最新刊期

    1 1995
    • Issue 1, Pages: 1-4(1995)
      摘要:The observation on the indexes of cortisol. estradiol.estriol and testosterone showed that incretory function of malignant tumor patients had different extent of pathologic changes, after radiotherapy and chernotherapy, making the change strengthened;Acupuncture can regularize this disorder of incretory function of patients treated with radiotherapy and chemotherapy to some extent  
        
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    • Issue 1, Pages: 5-9(1995)
      摘要:The experiment was carried out on rats. Unit d1scharges of NRM were recorded extracellularly with glass microelectrode.Before the lesion of the head of N.Caudatus,15 NRM neurons were recorded.The stimulation of the hindlimb areas of SM could obviously activate NRM neurons,the spontaneous discharges were increased to 59.06±25. 35 % (P<0.05) and the nociceptive responses were obviously inhibited to-46. 61±14.78 (P<0.01) at 0minute after stopping stimulation, Both effects lasted for 15 minutes,and then gradually returned to original level.After the lesion of the head of N. Caudatus,the effects of the stimulation of the hindlimb areas of SM on 19 NRM neurons were clearly decreased.The spontaneous discharges were increased to only 6. 9±21. 46 % and thenociceptive responses were inhlbited only - 4. 57±11.08 % at 0 minute after stopping stimulation,even the nociceptive responses were slightly increased in 5 - 30 minutes, The difference between the two groups was statistical significance,The value of the difference was about 42 % (P<0.05 ) at 0 minute and lasted 30 minutes.It suggests that the effects of stimulating SM on NRM may be transmitted by the head of N. Caudatus in the extrapyramidal system  
        
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    • Involvement of Opioid Peptides in Corticofugal Modulation of Pain

      Issue 1, Pages: 10-14(1995)
      摘要:The effect of opioid peptides on corticofugal modulation of nociceptive response in thalamic ventrobasal nucleus (VB) produced by cortical sensorimotor area Ⅱ (Sm Ⅱ) was observed.Single unit activities of VB neurons were extracellularly recorded by glass microelectrodes.The results showed that the nociceptive responses of VB neurons were attenuated at 0- 7. 5 minutes after stimulating Sm Ⅱ(n=14, P<0.05). The inhibitory effect of stimulation of Sm Ⅱ was reduced after ventriculer microinjection of 20ul of naloxone (n=9), while marked inhibition was shown at 0- 2. 5 minutes after stimulating Sm Ⅱ in the saline control group (n= 9, P<0.05). There was a statistical difference at 0 - 2. 5 minutes after stimulating Sm Ⅱ between the two groups (P<0.05). These studies suggest that opioid peptides might be involved in corticofugal modulatio of pain  
        
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    • Issue 1, Pages: 15-19(1995)
      摘要:This study aimed to investigate the role of ACh in SmI emanating descending modulation of thalamic Pf neurons in acupuncture analgesia.Multi-micropipettes were used for both extracellularly recording responses of thalamic Pf neurons to noxious stimulation of the plantar area and drug application in rats.It was found that (1) lesion of SmI obviously attenuated the inhibitory effect of EA applied at "Zusanli"and "Huantiao"points on nociceptive responses in Pfneurons; (2) after lesion of Sml iontophoretic application of ACh markedly suppressed the nociceptive responses of Pf neurons, which was significantly different from the effect of iontophoretic NaCl (as the control) showing no influence on them; (3)the inhibition induced by iontophoretic ACh applied in the rats with lesion of SmI was similar to that produced by EA applied in those with SmI intact.It is indicated that EA can activate SmI to release ACh to exert descending modulation, in which ACh is involved in SmI originating descending regulation of Pf neurons in acupuncture analgesia  
        
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    • Issue 1, Pages: 20-23(1995)
      摘要:The discharges of pain-sensitlve neurons of the hypothalamic dorsomedial nucleus (DMH) in Sprague-Dawley rats were recorded with glass microelectrodes, After electroacupuncture acupoints" Zusanli"and "Sanyinjiao", the rate of spontaneous discharges and the rate and duration of the pain-evoked discharges of pain-excitatory units of DMH were pro foundly decreased,and the spontaneous firing rate of pain-inhibitory units was increased while their inhibitory response to nociceptive stimulation was released by the electroacupuncture.The results mentioned above suggest that DMH participates in the activity of acupuncture analgesia  
        
