最新刊期
1992年第3期
- 摘要：通过长期针麻手术临床观察我们认为,辨证分型与针麻效果有密切关系,辨证分型与针麻效果在针麻甲状腺等手术中己有报导,但有关针麻疝修补术尚未见报导。747|0|0更新时间：2023-08-11
- 摘要：腓总神经是小腿和足背的主要感觉神经,以伤害性强电刺激腓总神经可以导致动物的痛反应,如反射性下颌运动及血管紧张性收缩等,并可诱发脑内核团痛放电;痛觉Noxious electric stimulation of ncrvus pcroneus communis (PN) results in pain. It hasn't been reported that the neurons in somatosensory area I(SI) may respond to the noxious stimulation. In this paper, using intracellular microelectrode technique, we have studied the responses of neurons in SI to noxious electric stimulating PN. 33 neurons were recorded in 18 cats. 16 neurons were related with the noxious stimulation. The responses of these neurons to noxious stimulation were mainly inhibitory postsynaptic potentials (IPSP). Some neurons responded with two IPSPs. A few neurons responded with EPSP(Excitatory postsynaptic potential)-IPSPs. The latencies of the first IPSPs were short(8.25±5.90ms) and showed that the first IPSPs might be induced by the input of Aβ fiber. The latencies of the second IPSPs (In the neurons with two IPSPs) were long (60.33±6.62ms) and showed lhat the second IPSPs might be induced by the input of A6 fiber. Above results show That: 1) SI neurons can respond to the noxious electric stimulation of PN.2) The responses of SI neurons to the noxious stimulation were mainly IPSPs.3) The second IPSPs might be related with pain.717|0|4更新时间：2023-08-11
- 摘要：近十余年,越来越多的证据表明丘脑腹侧基底核(VB)内确实含有感受伤害性信息的神经元。研究又证实大脑皮层不仅可感受痛信息,还参与痛调制,大脑皮层的下行调制作用参与针刺镇痛过程。在丘In order to explore whether cortical somatosensory area 11 (SI1) was involved in descending modulation of the effect of electroacupuncture (EA) on nucleus ventralis posterolateralis (VPL), the present study was designed to investigate the influence of topical application of lidocaine at SII on the EA effects in VPL nucleus. Experiments were performed on 23 adult cats anaesthetized with pentobarbital sodium (35-40mg/kg i.p.) and immobilized with gallamine triethiodide. The single unit activities of VPL neurons were extracellularly recorded using glass microelectrodes. The results were as follows. 1. The nociceptive responses of VPL were obviously attenuated after EA at "Huantiao (G30)" and "Yanlingquan (G34)". The difference was statisically significant at 0-10 minutes after cessation of EA (n=13, P<0.001 or P<0.05), then it was gradually recovered. The results showed that EA could inhibit the nociceptive responses of VPL neurons. 2. The inhibitory effect of acupuncture on nociceptive responses were reduced or abolished after topical application of lidocaine (n=14,P>0.05). However, it exerted marked inhibition at 0-10 minutes after cessation of EA in the saline control group (n=14, P<0.05). There was a statistical difference between these two groups (P<0.05). The results showed that SII was involved in descending modulation of acupuncture effect in VPL nucleus.876|0|2更新时间：2023-08-11
- 摘要：近年来研究资料表明,主要调节血压、内分泌和植物性功能的加压素(Vasopressin,VP)也参与痛觉调制。脑室内注射VP可产生明显的镇痛作用,相反,先天性缺乏In this experment, the role of PVN in acupuncture analgesia was further investigated with electrophysiological technique. In wistar rats the unit discharge was recorded extracellularly, Noxious stimulation was applied to sciatic nerve, and the electroacupuncture was performed on acupoints "Zusanli" and "Sanyinjiao". Totally eighty-two units were recorded successfully from PVN. 49 units of them reacted to electroacupuncture with excitatory (14), inhiditory (23) or on significant effect (12). Various types of reactions including excitation (12), inhibition (6),excito-inhibition (4) or inhibito-excitation (3) were observed on 43 units during noxious stimulation of sciatic nerve. The remainder 18 units had no significant reaction. After electroacupuncture those units reacting with excitatory effect on noxious stimulation decreased their firing rate, and those with inhibitory effect increased their firing rate. The duration of nociccptive reaction was shortened after electroacupuncture in both types of units. It was suggested that electroacupuncture could influence the activities and decrease the nociceptive reactions of PVN neurons, which might be considered as electrophysiological evidence of the involvement of PVN in acupuncture analgesia.966|0|0更新时间：2023-08-11
