肿痛,收到较满意的效果,现小结如下。共观察门诊病例540例。头痛206例,牙痛204例。咽喉肿痛87例,目赤肿痛43例。取大椎穴,配用侠脊(大椎穴两旁各开5分处),常规消毒,用三棱针点刺1至2分深,再以大椎穴为中心拨罐10至15分钟,每日治疗一次,三日为一疗程。  
        
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    • 1989(Z1): 258-259.
      摘要:The author selected the method of acupuncturing Dazhui with cupping totreat headache, toothache, inflammation of the pharynx and larynx and conjun-ctivitis andswelling and pain of the eye for years. The results have proved satisfactory. The summary has been made as follows:From 1965 to 1984, there were 540 cases on observation, including 206with headacbe; 204 with toothache; 87 with inflammation of the pharynx andlarynx and 43 with conjunctivitis and swelling and pain of the eye. Dazhui ischosen combined with the points in either side of the spine (5 fens away fromDazhui). The peck needling is used with a three-edged needle in 1 to 2 fensdeep after the routine sterilization, than cupping on Dazhui for 10 to 15 min-utes. There is one time a day and 3 days as a course.  
        
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    • 激光针治疗痛症76例疗效观察

      胡光志
      1989(Z1)
      摘要:激光针即小功率激光穴位照射,对许多疾病有良好的疗效。作者应用激光针的镇痛作用,采用了mW He-Ne激光直接穴位照射和病灶照射,治疗有带状疱疹、三叉神经痛、口腔溃疡等引起的癌症76例,收到显著效果。本组痊愈61.8%,有效率93.4%。口腔溃疡、带状疱疹,激光对其镇痛效果较好。激光针无痛、无感染,儿童和老年体弱者尤宜。  
        
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    • 1989(Z1)
      摘要:"Laser Needle", low output laser irradiation analgesia is effective in thetherapy of pain. The author used 3mW He-Ne laser irradiation directly on theacupuncture point or on the painful area in a study of herpes zoster, trigeminalneuralgia, aphthous ulcer, and others with 93.4% effective and 61.8% cured.Laser needle has the advantage of no pain, no possibility of infection,and especially adequate to aged and children.  
        
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    • 弱电点穴治疗头痛127例小结

      晏明
      1989(Z1)
      摘要:1986年国际头痛讨论会提出:“消除头痛的最好办法是戒除止痛药”。用自制微型电子止痛器,以耳穴为主,配阿是穴,取点压与点放手法,治疗时间每次约5分钟,对血管性、神经性、感冒等所致多种头痛127例,即刻有效,头痛基本消失1小时以上者有114例占89.8%;其中54例自我对照,去痛片有效者27例占50.0%,有9例对去痛片过敏而不能用,弱电点穴有效者44例(包括上述9例)占79.6%,P<0.01;认为本疗法解痛时间低于去痛片者5例占9.2%,认为高于去痛片者41例占75.4%,P<0.001。头痛伴视物模糊者,均感视力随头部轻松而顿转清晰。3例治疗后轻微恶心、头晕,约10分钟后自愈,未见其它明显副反应。本疗法在3~10分钟后即解痛,明显快于去痛片(一般半小时后起效),  
        
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    • 1989(Z1)
      摘要:In 1986, The International Headache Conference pointed out: The bestmethod of relieving headache is give up analgesic. The author used a minitypeof electrical analgesia instrument made by oneselt to stimulate a certain pointson the ears and head, usually, continuous stimulation was alternated withintermittent stimulation about 5~10 minutes for one treatment. Out of 127cases with headache that contained vascular headache nervous headache andcold headache etc. 114 cases lost their subjective complaints of headache imme-diatly and over 1 hour (89.8%). Among the group, 54 cases had taken theanalgesic, 27 cases were effective for the analgesic (50.0%), 9 cases happendside-- reaction for the analgesic, and 44 cases that contained the above-menti-oned 9 cases were effective for the electrical stimulation (79.6%), P<0.01.  
        
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    • 耳穴压迫治疗经期偏头痛——附9例病例分析

      祝秀都, 俞瑾
      1989(Z1): 261-262.
      摘要:本文报道经期偏头痛患者9例,经耳穴压迫法治疗1—2疗程,9例患者病程2—10年,按经络辨证少阳头痛5例,取肝、胆、额、太阳耳穴,阳明头痛4例,取肝、脾、胃、额耳穴,再加配穴,经前3—4天开始敷贴直到经净为止,左右耳交替。第一疗程8例有  
        
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    • 1989(Z1)
      摘要:9 cases with severe cyclic migraine during menstruation for 2--10 yearswere treated by ear pressing therapy for 1--2 cycles. The treatment started.3--4 days before menstruation and ended to the menstruation. 2 groups of earpoints were used in the therapy according to the theory of channels.  
        
