摘要:为探索激光照射足三里穴对老年人左心功能的影响,我们于1985年9—10月对10例健康老年人进行了测试观察。现将观察结果总结如下: (一)一般资料:观察测试对象均系无明显器质性疾息,近期内未患病也未服药之健康老年人。平均年龄为65.0±1.9岁。男女各5例。 (二)方法:于激光穴位照射前后用ZK-1型阻抗血流图仪,于自由呼吸状态下,在RM—150上同步描记心电图、心音This article reports that the left heart function of the aged can be im- proved by He-Ne laser radiation on left Zusanli point. After radiation on left Zusanli point by He-Ne laser. some changes of the left heart fu- nction have been showed as follows: decreasing of heart rate, shortning of PEP, prolonging of LEVT and reducing of the ratio of PEP/LVET.
摘要:用胃肠电活动作为胃肠功能和胃肠道疾病诊断和判定疗效的指标,已进行数十年的研究,但到目前为止,仍存在很多问题,为将胃肠电活动应用于临床,作为针麻胃肠道手术和胃肠道疾病时胃肠功能变化的指标,我们研究了狗胃肠道电活动的基本规律,以作为临床应用的参考。实验方法用狗为实验动物,雌雄不拘,体重为10~18公斤,在戊巴比妥钠(Pentobarbi-tal sod)麻醉下,按外科常规手术操作,Unanesthetized trained dogs with implanted electrodes in the stomach and intestinal wall were prepared for the study of the rhythmic pattern and characteristics of the gastrointestina electrical activity. The results were as follows: In the fasting condition, the frequency of the slow wave of the gastroelectric activity may be divided into three rhythmic patterns: (1)Slow wave or primary wave. The frequency of this wave pattern was 5.1±0.3 cycles/minute. It accounted for 92% of the whole experiment.(2)Fast slow- wave. The frequency of this wave pattern was 13.4±1.7 cycles/minute and it accounted for 7.4% of the whole experiment.(3)Premature slow-wave. This happened just like an extra-systole of the heart. The premature slow- wave was always followed by a compensatory pause. This wave pattern occurred in the experiments very often. In the fasting condition,an alterna- tion cf period of quiescence and electrical spiking activity occurred at regular intervals. It was called interdigestive myoelectric complex(IDMEC). The cycl'c activity of the interdigestive myoelectric complexes of the sto- mach and small intestine may be changed by both splanchnicotomy and vagotomy, and by intravenous injection of atropine or hexamethonium, in- travenously or cerebral intraventricle injection of morphine or gastin and by subcutaneous local abscesses. Acupuncture at "Zusanli" had little effects on the slow wave of the gastroelectric activity, bur as a result of acupu- ncture the amplitude and frequency of the fast wave increased. In normal animals acupurcture at Zusanti" had no effect on the interdigestive myo- electric complex bat an obvious regulatory action of the IDMEC on the dogs with subcutansous local abscess was observed.
摘要:消化道疾病是一种常见病、多发病,至今对胃肠道疾病诊断的检查方法有X线钡餐造影、纤维内窥镜等。长期来中医针灸临床常取足三里穴为治疗肠胃道疾病的主穴。而且国内已有不少工作证实足三里穴对胃肠道生理功能确有一定的影响,但缺乏一种无痛苦的客观记录。自Alyarez等从人的腹壁体表记录到胃电后,许多学者都企图应用胃电作为胃机能活动的指标研究胃的生理病理规律,希望胃电能作为胃疾患临床诊断和Using a untraumatic method of the surface electrode unipolar leads, the electrogastrogram (EGG) and tbe effect of needling reaction appeared on EGG were recorded in 40 normal subjects and 104 patients suffering from gastroduodenal disease. 1. In 40 normal subjects the average values of frequency and amplitu- de of EGG were 3.26±0.06 c/min. and 181.6±16.91μV respectively before dinner the frequency and amplitude of EGG were 3.21±0.06 c/min. and 236.2±17.30μV, respertively after dinner. 2. Before dinner the average frequency and amplitude of EGG were 3.29±0.1 c/min, and 229.4±28.5μV in 8 cases with gastric ulcer, 3.26± 0.33 c/min, and 261.9±66.6μV in 36 cases with duodenal ulcer, 3.14±0.14 c/min and 159.7±25.5μV in 10 cases with duodenitis, 3.40±0.05c/min.and 50.14±8.72μV in 41 cases with surficial gastritis, 3.33±0.18 c/min, and 47.58±4.12μV in 7 cases with atrophic gastritis and 3.16±9.71 c/min. and 43.1±16.7μV in 2 cases with gastric cancer. After dinner the mean frequency and amplitude of EGG were as bellow: 33.3±0.22 c/min and 351.5±51.6μV in the gastric ulcer cases, 3.21±0.06 c/min.and 327.8±49.4μV. in the duodenal ulcer cases, 2.96±0.5 c/min and 218.3±50.2 μV the duodenitis eases, 3.30±0.05 c/min, and 119.1±14.3μV, in the surficial ga- stritis cases, 3.52±0.16 c/min, and 54.74±19.14μV in the atrophic gastritis cases, 3.50±0.84 c/min and 53.4±2.98μV in tha gastric cancer cases. The above results show that after dinner the amplitude of EGG incr- eased significantly, but the frequency did not change significantly. 