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1.天津中医药大学,天津 301617
2.天津市中医药研究院附属医院,天津 300120
张智龙,E-mail:275981918@qq.com
收稿:2025-02-08,
修回:2025-03-18,
网络首发:2026-05-06,
纸质出版:2026-05-25
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蒋楚璠,王栩,肖遥,等.基于数据挖掘探讨针灸治疗糖尿病肾病的分期、证型、症状选穴规律[J].针刺研究,2026,51(5):678-686.
JIANG Chu-fan,WANG Xu,XIAO Yao,et al.Rules of acupoint selection for different stages, syndromes and symptoms of diabetic nephropathy treated with acupuncture based on data mining[J].Acupuncture Research,
蒋楚璠,王栩,肖遥,等.基于数据挖掘探讨针灸治疗糖尿病肾病的分期、证型、症状选穴规律[J].针刺研究,2026,51(5):678-686. DOI: 10.13702/j.1000-0607.20250207.
JIANG Chu-fan,WANG Xu,XIAO Yao,et al.Rules of acupoint selection for different stages, syndromes and symptoms of diabetic nephropathy treated with acupuncture based on data mining[J].Acupuncture Research, DOI:10.13702/j.1000⁃0607.20250207.
目的
2
通过数据挖掘技术探讨针灸治疗糖尿病肾病(DKD)各分期、证型及症状的选穴规律。
方法
2
检索自建库至2025年1月1日中国知识基础设施工程(CNKI)、万方数据知识服务平台(Wanfang)、维普资讯中文期刊服务平台(VIP)、中国生物医学文献数据库(SinoMed)、Cochrane Library、Embase、Web of Science、PubMed数据库中针灸治疗DKD的文献。使用中医传承辅助平台系统进行频次统计。通过SPSS Modeler 18.0软件Apriori算法,对DKD的各个分期及其主要证候类型和症状的穴位配伍进行关联规则挖掘,使用Cytoscape软件绘制共现网络图。
结果
2
共纳入119篇文献,涉及62个腧穴。针灸治疗DKD早期腧穴使用频次(260次)及个数(27个)最多,以益气养阴、活血化瘀为主,多选用足三里、三阴交、血海;临床期以补益脾肾,化瘀泻浊为主,多选用肾俞、脾俞、关元、阴陵泉;终末期以扶阳固本,化浊解毒为主,多选用脾俞、命门、关元、神阙;各证型分别以三阴交-太溪、脾俞-关元、足三里-中脘、血海-膈俞等辨证取穴为主;各症状高频腧穴为关元、膏肓俞、水道、大敦等辨症取穴为主。19篇采用症状相结合选穴文献中,“水肿”出现频次最多。
结论
2
各分期中腧穴使用频次最多的经脉均为足太阳膀胱经,肾俞-足三里为各分期和各证型的高频穴对。临床可采用分期、证型、症状相结合的方式选穴。
Objective
2
To explore the rules of acupoint selection for different stages, syndrome types and symptoms of diabetic nephropathy (DKD) treated with acupuncture by means of data mining technology.
Methods
2
Literatures on acupuncture for DKD were retrieved from China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, VIP Chinese Journal Service Platform, SinoMed, Cochrane Library, Embase, Web of Science and PubMed databases from their inception to January 1, 2025. Frequency statistics were performed using the Traditional Chinese Medicine Inheritance Support System. Apriori algorithm in SPSS Modeler 18.0 software was adopted to analyze the association rules of acupoint compatibility for different stages, main syndrome types and symptoms of DKD, and Cytoscape software was used to draw the co-occurrence network diagram.
Results
2
A total of 119 literatures were included, involving 62 acupoints. The frequency (260 times) and number (27 acupoints) of acupoint application in the early stage of DKD treated with acupuncture were the highest, focusing on replenishing
qi
and
nourishing
yin
, promoting blood circulation to remove blood stasis, and Zusanli (ST36), Sanyinjiao (SP6) and Xuehai (SP10) were mostly selected; in the clinical stage, the treatment focused on tonifying the spleen and kidney, removing blood stasis and purging turbidity, and Shenshu (BL23), Pishu (BL20), Guanyuan (CV4) and Yinlingquan (SP9) were mostly selected; in the end stage, the treatment focused on strengthening
yang
and consolidating the root, resolving turbidity and detoxifying, and BL20, Mingmen (GV4), CV4 and Shenque (CV8) were mostly selected; for different syndrome types, acupoints were selected based on syndrome differentiation, such as SP6-Taixi (KI3), BL20-CV4, ST36-Zhongwan (CV12), SP10-Geshu (BL17); for different symptoms, high-frequency acupoints were selected based on symptom differentiation, such as CV4, Gaohuangshu (BL43), Shuidao (ST28) and Dadun (LR1). Among the 19 literatures adopting symptom-combined acupoint selection, "edema" had the highest frequency of occurrence.
Conclusion
2
The Bladder Meridian of Foot-Taiyang was the meridian with the highest frequency of acupoint application in all stages, and BL23-ST36 was the high-frequency acupoint pair in all stages and syndrome types. Clinically, acupoint selection can be performed by combining stages, syndrome types and symptoms.
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