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    • 弱电点穴致颈肌抽动法治疗颈肩痛42例体会

      晏明
      1989(Z1)
      摘要:笔者用自制微型电子止痛器,发现新穴——“颈肩痛穴”,用点压及点放手法,致颈肌规律性抽动。治疗急性落枕5例、颈椎骨质增生10例、慢性颈肌劳损27例共计颈肩痛42例,每次治疗时间约10分钟,即刻有效,疼痛基本或明显缓解、颈肩活动明显改善2小时以上者39例占92.9%,未见明显副反应。本疗法以弱电脉冲代替毫针,属无损伤疗法,治疗时间短,疗效快而强,无明显副作用,病人易于接受。针刺该穴不引起颈肌抽动,惟用本法引起颈肌规律性抽动,起到加压泵作用,有利于加快患部血循环,消除颈肌的痉挛与炎性肿胀,而活血消肿止痛。并认为弱电点穴法将利于发现针刺法不能发现的一些新的特异性穴位。  
        
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    • 1989(Z1)
      摘要:Author used a minitype of electrical analgesia instrument made by oneselfto stimulate a new point "neck-shoulder pain point" that caused the jerking ofneck muscles. Usually, continous stimulation is alternated with intermittentstimulation about total of 5~10 minutes for one treatment. Out of 42 casesof acute and chronic neck-shoulder pain, a surprising number of 39 cases losttheir subjective complaints of pain and incited the neck and shoulder to rein-state functional normalization immediatly and over 2 hours (92.9%), almostno side effect. Because this therapy used electrical stimulation instead ofacupuncture, it's a non-injured therapy. It has the properties of quick effect,  
        
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    • 应用针刺穴位手法治疗胸内手术后疼痛的观察

      邹学超, 周红, 刘圣灵, 李德芳, 张敏
      1989(Z1): 263-264.
      摘要:28例胸内以肺切除术为主的病人术后疼痛进行针刺穴位治疗,按疼痛部位循经及同名经上下肢相配的原则取穴,用捻转与提插相结合的手法。强度以病员有酸胀感能耐受为度,持续运针15~20分钟,留针5分钟,然后起针。监测指标有止痛效果及针刺前后血压、脉搏、呼吸、指端阻抗血流图和胃电图对比、针刺手法操作前后结果表明:所有病例均有一定程度的镇痛效果,针刺后11例由甚痛转为较痛,和1例转为微痛;16例由较痛转为微痛,血压、脉搏,呼吸除3例变化达20毫米汞柱或20次/分左右外,多无变化或在10毫米汞柱或  
        
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    • 1989(Z1): 264-265.
      摘要:Twenty-eight patients who had undergong lung resection, were treated withacupuncture for postoperative traumatic pain. We selected the points of thechanncls that traverse the site of the pain or that related to the concernedviscera. The needle were manipulated persistently with lift-thrust and rotationthat offer the patient a maximal tolerable needle sensation of sorenessand distention for 15--20 minutes. The needles after keeping for another aminutes, were taken off. Analgestic effectiveness, blood pressure, pulserate, finger impedance rheogram (FIR) and gastric electromyogram (GEMG)wtere asked or monitored as their own self-control and the data acquired afteracupuncture manipulation and needles off had shown as follows:  
        
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    • 综合针刺法在胸外科手术后镇痛效果观察

      谈国平, 张敏, 刘洪全, 何敖
      1989(Z1)
      摘要:本组30例胸外科术后采用综合针刺法镇痛、先后应用温针、腕针、耳针、水针。以杜冷丁25毫克肌注作自身对照。用钾离子测痛和血液循环功能监护仪来考核镇痛效果和调整功能。实验结果:1.痛阈提高以腕针最为明显,耐痛阈提高出现递进、叠加镇痛效果。2.各种针刺法均比杜冷丁镇痛效果显著,P<0.01。3.针后脉率减慢,心肌收缩力加强、搏出量增加。  
        
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    • 1989(Z1): 265-266.
      摘要:Four kinds of acupuncture, heat-acupuncture, wrist-acupuncturepuncture and hydro-acupuncture, were used for 30 patients after thoracic surgery. Analgesic effect and regulatory effect on cardio-circulatory funetion of acupu-ncture were obversed.  
        
