最新刊期
1990年第3期
- 摘要：大量临床实践表明穴位电针可以引起明显的镇痛作用,甚至达到可以进行手术的程度。祖国医学认为针刺穴位可以通过调整阴阳,疏通经络,调和气血而达到解除疼痛和治疗疾病的作用。经络的本质是什么? 是否是千古之迷? 实际古人已在肉眼下见到了In recent years I am interested in the role of nucleus raphe magnus(NRM)in acupuncture analgesia,NRM is the one of important deseending inhibitory systems inelude in the intrirtsie analgesie systems in brain,and we gave more systematic study on the question.The primary results are as follows: 1.Experiments were perfomed on male rats,unit discharges of NRM were recorded extracellularly with glass electrode.The neurons respond to)noxious912|0|1更新时间：2023-08-11
- 摘要：阑尾炎是外科的常见病。采用针刺麻醉施行阑尾切除术具有安全、有效、无副作用、恢复快,是一种值得推广使用的麻醉方法。但临床实验中针麻阑尾切除术、手术虽小,“三关”俱全,因此,探索克服针麻阑尾手术的(镇痛不全,肌肉松弛和内脏牵拉Appendicitis is a commonly and frequently cncountcred discasc in surgery department.Appendectomy under acupunrture anesthesia(A.A)is save and effective,casy and economocal, and helpful to recover with no side effects to patients,organism.This manipulation of anesthesia is worth applying and popularizing.Though appendectomy is a small-scale operaation in clinical practices,677|0|0更新时间：2023-08-11
- 摘要：在针刺麻醉下行疝修补术有一定优点,在小儿与老人尤为明显,但针麻有时肌松不够,使修补有困难,这是针麻疝修补术在临床上应用不多的主要原因,而肌松不佳主要还是镇痛不全引起的。为此,我们主要采用三个措施,使针麻疝手术成功率有所提高。第一是辩证施针,保持术中最佳得气,即按手术步骤有计划地提前改变电针波型和刺激In 30 cases or herniotomy under acupunclure anethesia,a seties of methods was applied,such as acupoint selection and needle manipulation which based on differentiation of symptoms and sigms of TCM,maintenanice of bebt needle sensation and small dose of fentanyl(<3μg/kg),droperidol(<0.1mg/kg)which were obviously synergistic with acupuncture.Because of the adjuvants and improvement of the operative technique,the rate of success reachen 93.3％,the rate of excellent results(Grade I)came to 66.6％,and the rate of good restilts(Grade II)26.7％.The fluctuation of blood pressure was lower than that of the centrol group.Especially the approach or acupuncture anesthesia was supcrior in the cases of senile patients with hypertension.899|0|0更新时间：2023-08-11
- 摘要：自从1975年杜焕基等报导损毁中缝大核(NRM)后明显减弱针刺镇痛效应,Oliveras等报导刺激NRM可产生明显镇痛和Proudfit等报导损毁NRM减弱吗啡镇痛效应以来,围绕着NRM在痛觉调制中的作用,国内外许多学者进行了广泛的研究,Mayer等和Fields等分别于1976年和The article reviews the main results of recent years study on the relationship between neurons in nucleus raphe magnus(NRM)and moving reflex evoked by noxious stimulation,including:1.Relative phasic discharge frequency change of on-cell and off-cell in NRM occurred when tail-flick reflex(TF)evoked by noxious stimulation.The relative phasic activaty of on-cell and off-cell in NRM was deerased or lost when TF was inhibited by brain stimulation and morphine analgesia.The data suggested that on-cell and off-cell in NRM participated in descending inhibition on spinal cord.2.The initial EPSPS on neurons of NRM always occurs after the initial digastric EMG elieited by tooth pulp shock.3.there is a positive feedback loop of reciprocal excitation befween descending pathway ftom NRM and ventral horn neurons projecting to NRM of spinal cord.It was suggested that motor neuron pool in spinal cord possible involved in the mechanism of descending inhibition from the NRM.794|0|0更新时间：2023-08-11
- 摘要：随着针刺镇痛原理研究的开展和对隔区研究的不断深入,提示隔核在疼痛调节方面有重要作用。隔核对疼痛的调节与其内部所含递质有关,也可能与脑内某些与疼痛有关脑区的纤维联系有较密切的关系。大鼠隔The efferent projections of septal nuclei from the brain areas relating to pain in the rat were studied with WGA-HRP and HRP methods.The results are obtained as follows:The septal areas project widely to some brain arease relating to pain,for instance,locus coerules,raphe nuclei,periaqueductal gray,thalamus,hypo thalamus,habenular,amygdaloid complex,cingulate cortex and hippocampus ets,but the projections of medial septal nucleus,lateral septal nucleus and diagonal band nucleus aro different.It is possiblc that these fiber projections aro one of the morphological basis of septal nuclei for regulating pain.832|0|0更新时间：2023-08-11
