摘要:周围性面神经麻痹是基乳突孔内急性非化脓性的面神经炎症所致一侧面部表情肌的瘫痪,亦称Bell’s麻痹。是因面部感受风邪,致使风邪中于经络而引起面部肌肉瘫痪的病Sixty-Three cases with facial paralysis were treated mainly by acupuncture combining with point injection. The main points selected were Yangbai (GB14), Wai Jingming (BL1), Sibai (ST2),Yingxiang (LI20), Dicang (ST4), Jiache (ST6), Quanliao(ST18) and Qianzheng. The points were used alternatively. Auxiliary points: for type of deficiency of both qi and blood, Zusanli (ST36), and Sanyinjiao (SP6) were added; for type of disharmony between Ying and Wei, Fengchi (GB20) and Hegu (LI4) were added; for type of stagnancy of qi and blood, Weiguan (TE5) and Taichong (LR3) were added; for type of wind-heat stagnating collaterals, Yifeng (TH17) and Yanglingquan (GB34) were added. 10 out of 60 cases, which showed no remarkable effectiveness after two courses, injection of vitamin B_1 and vitamin B_(12) to facial points combined with Hegu (LI4) point on opposite side was performed. Therapeutic results: 31 cases(49.2%) were cured, 15 cases (23.8%) markedly effective, 16 cases(25.4%) effective and 1 case (1.6%) ineffective.
摘要:本组病例行阑尾切除术,随机以针刺麻醉40例,硬膜外麻醉40例进行比较术中镇痛效果,生命体征的平稳情况,术后胃肠功能的恢复时间,排气时间,镇痛药物的使用情况,抗生素的使用及切口愈合情况,住院天数以及观察两种麻醉方法的术中镇痛及术后It was a clinic comparative observation of the effects between acupuncture and epidural anesthesia in appendectomy. Eighty patients with appendicitis were randomly divided into two groups, each of 40 Patients. The results were no significant difference between two groups in successful rate. It is convinced that acupuncture on Zusanli points (ST36) has analgesia. There were less respiratory depression, hypotension,cardiac arrhythmia and less amout of liquid infusion needed than that of the epidural block during operation. Furthermore, in fhe group of acupuncture anesthesia, the intestinal gas excreted earlier, the analgetics and antibiotics adiministered were less and the rate of the wound infection were reduced after operation. These postoperative effects were significantly better than the controls. As it is of clear-cut effects of anesthesia by acupuncture with main points Zhusanli and auxilliary points Hegu (LI4) and less interfered life sign in the operation,thus it is desi rable to use acupuncture anesthesia in appendectomy.
摘要:大脑皮层是否参与疼痛的感受长期以来是一个争议的问题,但近年来记录皮层发诱电位和单个神经元活动的方法已证明伤害感受性信息可以达到皮层体感区(SⅠ1. The effect of electro acupuncture (EA) on the responses of single SI cortical nociceptive neurons to peripheral natural stimuli were observed in unanesthetized and paralyzed rats. 2. After EA, the responses to noxious mechanical and/or thermal stimulation reduced markedly in 14 (70%) out of 20 neurons tested, and slightly increased or unchanged in the remaining 6 neurons, as compared to the responses before EA. 3. In contrast to the variation of nociceptive responses, the responses to innocuous mechanical stimulation increased in 9 neurons and unchanged in other 9 neurons, while deceased in only 2 neurons. 4. A small portion of the neurons were activated by EA stimulation, while their responses to noxious stimulation were inhibited. 5. It is considered that the selective inhibition of the nociceptive responses of SI cortical neurons might be a part of the mechanisms of acupuncture analgesia.
摘要:癫痫是危害人民健康的常见病,其发病机理复杂。针灸治疗癲痫历史悠久,至今仍在临床广泛应用,表明针灸治疗癫痫有一定疗效。近年虽有一些用针灸治疗癫痫机制研Epileptiform discharge induced by microinjection of penicilin in the rat's Amygdala was attenuated after acupuncture of certain "acupoints", as revealed by reduction of frequency and amplitude. The effect of acupuncture was reversed by microinjection of naloxone or 3M-P into peritoneal cavity, thus suggesting the participation of endorphin and GABA in antiepileptic action of acupuncture.