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    • 灵龟八法治疗胃痛110例

      张有全
      1989(Z1)
      摘要:笔者用灵龟八法治疗胃痛110例,效果较好,报道如下。选穴:灵龟八法开穴,加辨证配穴。治法:患者仰卧位,常规消毒穴位后,用28号2寸毫针,在患者穴位刺入1至1.5寸,捻转提插,得先后根据病人的耐受强度给予不同刺激量。留针30分钟,如针感消失再行捻转提插,疼痛未减轻者再延长留针时间,以自觉疼痛减轻或好转为度。每日针1至2次,6次为1疗程,停针1日,继续第二疗程。治疗结果:疼痛完全消失为全愈,计96例占87.3%;疼痛基本消失,仍留轻微疼痛为有效,计11例占10%;疼痛无改变为无效,计3例占2.7%;总有效率为97.3%。  
        
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    • 1989(Z1)
      摘要:110 cases of stomachache were treated by acupuncture with "Ling Gui BaFa" based on an overall analysis of sysptoms and signs; The methods of selecting points were based on "Ling Gui Ba Fa". Cured cases: 96 cases (87.3%). Marked improvement: 11 cases (10%),The total effective cases: 97.3%.  
        
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    • 针刺治疗泌尿系结石绞痛182例

      杨丁林
      1989(Z1)
      摘要:182例中,男性150例,女性32例。年龄最大73岁,最小19岁。病程最长4年,最短小时。绞痛均为泌尿系结石所致。泌尿系结石绞痛多为突然发作,有尿频、尿急、尿病、血尿。并有腰痛、腹痛、肾区叩击痛,疼痛性质多为持续性绞痛和阵发性绞痛,疼痛放射至会阴及两大腿内侧。部分有恶心、呕吐。B超和X线造影及平片均能发现结石光、声响或结石影。尿检可发现红细胞(+~++++)。尿蛋白阳性。  
        
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    • 1989(Z1): 267-268.
      摘要:Of the 182 cases, 150 were male and 32 female. The oldest patient was 73of age, the youngest 19. The longest course of the disease was 4 years, theshortest 1 hour. All colic was caused by urogenital calculus.  
        
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    • 针刺合谷三阴交穴为主治疗重症痛经32例

      詹闯
      1989(Z1)
      摘要:本文阐述了以合谷、三阴交穴为主,依据交经缪刺法治疗32例重症病经的临床体会。本组32例病人中,多为少腹剧痛难忍、大汗淋漓,不能正常工作,其中年龄最小的15岁、最大的42岁、平均24岁;病程最长的十余年、最短的仅一天。按中医辨证分型,寒湿凝滞型20例、气滞血瘀型12例。 1.选穴:根据交经缪刺法,取单侧合谷(左或右)与对侧三阴交(右或左)。寒湿凝滞型加灸关元,气滞血瘀型针刺气海。 2.手法:用提插捻转复式手法泻合谷、三阴交,留针20分钟。  
        
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    • 1989(Z1)
      摘要:Thirty-two patients with severe dysmenorrhea were treated mainly by acu-puncture of Hege (LI 4) and Sanyinjiao (Sp 6) with Contralateral InsertionMethod. Some clinical data are shown as follows: Thirty-two patients suffered from dysmenorrhea had symptoms of intolera-ble pain on low abdomen, profuse sweating, unable to persit in normal work.The age of these patient is 15-42 year old with an average of 24. The longestcourse of the disease is more than ten years and the shortest only one day.According to the TCM differentiation of symptoms and signs, 20 cases belongto obstrctive type due to cold and dampness, whilc 12 to the type of stagna-tion of Qi and blood  
        
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    • 腰椎骨质增生100例治疗观察

      裘雪亭
      1989(Z1)
      摘要:我科从1984—1988年,选择了100例腰椎骨质增生患者,均经x照片确诊,作治疗观察。男44例,女56例。最大年龄76岁;最小年龄40岁。100例中有坐骨神经痛31例。(男9例;女22例)3例假性椎间盘脱出。根据辨证论治,分作两型: 一、腰椎骨质增生,腰痛不能俯仰。常因抬重举物,挫伤扭着所引起。取人中、委中、大肠俞、次髎,命门。得气后,平补平泻,隔5—10分钟,行针一次,留针20分钟。或出针后用当归注射液在大肠俞,或肾俞,作穴位注射,每穴注入1毫升。二、腰椎骨质增生后,腰痛经久不愈,牵引左侧或右侧脾枢及腿弯等处疼痛。(坐骨神经痛)。  
        