- 摘要：导水管周围灰质(PAG)、中缝大核(NRM)、脊髓下行抑制系统在针刺镇痛中的作用已为许多生理研究所证实,电针刺激可能通过激活PAG和NRM不同的神经递质系统而发挥镇痛作用。形态学研究揭示PAG腹外侧部和NRM不仅含有多种生物胺类、肽类和乙酰胆碱神经元和纤12 Wistar rats(220-250g)were divided into control and experimental groups.Pain threshold was determined by WQ-gE Pain Threshold Measuring Apparatus.EA was applied at bilateral"Zusanli"points.The animals showing EA analgesia and the control animals were sacrificed and the ventrolateral part of PAG and the NRM were taken out for electron microscopic observation. The peripheral region of ventrolateral PAG(PAG-PR)aud the NRM contained a wide variety of cell types and synaptic relationships.The neurons and axo-dendritic synapses of the PAG-PR and NRM were analysed in EA and control groups.In EA analgesia group,the clear round vesicle-containing presynaptic boutons and the presynaptic bouton with clear round vesicles and granular vesicles showed a significant decrease of their vesicle content.Part of the mitochondria and endoplasmic reticulum in the neurons appeared the expanded profiles.These ultrastructural changes of the PAG and the NRM during EA analgesia may indicate an increased release of acetylcholine,biogenic amines and/or pepride neurotransmitters and that the neurons were in active functional state.1061|0|4更新时间：2023-08-11
- 摘要：目前,耳针的机理尚未十分清楚,其作用于外周的基础是什么还不明确。现代解剖学研究表明支配耳廓神经有属躯体神经,如耳大、枕小神经;有属颅脑神经,如迷走、舌咽、面及三叉神经的耳支。此外,还有交感神经等支配。以上神经与耳针作用的This invcsligation was pcrformcd with thirty adult rabbits which dividcd auricular vagus, great auricular, cervical sympathcric and all auricular denervation.By gastrointestinal electro-physiologic methods, the changes of gastroiutestihal electric activity in corpus, antrum, dudenum and colon were observed with ear needing to evaluate the mechanism of function of auricular point. Results: In intact car innervation,the changes of gastrointestinal electricactivity on car needling were obvious (P<0.05—0.01). While the one with carnerve sected showed that influence of ear acupuncture still remaincd, but whenthe whole auricle was dencrvatcd the influcnce of car needling on gastrointestinalelectric activity obvicusly deceased or disappeared, pre-and post needing thechanges on gastrointestinal electric activity were not statistically different (P>0.05). Recordings at the four parts of digestive tract gave similar rcsults infrequancy, amplitude, inotility index, action area integral. Exerting stimulation on gastric vagus or sympathetic nerves could bring about double phase modulatory (excitory or inhibitory). The above revealed that the functions of car point in diaghosis and therapy is not due to one kind of nerves in periphery. The functions of ear point at innervation may be in its entirety. It was rcportcd that function of car points has something to do with auricular vagus or great auricular or sympathetic nerves, but,this is only one side of the matter. Moreover,since auricular point are associated with various propagatal tracts and with modulation of nerve centers, their mechanism is very complicated and needs to be further studies.997|0|1更新时间：2023-08-11
- 摘要：同名的手经与足经有一定的相关性,不仅古代文献有所论述,近代研究也有所证实。手阳明大肠经的合谷穴和足阳明胃经的足三里穴在面瘫的治疗中均为常用穴位,比较对手经与足经穴位针刺后面瘫患者面部温度的变化是本文的目的。本文采用红外热像方法,以面部温度作指标,对针刺单侧合谷和足三里前后面部的升温效应进行分析With thermographic techniqu, We observed changes of the facial temperature after acupuncturing Hegu (L14) and Zusanli (S36) in 65 patients (103 cases in all) with facial nerve paralysis. The observation showed that the average of Hcgu group was higher than that of Zusanli group. The result explained that the offect of acupuncture at points of hand-yangming "meridian was bigger than that of foot-yangming meridian on the facial temperature.1015|0|4更新时间：2023-08-11
- 摘要：针刺“足三里”穴对胃功能的调整作用,国内外已有大量报导,但主要是以胃运动、胃液分泌或胃电为指标,以中枢神经系统内神经元放电为指标尚未见有报导。我们以往的工作表明,扩张胃的外周传入对下丘脑外侧区(LHA)摄食中枢的Previous sludies in our laboratory have shown that some unit discharges of the neurons in Feeding Centre of the lateral hypothalamic area (LHA) may be inhibited by distcnsing stomach. The present study was performed to observe the effect of electro-acupuncture of"Zusanli"piont on the discharge-ineibftory reaction induced by distensing stomach in rats. Among 52 unit discharges observed,36 (69.2%)showed that electro-acupuncturing"Zusanli" piont abolished the inhibitory reaction indiced by distensing stomach. The durations of the effect range from 5 to 15 minutes. These results indicate that the somatic input from "Zusanli" pisnt may influence the reactivity of Feeding Centre of LHA to the activity of stomach.914|0|1更新时间：2023-08-11
