摘要:隔区指的是终板前方,前穿质上方,胼胝体下回下方的区域。此区有内侧隔核(Sm)和外側隔核(Sl)。大鼠隔区的主要核团包括Sm、Sl及斜角带核(td),td又以前联合平面分为以前的斜角带核垂直支(VDB)和其后向两侧延伸的斜角带核水平支(HDB)。在有些动物的隔区内,曾描述过多至16个独立的核。隔区有多方面的机能,与情绪反This review summarized some articles on the effect of the septal area in acupuncture analgesia. The data showed that the pain threshold of animal was increased when septal area was stimulated by electro-acupuncture, and that electrical stimulation of septal area had a marked inhibitory effect on the pain
摘要:我组曾报道脑室注入促甲状腺素释放激素(TRH)能对抗电针镇痛,其作用机理不清。隔核与脑室紧密相邻又是前脑边缘系统的重要结构,与其他边缘系统和脑区都有着密切的联系,它具有多种生理功能,许Experiments were performed on awake rats. The pain threshold (tail flick latency. TFL) was measured with radiant heat tail-flick methed. Microinjection of thyrotropin releasing hormone (TRH 2.5μg/1μl) into septal area can increase remarkably and last 40min, but the analgesic effect can not be reversed by the opioid receptor brocker Naloxone (NAL) into the septal area; injection 10μg of Morphine into unilateral septal nucleus, the pain threshold had no obvious change;
摘要:七十年代,烟台地区发表了针刺日月、期门治疗胆石症52例的报告,总排石率84.6%,此后临床上采用电针加服硫酸镁治疗胆管结石522例,总排石率78%。到八十年代初,生理学方面已做了大量的研究Twenty two rabbits were selected for the experiment and were divided into three groups. CT-HRP or CB-HRP was injected respectively into the ampulla wall (group 1) or acupoint area Riyuc (group 2) or Qimen (group 3). The results obtained are as follows: Group 1, The labelled cells appeared in the spinal ganglia from T_3 to T_(11) on the left side and T_2 to T_(10) on the right side, and a lot appeared in the nodose ganglion of the vagus nerve on both sides. The transganglionic labeled terminals were found in the region of the solitary nucleus on both sides. A lot of labelled
摘要:催产素(Oxytocin,OT)是在下丘脑室旁核和视上核内合成的一种垂体肽类激素,除有促进排乳和使子宫收缩的作用外,它的另一些作用正日益引起人们的关注。一些研究表明,中枢神经系统内的OT在痛调制和针刺镇痛过程中发挥着一定作用,但脊髓水平的OT对电针镇痛是否发挥作用,The influence of intrathecal injection of oxytocin (OT), anti-OT serum (AOTS) and naloxone on pain threshold and electroacupuncture (EA) analgesia in rats was investigated. The tail-flick induced by potassium iontophoresis was used to measure the pain threshold. The increase in pain theshold was observed within 70min after OT injection (100ng), and it was much more effective than that of the ACSF injection (P<0.001). The OT administration could enhance the EA analgesia. This effect was of dose-related. Although injection of AOTS did not affect the pain tereshold. it diminished EA anlgcsia. Furthermore, injection of naloxone did not influence the action of OT on EA analgesia. Our results showed that OT in spin 1 cord plays a important role in the EA analgesia, and its effects is independent of endogenous opiate peptides.
摘要:经穴—脏腑相关理论是经络学说的核心,每条经脉在体表既有特定的循行路线,又以其所属的脏腑而命名,正如《灵枢·海论篇》记载:“夫十二经脉者,内属于脏腑,外络于肢节”,表明经络与脏腑是不可分割的一个整体。“心主手厥阴心包络之脉,起于胸中,出属于心包络……,是主脉The theory of acupoint-Zangfu correlation is one of the essential contents of the doctrine of Channel and Collateral. Being based on this theory, a study has been done from the experimental research point of view in our laboratory since 1979, to approach the specific interrelationships between some acupoints on the pericardial channel and heart, as well as their functional regularities, and has served for clinical practice, which provided the basis for the research on the connective pathways between the pericardial channel and heart.
摘要:文献报道艾灸治疗关节炎和缓解关节痛有明显疗效。为深入探索其作用机理,本文以福氏佐剂诱发的关节炎(Adjuvant Arthritis,AA)大鼠为病理模型,观察艾灸对患侧关节肿胀程度,炎症病理过程及血浆中分子物质含量的影响。中分子量物质(以Adjuvant arthritic (AA) rats were used as the experimental model and the thickness of pedal pad, the circumference and the pathological (ligth microscopic changes of the ankle joint as well as the plasma content of middle sized molecules (MSM) were studied before and at subsequent experimental days after moxibustion (once a day for 6 days, on Shenque acupoint). The results showed that moxibustion reduced the inflammatory reactions significantly in comparison with that of the control group.