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    • 1989(Z1)
      摘要:Our clinic have treated 100 patients for three years since 1985. Age rangedlfrom 76 to 40 years old. Among them, there are 31 patients with neuralgiasciatic and 3 patients with false disci intervertibrales out. Illustrations havedecided by x-ray. Curative effect: Among the 1OO cases, 32 cases were recovered and 63 caesewere better than before.  
        
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    • 肘膝关节疼痛186例的针刺止痛疗效观察

      詹军
      1989(Z1)
      摘要:肘膝关节疼痛为临床常见之症状。我们自1983年7月起至今,用缪刺法治疗肘膝关节疼痛186例,取得良好疗效,现报导如下。一、临床资料性别及年龄:186例中,男115例,女71例。年龄最小15岁,最大67岁。二、针刺方法: 取穴治疗方法:治疗时,选取疼痛肘膝关节,上取下、下取上(肘取膝,膝取肘)对侧对应部位的阿是穴或经穴。如右侧阴谷穴部位疼痛,选取左侧尺泽部位,左侧少海穴部位疼痛、取右侧膝部相应部位阿是穴。进针得气后留针片刻,嘱患者活动患肢关节,至疼痛消失为止。  
        
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    • 1989(Z1): 271-272.
      摘要:Among all the patients, 115 were male and 71 were female. The youngest was 15 years old. The oldest was 67 years old. There were 98 cases whichhappened injury (53%) There were 49 cases which happened by wind coldness,wetness (26%). There were 49 cases which happened by steoproliferation (21%).Ashi Point or Channel point on the contralateral appendage of morbid elbowjoint and knee joint were selected. If upperextremity pained lower extremityshould be selected.  
        
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    • 针刺后溪穴治疗急性腰扭伤

      陈兴元
      1989(Z1)
      摘要:治疗急性腰扭伤的方法有多种多样。本文小结了自1987年9月—1988年7月采用针刺后溪穴的方法治疗该病150例,其中男性99例,女性51例,平均年龄47岁,就诊时间均在伤后5天以内。对有急性腰扭伤病史,腰部疼痛,活动不利,检查见腰部活动受限,有明显固定压痛点的确诊为急性腰扭伤患者,两手后溪穴同时进针2时许,稍加捻转,患者往往感到腰部板紧即刻松懈,疼痛减缓,有时取效迅速,进针即愈,令人惊叹。同时结合抬腿摆手步行活动,二者结合,起到相互协助,相互促进,加速伤愈的作用,使不少抬着进来的病人经这种方法治疗后能自行走着出去。经治150例,取得全愈83例,好转67例的良好疗效。  
        
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    • 1989(Z1): 272-273.
      摘要:There are manifold therapies for the treatment of acute lummbar sprain.This paper presents that 150 cases of acute lumbar sprain have been treated with the theary of puncturing Houxi points from 1987 to 1988. Among thesepatients there were 99 cases of male and 51 cases of female. The averageage of them were 47 years old. They were all treated at the time withinfive days after wound. The patients who had the history of acute lumbarsprain, waist pain, difficulty to move about, and were found to be ill With therestrictions on lumbar exercise and marked and fixed tender spots, and weredetermined to be ill with acute lumbar sprian were punctured 2 inch in bothHouxi points with twisting and twirling the needles at the same time. The patientsoften felt that the stiff sense and pain in waist relaxed immediately. In somecases the effects were so wonderful that the patients were healed immediately.  
        
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    • 马属动物六个主要镇痛血针穴位及应用

      张新厚
      1989(Z1)
      摘要:兽医血针疗法具有简、便、效、廉等优点。自古以来,我国劳动人民就十分重视应用这一疗法。此法对马、骡闪伤所致肢体疼痛、跛行和寒伤脾、胃所致胃肠痉挛疼痛疗效尤为明显,常可单靠撒血而迅速治愈。据多年临证体验,认为三江、胸堂等六个血针穴位镇痛效果理想,而及时撤血、保障撤血量要够。又是提高疗效和愈病的关键。  
        
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    • 1989(Z1)
      摘要:From ancient times, Chinese working people have been paying much atte-ntion to application of veterinary acupuncture blood-letting therapy which issimple, convenient, efficient and cheap. It is especially efficient to use thismethod to treat pain in the limbs and lameness with sprain and, spasmodic ga-stroenteralgia resulted from cold stimulation in horses and mules, Usually,they can rapidly cure only with the acupuncture blood-letting.  
        