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    • Issue 1, Pages: 24-30(1995)
      摘要:Our privious work have demonstrated that eletroacupuncture (EA) at acupoints seemed to have no specific effects.The present work is to observe whether the analgesic extensiveness and specificity of EA at points is related to EA intensity and the sites of points.Experiments were carried out on rats anaesthetized with Urathane.The spontaneous discharges and nociceptive responses of convergent neurons on right trigeminal dorsl horn to noxiope stimukition at receptive field (cheek)were recorded extracellarly with glass micro-electrode. EA was applied at ipsilateral "Xiaguan" (on face ) or" Zusanli" (on shank)point with low (2V) and high (18V) intensity. The nociceptive response of TCN could be inhibited by low intensity EA applied at "Xiaguan"but not "Zusanli", shnwing the specificity of points.High intensity EA at either "Xiaguan" or Zusanli" also reduced the responses,showing the analgesic extensiveness of points.We suggest that "the gate of control" mechanism plays an important role in low intensity EA and "DNIC" mechanism does so in high intensity EA.The results suggest that we must pay attention to the manipulation and the intensity of acupuncture in the clinic work  
        
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    • Issue 1, Pages: 31-35(1995)
      摘要:The Subunit αo of guanine nucleotide-binding protein(rabbit polyclonal antiserum 9120, K,J.Chang.USA),in the areas of rat spinal cord was localized by immunohistochemical PAP methods,and the changes of αo-immunoreactivity (αo-IR ) in the substantia gelatinosa (SG) were observed after unilateral tranartion of dorsal roots and electroacupuncture.Intense αo-IR was presented in Rexed lamina Ⅰ to Ⅲ of the dorsal horn,and the highest αo-IR in lamina(SG), which was found than that in the normal and control animals.Iateral spinal nucleus of rat revealed higher density of αo-IR containing fiber networks.Following unilateral transection of dorsal roots and pain threshold increased significantly after electroacupuncture applied at the point "Huantiao",αo-IR was markedly decreased than that in the normal and control group in those areas.The optic density(OD) of αo-IR were measured,which decreased more markedly in opration and electroacupuncture group than that normal and control gruoup.The results mentioned above indicate that Go-protein in terminals of primary nociceptive neurons of SG decreases markedly after dorsal roots transected and electroacupuncture.It was inferenced that partial Go-protein probably originates from the primary sensory neurons, and the release of "inhibitory"of Go may increase(with weaker αo-IR).In a work. Go might playimportant roles on the primary afferents informational regulation and electroacupuncture analgesia of the regulation  
        
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    • Issue 1, Pages: 36-39(1995)
      摘要:Lymphocyte proliferation of splenocytes induced by concanavalin A(Con A) and the induction of IL-2 production test were used to study the effects of acupuncture on immunomodulation by stimulation of Zusanli(ST 36) and Lanwei (Extra 33) points of the rat's left leg.It was observed that the lymphocyte proliferation of splenocytes was increased in EA groups of 3 days (p<0.05),5 days (p <0.001) and 7 days (P<0.05).The parabolical curve could be found by currilinear regression (R2 =0.9901).EA groups of 3 days and 5 days had a significantly increased induction of IL-2 production (P<0.05).These results will be helpful to choose an optimal time for clinical treatment  
        
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    • Issue 1, Pages: 40-43(1995)
      摘要:1. In normal control mice (only injected SRBC) after EA the lymphocyte transformation test (LTT, P<0.05) and interlukin-2 (IL-2) activity (P<0.05) were significantly increased,but the serum lysozytne (IZM,P<0.01) was apparantly decreased.2.After in jection of 6-OHDA in mice, the spleen weight, spleen index,thymus weight, thymusindex,spleen lymphocyte population and serum IZM, igG contents were marked deceaseds,Whereas LTT, IL-2 and plaque forming cell(PFC) were umchanged,In contrast,the thymus lymphocyte population was markedly increased.3. After EA of mice axotomized sympathetic nerve with 6-OHDA the above mentioned immune parameters deceased by 6-OHDA could be returned to normal or nearing normal levels.HOwever,the unchanged LTT, IL-2 and the increased thymus lymphocyte population could be enhanced further,especially IL-2.These results suggest that peripheral sympathetic nerve may be participation in the EA-mediating Anmunological responses  
        