3. In the 12 patients with gastroduodenal disease before acupunctur- ing Zusanli acupoint, the mean amplitude of EGG was 276.3±55.7 μV. When neediling reaction appcared, the mean amplitude of EGG increased to 459.7±90.67 μV. When the needie manipulation was stopped the amplitude of EGG decreased to 355±92.67μV, but the frequency of EGG did not have significat change. 4. The results in observing the relation of TCM differentiation of syndromes with EGG were as bellow: Among 89 patients with epigastric pain, 50 cases were with Xu type of the spleen and stomach miningled wi- th cold type, 5 cases with syndromes of Yin Xa, 6 cases with Xu of the spleen and stomach with cold accompanied attach on stomach by liver Qi type, the amplitude of EGG was lower than that of the normal subjects, but in 21 cases with simple attach on stomach by liver Qi type and in 5 cases with accumulation of heat in the liver and stomach the mean ampli- tude were higher that of the normal subjects.
摘要:近年来,大量的针刺镇痛研究资料表明,大脑皮层体感Ⅰ区(SⅠ区)和丘脑中央外侧核与痛和针刺镇痛关系密切。如电刺激猫牙髓,可在皮质体感Ⅰ区记录到由Aδ传入纤维引起的皮层诱发电位。当电针“下关”等穴时,则可抑制皮质体感Ⅰ区内的这种诱发电位。表明皮质体感Ⅰ区即可以接受痛信息,又可接受针刺穴位的信息。中央外侧核是丘脑内参与针刺镇痛的重The origin of the somato-sensory area I(SI) projecting to the central lateral nucleus(CL) was studied with the method of horseradish peroxidase (HRP) in the cat. Following the introducing of HRP into the central la- teral nucleus, numerous labeled cells, which belong to the medium-sized pyramidal cells(20-28u), were found in layer V of the ipsilateral SI area.
摘要:间使穴为手厥阴心包经的穴位,位于前臂掌面的下段。针灸学简编中认为在腕上三寸,掌长肌健与桡侧腕屈肌腱之间,“主治突然心痛,心悬如饥”,此外对中风、癫狂及小儿惊厥、精神病等亦可治疗。王雪苔著的针灸学手册认为除治心区痛等病证外尚可治疗急性心包炎、小儿夜啼、神经性呕吐及慢性低热等症。由于间使穴是手厥阴心包经的主穴,又具有可以主治心痛及心10 cats were used in the present experiments. 60μl of 15-20% HRP wasinjected into the left nerve trunks of point "Jianshi" and right point "Jianshi". After 5 days of survival the heart was perfused with 1% para- formaldehyde and 1.25% glutaformal dehyde in 0.1M phosphate acid buffered at PH 7.4. the sixth cervical to second thoracic spinal ganglions (G_6-T_2) were cut and treated according to Edward (79) O-D and Mesulam TMB method, and the reactions were made out. In the seventh to eighth cervical spinal ganglions and first thoracic s- pinal ganglions HRP labeled cells (C7-8, T1) were found. Most of them were present in C8 and T1, while in C7 labeled cells were less. The large, middle and small labeled cells coexisted. In the efferent neurons of the anterior horn of C8-T1 spinal cord, we also fotind the labeled cells. The essential afferent neurons of point "Jianshi" located in the C7-T1 spinal ganglions. It is different from the location of the afferent neurons of the median nerve (C5-T1). This study has proved the segmenta1 distri- butions of afferent neurons of the heart and "Jianshi" point are overlappe- d. This overlap may be the morphologic foundation for the treatment of heart diseases by acupuncturing "Jianshi" Point.
摘要:很多实验证明中枢单胺类递质与针刺镇痛作用有关。我室对实验性电针镇痛的大鼠同时测定中枢单胺类递质表明,脑干的5-羟色脓增高,端脑去甲肾上腺素轻度下降。当用对氯苯丙氨酸耗竭脑内5-羟色胺时,可消除大鼠的针刺镇痛作用。北医针麻组也有类似的结果,而且证明5-羟色氨酸能加强针麻镇痛的效果。然而中枢儿茶酚胺在针刺镇痛中的作用比较复杂,实验报道较Rats that were not affected by acupuncture were selected and α-methyl- tyrosine (50mg/kg I.P.) in one dosage was given to inhibit the synthesis of catecholamine (CA) in CNS. Four hours after the injection the nore- epinephrine decreased by 45%, dopamine by 30% in three regions of the brains, respectively. Meantime, eletro--acupuncture was given to the animals. To compare with the control, the basic threshold of pain was no changed, aud also no change of the effect of acupuncture analgesia could be seen. The result suggested that the inhibition of the catecholamine sy- nthesis to decrease the level of CA in CNS is no effect on the acupunctu- re analgesia. The function of CA in CNS on the acupuncture analgesia n- eeds to use the more approaches to investigate further.