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    • 硬膜外腔阻滞对电针传入的影响

      梁炎基, 张仁惠
      1989(Z1): 274-275.
      摘要:在针刺麻醉行胃手术时,选用背部穴位的效果较好,而在针刺复合硬外小剂量麻醉时,取背部穴位的效果却不如选用肢体的穴位效果佳。这可能是由于硬膜外阻滞后,电针背部穴位的针感传入受阻之故。为证实此点,我们在模拟临床小剂量硬外麻的动物模型上,以大脑皮层体感诱发电位为指标,观察了硬膜外阻滞区内外诱发电位的变化。  
        
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    • 1989(Z1)
      摘要:It was found that in combined acupuncture-epidural anesthesia the clinicaleffect needling the Shu-points located the area of epidural blockage was not soeffective as that needling the extremity points located out of the block area.This might be result of the needling sensation originating from back having be-ing blocked partly after epidural blockage. This viewpoint was confirmed inthis study. In present study the effect of epidural blockage on cortical evokedpotentials in an animal model similar to the clinical condition was studied.  
        
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    • 针刺环中上穴治疗坐骨神经痛效果的实验研究

      郝长源, 毕福高, 毕巧莲, 胡亚伟
      1989(Z1)
      摘要:我们对该病47位患者进行针刺环中上穴和巨刺疗法治疗。在治疗过程中使用ZK—3型直接式阻抗仪进行了54次针刺前后患肢肌肉震颤率、肢体血流量及阻抗数值变化的实验对比研究。肌肉震颤率是取每一波形起点后0.4秒内的肌肉震颤次数。振幅大于0.5mm者有效。肢体血流量是以Kublcek公式计算。为了方便dz/dtmax及SET值均以mm为单位的测量值计算。  
        
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    • 1989(Z1): 276-277.
      摘要:We treated 47 cases of sciatica with the upper circular center acupoint andthe method of contrateral acupunceure. The myoseism rate, the quantity of blood flow and the impedance value ofsick leg of the patient before and after the treatment were determined and co-mpared for 54 times carefully. The myoseism rate is the times of myoseism within 0.4 minutes after thestart point of the graph. The amplitudd larger than 0.5mm is effective. Qu-antity of blood flow is calculated by the Kublcek formula.  
        
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    • 应用红外热像仪观察穴位针刺前后的温度变化初步报告

      辜祖谦, 陈卫民, 叶平, 周诗毅
      1989(Z1)
      摘要:人眶、承颏这一对中西结合穴在拔牙术中有良好的镇痛效果,就只用这一对穴可以进行全口任何部位的拔牙术。自1988年对13名自愿受试者(男7,女6,其年龄在21~54岁之间,均系医务人员及医学生),用红外热像仪检测此二穴位针刺前后的温度变化。 1.针尖所达点右侧眶下孔和左侧颏孔表面,其静止时温度与针后、诱导后及拔针后20~22分钟(下同)相比皆有显著差异。 2.对照点左侧眶下孔表面,其静止时温度与针后、诱导后温度相比有显著差异,但与拔针后相比则无显著差异。  
        
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    • 1989(Z1)
      摘要:It has been proved any teeth of all position can be extracted with the pairof Renkuang and Chenghai acupoints. 13 volunteers were accepted in this experiment, the following points onthe skin surface were dicided: ①Infraorbital foramen bilaterally; ②mentalforamen bilaterally; ③renzhong(Du 26)and chengjiang(Ren24). recording the figures of temperature in the following stages: original sta-tus; after needling (within 1.5'); after 20' from needles withdrew. The results showed: the highest one was 1.6℃ different from a pair ofsymmetrical points after acupuncture.  
        