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    • Issue 1, Pages: 44-47(1995)
      摘要:This paper reports the study of the effect of the cardiac function and arterial pressure on rabbits with hemorrhagic shork by electro acupuncture Neiguan point.The result showed that PEP was shortened,ET was lengthened,SV, CO and Map were raised by needling Neiguan and the each index was significant difference (P<0.001). Above results indicated that needling may strengthen myocardisl contractile force,protect the cardial pump function, raise the blood pressure, play a positive role during anti- hemorrhagic shock  
        
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    • Issue 1, Pages: 48-53(1995)
      摘要:This article is focused on the observation of changes in body temperature, body weight,cholinesterase activity in blood,and gastrointestinal motility of reserpinized rats treated by stimulating Zusanli (ST 36)with moxibustion of different quality.(mugwort floss or pipe tobacco) and quantity (strong stimulation or weak stimulation).The experiment shows that better results are achieved with moxibustion not by burning tobacco;the result of tstrong stimulation with moxa-sticks is better than that of weak stimulation with the same material.Strong stimulation with moxa-sticks can obviously increase the activity of cholinesterase (P<0.05),inhibit hyperactive gastrointestinal motility (P<0.05),maintain normal body temperature (P<0.05),and prevent they weight lossing.All these show that therapeutic results of moxibustion are closely related to the quality and quantity of moxibustion  
        
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    • Issue 1, Pages: 54-59(1995)
      摘要:This work is to study whut the analgesia of EA is related with specificity of channel point or innervatinu of point. The discharges of 28 NRM neurons and their nociceptive responses induced by stimulation of dental pulp or tail tip in rats were recorded.The effects of EA of "Shangguan" and "Yanglingquan"of gall bladder channel of foot shaoyang on NRM neurons and their nociceptive responses were comShangguan"and with that of and"Xiaguan"and "Zusanli"of the stomach channel of foot Yangming."Shangguan"and" Xiaguan"were located in the depressions at the upper and lower border of zygomatic arch respectively,and innervated by the n.trigeminus.The hind leg points"Yanglingquan"is located in the depression anterior and inferior to capitulum fibulae above "Zusanli" and both were innervated by n.Peroneus communis.The results showed that EA of "Shangguan"or"Xiaguan"could activateNRM,increasing unit discharges about 70120% for 10120% for 1015 minutes (P<0.0515 minutes (P<0.050.001) and inhibit both nociceptive responses,but the inhibition on the nociceptive response induced by dental pulp (about - 60% for 50.001) and inhibit both nociceptive responses,but the inhibition on the nociceptive response induced by dental pulp (about - 60% for 510 minutes, P<0.0510 minutes, P<0.050.001) was stronger than that by tail-tip (no effect or about-30% occasionally). "Yanglingquan"or "Zusanli" EA could also activate NRM and inhibit the nociceptive responses, but the inhibition on the nociceptive response of tail stimulation (about - 600.001) was stronger than that by tail-tip (no effect or about-30% occasionally). "Yanglingquan"or "Zusanli" EA could also activate NRM and inhibit the nociceptive responses, but the inhibition on the nociceptive response of tail stimulation (about - 60- 40% for 30 minutes, P<0.05- 40% for 30 minutes, P<0.050.001) was stronger and longer than that of dental pulp (about-40% for 50.001) was stronger and longer than that of dental pulp (about-40% for 510 mintues, P<0.0510 mintues, P<0.050.001).It is suggested the analgesia of acupuncturing facial points and hind leg points is better on toothache and on tail pain respectively,but there is no difference in analgesic effect of point in the channel line from other one.It may be related to that,the information from point and pain area is converged in the same and proximal spinal segment  
        
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    • Zheng Daming
      Issue 1, Pages: 67-71(1995)
      摘要:This paper discusses the bioelectric information. It introduces the range of bioelectric information,the hypothesis of two templates of bioelectric information in organisms, the meaning of drawing and input bioelectric information and the principle and application of the technology for recording and input bioelectric information. Based on all above it suggests a possibility of establishing a new acupuncture technique of bioelectnic information,it also suggests a new direction in studies of bioelectric infor -mation and an application of the new method in clinical diagnosis and treatment  
        
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