摘要:脑脊液(CSF)中钠/钙比例升高,体温则升高;钠/钙降低。体温则降低。在电针降温过程中,CSF钙离子(Ca(++))含量升高,而(Na(++))含量升高,而(Na+)钠离子含量无变化,提示电针降温与CSFCa+)钠离子含量无变化,提示电针降温与CSFCa(++)含量升高有关。为了进一步分析CSFCa(++)含量升高有关。为了进一步分析CSFCa(++)含量的变化与电针降温的关系,本文分别观察了电针对发热家兔的降温作用和给去钙剂EDTA·2Na后对电针降温作用的影响。方法实验是在24只体重为2.0~2.9公斤的家兔上进行,性别不拘。在25%乌拉坦(1克/公斤)静脉麻醉下,行暴露枕骨大孔术,以备抽取CSF。待动物完全恢复清醒(麻The experiments were carried out on 24 conscious rabbits. The results suggest that electroacupuncture caused a fall in body temperature of the rabbits with hypethermia and the Ca(++)含量的变化与电针降温的关系,本文分别观察了电针对发热家兔的降温作用和给去钙剂EDTA·2Na后对电针降温作用的影响。方法实验是在24只体重为2.0~2.9公斤的家兔上进行,性别不拘。在25%乌拉坦(1克/公斤)静脉麻醉下,行暴露枕骨大孔术,以备抽取CSF。待动物完全恢复清醒(麻The experiments were carried out on 24 conscious rabbits. The results suggest that electroacupuncture caused a fall in body temperature of the rabbits with hypethermia and the Ca(++) content in CSF increased markedly at the same time. But when tal decalcifying agent (EDTA.2Na) was inje- cted intraperitoneally, the body temperature and Ca(++) content in CSF increased markedly at the same time. But when tal decalcifying agent (EDTA.2Na) was inje- cted intraperitoneally, the body temperature and Ca(++) content in CSF did not change after electroacupuncture. It is indicated that the Ca(++) content in CSF did not change after electroacupuncture. It is indicated that the Ca(++) content in CSF may play an important role in falling temperature by electroacpu- neture.
摘要:由延髓下端到中脑头端、脑干中缝两旁,有相对集中的中缝核。人、猫、兔和鼠的中缝核,由尾侧向头端均可分成下述八个核团:中缝隐核、中缝苍白核、中缝大核、中缝桥脑核、中央上核、中缝背核、线形中核和线形上核。在中枢神经内,5-羟色胺(5-HT)神经元主要分布在中缝核及其邻近的网状结构内。中缝核的联系相当广泛,共机能是多方面的。近来研究表明,它在针刺镇痛中起重要作用。 (一)损毁或电刺激中缝核对针刺镇痛的影响无论以电针刺激大鼠尾部引起嘶叫反应测痛,还是以刺激大鼠牙髓诱发的皮层This Paper reviews the main results of a few recent years' study on the relationship between raphe nuclei and acupuncture analgesia. 1. Acupuncture analgesia was significantly reduced after lesion of r- aphe nuclei, but was increased by stimulation of raphe nuclei. Spontane- ous discharges of raphe nuclei neurons were activated, but the innociceptive responses were inhibited by acupuncture. The results show that raphe nuclei play an important role in acupuncture analgesia. 2. Metabolisms of 5-HT and NE in raphe nuclei produced obvious c- hanges in acupuncture analgesia. Also, acupuncture analgesia was inhibit- ed by microinjectin of 5,6-DHT or naloxone into raphe nuclei. Therefor- e, it is suggested that 5-HT, OLS and NE etc. in raphe nuclei may be parts of the substanes involied in acupuncture analgesia. 3. In acupuncture analgesia, activities of raphe nuclei were regulated by some hiqher analgesic structures of the brain, for example, N. cauda- te, N.accumbens and PAG etc. In addition, nucleus raphe magnus possibly performed descending inhibitoy effect on pain transmission in the spinal cord; Pain reactivity could be regulated by nucleus raphe dorsalis and nu- cleus raphe medianus. Further studies on interactions between neurochemical substances wit- hin raphe nuclei and between raphe nuclei and other central analgese stru- ctures of the brain in acupuncture analgesia are still necessary.