- 摘要：传统的观念认为,红核的主要机能是调节躯体运动和肌紧张。但近年来有少量工作提示,红核与感觉的调制也有关。我们以往的工作证明,兴奋大鼠红核可使引起甩尾反The spontaneous discharges of neurons in red nucleus(RN) of rats have been recorded with microelectrode. The discharge frequency of most RN neurons was changed by nociceptive electrical stimulation of nervi peronaeus communis or nervi tibialis or by nociceptive mechanical stimulation of tail or hind leg. The electrical activities of the somatic snsory neurons in the nucleus ventrilis posterolateralis (VPL) of thalamus and of the visceral sensory neurons in the nucleus anterior and nucleus parafascicularis of thalamus have been recorded. According to the form of response to the peripheral nociceptive stimulation the neurons concerned could be divided into three types, pain-excited, pain-inhibited and pain-nonrelated. Electrical stimulating RN could change the spontaneous discharge frequency of somatic pain-related neurons of VPL and visceral painrelated neurons of nucleus anterior and nucleus parafascicularis, and could inhibit their response to somatic and visceral nociceptive stimulation respectively, but did not have influence on the activity of most pain-nonrelated neurons in VPL. The effects of electrical stimulating RN and microinjecting Ach into RN on the same pain-reated neuron in VPL were similar. The experimental results show that RN can receive the somatic afferent impulses, that the excited RN can inhibit the transmission of somatic and visceral nociceptive impulses into the thalamus, and that the analgesic effect of RN is concerned with Ach884|0|1更新时间：2023-08-11
- 摘要：8-精-催产素(8-arginine-vasotocin,AVT)又名管催产素,是松果体分泌的九肽激素,其环状结构部分与催产素(oxytocin,OT)相同,直链部分与精氨酸加压素(Argi-The Asu-AVT(1,6 aminosuberic acid -8-arginine-vasotocin) is an analogue of 8-arginine-vasotocin(AVT) which is one of pineal hormones. The effect of Asu-AVT on the pain threshold and EA analgesia was studied in rats. An increase of 16.2～41.5% in pain threshold was observed within 70 min. after ivc of Asu-AVT(75ng), while the Asu-AVT injection in combination with EA produced a significant increase of 164.6～309.1% in pain threshold, which was much higher than that in the sahne-EA group(p<0.05～0.01). The effect of Atu-AVT is analogous to that of oxytocin and arginine-vasopressin. The data indicate ivc of ASu-AVT not only elivates the pain threshold, but also enhances the EA analgesia. These results suggest that the pineal hormone, AVT may play a role in the EA analgesia.986|0|0更新时间：2023-08-11
- 摘要：肾上腺素受体具有广泛的临床意义,近年发展迅速。脑内去甲肾上腺素神经递质,主要通过α受体对抗针刺镇痛。α受体在脑内有α_1和α_2两种,它们对电针镇痛的影响如何?本文研究特异作用于α_2肾上The role of central nor-epinephrine(NE)in electroacupnture(EA) analyesia is a controversial question, it is probably due to the complication of adrenergic receptors. The present results show: (l)Clonidine 30ug/2ml/kg ip had no significant effect on the pain threshold, but decreased the analgesic effect of EA. Clonidine 1.5 and 3μg were injected into the lateral cerebral ventricles. After 45 minutes, the analgesic effect of EA was lowered as compared with the saline controls respectively, (2)Yohimbine had no significant effect on the basal pain threshold, but(icv Yoh 50μg)clcvatcd the analgesic effect of EA. (3)21-adrcnoceptor agonist methoxamine decreased the analgesic effect of EA, (4)Another 21-adrenoceptor antagonist prazosin(icv 16μg)enhanced the analgesic effect of EA, These results suggest that an activation of α_1- or α_2-adrenoceptors would decrease the analgesic effect of EA.866|0|1更新时间：2023-08-11