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    • 多功能《经络导气治疗仪》临床镇痛效果分析报告

      王旦森, 何成奇, 李伯宁
      1989(Z1)
      摘要:应用《经络导气治疗仪》,治疗各种病因引起的具有疼痛症状的腰痛、腹痛、头痛、胸胁痛、肩臂痛等病症114例。治疗方法是按祖国医学经络理论进行辨证,确定病痛在何经,然后采取循经远道取穴将电极贴放在穴位上通电。每次20分钟,每日一次,三次为一疗程;如病情需要可每日二次,慢性痛证可10—15为一疗程。本组114例中显效31例占27.19%,好转73例占64.03%,无效10例占8.28%,总有效率91.22%。  
        
      773
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    • 1989(Z1): 279-280.
      摘要:114 cases of pain syndrome including lumbago, belly pain, headache, chest& hypochondric pain, and arm Shoulder pain were treated by San Tai Hospitalof TCM and our institute. In the light of the diagnosis of TCM, the involvedchannels are determined and the distant (5 Shu points) and local acupoints are used. The electric stimulation will last for 20 minutes, once a day, 3 timesmake a course. In chronic and serious cases, twice a day, 10-15 times make acourse.  
        
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    • 针麻甲状腺手术术前予测

      陈树德, 秦必光
      1989(Z1): 280-281.
      摘要:协作组应用中医辨证分型、经络感传、手法试针测痛、弹簧棒耐痛阈测定、钾离子透入痛阈测定,皮肤温度变化及血管容积波变化等方法,作为术前予测针麻甲状腺手术效果,结果如下。于术前3日内按照祖国医学辨证方法,分为虚证、实证及其它三型,共观察468例,其中虚证219例,实证236例,其它13例。针麻效果优良率分别为79.9%,75.4%,76.9%,P>0.01,各型之间,无明显差异;术前一日针刺、手术选用穴,观察经络感传现象,共观察517例,若针刺后感传循经到达手术区为敏感型,计13例。若感传能循径传导一段距离为稍  
        
      674
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    • 1989(Z1): 281-282.
      摘要:The Coordinating group had estimated the elinical effect of acupunctureanesthesia for thyroidectomy. The predicting work had been done by differentmeans, such as differentiating of symptomes and signs according to Chinese me-dical theories, observing the trasmission of needling sensation along the channels,measuring pain by manipulating the needles and pain threshold by spring sticks,and by infiltrating k+ into the body skin, testing the skin temperature andwaves of the blood vessels.  
        
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    • 针刺复合小剂量硬膜外麻醉胃大部切除效果观察

      秦必光
      1989(Z1)
      摘要:本文介绍四川省胃针麻协作组(由成都中医学院、四川省人民医院、华西医科大学附一院、三台县人民医院、绵竹县人民医院组成)探索提高针麻临床效果,克服“三关”的途径,在病人健康条件相似的胃十二指肠溃疡手术,按手术先后随机采用:1.针刺复合小剂量硬膜外麻醉(下称针硬组);2.小剂量硬膜外麻醉;(下称小硬组)、3.针麻等三组麻醉方法施行胃大部切除术共71例,其中男63例,女8例,平均年龄40.8岁;诊断为胃溃疡29例,十二指肠溃疡42例;实施Ⅱ式胃大部切除37例、Ⅰ式胃大部切除34例。麻醉方法:1.针硬组系在针麻基础上,再配合小剂量硬膜外麻醉(共25冽);2.小硬组系连续硬膜外腔阻滞,用1%利多卡因、0.15%地卡因混合液,首次量5毫升,达到切口疼痛完全消失,即开始手术,若病人诉痛则再追加上述局麻药3毫升直到疼痛消失(共24例);3.针麻组,穴位左右足三里,  
        
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    • 1989(Z1): 283-284.
      摘要:This paper introduced the clinical works of Sichuan Coordinating Group ofAcupnncture Anesthesia for raising the effect of acupuncture anesthesia andseeking for a way to overcome the "three important problems" of acupunctureanesthesia. All the patients were divided into three groups randomly for differentanesthesia methods. Group 1: Acupuncture combined with epidural anesthesia in small dosageof corcomitant drugs.  
        