摘要:我们实验室的工作曾报导,刺激猫的皮层SⅡ区、SⅠ区或十字沟前区可抑制丘脑髓板内核群神经元的伤害性反应及针刺镇痛效应。相继刺激大鼠的皮层SmⅠ区也获We have found that after intraperitoneal injecting atropinc the analgesic effect of both stimulating Sm I cortex and acupuncture were decreased. It suggests that acetylcholine (ACh) may be involved in the corticofugal modulation of pain. In order to elucidate this idea the effects of stimulating Sm I cortex on tail flik latency (TFL) after ventrical microinjecting atropine were investigated. The experiments were carried out on Wistar rats. Under the state of anaesthesia a pair of silver ball electrodes were put on the dura for electrical stimulating Sm I and the ipsilateral ventricle was cannulated for microinjecting atropine. Recordings were made 5—6 hours or 24 hours after operation. Immediately after cessation of stimulating SmI and 1'、2'、3.5'、5'、7.5'、10' and 15' later TFL were measured consecutively. The results were as follows: 1. The mean value of TFL was 2,44±0.11 sec (n = 20). It was prolonged (p<0.05) within 0'-5' after stimulation of SmI. Therefore, it indicated that analgesic effects were produced by stimulating SmI cortex. 2. It was found that under the background of microinjecting atropine (10 μg/2μl) TFL remained unchanged after stimulating SmI cortex (n = 10, P> 0.05). There was a significant difference between the two treatments: simple stimulating SmI and atropine plus stimulating SmI at the same animals in TFL (P<0.05) within 0' and 1' after cessation of stimulating SmI. It indicated that the analgesic effects of stimulating SmI cortex were decreased by blocking Mreceptors. 3. Under the background of microinjecting normal saline. The analgesic effects still could be observed after stimulating SmI. The results were just like those obtained in simple stimulating SmI at the same animals (n=10). 4. Comparing atropine group with normal saline group it was shown that there was a statistical difference in TFL at 0' and 1' between the two groups (P<0.05). It suggests that ACh is involved in the corticofugal modulation of pain.
摘要:早在一百多年前,人们就已经认识高压氧(0HP)对中枢神经系统具有毒性作用,可引起惊厥反应。然而,关于OHP惊厥的发病机理以及有效地防治OHP惊厥等问题,至今This paper reports the effect of acupuncturing "Renzhong" (GV26) and "Chengjiang" (GV24) points on OHP-induced convulsion in mice. The results are as follows: 1. Convulsion induced by 6 ATA OHP were accompanied with a decrease in the brain GABA concentration. 2. When electro-acupuncture was applied for 15 minutes prior to exposure to hyperoxic chamber, the latence of convulsions was lengthened and the symptomes of seizures were alleviated. Besides, the brain GABA concentration was also elevated remarkably. 3. Administration of vitamin B_6 enhanced the effect of acupuncture on convulsions and icreared brain GABA concentration. 4. The latence of convulsions was well correlated with the GABA concentration of the brain (r = 0.9867). The above results indicate that acupuncture may elevate endogenous GABA levels in the brain and prevent the hyperbaric-oxygen-induced the decrease in the brain GABA content. Therefore. It is of protective effect against oxygen convulsions. Vitamin B6 may facilitate the effect of acupuncture by imprpving the GABA metabolism in the brain. In short, the effect of acupuncture against oxygen convulsions may be closely related to the increase in the brain GABA levels. OHP. high oxvgen pressure
摘要:由于嬰幼儿的免疫球蛋白水平较低,6个月时升到成人的50%,直到10岁左右才接近成人水平,所以婴幼儿易感染。特別是因为婴幼儿IgA较低,故急性支气管炎This report described the clinical observation of pasting acupuncture with Chinese herbs applying in 72 infant acute bronchitis cases and regarding to the humoral immune substances such as IgA, IgM, IgG, Complement C_3 The result shows high cure and improve rate. The curative effect of infantile group is higher than that of childhood one (x2= 6.501, 0.05>p>0.025). All indexes of humoral immune substances, especially IgA, were increased after treatment (t = 10.50, p<0.01).