- 摘要：我们以前的工作表明,电针能明显提高因踝部注射弗氏完全佐剂引起的关节炎大鼠的痛阈,抑制其背角神经元的伤害性诱发放电,并且发现在急性佐剂性关节炎大鼠注射纳洛酮后伤害性反应明显增强,提示有中枢神经系统内源性抗痛物质的激活。那么在大鼠的行为表现上,这种内源性镇痛系The dynamic changes of the pain thresholds (Heat-WithdrawaI Latency,HWL and Stimulation-Vocalization Threshold, Voc) in the adjuvant-induced arthritic rats and the effects of EA on the pain thresholds, skin temperature and the circumference of the diseased ankle were observed. Both pain thresholds were obviously decreased in affected limbs in EA and control groups. But in the normallimbs, HWL decreased and Voc,no changed. In EA group,the ankle circumference and skin temperature were markedly lower than that in control group.The increase of the body weight was much more obvious than that in control group. Our experiment revealed that EA could not only increase the pain thresholds, but also improve the pathological changes in the inflammation of the ankle, the mechanisms of the changes of the pain thresholds and the effects of EA in the arthritic rats were discussed.870|0|8更新时间：2023-08-11
- 摘要：我国古代的针灸学专著对针刺穴位的刺法和深度有较具体的记载。近几十年来,对针灸机理进行了广泛的研究,针刺穴位的深度问题也引起了人们的兴趣。我们实验室以往的工作中证实,针刺大鼠的“环跳穴”可以引起镇痛效应,同时观察到Fifty-four healthy male,adult rats were divided at random into three groups: deep and shallow acupuncture groups and the controls. After acupuncturing, the pain threshold were measured and the animals were sacrificed for histochemical examination in locus coeruleus. The pain threshold of deep acupuctured animals was elevated but that of shallow acupunctured and controls were not. The difference between them was significantly. The amount of AChE and RNA of perikaryons in locus coeruleus of mentioned three groups were measured with micropiotometer. The reaction of AChE and RNA in deep acupuncture group increased significantly in comparison with that of control as well as shallow acupuncturing group.These reactivities of the latter two groups were similar to each other. The results indicated that the effect of acupuncture might be involved in the stimulating of the deeper structure of acupuncture point.874|0|2更新时间：2023-08-11
- 摘要：我们在佐剂诱发的急性关节炎大鼠上研究的结果已经表明,电针穴位和电刺激皮层体感运动Ⅰ区(SmⅠ区)均可明显抑制关节炎鼠丘脑束旁核(Pf)神经元的伤害性反应,用利多卡因局部阻滞SmⅠ区时,电针对Pf神经元伤害性反应的抑制作用削弱,说明皮层SmⅠ区对Pf神经元的伤害性反应Using the adjuvant-induced acute arthritic rat as a pain model, we have previously shown that the Sm I area is implicated in the inhibitory effect of acupuncture on lhe afferent nociceptive information of parafacicular nuclei (Pf). The prupose of this study was to determine whether acetycholine (ACh) participates in this modulatory process. Experiments were conducted with adjuvant-induced acute arthritic rats and cxtracellular recordings from pf were obtained through microelectrodes stereotaxically. The results showed that: (1) After intraperitoneal-injecting atropine (Smg/kg), the effect of stimulating SmI on nociceptive responses of Pf neurons was decreased,while it was not decreased if saline was administered. Compared in the same neurons,the difference of nociceptive responses at 0′to 15′after cessation of stimulating SmI was staistically sigificant. This finding indicated that ACh was inmolved in descending modulation of SmI.(2) The effect of acupuncture was decreased after intraperitoneal-injecting atropine (Smg/kg), while it was not decreased if saline was administered.The difference of nociceptive response was statiseically significant at 0′to 10′ and 20′ to 40′ after cessation of EA in comparison between the background of atropine and saline. It indicated that ACh was involved in acupuncture analgesia. These results suggest that ACh may be participated in acupuncture analgesia as a neurotransmitter of the corticofugal modulation of pain.932|0|6更新时间：2023-08-11