- 摘要：在针刺镇痛原理的研究中,有资料表明,低频2赫电针引起的镇痛可被甲啡肽抗体对抗,高频100赫电针镇痛可被强啡肽抗体对抗,而变频2～15赫电针镇痛既可被甲啡肽抗体、也可被强啡肽抗体对抗,Continuous 6 hour's electroacupuncture(EA) of 2-15Hz or 2Hz applying to both legs of the rats resulted in the electroacupuncture tolerance(ET). Then, we observed:(l)The effect of 2-15Hz ET on the recovery of mean arterial blood pressure(MAP) and heart rate(HR) of rats after hemorrhagic shock) (2) The change in MAP and HR of rats subjected to 2Hz ET after intrathccally(i. t.)administration of DADLE 25μg, a delta opioid agonist. The results showed that, firstly, there was no difference between 2-15Hz ET group and control group in the recovery of MAp and HR after hemorrhagic shock. Secondly, DADLE(25μg)caused almost the same suppression effect both in 2Hz TE group and in control group. These results suggest that unlike the spinal dorsal horn cells (regulating algesia, the spinal lateral horn cells (regulating blood pressure)are insensitive during EA analgesia and can not be made tolerance to continuous EA.868|0|1更新时间：2023-08-11
- 摘要：以前的实验证明,电针镇痛同时提高脑干5-羟色胺(5-HT)水平可能是通过5-HT能下行抑制起作用。大鼠给予对氯苯丙氨酸(PCPA),耗竭脑内5-HT可消除电针镇The relation between clectroacupuncture (EA)analgesia (A)and substance P (SP)level in the brain stem(BS) and lumbar sp(?)nal cord (LSC) of arthralgic rats was investigated. The rats were divided into three groups:1)5.7-dihydroxytryptamine(5·7-DHT)+EA, 2)vehicle(V)+EA, and 3)5·7-DHT. All the animals were induced arthralgesia by injecting Freund's adjuvant 7 days after cisterna injection of 5·7-DHT or vehicle. The SP level in the BS and LSC was determined by RIA. The results indicated that in V+EA group the EA could prolong tail flick latency by 39.6%, but in other two groups did not. The SP level in LSC of V+EA group (179.1±11.5pmol/g) was higher than that in the 5·7-DHT+EA (135.9+9.3pmol/g)and 5·7-DHT (125.8±10.0 pmol/g) groups. It suggested that both EA and arthralgia could activate the descending 5-HTergic inhibitory system to inhibit the release of SP in LSC, When the 5-HTergic system was destroyedby 5·7-DHT, the EAA was attenuated, and the SP level in LSC was lowered due to its release was decreased by EA and arthralgia.999|0|0更新时间：2023-08-11
- 摘要：疼痛是生理学和临床上迫切需要解决的难题,创伤又是临床上致病的主要因素之一。本文以截肢造成创伤痛,利用它具有一个发生、发展及转归的自然变化过程,动态观察了创伤引起大鼠尾及伤肢痛阈变化的规Pain threshold of rats was measured by the latent period of tail flick and limd withdrawal elicited by radiant heat. 52male SD rats were used and trauma was produced by aseptic amputation just beneath the right ankle joint. The effect of nerve block and electroacupuncture (EA) was studied and non-traumatic groups were arranged as control. The pain threshold was reduced right after trauma and the lowest level appeared on the 3rd day and then recovered gradually up to the 7th day after trauma. Nerve block and EA markedly raised the pain threshold. Particularly, EA elevated pain threshold of traumatic rats more marked and long-lasted than the effect of nerve block. This may be resulted by mobilizing the functions of the endogenous analgesic systems.819|0|2更新时间：2023-08-11
- 摘要：经国家科委批准,第二届国际蜂疗保健、蜂针疗法学术研讨会订于1993年9月28日至29日在南京召开,同期举办国际蜂疗保健品博览会(参展品评奖,评审委员会由9国专家组成)。两会由国际蜂疗保健和蜂针研究会筹委会、中国养蜂学会蜂疗保健专业委员会等主办,江苏省对外科技交流中心、连云港市蜂疗医院承办。1993年9月30日将在世界卫生501|8|0更新时间：2023-08-11
- 摘要：在内源性痛调制系统中,中缝大核(NRM)及邻近结构的神经元轴突行向脊髓后角,其释放的5-羟色胺(5-HT)可能对后角内痛敏神经元,中间神经元以及初级传入5,6-dihydroxytryptamine was microinjected into the nucleus raphe magus (NRM)of rate. The sections of upper cervical segments were processed for immunoreaclive substance P (SP). The degenerated axon terminals and immunoreactive fibers were identified by electron microscopy. The results show that the degenerated axon terminals and immunoreactive positive dendrites and axons were found in the laminae I and II of the dorsal horn. The electron-dense axon terminals were in contact with unlabelled dendrites, some also in contract with immunoreactive dendrites. In lamina II, one of degenerated axon terminals as a center was contacted by several unlabellcd axonal boutons. SP labelled terminals were synapsed with unlabelled dendrites and dendritic spinej in addition, unlabelled axo-axonal synapse was found in lamina II. These results suggest that 5-HT axon terminals from NRM directly innervate SP and non-SP neurons in the laminae I and II.754|0|0更新时间：2023-08-11