摘要:机体机能随时间变化的节律性影响着针刺效应的发挥已为众多实验证实。而昼夜节律究竟如何影响针刺效应,怎样利用其作用规律提高针刺疗效的研究至今未见报道。本Taking rats and mice as subjects, observation had been made on the protecting action of acupuncture to prevent the gastric mucosa from experimental injury. The pH value (by accurate test paper), gastric acid output (by titra- tion), the secretion of PG in gastric mucosa (by radioimmunoassay) were observed altogether at 1-3h, 5-7h, 9-11h, 13-15h, 17-19h and 21-23h. All of the above indices were changed along with the alternation of day and night. And the effects of acupuncture on these indices were different when giving acupuncture at different times. The action of acupuncture to prevent experimental gastric ulcer was also different at different times. It is the general regularity that puncturing at the acrophase of circadian rhythm, the effect was mainly inhibitory, while puncturing at the valleyphase, the effect was mostly excitatory. Therefore, utilizing the influence of the various phases of circadian rhythm on the acupuncture effect, to choose the optimum time giving acupuncture could be one way to promote the acupuncture curative effect.
摘要:内脏的感觉由植物性神经传入,其传入神经元的胞体位于脑、脊神经节中。这早在1914年Chase和Ranson等已有研究,并被神经解剖学者所公认。70年代初,Kri-Ten adult rabbits were used in this experiment. A solution of 10—20% HRP (sigma Ⅸ, RZ= 3.2) was injected into the "Zusanli" point and the subserosa of the caecum. The uptake and retrograds transmission of HRP in the afferent neurons of both the somatic and visceral nerves were traced to the spinal ganglia. The results showed that: 1. Labelled afferent neurons from the region of "Zusanli" point were found in the spinal ganglia T_(12)—S_2 with a higher concentrauion in L_4—S_2. 2. Labelled afferent neurons from the region of the caecum were found in the spinal ganglia T_2—S_2 with a higher concentration in T_(12)—L_2. 3. The ranges of distribution of labelled afferent neurons from the regions overlaped in the segments T_(12)—S_2.
摘要:类风湿性关节炎(简称RA)属祖国医学的“痹证”范畴,是以慢性对称性、多关节表现为主的一种全身性疾病。虽然病因尚不明了,但是认为其发病与自身免疫有关。近年来的研究表明RA与细胞免疫功能缺陷和体液免疫失调关系密切。为探讨Rheumatoid arthritis (RA) is referred to the category of Bi syndromes in traditional Chinese medicine. It is regarded as an autoimmune disease, but the pathogenic mechanism is still to be clarified. In order to observe the effects of the treatment of RA with acupuncture and moxibustion on IL-2, 41 patients were divided into warming needle and point injection groups at random, and 19 healthy subjects as control group. The results showed that the IL-2 levels in two RA groups before treatment were obviously lower than that in control group (P 0.05). After treatment the IL-2 level in control group was unchanged, but increased considerably in two RA groups (P 0.01). Generally, IL-2 is considered as a very important signal for regulating immune response. Our results have shown that the decrease of IL-2 in patients with RA should be one of main causes of internal environment disorder, acupuncture and moxibustion as a stress stimulation exerts an influence on the immunity system through neuroendocrine system to improve the IL-2 production.
摘要:以躯体、内脏伤害性刺激引起中枢神经系统产生电变化方面的报导不多。为此我们选用佐剂关节炎(Adjnvant Arthritis.AA)大鼠为慢性痛的动物模型,探讨慢性Adjuvant arthirts (AA) rats were used as the chronic pain model. The cortical and hippocampal (HPC) EEG were recorded. The behaviour and local inflammatory reaction were observed. The results showed an arousal response of desynchronization of the ECoG and HPC EEG in the AA rats, the delta waves were decreased and bata waves increased significantly. However, the inhibited effect to the desynchronization were showed could be inhibited by the electro-acupuncture (EA) on bilateral Zusanli points and morphine in the AA rats. The results suggeste that the cortex and hippocampus participate in the modulating action of chronic pain, and the EA has an analgesic action.