- 摘要：针刺信息的外周传入途径是针刺镇痛原理的重要组成部分。实验证明针刺镇痛效应是由深部感受器及其传人纤维受刺激引起的,针刺可以兴奋各类神经纤维,但哪类纤维是传入针刺镇痛信息的,主要有两种看法:(1)认为Ⅱ类纤维与针刺镇痛有关;(2)认为Ⅳ类纤维(C-纤维)In this experiment, the rats treated with capsaicin (50mg/kg) s. c. on day 2 of liqc were used 12 weeks after injcction. The levels of substancc P(SP) in sciatic nerves and dorsal spinal cords were measured with radioimmunoassay to evaluate the extent of C-affercnt fibers damaged by capsaicin. The results as follows: (1) the levels of SP in the sciatlc nerve and the dorsal spinal cord are decreased by 69％ and by 62％ respectively, indicating the degeneration of the primary C-afferent fibers is very massive; (2) the average of basal tailflick latency (immersing in 50°C water) is prolonged 105% as compared with the control; (3) after electro-acupuncture, the average of tail-flick latency of the capsaicin treated rats is increased by 81%, while that of the vehicle treated rats increased by 54％. These data suggest that C-afferent fibers substantially mediate the transmission of noxious thermal stimuli, but is unncccssary for the transmission of acupuncture messagc to induce analgesia.965|0|3更新时间：2023-08-11
- 摘要：据报道P物质(SP)在脑内具有镇痛作用,但这些资料多数是将外源性SP注入脑内而得出的结论。虽然在针刺镇痛过程中脑、脊髓内SP含量具有明显的变化。然而,在实用一些递质或某些镇痛物后,脑This invcsligation was pcrformcd with thirty adult rabbits which dividcd auricular vagus, great auricular, cervical sympathcric and all auricular denervation.By gastrointestinal electro-physiologic methods, the changes of gastroiutestihal electric activity in corpus, antrum, dudenum and colon were observed with ear needing to evaluate the mechanism of function of auricular point. Results: In intact car innervation, the changes of gastrointestinal electric activity on car needling were obvious (P<0.05—0.01). While the one with car nerve sected showed that influence of ear acupuncture still remaincd, but when the whole auricle was dencrvatcd the influcnce of car needling on gastrointestinal electric activity obvicusly deceased or disappeared, pre-and post needing the changes on gastrointestinal electric activity were not statistically different (P>0.05). Recordings at the four parts of digestive tract gave similar rcsults in frequancy, amplitude, inotility index, action area integral. Exerting stimulation on gastric vagus or sympathetic nerves could bring about double phase modulatory (excitory or inhibitory). The above revealed that the functions of car point in diaghosis and therapy is not due to one kind of nerves in periphery. The functions of ear point at innervation may be in its entirety. It was rcportcd that function of car points has something to do with auricular vagus or ret auricular or sympathetic nerves, but, this is only one side of the matter. Moreover,, since auricular point are associated with various propagatal tracts and with modulation of nerve centers, their mechanism is very complicated and needs to be further studies.1036|0|0更新时间：2023-08-11
- 摘要：近年来大量实验表明,广泛分布于中枢神经系统的促甲状腺素释放激素(TRH)参与多种生理功能的调节。脑室微量注射TRH,可提高小鼠的痛阈,提示TRH可能参与中枢镇痛过程、伏核、杏仁核及尾核是针刺镇痛和痛觉调制中的重要结构。免疫Glass microelectaod recording method was used to investigate the effect of thyrotropin-releasing hormone(TRH) into nucleus accumbens, nucleus amygdaloid or nucleus caudate-putamen on unit discharges of pain-excitation neurons (PEN) in nucleus parafascicularis of thalamus in rats. The results showed that: (1) TRH injccted into the nucleus accumbens results in a significant ihhibition of pa- in discharges of PEN in nucleus parafascicularis. But injection of TRH into nuc- leus amygdaloid, nucleus caudate-putamen had no significant effect. (2) Pretreat- ment with auropine abolished the inhibitory effect of TRH. (3)'Pretaeatment with haloperidol also adolished the inhibitory effect of TRH. (4) Pretaeatment with naloxone, propranolol or phen-tolamine did not affect the inhibitory effect of TRH. The results mentioned above suggested that nucleus accumbens could be a sp- ecial area in response to TRH and the effect of TRH seems to be involved in both cholinergic M-receptor and dopamine receptor.790|0|0更新时间：2023-08-11