摘要:胃溃疡是一种常见的疾病,保护胃粘膜免受损伤是人们关心的问题。但是,胃粘膜细胞保护作用的机制迄今尚未阐明。祖国医学认为“足三里”是强壮穴;现代研究认为针刺作用其机制之一可能与植物神经有关。为此,我们用浸水引起的大鼠应激性胃In this paper, changes of neurotransmitters and the protective effect of acupuncture on gastric mucosa have been studied by the histochemical methods of cholinesterase and catecholamine on 30 pairs of Vistar rats. 1. Sequential medical trials on rats of water-immersion induced gastric ulceration show that there was a protective effect of electro-acupuncture on gastric mucosa and it was statistically significant. 2. Under the protective effect of acupuncture on gastric mucosa, finally, both the cholinergic and adrenergic nerves undergo significant inhibition.
摘要:关于感觉运动皮层(SM)在痛觉调制中的作用,以往有着不同的报导。上海生理所针麻组工作表明,切除兔SM后,对痛阈和针刺镇痛效应均无明显影响;韩湘文等在冷冻猴体感Ⅰ区后,表现为感受野痛阈的The purpose of the experiment was to study whether the effects of electroacupuncture (EA) on neurons in nucleus raphe magnus (NRM) were influenced by lesion of different areas of sensorimotor cortex (SM) in rats. Unit discharges of NRM and their nociceptive response to stimulaion of tail tip were recorded extracelluilarly with glass microelectrode. The excitatory type neurons of NRM were selected using of the experiments.
摘要:曾有报道,中枢特异和非特异投射系统均参与针刺镇痛的整合作用,其中后者可能起主要作用即。在针刺镇痛的下行调节机制中,本实验室曾证明猫的大脑皮层SII区、SI区和十字沟前区均不同程度地参与对丘脑非特异投射系统髓板内核群的下行调节,本文试图探讨丘脑特异投射系The present study was designed to investigate the relationship between the prceruciate cortex (PreCtx) and the ventral lateral posterior nucleus (VPL) of the thalamus in the mechanisms of acupuncture analgesia. Neuronal responses in the nucleus VPL to electrical noxious stimulation of the superficial peroneal nerve were extracellularly recorded. Lidocaine was topically applied at PreCtx. Twenty minutes after the application electroacupuncture (EA) was employed at "Zusanli" and "Huantiao" points for 5 minutes.
摘要:自70年代初开始用激光穴位照射(也称激光针或光针)治疗疾病以来,已较为广泛地应用于临床各科。如用于治疗前列腺炎、盆腔炎、乳腺炎、口腔溃疡以及肩周炎等,都取得了较好的消炎止痛作用,甚至还应用于针麻手术。在实验研究方Based on the analgesic effect of laser therapy in clinic, the effect of laser irradiation at acupoints on the experimental arthritis in rats was further observed. The experiments were carried out on Wistar rats, which were divided into three groups: The normal group (n=6):without any treatment. The laser group (n=8): 24 hours after an injection of Freund's adjuvant, the typical symptoms of acute arthritis (red, swelling, pain and hyperalgesia) occured. Then transcutaneous irradiation with a low power Helium-neon laser (3mw, 6328A) at
摘要:丘脑束旁核(Pf)在疼痛信息的传递,感觉和整合过程中起重要作用,这已被大量的实验资料所证实,但既往的工作多是在正常动物上进行的。我们曾观察到大鼠在局部注射弗氏完全佐剂诱发急性关节炎后处于痛敏状态,表现为电刺激尾尖引起的嘶叫阈降低,患肢局部辐射热引起的缩肢阈降We have previously demonstrated that during acute arthritis in the rats induced by local intraplanter injuvant, there are dramatic alterations in the behavioral responses to noxious stimulation. The purpose of this study was to observe the changes in responses of parafascicular nuclei (Pf) neurons during acute arthritis and effect of acupuncture (EA) in the rats. It was shown that: (1). for the whole populations of somatosensory neurons there was no statistical significant between arthritic rat and normal rat (P>
摘要:应用多种方法对经络的循行路线进行了检测和显示,证明其行程与古典的经络路线基本一致,结果稳定,可重复。但是,显性感传的经络现象在人群中只占25%左右,而人群中大多数是属于隐性感传,应用生物物理学方法已观察到皮肤低电阻点(穴位)循About twenty five percent of people have the typical phenomenon, i. e. a specific feeling propagating along the channel course during the application of needling or other stimuli on Jing acupoint. These characteristics are named marked PSC. About seventy five percent of people with no prominent propagated sensation. We concerned about how to change the obscure appearance into obvious. Combining applied knocks,measurement resistance and record electric current
摘要:已有研究证明正常人与患者以及动物的体表部存在循经低阻线。为了探讨这种现象的形态学基础,我们应用法沃尔斯基浸银染色法,对10例人循经低阻线下和其旁边对照区的皮肤内神经成分进行了连续切片的观察和计数,发现低阻线下方皮肤与对照区皮肤In order to find out the morvhological basis of the low impedance line(LIP) along meridian of the human skin, 10 cases of the skin on the LIPs along the spleen and stomach meridians were studied by the method of Farworsky silver impregnation. It was discovered that the mean numbers of the nerve bundles, nerve fibers and nerve endings in the skin along the LIP and their control areas were 509:378, 298:244, 198:148 respectively. Through statistic treatment it was