- 摘要：中缝背核(dorsal raphe nucleus,DR)头端平动眼神经核尾极,尾端达背侧被盖核水平,其背面紧邻第四脑室底头端及中脑导水管尾端腹面,在滑车神经核的水平,DR可进一步分为背正中亚核、腹内侧亚核This experiment was carried out on 35 rats with stereotaxic apparatus following a new coordinate which was designed by ourselves. The microelectrode was pushed into the lateral dorsal raphe nucleus(LDR)under direct vision. The neurons with regular rhythm and slow firing rate were searched by intracellular recording, then the singular cell in LDR was filled with HRP by intracellular iontophoresis. Results: 7 HRP labelling neurons with serotoninergic firing characteristics were observed in LDR. The labelling dendrites were found in neighboured structure(periaqueductal gray, laterodorsal tegmental nucleus, dorsal tegmental nucleus, 4th ventricle). This work demonstrated that LDR plays some role in acupuncture analgesia.859|0|0更新时间：2023-08-11
- 摘要：耳针的应用早就受到重视,对多种疾病的临床观察已肯定了耳针的疗效。采用耳压法治疗胆石症也有显著的临床效果,近年来的病例日益增多。然而,其作用In this experiment, several ultrastructural parameters of Gray's type I synapses in nucleus originis dorsalis nervi vagi were abservcd and quantitati- vely analysed by use of electron microscopy in condition gallbladder coniraction by stimulating the auricular liver-gall actpoint of rabbits with electrode. It was found that the synaptic contact length was increased extremely significantly, and the postsynaptic thickening length lengthened significantly. There were no changes in the area and the perimeter of presynaptic bouton as well as synaptic vesicle density. The percentages of synaptic perforation and negative synaptic interface tended towards increase. But there were no differences in synapses of positive and straight interface. It is suggested that the nucleus isinvoived in the regulation of gallbladder activity induced by auricular acupoint stimulation.708|0|0更新时间：2023-08-11
- 摘要：很早就有人发现,外周神经逆向刺激可引起外周神经血管的扩张和血浆渗出,用染色剂注入血管与血浆蛋白结合后随血浆渗出可在被刺激的神经支配区域皮肤上The neurogenic inflammation caused by antidromic stimulation of the saphenous nerve was taken as an index of peripheral release of substance Po Electroacupuncture could reduce the plasma extravaation from the neurogenic infilaruination by 69.7%, but electroacupuncture per se did not cause obvious plasma extravasation. In rats pretreated with capsaicin the plasma extravasation could be markedly reduced, in consistent with the reduction of substance P-like immunoreactivity in dorsal horn. It is referred that electroacuPuneture might block the conveying the signals induced by nerve stimulation along the C-fibers and the axo-axonal reflex, leading to the reduction of peripheral releease of substance P. Besides the mediation by different central structures, acupuncture might have direct effects on regulating peripherally the release of some inflammatory and painful mediators.848|0|2更新时间：2023-08-11
- 摘要：为了解针刺对热病的影响,我们设计了几种不同针刺手法施于内毒素致热的家兔模型,以冀对针刺的效应及不同针刺手法的差别有一个比较清晰的认识,并就教于同道。752|0|1更新时间：2023-08-11
- 摘要：以往工作表明,中枢内精氨酸加压素(Arginine vasopressin,AVP)和催产素(oxytotin,OXT)对针刺镇痛有重要的调节作用。然而和AVP和OXT通过中枢内何种神经结构参与针刺镇痛,目前国内外报道尚不多。本工作采用核团微穿刺技术结合放射免疫分析技术(Radioimmunoassay,RIA),检测针刺时大鼠中枢和血浆内AVP和OXT含量变化,探讨AVP和OXT参与针刺镇痛的神经结构。741|0|3更新时间：2023-08-11
- 摘要：我们曾用不同针术刺激同一穴位,在相关的皮神经和肌神经上都可引导出各具特征的、可以作为针下反应对比性指标的“针刺诱发电位图”,进而指出皮神经和肌神经中传导针刺信息的纤维类别亦因针术不同而有差异。这些现象的出现必然和浅、深感受器的针刺反应有着不可分割的内在联系。本文报导不同术式针刺与皮肤感受器放电反应的规律性关系。755|0|1更新时间：2023-08-11
- 摘要：《世界针灸杂志》是世界针灸学会联合会主办,中国中医研究院针灸研究所承办,是世界针联的国际性专业性杂志,面向国内外公开发行,季刊,英文版,16开本,印刷精良。本刊宗旨:弘扬中华传统文化的精粹——中医针灸学,促进世界各国针灸界之间的了解与合作,加强国际间的针灸学术交流,不断提高针灸学术水平,为人类健康保健事业服务。读者701|28|0更新时间：2023-08-11
- 摘要：中华人民共和国国家标准《文后参考文献著录规则》(GB7714-87)中规定:“引用文献的标注方法可以采用顺序编码制,也可以采用‘著者一出版年’制。”本刊采用顺序编码制。 1 顺序编码制的书写格式顺序编码制在文内书写的要求是按引用文献出现的先后顺序连续编码,并酌情按下述3种格式中的一种,将序号置于550|9|0更新时间：2023-08-11
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