- 摘要：单纯性肥胖是一种常见的,多发的疾病之一,多数患者伴有脂质代谢紊乱。有关针灸对单纯性肥胖患者血清高密度脂蛋白胆固醇(HDL-C)的作用尚未见有人报道,我们对单纯性肥胖患者针灸前后血清HDL-C进行了测定,阐明针灸对单纯性肥胖患者HDL-C的作用,为防治肥胖并发心血管病For the purpose of understanding regulatory effect of acupttGcture and mox- ibustion, we have observed the changes of the obese indices and the lipid Indices in 196 semple obesities before and after the acupuncture and moxibustion. The results showed that a good therapeutic effect of acupuncture and moxibustion on obesity was obtained, At the same time, there are the benign regulatory effect of acupuncture and moxibustion on the lipid metabolism and high densitry lipopro- rein cholesteral.1048|0|2更新时间：2023-08-11
- 摘要：皮肤阻抗能否作为检测经络循行路线的一个客观指标,是多年来人们一直在研究的一个问题。虽然国内外都已做了不少的工作,但意见仍然比较分歧。其中一个原因,就是对测试方法还缺乏充分的论证。针对目前皮肤阻抗研究工作中存在的问题,1987年,我们曾对测试方法作了一些重要的According to the requirement of channel rerearch, a system for rhe measur- ement of skin impedance had deen designed and a series of experiments to check the reliability of this system had also been done. The facts demonstrated that the pressure exerted by rhe exploring electrode, the duration of switch-on as well as the number of timei of repeated measurements all showed no conspicious influences on the skin impedance. The results are stable and reliable. Moreover, the measurement and data processing are controlled by microcomputer. Thus, the method of measuremenet of skin impedance along the chanuels has been developed to a higher level. Under the conditions of our experiment, the impedance of the low skin imp- edace points (LSIPs) are about 108kΩ, which are quite low than that of the non-LSIPs around them. The difference between the two is highly significant. Both the impedance of LSIPs and non-LSIPs are stable, without marked variation. These results provide the prerequistics indispensable for the further observation on the feature of the distribution of LSIPs.837|0|5更新时间：2023-08-11
- 摘要：有些作者认为,应用红外成像技术可以客观显示某些穴位和经络现象。蒋来等报道,用20％当归注射液注入腧穴,有4例主诉出现循经性热感者,其红外热像图显示出一条与主诉感传线相一致的高温亮带,且亮带的辉度与热感的程度呈正变关系;而3This paper reported the observd results on changes of the infrared thermal image of upper extremity induced by needled“Hega” (LI 4), “Daling”(P 7) and “Neiguan” (P6) points. The results indicated that 10 out of 23 cases whose higher and middle temperature bands of upper extremity distribted along the “Daehang” (Large Intestine) channels, when they felt phenomena of propagated sensation along the “Dachang” channels induced by needled “Hegu” points. Those effects did not appear in the objects who didnot feel PSC along the “Dachang" channels induced by needled points. Above results provide an objective basis for the phenomena of channels and suggest that the phenomenon of PSC is an objective fact in human body.905|0|10更新时间：2023-08-11
- 摘要：面部是多条经脉所过之处,针刺远端穴位用于治疗面部疾患并可取得疗效,是以经络理论指导临床实践的具体体现。“面口合谷收”已成为每位针灸医生最熟知的取穴治疗经验了。许多面部疾患患者接受针刺治Thirty three patients and nine volunteers were observed. 18 out of 33 pa- tients felt PSC and Qi reaching to face induced by needled points, The QiRA rate was 80% in patients with face diseases, During acupuncture “Hcgu” (LI 4) points, most of the patients felt PSC re- aching to their faces and sensed heat in face, The infrared thermal image demo- stated that the temperature of face skin increase and the hyperthermal areas co- incided basically with the pathway of “Yangming” channels. Those effects were more than the effects of the other objects who didn’t feel PSC or sensed Qi reaching to face induced by needled “Hegu” (LI 4) or “Daling” (P 7) Points, The difference between the two groups was statistical significant. The tcmpere- ture rising responses induced by needled points were not the results of natural fluctuatsono The above results indicate that the PSC and QiRA is objective cxisteace.909|0|5更新时间：2023-08-11
- 摘要：艾滋病是获得性免疫缺陷综合症(AIDS)的简称。本文从中医和针灸的学术观点,综合有关资料,试图对艾滋病的病因病机及针灸治疗等进行探索。 (一) 病因病机依据本病的病原学和流行病学的特点与832|0|1更新时间：2023-08-11
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