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    • 电脑专家系统胃切除针麻效果术前预测

      秦必光, 张兰英, 王立民
      1989(Z1)
      摘要:王友良等对500多例针麻手术预测进行分析,给出了针麻临床效果术前预测公式,我们初步用该公式于临床胃大部切除手术59例进行预测,方法稳定可靠,建立一个统一的电脑诊断专家系统是可行的,本文较详细地叙述了临床应用方法与体会。一、方法:按照1978年全国针麻预测会议拟定的标准对59例胃切除针麻手术病员,于术前1—4天在环境较安静,室温20°—30℃规定的条件下,观察了脉搏容积波、脉率、右内关穴触觉阈、左内关两点区辨阈及K+测痛(痛阈、耐痛阈)。入室20—30分钟针前值。针刺右内关、右足三里后接G-6805型针麻仪,通电15分钟后再测上述指标变化值,同时记录年龄、性别及某些心理因素等,采用双育法进行(仪器、参数及操作均相同)。  
        
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    • 1989(Z1)
      摘要:After analysing the predicting records of the effects of acupuncture anes-thesia for 500 cases undergoing subtotal gastrectomy, Wang Youliang et al hadput forward a new formula to evaluate the clinical effects of acupunctureanesthesia. It was quite stable and reliable. This paper introduced the clinicaluse of this formula.  
        
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    • 督脉针麻施行760例肝胆胃肠手术效果的研究

      秦学礼, 董学诗, 林晓明, 曾国栋
      1989(Z1)
      摘要:一九七四年五月,我院与第四军医大学及郊东县人民医院协作,研究了督脉针刺麻醉法。先后施行腹部手术四十多种计2300余例,其中用于肝胆胃肠手术760例,按全国针麻效果评定标准,本组的成功率为98.28%,Ⅰ、Ⅱ级率占80.52%。本法的取穴原则是根据督脉是人体诸阳经脉的总汇并与数条经脉交会联于脏腑和现代医学中脊髓节段与皮肤及内脏的关系选穴,上腹部手术取神道或巨阙俞(奇穴,即位于督脉上),中、下腹部手术取至阳。进针部位达硬脊膜外腔附近,进针深度成人胸段3—5厘米,腰段2—4厘米,同时于腰骶部置一铅板作回路电极,进针深度的标志是接联针麻仪后,刺激量由小逐大,脊髓节段相应的平面可呈现有麻重感或漂浮感,并有轻微颤动。  
        
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    • 针麻行阑尾切除术20例临床观察

      孙频声, 李立志, 侍明宏
      1989(Z1)
      摘要:现将我院在针麻下行阑尾切除术20例,并随机20例以局麻为对照,进行临床观察:穴位处方:主穴:双侧足三里。配穴:双侧合谷穴。术前用药:术前30分钟肌注东茛菪碱0.3mg,唛啶50mg,氯丙唪、异丙嗪各25mg。  
        
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    • 1989(Z1)
      摘要:Twenty cases undergoing appendectomy with acupuncture anesthesia,com-pared to random sample of twenty cases with local infiltration were observed. The results were no significant differences between the group of theacupuncture anesthesia with main points Zhusanli and side points Hegu and thegroup of the local anesthesia with 0.5% novacaine infiltrated in the effects ofanalgesia. The successful rate of the antsthesia respectively was 90% and80%. However, in respects of the early gas passed, the reducing administrationof the analgetics and the rate of the wound infetion, the group of the acupun-cture anesthesia was statistically signifcant better than the controls, especiallyin septic appendicitis complicated with general septic periltonitis and septicshock, acupuncture made the blood pressure restore, the heart rate stabilize,  
        
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    • 夹脊穴用于女性腹式绝育术102例

      刘成信
      1989(Z1): 288-289.
      摘要:应用夹脊穴作女性腹式绝育术102例,取得较好效果。按神经节段分布而选择了胸11, 12与腰1夹脊穴、用毫针刺到第11、12胸脊神经,第1腰脊神经附近。捻针针感达手术野。按上电极通过脉冲仪刺激脊神经,可使该神经支配的范围内的痛阈提高。出现一个和神经于相一致的感觉迟钝区临床上麻醉镇痛效果显著增强。优良率91.2%,但探索提取输卵管时,少部分病人牵引痛较为明显,尚需进一步克服“镇痛不全”的问题。  
        
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    • 针刺“内麻点”麻醉应用于四肢骨科手术198例分析

      常庚申, 李金明
      1989(Z1)
      摘要:“内麻点”是止痛效果较好的新穴位,我院从1976年初开始将“内麻点”应用于骨科手术麻醉,开始时都有配穴,通过临床实践,从1978年4月开始单纯用“内麻点”麻醉施行骨科手术306例,取得了较好效果。现将其中资料完整的198例整理报告于下: 198例中,男性142例,女55例,l例记录不全,最大年龄72岁,最小年龄13岁,手术时间最长者300分钟,最短者10分钟。施术范围包括上肢的手腕部、前臂、肘和上臂,下肢的髋、股、膝、小腿和足踝部,总优良率为71.2%,成功率为90.9%。  
        