摘要:临床上休克患者由于缺氧可导致物质代谢尤其是糖代谢的紊乱,引起乳酸血症而并发酸碱平衡失调和电解质平衡紊乱,出现酸中毒和血钾增高。血浆内pH值的相对In the present work, the changes of pH and the kalium content of blood and the effects of acupuncturing "Renzhong" on these changes were observed in rats with hemorrhagic shock. The experimental rats were randomly divided into three groups: surgical control group, shocked control group, shocked acupancture group. The blood pH was significantly decreased at maintaining shock for one hour (n = 30), P<0.01; there was no change in surgical control group (n = 15), pH decreased continually with the shock time, (n = 14). But pH tended to going up again after acupuncturing "Renzhong" for 15 min (n = 16). The content of blood kalium was increased at maintainually shock for one hour (n = 26). The content of blood kalium was significantly increased whith the prolonging shocked time (n = 12) or acupuncturing "Renzhong" (n = 14), P<0.05. But there was no clear change in surgical group (n = 15). The results suggested that the acidosis condition was slightly rectified by acupuncture via modulating the respiratory function and reducing the acidic metabolites in blood of the rat with hemorrhagic shock. But the hyperkalemia produced by shock was hardly rectified by acupuncture.
摘要:近年来国内外文献报道,中枢神经系统的催产素(OT)在痛觉调制过程中发挥着一定的作用,我们最近的工作也表明,脑和脊髓内的OT不仅可以提高大鼠的痛阈,而且能明显增强电针镇痛效应。为进The effect of oxytocin (OT) and cholecystokinin octapeptide (CCK-8) on EA analgesia was studied in rats. The increase of 20.8—39.8% and 9.0—45.0% in pain threshold was observed respectively when ICV of CCK-8 or naloxone was combined with EA, these increases were lower than that in saline-EA group significantly, while the simultaneous ICV of OT and CCK-8 or OT and naloxone in combination with EA produced the increase of 76.2~116.6% and 41.8~104.5% in pain threshold separately. These results showed that only a small part in the role of OT enhancing EA analgesia was blocked by CCK-8 and naloxone. The data suggest that the role of OT in EA was not entirely dependent upon the endogeous opiate peptides.
摘要:近年来,国内外学者提出了白细胞介素2-干扰素-自然杀伤细胞(IL_2-IFN-NKC)免疫调节网这一新理论。IL_2对TH和T_c有生长维持作用,能显著增加干扰素的生成,增The influence of acupuncture on IL_2-IFN-NKC regulatory network was investigated, experiments were performed on kidney-deficiency mice received the treatments of acupncture of "Zusanli" point. The results showed that the interleukin: (IL:), natural killer cell (NKC) activity and interferon (IFN) from the kideny-deficiency mice were lower than that from the normal mice. Acupuncture increased the levels of all the IL_2 and NKC activity, acupuncture promoted Newcastle disease virus (NDV) inducing the IFN of kidney-deficieny mice, but also induced the IFN directly. The results suggests that acupuncture could make positive adjustment to IL_2-IFN-NKC regulatory network. It provided new theoretical basis for the principles of acupuncture theory on IL_2-IFN-NKC regulatory network put forward recent years.
摘要:探讨经络实质已成为国内外学者研究的课題,近来国内外已有人应用放射性锝进行了研究,但均未进行形态学追踪。我们运用核医学示踪法由循经轨迹的宏观显示做为先The study of impendance line along channel had been perfomed with the radionuclide tracing method in 15 healthy human being and 4 guinea pigs. These images of tracer migrating routs approximately corresponded with classical courses of channel. The study proved that these line-shaped tracer migration were not by the way of lymphatic and blood vessels as well as nerves. This image of radionuclide migrating along channel may used as the guide for the observtaion of micro-autoradiography. In this study, satisfactory migrating image along the channel was also obtained by (131)I instead of (131)I instead of (99m)TC, So a new way was opend up for both macro-and micro-autoradiographic study.