      710
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    • 1989(Z1)
      摘要:Neimanian-point is a newly-found acupoint with a good analgesic effect,306 orthopedic operations of extremities were performed under Neimadian-pointacupuncture anesthesia with good results. Of all the cases, 198 cases that hadcomplete clinical materials were selected and analysed in the paper. 142 caseswere male and 56 cases were female. The age of the patients ranged from 13to 72 years. In the series the longest time the operations lasted was 300  
        
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    • 53例骨科手术应用针麻体会

      姜宗弟
      1989(Z1): 290-291.
      摘要:我院1965年至1983年共作针刺麻醉1347例,骨科手术针麻53例,占针麻总数的3.9%,成功率为83%。包括上肢下肢骨折开放复位,脊柱结核病灶清除术,截肢等20余种。多数为青壮年、最大年龄87岁,重危休克病员6例。针麻方法有耳针、耳穴注射和体针三种。以耳针为主。根据脏象学说及经络学说取穴,诱导20—30分钟,切皮前常规静注杜冷丁50mg(成人)。麻醉结果、一级5例,二级22例,三级17例,四级9例。失效率17%。体会中摘出,针  
        
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    • 耳针耳压对胆囊炎胆石症止痛效果观察

      管遵信, 李惠芳, 朱志, 魏凡, 管钟明, 赵永祥, 华毅敏
      1989(Z1): 291-292.
      摘要:一、一般资料:本组病例都是通过B超式x线胆囊造形确诊的胆囊炎、胆石症患者,均具有疼痛症状。共270例其中男63人,女207人。男:女为1:3.3。11一20岁2人,21~30岁16人、31~40岁35人,41~50岁38人,50岁以上129人。病程在一年以内者94人,1~3年103人,4~10年54人,10年以上19人。单纯性胆囊炎26例,胆囊炎合并胆石症198例,单纯性结石40例,术后综合征6例。  
        
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    • 针刺对体表痛觉的影响—穴位特异性的初步研究

      沈龙媞, 沈克非
      1989(Z1): 292-293.
      摘要:为探索针刺镇痛效应,我们分别以中枢和命门为主穴观察电针刺激两组穴位对体表痛觉的影响,为进一步探索穴位特异性,提高针刺的镇痛效应,提供资料。实验对象为21名需作腹部全子宫及附体切除术一次广泛术以及附件切除术者,年龄在26—54岁之间,两组年龄、体质、病种与手术种类大致相符。方法用“一半方波电刺激法”,刺激强度以毫安计算。体表皮肤痛觉测定均以受试者主观感受的口述为标准,以刚感到疼痛时的电流强度作为痛阈;继续增强刺激到疼痛难以耐受的电流强度为耐痛阈。测痛部位在面部、胸部、右前臂、左下肢以及下腹部共取十个测痛点。测痛及进针人员固定。进针前测痛  
        
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    • 在针灸止痛过程中三针,三线理论与实践的意义

      张琼
      1989(Z1): 293-294.
      摘要:在1987年于北京举行的世界针联讨论会上我们已基本上发表了关于三针、三线、三水平与三阶段治疗的主要内容。 150名具有腰痛病人的治疗中我们应用这一方法。结果证明这一方法的应用大大的提高了针灸的疗效,表1。  
        
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    • 21例四肢骨科手术针刺麻醉疗效分析

      常庚申, 李金明
      1989(Z1)
      摘要:我院在针刺麻醉下施行四肢骨科手术21例。男性17例,女性4例,最大年龄60岁,最小年龄18岁。手术时间最长200分钟,最短18分钟。上肢手术6例,膝关节部位手术13例,足部手术2例,手术种类有单纯肌腱软组织手术,有截骨骨折内固定术,有截骨加肌腱移位术。总成功率为95.2%。选用全国四肢组,统一规定的穴位,上肢患侧天鼎、极泉穴,下肢患侧的环跳、冲门穴。  
        
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    • 1989(Z1)
      摘要:We performed 21 orthopedic operations of extremities under acupunctureanesthesia with good results. There were 7 cases male and four female cases.The age ranged from 18 to 60 years. These operations lasted 18—200 minutes.These are 6 operations on the upper extremities, 13 on knee joint and 2foot. The success rate is 95.2%.  
        
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